SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MG7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HO5_A_ADNA1604_1 (5'-NUCLEOTIDASE)	4nv0	7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE (Drosophila melanogaster)	5 / 11	GLY A 125 PHE A 75 ASN A 79 GLY A 208 PHE A 78	None MG7 A 403 (-3.6A) MG7 A 403 ( 4.7A) None None	1.27A	1ho5A-4nv0A: undetectable	1ho5A-4nv0A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HO5_B_ADNB2604_1 (5'-NUCLEOTIDASE)	4nv0	7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE (Drosophila melanogaster)	5 / 10	GLY A 125 PHE A 75 ASN A 79 GLY A 208 PHE A 78	None MG7 A 403 (-3.6A) MG7 A 403 ( 4.7A) None None	1.19A	1ho5B-4nv0A: undetectable	1ho5B-4nv0A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VN1_A_FK5A501_2 (70 KDA PEPTIDYLPROLYL ISOMERASE)	4nv0	7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE (Drosophila melanogaster)	4 / 6	LEU A 206 SER A 74 PHE A 75 ASP A 57	None MG7 A 403 ( 4.2A) MG7 A 403 (-3.6A) MG7 A 403 (-3.9A)	1.28A	2vn1B-4nv0A: undetectable	2vn1B-4nv0A: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BRF_A_SORA1_0 (LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A)	4nv0	7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE (Drosophila melanogaster)	3 / 3	GLY A 173 ASP A 57 SER A 73	MG7 A 403 (-3.5A) MG7 A 403 (-3.9A) MG7 A 403 ( 4.6A)	0.63A	3brfA-4nv0A: undetectable	3brfA-4nv0A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_A_SAMA1281_1 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	4nv0	7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE (Drosophila melanogaster)	4 / 6	SER A 171 GLU A 103 ASP A 270 ASP A 57	MGF A 404 (-2.7A) MG7 A 403 (-2.8A) None MG7 A 403 (-3.9A)	1.08A	4blvA-4nv0A: 2.4	4blvA-4nv0A: 20.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HO5_A_ADNA1604_1","5'-NUCLEOTIDASE","4nv0","7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE","Drosophila melanogaster",5,"GLY A 125;PHE A  75;ASN A  79;GLY A 208;PHE A  78","None;MG7 A 403 (-3.6A);MG7 A 403 ( 4.7A);None;None","1.27A","1ho5A-4nv0A:undetectable",null],["1HO5_B_ADNB2604_1","5'-NUCLEOTIDASE","4nv0","7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE","Drosophila melanogaster",5,"GLY A 125;PHE A  75;ASN A  79;GLY A 208;PHE A  78","None;MG7 A 403 (-3.6A);MG7 A 403 ( 4.7A);None;None","1.19A","1ho5B-4nv0A:undetectable","1ho5A-4nv0A:21.43"],["2VN1_A_FK5A501_2","70 KDA PEPTIDYLPROLYL ISOMERASE;70 KDA PEPTIDYLPROLYL ISOMERASE","4nv0","7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE","Drosophila melanogaster",4,"LEU A 206;SER A  74;PHE A  75;ASP A  57","None;MG7 A 403 ( 4.2A);MG7 A 403 (-3.6A);MG7 A 403 (-3.9A)","1.28A","2vn1B-4nv0A:undetectable","1ho5B-4nv0A:21.43"],["3BRF_A_SORA1_0","LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A","4nv0","7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE","Drosophila melanogaster",3,"GLY A 173;ASP A  57;SER A  73","MG7 A 403 (-3.5A);MG7 A 403 (-3.9A);MG7 A 403 ( 4.6A)","0.63A","3brfA-4nv0A:undetectable","2vn1B-4nv0A:18.10"],["4BLV_A_SAMA1281_1","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","4nv0","7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE","Drosophila melanogaster",4,"SER A 171;GLU A 103;ASP A 270;ASP A  57","MGF A 404 (-2.7A);MG7 A 403 (-2.8A);None;MG7 A 403 (-3.9A)","1.08A","4blvA-4nv0A:2.4","3brfA-4nv0A:22.56"]]