SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MPO'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZM_A_BZMA600_0 (ODORANT-BINDING PROTEIN)	1f07	COENZYME F420-DEPENDENT N5,N10-METHYLENETETR AHYDROMETHANOPTERIN REDUCTASE (Methanothermobac ter thermautotrophic us)	4 / 8	ILE A 185 MET A 157 VAL A  62 GLY A 162	None None MPO  A 331 (-3.9A) None	0.97A	1dzmA-1f07A: 0.0	1dzmA-1f07A: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E06_B_IPBB600_0 (ODORANT-BINDING PROTEIN)	1f07	COENZYME F420-DEPENDENT N5,N10-METHYLENETETR AHYDROMETHANOPTERIN REDUCTASE (Methanothermobac ter thermautotrophic us)	4 / 4	ILE A 185 MET A 157 VAL A  62 GLY A 162	None None MPO  A 331 (-3.9A) None	1.05A	1e06B-1f07A: 0.0	1e06B-1f07A: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERR_B_CCSB381_0 (ESTROGEN RECEPTOR)	1kj9	PHOSPHORIBOSYLGLYCIN AMIDE FORMYLTRANSFERASE 2 (Escherichia coli)	3 / 3	GLU A  37 ALA A  53 SER A  56	EDO  A 401 (-2.9A) None MPO  A 400 (-3.8A)	0.59A	1errB-1kj9A: 0.0	1errB-1kj9A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OLT_A_SAMA501_0 (OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE)	1f07	COENZYME F420-DEPENDENT N5,N10-METHYLENETETR AHYDROMETHANOPTERIN REDUCTASE (Methanothermobac ter thermautotrophic us)	5 / 12	GLY A 246 ILE A 227 PHE A 273 ALA A 172 GLN A 153	None MPO  A 331 (-4.8A) None MPD  A 335 ( 4.9A) None	1.34A	1oltA-1f07A: 0.2	1oltA-1f07A: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7B_A_BEZA1529_0 (BENZOATE-COENZYME A LIGASE)	1f07	COENZYME F420-DEPENDENT N5,N10-METHYLENETETR AHYDROMETHANOPTERIN REDUCTASE (Methanothermobac ter thermautotrophic us)	5 / 9	ALA A 202 TYR A 297 ALA A 299 GLY A 300 GLY A   4	None None None MPO  A 331 ( 4.1A) None	1.19A	2v7bA-1f07A: undetectable	2v7bA-1f07A: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7B_B_BEZB1529_0 (BENZOATE-COENZYME A LIGASE)	1f07	COENZYME F420-DEPENDENT N5,N10-METHYLENETETR AHYDROMETHANOPTERIN REDUCTASE (Methanothermobac ter thermautotrophic us)	5 / 9	ALA A 202 TYR A 297 ALA A 299 GLY A 300 GLY A   4	None None None MPO  A 331 ( 4.1A) None	1.20A	2v7bB-1f07A: undetectable	2v7bB-1f07A: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W8Y_A_486A1000_1 (PROGESTERONE RECEPTOR)	3ksx	NITRATE TRANSPORT PROTEIN (Xanthomonas citri)	5 / 12	LEU A 100 GLY A  84 GLN A  36 LEU A  91 VAL A 276	None None MPO  A 325 (-3.1A) None None	1.12A	2w8yA-3ksxA: undetectable	2w8yA-3ksxA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_B_D2VB602_1 (CYTOCHROME P450 2R1)	3ksx	NITRATE TRANSPORT PROTEIN (Xanthomonas citri)	5 / 12	LEU A 146 ALA A 170 ALA A  67 VAL A 117 ILE A 134	None None MPO  A 325 ( 3.7A) None None	1.09A	3czhB-3ksxA: undetectable	3czhB-3ksxA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_A_ECLA600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4n11	GLUTAREDOXIN (Plasmodium falciparum)	4 / 8	LEU A  69 THR A  70 GLY A  87 ILE A  53	MPD  A 202 ( 4.2A) None MPO  A 201 (-3.5A) None	0.74A	3jusA-4n11A: undetectable	3jusA-4n11A: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_A_ECNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4n11	GLUTAREDOXIN (Plasmodium falciparum)	4 / 8	LEU A  69 THR A  70 GLY A  87 ILE A  53	MPD  A 202 ( 4.2A) None MPO  A 201 (-3.5A) None	0.74A	3jusA-4n11A: undetectable	3jusA-4n11A: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOS_A_0LIA1004_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	3ksx	NITRATE TRANSPORT PROTEIN (Xanthomonas citri)	5 / 11	ALA A  45 LEU A 235 GLY A  83 VAL A  39 GLY A  34	None None None MPO  A 325 ( 4.9A) None	1.13A	3zosA-3ksxA: undetectable 3zosB-3ksxA: 1.1	3zosA-3ksxA: 22.79 3zosB-3ksxA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BJC_A_RPBA2162_1 (TANKYRASE-2)	3ksx	NITRATE TRANSPORT PROTEIN (Xanthomonas citri)	5 / 8	HIS A 143 GLY A 139 ALA A 142 SER A 140 GLU A 113	None None None MPO  A 325 (-4.5A) MPO  A 325 (-3.5A)	1.36A	4bjcA-3ksxA: undetectable	4bjcA-3ksxA: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1K_B_LOCB502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	3ksx	NITRATE TRANSPORT PROTEIN (Xanthomonas citri)	5 / 12	VAL A 310 LEU A  72 ALA A  93 LEU A  91 ALA A  85	None None None None MPO  A 325 (-3.7A)	0.96A	4x1kA-3ksxA: undetectable 4x1kB-3ksxA: undetectable	4x1kA-3ksxA: 24.51 4x1kB-3ksxA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UXC_A_ZITA306_1 (PREDICTED AMINOGLYCOSIDE PHOSPHOTRANSFERASE)	4kop	SINGLE-STRANDED DNA-BINDING PROTEIN WHY2, MITOCHONDRIAL (Arabidopsis thaliana)	4 / 7	THR A  95 PHE A 113 LEU A 115 SER A 132	None MPO  A 301 (-4.2A) None None	1.17A	5uxcA-4kopA: undetectable	5uxcA-4kopA: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM0_B_CYZB1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	4n11	GLUTAREDOXIN (Plasmodium falciparum)	5 / 10	LEU A  39 ASP A  96 ILE A  78 PRO A  76 GLY A  87	None None None MPO  A 201 (-3.8A) MPO  A 201 (-3.5A)	1.24A	6dm0B-4n11A: undetectable 6dm0C-4n11A: undetectable	6dm0B-4n11A: 17.82 6dm0C-4n11A: 17.82