SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MMC'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KGL_A_RTLA175_1 (CELLULAR RETINOL-BINDING PROTEIN TYPE I)	5g5n	LH3 HEXON-INTERLACING CAPSID PROTEIN (Snake atadenovirus A)	4 / 7	LEU A 266 THR A 120 MET A 123 TRP A 126	None GOL A1374 (-3.1A) GOL A1374 ( 4.9A) MMC A1379 ( 3.4A)	1.24A	1kglA-5g5nA: undetectable	1kglA-5g5nA: 16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IYF_B_ERYB1399_0 (OLEANDOMYCIN GLYCOSYLTRANSFERASE)	2d2n	GIANT HEMOGLOBIN, A2(A5) GLOBIN CHAIN (Oligobrachia mashikoi)	5 / 12	TRP B 32 ILE B 140 LEU B 86 SER B 92 ASP B 71	None None MMC B1500 ( 4.5A) None None	1.26A	2iyfB-2d2nB: undetectable	2iyfB-2d2nB: 15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI507_0 (RNA POLYMERASE 3D-POL)	4ct3	ORF30/ORF32 (Staphylococcus virus K)	3 / 3	LYS A 94 PRO A 95 SER A 96	MMC A1172 ( 4.3A) None None	0.48A	4k50I-4ct3A: undetectable	4k50I-4ct3A: 16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6I_A_8PRA509_1 (ENVELOPE GLYCOPROTEIN,GP,GP1 ENVELOPE GLYCOPROTEIN)	1in0	YAJQ PROTEIN (Haemophilus influenzae)	5 / 12	VAL A 19 LEU A 65 GLU A 20 ALA A 18 LEU A 79	None MMC A 201 (-4.4A) None MMC A 201 ( 3.7A) HG A 202 ( 4.3A)	1.15A	6f6iA-1in0A: undetectable 6f6iB-1in0A: undetectable	6f6iA-1in0A: 18.24 6f6iB-1in0A: 21.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KGL_A_RTLA175_1","CELLULAR RETINOL-BINDING PROTEIN TYPE I","5g5n","LH3 HEXON-INTERLACING CAPSID PROTEIN","Snake atadenovirus A",4,"LEU A 266;THR A 120;MET A 123;TRP A 126","None;GOL A1374 (-3.1A);GOL A1374 ( 4.9A);MMC A1379 ( 3.4A)","1.24A","1kglA-5g5nA:undetectable",null],["2IYF_B_ERYB1399_0","OLEANDOMYCIN GLYCOSYLTRANSFERASE","2d2n","GIANT HEMOGLOBIN, A2(A5) GLOBIN CHAIN","Oligobrachia mashikoi",5,"TRP B  32;ILE B 140;LEU B  86;SER B  92;ASP B  71","None;None;MMC B1500 ( 4.5A);None;None","1.26A","2iyfB-2d2nB:undetectable","1kglA-5g5nA:16.08"],["4K50_I_ACTI507_0","RNA POLYMERASE 3D-POL","4ct3","ORF30\/ORF32","Staphylococcus virus K",3,"LYS A  94;PRO A  95;SER A  96","MMC A1172 ( 4.3A);None;None","0.48A","4k50I-4ct3A:undetectable","2iyfB-2d2nB:15.27"],["6F6I_A_8PRA509_1","ENVELOPE GLYCOPROTEIN,GP,GP1;ENVELOPE GLYCOPROTEIN","1in0","YAJQ PROTEIN","Haemophilus influenzae",5,"VAL A  19;LEU A  65;GLU A  20;ALA A  18;LEU A  79","None;MMC A 201 (-4.4A);None;MMC A 201 ( 3.7A); HG A 202 ( 4.3A)","1.15A","6f6iA-1in0A:undetectable;6f6iB-1in0A:undetectable","4k50I-4ct3A:16.63"]]