SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MHF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 2j4d CRYPTOCHROME DASH
(Arabidopsis
thaliana) 		5 / 12 LEU A  50
LEU A 102
LEU A  78
GLU A 149
LEU A  74
 None
None
None
MHF  A1499 (-2.8A)
None
 1.08A 1sn5B-2j4dA:
undetectable
1sn5D-2j4dA:
undetectable		 1sn5B-2j4dA:
14.34
1sn5D-2j4dA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 2j4d CRYPTOCHROME DASH
(Arabidopsis
thaliana) 		5 / 12 LEU A  78
GLU A 149
LEU A  74
LEU A  50
LEU A 102
 None
MHF  A1499 (-2.8A)
None
None
None
 1.10A 1sn5B-2j4dA:
undetectable
1sn5D-2j4dA:
undetectable		 1sn5B-2j4dA:
14.34
1sn5D-2j4dA:
14.34