SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MLB'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GVC_B_MMZB501_1 (MONOOXYGENASE)	3alt	LECTIN CEL-IV, C-TYPE (Cucumaria echinata)	3 / 3	ASN A 115 TYR A 129 SER A 111	MLB A 301 (-2.6A) MLB A 301 ( 4.2A) None	0.82A	2gvcB-3altA: undetectable	2gvcB-3altA: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GVC_E_MMZE501_1 (MONOOXYGENASE)	3alt	LECTIN CEL-IV, C-TYPE (Cucumaria echinata)	3 / 3	ASN A 115 TYR A 129 SER A 111	MLB A 301 (-2.6A) MLB A 301 ( 4.2A) None	0.88A	2gvcE-3altA: undetectable	2gvcE-3altA: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_F_377F402_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3alt	LECTIN CEL-IV, C-TYPE (Cucumaria echinata)	4 / 8	ALA A 123 ALA A 135 SER A 130 ALA A 80	None MLB A 301 ( 3.9A) None None	0.80A	4twdF-3altA: undetectable 4twdG-3altA: undetectable 4twdH-3altA: undetectable 4twdI-3altA: undetectable 4twdJ-3altA: undetectable	4twdF-3altA: 17.10 4twdG-3altA: 17.10 4twdH-3altA: 17.10 4twdI-3altA: 17.10 4twdJ-3altA: 17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_F_377F402_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3alt	LECTIN CEL-IV, C-TYPE (Cucumaria echinata)	4 / 8	ALA A 135 SER A 130 ALA A 80 ALA A 123	MLB A 301 ( 3.9A) None None None	0.67A	4twdF-3altA: undetectable 4twdG-3altA: undetectable 4twdH-3altA: undetectable 4twdI-3altA: undetectable 4twdJ-3altA: undetectable	4twdF-3altA: 17.10 4twdG-3altA: 17.10 4twdH-3altA: 17.10 4twdI-3altA: 17.10 4twdJ-3altA: 17.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2GVC_B_MMZB501_1","MONOOXYGENASE","3alt","LECTIN CEL-IV, C-TYPE","Cucumaria echinata",3,"ASN A 115;TYR A 129;SER A 111","MLB A 301 (-2.6A);MLB A 301 ( 4.2A);None","0.82A","2gvcB-3altA:undetectable",null],["2GVC_E_MMZE501_1","MONOOXYGENASE","3alt","LECTIN CEL-IV, C-TYPE","Cucumaria echinata",3,"ASN A 115;TYR A 129;SER A 111","MLB A 301 (-2.6A);MLB A 301 ( 4.2A);None","0.88A","2gvcE-3altA:undetectable","2gvcB-3altA:17.86"],["4TWD_F_377F402_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3alt","LECTIN CEL-IV, C-TYPE","Cucumaria echinata",4,"ALA A 123;ALA A 135;SER A 130;ALA A  80","None;MLB A 301 ( 3.9A);None;None","0.80A","4twdF-3altA:undetectable;4twdG-3altA:undetectable;4twdH-3altA:undetectable;4twdI-3altA:undetectable;4twdJ-3altA:undetectable","2gvcE-3altA:17.86"],["4TWD_F_377F402_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3alt","LECTIN CEL-IV, C-TYPE","Cucumaria echinata",4,"ALA A 135;SER A 130;ALA A  80;ALA A 123","MLB A 301 ( 3.9A);None;None;None","0.67A","4twdF-3altA:undetectable;4twdG-3altA:undetectable;4twdH-3altA:undetectable;4twdI-3altA:undetectable;4twdJ-3altA:undetectable","4twdF-3altA:17.10;4twdG-3altA:17.10;4twdH-3altA:17.10;4twdI-3altA:17.10;4twdJ-3altA:17.10"]]