SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MQ7'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Thermus
thermophilus) 		4 / 6 HIS C  21
TRP C  14
PHE C  22
VAL C  25
 MQ7  C1252 (-4.1A)
MQ7  C1252 ( 4.5A)
None
None
 1.06A 1ibgH-2vpwC:
undetectable		 1ibgH-2vpwC:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Thermus
thermophilus) 		5 / 12 TYR C 130
VAL C  25
ASP C  60
ASN C  18
ILE C  89
 MQ7  C1252 (-4.4A)
None
None
MQ7  C1252 (-3.1A)
MQ7  C1252 (-3.8A)
 1.43A 2dcfA-2vpwC:
undetectable		 2dcfA-2vpwC:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Thermus
thermophilus) 		5 / 12 GLY C 103
GLY C  97
GLY C  99
LEU C  61
LEU C  64
 None
None
None
None
MQ7  C1252 (-3.5A)
 0.98A 2zbpA-2vpwC:
undetectable		 2zbpA-2vpwC:
28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Thermus
thermophilus) 		5 / 12 TYR C 130
VAL C  25
ASP C  60
ASN C  18
ILE C  89
 MQ7  C1252 (-4.4A)
None
None
MQ7  C1252 (-3.1A)
MQ7  C1252 (-3.8A)
 1.40A 3a65A-2vpwC:
undetectable		 3a65A-2vpwC:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
(Thermus
thermophilus) 		4 / 6 ALA C 134
ILE C  89
VAL C  25
HIS C  21
 None
MQ7  C1252 (-3.8A)
None
MQ7  C1252 (-4.1A)
 1.15A 3nneG-2vpwC:
undetectable		 3nneG-2vpwC:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN
NRFC PROTEIN
(Thermus
thermophilus) 		5 / 12 VAL B  85
PRO B  87
ALA B  74
ILE B  91
SER C  68
 SF4  B1197 ( 4.8A)
None
SF4  B1197 ( 4.0A)
SF4  B1197 ( 4.3A)
MQ7  C1252 ( 4.9A)
 1.24A 5hgcA-2vpwB:
undetectable		 5hgcA-2vpwB:
19.89