SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MNN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE
(Hevea
brasiliensis) 		5 / 10 ASP A  37
TRP A  19
GLY A  82
TYR A  57
SER A  80
 None
None
None
None
MNN  A 300 (-2.5A)
 1.20A 1w76B-1yb6A:
9.9		 1w76B-1yb6A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE
(Hevea
brasiliensis) 		4 / 6 LEU A 148
SER A  80
ILE A 209
HIS A 235
 MNN  A 300 (-4.3A)
MNN  A 300 (-2.5A)
MNN  A 300 (-4.4A)
MNN  A 300 (-4.2A)
 0.89A 1yajF-1yb6A:
9.3		 1yajF-1yb6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE
(Hevea
brasiliensis) 		5 / 12 LEU A  84
VAL A 118
LEU A 121
ILE A 209
LEU A 152
 None
None
None
MNN  A 300 (-4.4A)
None
 1.03A 3w67D-1yb6A:
undetectable		 3w67D-1yb6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE
(Hevea
brasiliensis) 		3 / 3 PHE A 189
THR A  11
LEU A 183
 None
MNN  A 300 (-2.6A)
None
 0.74A 4qztA-1yb6A:
undetectable		 4qztA-1yb6A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE
(Hevea
brasiliensis) 		5 / 12 GLU A 155
TRP A 128
CYH A  81
THR A  11
LEU A 148
 None
MNN  A 300 (-3.8A)
MNN  A 300 ( 3.7A)
MNN  A 300 (-2.6A)
MNN  A 300 (-4.3A)
 0.90A 5fhzD-1yb6A:
2.8		 5fhzD-1yb6A:
17.79