SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MN3'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 LEU A 171
ASP A  77
LEU A  73
LEU A  76
 None
MN3  A1001 (-2.2A)
None
None
 1.07A 1e7cA-3mjoA:
undetectable		 1e7cA-3mjoA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 105
HIS A 104
GLU A  68
HIS A 205
ALA A  98
 None
MN3  A 316 (-3.3A)
MN3  A 316 ( 2.4A)
FE  A 317 (-3.4A)
None
 1.18A 1r55A-3ee4A:
undetectable		 1r55A-3ee4A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLU A 101
HIS A 104
GLU A 167
ILE A 198
GLU A 202
 FE  A 317 (-2.5A)
MN3  A 316 (-3.3A)
FE  A 317 ( 3.0A)
None
FE  A 317 ( 2.6A)
 0.70A 1rnrA-3ee4A:
26.5		 1rnrA-3ee4A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
PHE A 176
ILE A 198
GLU A 202
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
MN3  A1002 (-2.6A)
 0.85A 1rnrA-3mjoA:
31.4		 1rnrA-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
None
 0.70A 1rnrA-3mjoA:
31.4		 1rnrA-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 101
HIS A 104
GLU A 167
ILE A 198
GLU A 202
 FE  A 317 (-2.5A)
MN3  A 316 (-3.3A)
FE  A 317 ( 3.0A)
None
FE  A 317 ( 2.6A)
 0.68A 1rnrB-3ee4A:
26.3		 1rnrB-3ee4A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
PHE A 176
ILE A 198
GLU A 202
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
MN3  A1002 (-2.6A)
 0.79A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
 MN3  A1001 (-2.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
MN3  A1002 (-2.9A)
None
None
None
 0.64A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 GLU A 108
HIS A 111
TYR A 115
LEU A 167
GLU A 168
PHE A 176
ILE A 198
GLU A 202
 MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
None
MN3  A1002 (-2.9A)
None
None
MN3  A1002 (-2.6A)
 0.81A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 12 GLU A 108
HIS A 111
TYR A 115
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
 MN3  A1002 ( 2.4A)
MN3  A1001 (-3.2A)
None
None
MN3  A1002 (-2.9A)
None
None
None
 0.64A 1rnrB-3mjoA:
31.8		 1rnrB-3mjoA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3mds MANGANESE SUPEROXIDE
DISMUTASE
(Thermus
thermophilus) 		5 / 12 ILE A 165
ALA A 133
GLY A 131
SER A 130
HIS A  83
 None
None
None
None
MN3  A 204 (-3.3A)
 1.17A 2a58D-3mdsA:
undetectable
2a58E-3mdsA:
undetectable		 2a58D-3mdsA:
23.04
2a58E-3mdsA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 4br6 SUPEROXIDE DISMUTASE
(Chaetomium
thermophilum) 		6 / 12 SER A 124
GLN A 146
LEU A  81
HIS A  74
ILE A  22
ALA A 165
 None
None
None
MN3  A 301 (-3.5A)
None
None
 1.17A 2bxcA-4br6A:
undetectable		 2bxcA-4br6A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 ASP A  74
THR A 105
HIS A 104
GLU A  68
HIS A 205
 None
None
MN3  A 316 (-3.3A)
MN3  A 316 ( 2.4A)
FE  A 317 (-3.4A)
 1.49A 2jihA-3ee4A:
undetectable		 2jihA-3ee4A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1o9i MANGANESE CATALASE
(Lactobacillus
plantarum) 		5 / 12 GLY A  38
GLY A  63
PHE A 185
HIS A 181
HIS A  69
 None
None
None
MN3  A 268 ( 3.2A)
MN3  A 267 ( 3.3A)
 1.24A 2y7kC-1o9iA:
undetectable		 2y7kC-1o9iA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 GLU A 202
GLU A 101
TYR A 175
GLU A  68
 FE  A 317 ( 2.6A)
FE  A 317 (-2.5A)
None
MN3  A 316 ( 2.4A)
 1.25A 2zt7A-3ee4A:
undetectable		 2zt7A-3ee4A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 4br6 SUPEROXIDE DISMUTASE
(Chaetomium
thermophilum) 		3 / 3 GLU A  79
HIS A  74
HIS A  71
 None
MN3  A 301 (-3.5A)
None
 0.89A 3co4A-4br6A:
undetectable		 3co4A-4br6A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 3l57 MOBILIZATION PROTEIN
TRAI
(Escherichia
coli) 		4 / 8 VAL A 117
HIS A 162
THR A 161
VAL A  16
 None
MN3  A 300 ( 3.3A)
None
None
 0.69A 3fhxB-3l57A:
undetectable		 3fhxB-3l57A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IT4_C_BEZC503_0
(ARGININE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
ARGJ ALPHA CHAIN)		 1o9i MANGANESE CATALASE
(Lactobacillus
plantarum) 		4 / 4 ARG A 177
GLN A 184
LEU A  58
HIS A 181
 None
None
None
MN3  A 268 ( 3.2A)
 1.28A 3it4C-1o9iA:
0.0		 3it4C-1o9iA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1o9i MANGANESE CATALASE
(Lactobacillus
plantarum) 		4 / 5 ARG A 147
LEU A  29
SER A  28
MET A  67
 MN3  A 268 (-4.3A)
None
None
None
 1.04A 4e1gA-1o9iA:
