SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MGM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.95A 1c9sN-1tnuB:
undetectable
1c9sO-1tnuB:
undetectable		 1c9sN-1tnuB:
12.68
1c9sO-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1c9sP-1tnuB:
0.0
1c9sQ-1tnuB:
0.0		 1c9sP-1tnuB:
12.68
1c9sQ-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 9 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.98A 1c9sQ-1tnuB:
0.0
1c9sR-1tnuB:
undetectable		 1c9sQ-1tnuB:
12.68
1c9sR-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.97A 1c9sL-1tnuB:
undetectable
1c9sV-1tnuB:
undetectable		 1c9sL-1tnuB:
12.68
1c9sV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 8 TYR B 272
VAL B 276
GLY B 221
GLY B 220
 None
None
MGM  B 379 ( 3.9A)
None
 0.84A 1ekjE-1tnuB:
undetectable
1ekjF-1tnuB:
undetectable		 1ekjE-1tnuB:
20.78
1ekjF-1tnuB:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 9 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.98A 1gtfD-1tnuB:
0.0
1gtfE-1tnuB:
0.0		 1gtfD-1tnuB:
12.68
1gtfE-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 1gtfJ-1tnuB:
undetectable
1gtfK-1tnuB:
undetectable		 1gtfJ-1tnuB:
12.68
1gtfK-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1gtfQ-1tnuB:
0.0
1gtfR-1tnuB:
undetectable		 1gtfQ-1tnuB:
12.68
1gtfR-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 9 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1gtfR-1tnuB:
undetectable
1gtfS-1tnuB:
undetectable		 1gtfR-1tnuB:
12.68
1gtfS-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1gtfS-1tnuB:
undetectable
1gtfT-1tnuB:
undetectable		 1gtfS-1tnuB:
12.68
1gtfT-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.97A 1gtnT-1tnuB:
undetectable
1gtnU-1tnuB:
undetectable		 1gtnT-1tnuB:
12.68
1gtnU-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.95A 1gtnL-1tnuB:
undetectable
1gtnV-1tnuB:
undetectable		 1gtnL-1tnuB:
12.68
1gtnV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 CYH B 271
THR B 127
SER B  56
VAL B 346
ALA B 319
 ZN  B 378 (-2.2A)
MGM  B 379 ( 4.6A)
None
None
None
 1.23A 1nw5A-1tnuB:
undetectable		 1nw5A-1tnuB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 1.02A 1utdE-1tnuB:
undetectable
1utdF-1tnuB:
0.0		 1utdE-1tnuB:
12.68
1utdF-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 1.03A 1utdH-1tnuB:
undetectable
1utdI-1tnuB:
0.0		 1utdH-1tnuB:
12.68
1utdI-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.95A 1utdL-1tnuB:
undetectable
1utdM-1tnuB:
undetectable		 1utdL-1tnuB:
12.68
1utdM-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.99A 1utdO-1tnuB:
undetectable
1utdP-1tnuB:
undetectable		 1utdO-1tnuB:
12.68
1utdP-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1utdP-1tnuB:
undetectable
1utdQ-1tnuB:
undetectable		 1utdP-1tnuB:
12.68
1utdQ-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.98A 1utdS-1tnuB:
undetectable
1utdT-1tnuB:
undetectable		 1utdS-1tnuB:
12.68
1utdT-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.94A 1utdU-1tnuB:
undetectable
1utdV-1tnuB:
undetectable		 1utdU-1tnuB:
12.68
1utdV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.97A 1utdL-1tnuB:
undetectable
1utdV-1tnuB:
undetectable		 1utdL-1tnuB:
12.68
1utdV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 CYH B 225
ALA B 278
PHE B 274
LEU B  48
PHE B  52
 MGM  B 379 ( 3.9A)
None
None
None
None
 1.43A 4iaqA-1tnuB:
undetectable		 4iaqA-1tnuB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.04A 5eevA-1tnuB:
undetectable
5eevB-1tnuB:
undetectable		 5eevA-1tnuB:
12.68
5eevB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.04A 5eewA-1tnuB:
undetectable
5eewB-1tnuB:
undetectable		 5eewA-1tnuB:
12.68
5eewB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.04A 5eexA-1tnuB:
undetectable
5eexB-1tnuB:
undetectable		 5eexA-1tnuB:
12.68
5eexB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5eeyA-1tnuB:
undetectable
5eeyB-1tnuB:
undetectable		 5eeyA-1tnuB:
12.68
5eeyB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5eezA-1tnuB:
0.0
5eezB-1tnuB:
undetectable		 5eezA-1tnuB:
12.68
5eezB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef0A-1tnuB:
undetectable
5ef0B-1tnuB:
undetectable		 5ef0A-1tnuB:
12.68
5ef0B-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef1A-1tnuB:
undetectable
5ef1B-1tnuB:
undetectable		 5ef1A-1tnuB:
12.68
5ef1B-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef2A-1tnuB:
undetectable
5ef2B-1tnuB:
undetectable		 5ef2A-1tnuB:
12.68
5ef2B-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef3A-1tnuB:
undetectable
5ef3B-1tnuB:
undetectable		 5ef3A-1tnuB:
12.68
5ef3B-1tnuB:
12.68