SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MOO'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1GXS_A_BEZA601_0 (P-(S)-HYDROXYMANDELONITRILE LYASE CHAINAP-(S)-HYDROXYMANDELONITRILE LYASE CHAINB) |
3k6x | SOLUTE-BINDINGPROTEIN MA_0280 (Methanosarcinaacetivorans) | 4 / 7 | GLY A 164PRO A 162SER A 156ALA A 48 | NoneMOO A 500 (-3.3A)NoneMOO A 500 (-3.2A) | 0.97A | 1gxsA-3k6xA:undetectable1gxsB-3k6xA:undetectable | 1gxsA-3k6xA:22.071gxsB-3k6xA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1JO4_A_DVAA6_0 (GRAMICIDIN C) |
3gzg | MOLYBDATE-BINDINGPERIPLASMIC PROTEIN PERMEASE (Xanthomonascitri) | 3 / 3 | ALA A 121VAL A 123TRP A 62 | SO4 A1403 (-3.9A)MOO A1300 (-4.8A)None | 0.91A | 1jo4A-3gzgA:undetectable | 1jo4A-3gzgA:4.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1JO4_B_DVAB6_0 (GRAMICIDIN C) |
3gzg | MOLYBDATE-BINDINGPERIPLASMIC PROTEIN PERMEASE (Xanthomonascitri) | 3 / 3 | ALA A 121VAL A 123TRP A 62 | SO4 A1403 (-3.9A)MOO A1300 (-4.8A)None | 0.91A | 1jo4B-3gzgA:undetectable | 1jo4B-3gzgA:4.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3JB1_A_SAMA1101_0 (STRUCTURAL PROTEINVP3) |
3k6x | SOLUTE-BINDINGPROTEIN MA_0280 (Methanosarcinaacetivorans) | 5 / 12 | GLY A 77ASP A 161PRO A 162ALA A 163ALA A 75 | MOO A 500 (-3.7A)MOO A 500 (-2.7A)MOO A 500 (-3.3A)MOO A 500 (-3.3A)SO4 A 504 (-3.5A) | 0.86A | 3jb1A-3k6xA:undetectable | 3jb1A-3k6xA:14.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3SUE_D_SUED1201_1 (NS3 PROTEASE, NS4APROTEIN) |
3k6x | SOLUTE-BINDINGPROTEIN MA_0280 (Methanosarcinaacetivorans) | 5 / 12 | GLY A 49ASP A 161SER A 81ALA A 79SER A 105 | MOO A 500 (-3.5A)MOO A 500 (-2.7A)NoneNoneNone | 1.21A | 3sueD-3k6xA:undetectable | 3sueD-3k6xA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RN6_A_15UA301_1 (THROMBIN HEAVY CHAIN) |
3k6x | SOLUTE-BINDINGPROTEIN MA_0280 (Methanosarcinaacetivorans) | 5 / 10 | TYR A 165LEU A 102LEU A 51ALA A 48GLY A 295 | NoneNoneNoneMOO A 500 (-3.2A)None | 1.25A | 4rn6A-3k6xA:undetectable | 4rn6A-3k6xA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N5D_B_SAMB303_0 (METHYLTRANSFERASE) |
3k6x | SOLUTE-BINDINGPROTEIN MA_0280 (Methanosarcinaacetivorans) | 5 / 12 | LEU A 173ALA A 174TYR A 143ALA A 163TYR A 245 | NoneNoneNoneMOO A 500 (-3.3A)MOO A 500 (-4.7A) | 1.08A | 5n5dB-3k6xA:undetectable | 5n5dB-3k6xA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GBF_A_ACTA507_0 (MOLYBDOPTERINBIOSYNTHESIS PROTEINCNX1) |
6gbc | MOLYBDOPTERINBIOSYNTHESIS PROTEINCNX1 (Arabidopsisthaliana) | 3 / 3 | LYS A 294SER A 328SER A 400 | NoneMOO A 507 (-2.7A)MOO A 507 (-2.6A) | 0.49A | 6gbfA-6gbcA:53.4 | 6gbfA-6gbcA:undetectable |