SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MLD'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_G_TRPG81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX (Drosophila melanogaster)	4 / 7	THR X 422 SER X 429 GLY X 472 HIS X 473	None None None MLD  X 201 (-3.9A)	0.91A	1gtnF-2f2lX: undetectable 1gtnG-2f2lX: undetectable	1gtnF-2f2lX: 20.75 1gtnG-2f2lX: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_K_TRPK81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX (Drosophila melanogaster)	4 / 7	THR X 422 SER X 429 GLY X 472 HIS X 473	None None None MLD  X 201 (-3.9A)	0.98A	1gtnJ-2f2lX: undetectable 1gtnK-2f2lX: undetectable	1gtnJ-2f2lX: 20.75 1gtnK-2f2lX: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRL_A_DXTA1211_1 (TETRACYCLINE REPRESSOR PROTEIN CLASS D)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX (Drosophila melanogaster)	5 / 12	HIS X 365 SER X 481 PHE X 438 LEU X 470 ILE X 490	MLD  X 201 (-3.9A) MLD  X 201 (-3.4A) None None None	1.19A	2xrlA-2f2lX: undetectable	2xrlA-2f2lX: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_A_ADNA500_2 (ADENOSYLHOMOCYSTEINA SE)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LC ISOFORM LCA (Drosophila melanogaster)	4 / 5	GLN A 404 THR A 405 GLU X 480 HIS X 473	None MLD  X 201 (-4.1A) None MLD  X 201 (-3.9A)	1.42A	3n58A-2f2lA: undetectable	3n58A-2f2lA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_C_ADNC500_2 (ADENOSYLHOMOCYSTEINA SE)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LC ISOFORM LCA (Drosophila melanogaster)	4 / 5	GLN A 404 THR A 405 GLU X 480 HIS X 473	None MLD  X 201 (-4.1A) None MLD  X 201 (-3.9A)	1.42A	3n58C-2f2lA: undetectable	3n58C-2f2lA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_D_ADND500_2 (ADENOSYLHOMOCYSTEINA SE)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LC ISOFORM LCA (Drosophila melanogaster)	4 / 4	GLN A 404 THR A 405 GLU X 480 HIS X 473	None MLD  X 201 (-4.1A) None MLD  X 201 (-3.9A)	1.46A	3n58D-2f2lA: undetectable	3n58D-2f2lA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OOI_A_SAMA237_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC)	2cb3	PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LE (Drosophila melanogaster)	5 / 12	GLY A 265 ASN A 267 ASN A 318 CYH A 315 LEU A 205	None MLD  A1345 (-3.2A) MLD  A1345 (-3.2A) None MLD  A1345 ( 4.6A)	1.35A	3ooiA-2cb3A: undetectable	3ooiA-2cb3A: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RET_A_SALA201_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX (Drosophila melanogaster)	5 / 10	ALA X 450 VAL X 409 TYR X 399 ILE X 432 ILE X 435	None None MLD  X 201 (-4.6A) None None	1.24A	3retA-2f2lX: undetectable 3retB-2f2lX: undetectable	3retA-2f2lX: 20.11 3retB-2f2lX: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_A_SAMA301_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	4qtf	L,D-TRANSPEPTIDASE LDTB (Mycobacterium tuberculosis)	3 / 3	SER A  65 ASP A  76 ASP A 232	MLD  A 501 (-4.7A) None None	0.87A	4mwzA-4qtfA: undetectable	4mwzA-4qtfA: 18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHZ_A_REAA602_1 (ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3)	2cb3	PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LE (Drosophila melanogaster)	5 / 12	GLY A 253 ARG A 254 ASN A 218 LEU A 243 THR A 209	None MLD  A1345 (-3.0A) None None None	1.42A	5fhzA-2cb3A: undetectable	5fhzA-2cb3A: 16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UPD_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	2cb3	PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LE (Drosophila melanogaster)	5 / 11	GLY A 265 ASN A 267 ASN A 318 CYH A 315 LEU A 205	None MLD  A1345 (-3.2A) MLD  A1345 (-3.2A) None MLD  A1345 ( 4.6A)	1.35A	5updA-2cb3A: undetectable	5updA-2cb3A: 20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA309_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX (Drosophila melanogaster)	4 / 4	LEU X 486 GLY X 483 SER X 481 SER X 364	None None MLD  X 201 (-3.4A) MLD  X 201 ( 3.9A)	1.33A	5uunA-2f2lX: undetectable	5uunA-2f2lX: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB306_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	2f2l	PEPTIDOGLYCAN RECOGNITION PROTEIN-LC ISOFORM LCX (Drosophila melanogaster)	4 / 4	LEU X 486 GLY X 483 SER X 481 SER X 364	None None MLD  X 201 (-3.4A) MLD  X 201 ( 3.9A)	1.30A	5uunB-2f2lX: undetectable	5uunB-2f2lX: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CEN_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	2cb3	PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LE (Drosophila melanogaster)	5 / 11	GLY A 265 ASN A 267 ASN A 318 CYH A 315 LEU A 205	None MLD  A1345 (-3.2A) MLD  A1345 (-3.2A) None MLD  A1345 ( 4.6A)	1.38A	6cenA-2cb3A: undetectable	6cenA-2cb3A: 21.22