SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ML1'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 5mxb CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN
(Lupinus
luteus) 		4 / 8 SER A 148
ALA A  33
PHE A 142
GLU A 147
 None
None
ML1  A 222 (-4.3A)
None
 1.06A 1dmiA-5mxbA:
undetectable
1dmiB-5mxbA:
undetectable		 1dmiA-5mxbA:
11.25
1dmiB-5mxbA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 5mxb CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN
(Lupinus
luteus) 		4 / 8 TYR A  65
SER A  39
VAL A  85
HIS A  68
 None
None
None
ML1  A 220 ( 4.8A)
 0.90A 3b9lA-5mxbA:
undetectable		 3b9lA-5mxbA:
8.93