SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MIR'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qpc CUTINASE
(Fusarium
solani) 		5 / 9 GLY A 122
ALA A 127
THR A  90
SER A 129
ALA A 128
 MIR  A 120 ( 4.0A)
None
None
None
None
 1.49A 1gtnQ-3qpcA:
undetectable
1gtnR-3qpcA:
undetectable		 1gtnQ-3qpcA:
17.77
1gtnR-3qpcA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3qpc CUTINASE
(Fusarium
solani) 		5 / 12 ALA A 126
GLY A 122
ALA A 116
SER A 129
PHE A 102
 None
MIR  A 120 ( 4.0A)
None
None
None
 1.14A 1ve3B-3qpcA:
2.1		 1ve3B-3qpcA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3hp4 GDSL-ESTERASE
(Pseudoalteromona
s
sp.
643A) 		5 / 11 GLN A 167
LEU A  12
ALA A 166
MET A 155
ASP A 147
 None
MIR  A  11 ( 4.2A)
None
None
None
 1.28A 2c12F-3hp4A:
undetectable		 2c12F-3hp4A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 3qpc CUTINASE
(Fusarium
solani) 		4 / 4 ALA A 123
VAL A 169
PHE A 147
THR A 144
 MIR  A 120 ( 2.9A)
None
None
None
 1.48A 2pkkA-3qpcA:
4.9		 2pkkA-3qpcA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 3qpc CUTINASE
(Fusarium
solani) 		4 / 8 PHE A 147
HIS A 188
GLY A 148
GLY A  49
 None
MIR  A 120 ( 3.7A)
MIR  A 120 ( 4.2A)
None
 0.96A 3v3nB-3qpcA:
undetectable		 3v3nB-3qpcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 3qpc CUTINASE
(Fusarium
solani) 		4 / 8 PHE A 147
HIS A 188
GLY A 148
GLY A  49
 None
MIR  A 120 ( 3.7A)
MIR  A 120 ( 4.2A)
None
 0.97A 3v3nC-3qpcA:
undetectable		 3v3nC-3qpcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3qpc CUTINASE
(Fusarium
solani) 		5 / 12 ALA A 195
GLN A 121
PHE A 147
GLY A  41
SER A  42
 None
None
None
MIR  A 120 ( 3.3A)
MIR  A 120 ( 2.6A)
 1.30A 5hfjF-3qpcA:
2.3		 5hfjF-3qpcA:
21.57