undetectable		 4e1gA-1o9iA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 1o9i MANGANESE CATALASE
(Lactobacillus
plantarum) 		3 / 3 GLY A  31
GLU A  35
THR A  36
 None
MN3  A 267 (-2.6A)
None
 0.48A 4kouA-1o9iA:
undetectable		 4kouA-1o9iA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_A_ADNA403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 ASP A  77
PHE A 172
ASP A 201
ILE A 199
ILE A 195
 MN3  A1001 (-2.2A)
MN3  A1001 ( 4.5A)
None
None
None
 1.23A 4ktvA-3mjoA:
undetectable
4ktvB-3mjoA:
undetectable		 4ktvA-3mjoA:
20.35
4ktvB-3mjoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 ASP A  77
PHE A 172
ASP A 201
ILE A 199
ILE A 195
 MN3  A1001 (-2.2A)
MN3  A1001 ( 4.5A)
None
None
None
 1.28A 4ktvC-3mjoA:
undetectable
4ktvD-3mjoA:
undetectable		 4ktvC-3mjoA:
20.35
4ktvD-3mjoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3l57 MOBILIZATION PROTEIN
TRAI
(Escherichia
coli) 		5 / 12 TYR A  83
HIS A 149
HIS A 162
PHE A 164
GLY A  17
 None
MN3  A 300 (-3.2A)
MN3  A 300 ( 3.3A)
None
None
 1.07A 4qa0A-3l57A:
undetectable		 4qa0A-3l57A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3l57 MOBILIZATION PROTEIN
TRAI
(Escherichia
coli) 		5 / 11 TYR A  83
HIS A 149
HIS A 162
PHE A 164
GLY A  17
 None
MN3  A 300 (-3.2A)
MN3  A 300 ( 3.3A)
None
None
 1.07A 4qa0B-3l57A:
undetectable		 4qa0B-3l57A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3l57 MOBILIZATION PROTEIN
TRAI
(Escherichia
coli) 		5 / 12 TYR A  83
HIS A 149
HIS A 162
PHE A 164
GLY A  17
 None
MN3  A 300 (-3.2A)
MN3  A 300 ( 3.3A)
None
None
 1.06A 4qa2A-3l57A:
undetectable		 4qa2A-3l57A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3l57 MOBILIZATION PROTEIN
TRAI
(Escherichia
coli) 		5 / 12 TYR A  83
HIS A 149
HIS A 162
PHE A 164
GLY A  17
 None
MN3  A 300 (-3.2A)
MN3  A 300 ( 3.3A)
None
None
 1.08A 4qa2B-3l57A:
undetectable		 4qa2B-3l57A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 PHE A 176
ILE A 199
HIS A 111
GLU A 108
ASP A  77
 None
None
MN3  A1001 (-3.2A)
MN3  A1002 ( 2.4A)
MN3  A1001 (-2.2A)
 1.34A 4r88A-3mjoA:
undetectable		 4r88A-3mjoA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 1o9i MANGANESE CATALASE
(Lactobacillus
plantarum) 		4 / 5 GLU A 148
ALA A 151
GLU A 178
GLU A  66
 MN3  A 268 ( 2.7A)
None
None
MN3  A 267 (-2.6A)
 1.09A 5dwkC-1o9iA:
2.9		 5dwkC-1o9iA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		4 / 5 TYR A 173
GLU A 168
GLY A 206
SER A 203
 None
MN3  A1002 (-2.9A)
None
None
 1.19A 5jhdJ-3mjoA:
undetectable		 5jhdJ-3mjoA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 9 LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 198
 None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.71A 6ebpA-3mjoA:
41.1		 6ebpA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		6 / 9 LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 198
 None
None
MN3  A1001 (-2.2A)
None
None
None
 0.71A 6ebpA-3mjoA:
41.1		 6ebpA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
 0.67A 6ebpB-3mjoA:
40.8		 6ebpB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
 0.67A 6ebpB-3mjoA:
40.8		 6ebpB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.69A 6ebpC-3mjoA:
41.0		 6ebpC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
 0.56A 6ebpD-3mjoA:
40.8		 6ebpD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.65A 6ebzA-3mjoA:
41.1		 6ebzA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.65A 6ebzA-3mjoA:
41.1		 6ebzA-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.66A 6ebzB-3mjoA:
41.3		 6ebzB-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		7 / 11 PHE A  70
LEU A  73
SER A 114
ILE A 118
PHE A 119
PHE A 172
ILE A 198
 None
None
None
None
None
MN3  A1001 ( 4.5A)
None
 1.42A 6ebzC-3mjoA:
41.4		 6ebzC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
None
 0.64A 6ebzC-3mjoA:
41.4		 6ebzC-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
 0.68A 6ebzD-3mjoA:
41.0		 6ebzD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 LEU A  73
ASP A  77
PHE A 176
ILE A 195
ILE A 198
 None
MN3  A1001 (-2.2A)
None
None
None
 0.85A 6gp2A-3mjoA:
40.6		 6gp2A-3mjoA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 LEU A  73
ASP A  77
PHE A 176
ILE A 195
ILE A 198
 None
MN3  A1001 (-2.2A)
None
None
None
 0.87A 6gp2B-3mjoA:
40.5		 6gp2B-3mjoA:
18.49