SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MCA'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KT7_A_RTLA184_0 (PLASMA RETINOL-BINDING PROTEIN)	3nyq	MALONYL-COA LIGASE (Streptomyces coelicolor)	5 / 11	LEU A 193 LEU A 191 ALA A  67 VAL A 188 LEU A 160	None None None MCA  A 486 ( 4.1A) None	0.95A	1kt7A-3nyqA: undetectable	1kt7A-3nyqA: 17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_B_SAMB600_0 (PCZA361.24)	3nyq	MALONYL-COA LIGASE (Streptomyces coelicolor)	5 / 12	GLY A 209 LEU A 183 SER A 212 GLY A 215 GLU A 219	None MCA  A 486 ( 4.3A) None None None	1.04A	3g2oB-3nyqA: undetectable	3g2oB-3nyqA: 25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYE_B_YTZB902_1 (DIHYDROPTEROATE SYNTHASE)	1on9	METHYLMALONYL-COA CARBOXYLTRANSFERASE 12S SUBUNIT (Propionibacteriu m freudenreichii)	3 / 3	PHE A 105 LYS A  38 SER A  41	MCA  A4001 (-4.4A) None None	1.36A	3tyeB-1on9A: undetectable	3tyeB-1on9A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HFP_B_15UB402_1 (PROTHROMBIN)	3nyq	MALONYL-COA LIGASE (Streptomyces coelicolor)	5 / 12	HIS A 187 ALA A 455 ILE A 389 GLU A  86 GLY A 145	MCA  A 486 ( 4.2A) CL  A 498 ( 3.7A) None None None	1.12A	4hfpB-3nyqA: undetectable	4hfpB-3nyqA: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE1_A_X2NA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3nyq	MALONYL-COA LIGASE (Streptomyces coelicolor)	5 / 12	GLY A 285 MET A 286 PHE A  24 GLY A  62 LEU A 196	MCA  A 486 ( 3.7A) AMP  A 487 ( 3.8A) CL  A 497 (-4.7A) None None	1.29A	4ze1A-3nyqA: undetectable	4ze1A-3nyqA: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DBY_A_ACTA617_0 (SERUM ALBUMIN)	3nyq	MALONYL-COA LIGASE (Streptomyces coelicolor)	3 / 3	TRP A 171 ARG A 283 LEU A 179	None MCA  A 486 ( 3.0A) None	0.85A	5dbyA-3nyqA: undetectable	5dbyA-3nyqA: 22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_B_PAUB601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	1on9	METHYLMALONYL-COA CARBOXYLTRANSFERASE 12S SUBUNIT (Propionibacteriu m freudenreichii)	4 / 7	GLU A 147 GLY A  85 SER A 111 GLY A 109	None None MCA  A4001 (-3.7A) MCA  A4001 (-3.0A)	0.80A	5e26A-1on9A: undetectable 5e26B-1on9A: undetectable	5e26A-1on9A: 22.46 5e26B-1on9A: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_C_PAUC602_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	1on9	METHYLMALONYL-COA CARBOXYLTRANSFERASE 12S SUBUNIT (Propionibacteriu m freudenreichii)	4 / 7	GLU A 147 GLY A  85 SER A 111 GLY A 109	None None MCA  A4001 (-3.7A) MCA  A4001 (-3.0A)	0.81A	5e26C-1on9A: undetectable 5e26D-1on9A: undetectable	5e26C-1on9A: 22.46 5e26D-1on9A: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IMS_A_ACTA708_0 (ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL)	1on9	METHYLMALONYL-COA CARBOXYLTRANSFERASE 12S SUBUNIT (Propionibacteriu m freudenreichii)	3 / 3	GLY A 142 GLY A 141 GLN A 103	MCA  A4001 ( 4.1A) MCA  A4001 (-3.4A) None	0.47A	5imsA-1on9A: 2.1	5imsA-1on9A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPR_A_PAUA404_0 (PANTOTHENATE KINASE 3)	1on9	METHYLMALONYL-COA CARBOXYLTRANSFERASE 12S SUBUNIT (Propionibacteriu m freudenreichii)	4 / 5	GLU A 147 GLY A  85 SER A 111 GLY A 109	None None MCA  A4001 (-3.7A) MCA  A4001 (-3.0A)	0.89A	5kprA-1on9A: undetectable	5kprA-1on9A: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA501_2 (CYTOCHROME P450 2C9)	3nyq	MALONYL-COA LIGASE (Streptomyces coelicolor)	4 / 4	PHE A 228 LEU A 160 LEU A 167 VAL A 188	None None None MCA  A 486 ( 4.1A)	0.96A	5xxiA-3nyqA: undetectable	5xxiA-3nyqA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DGX_A_017A101_2 (PROTEASE)	1on9	METHYLMALONYL-COA CARBOXYLTRANSFERASE 12S SUBUNIT (Propionibacteriu m freudenreichii)	3 / 3	GLY A 141 ASP A 139 ILE A 175	MCA  A4001 (-3.4A) None None	0.57A	6dgxB-1on9A: undetectable	6dgxB-1on9A: 8.80