SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MC5'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 GLY A 284
CYH A 285
SER A 289
HIS A 323
TYR A 327
MET A 348
LEU A 353
MET A 364
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 ( 4.0A)
MC5  A   1 (-4.7A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.48A 1fm6D-3b0qA:
39.8
1fm6D-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 GLY A 284
LEU A 356
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 ( 4.5A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.37A 1fm6D-3b0qA:
39.8
1fm6D-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
4 / 4 ILE A 281
LEU A 330
VAL A 339
ILE A 341
MC5  A   1 ( 4.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
0.21A 1fm6D-3b0qA:
39.8
1fm6D-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 ILE A 281
PHE A 282
GLY A 284
CYH A 285
LEU A 452
MC5  A   1 ( 4.8A)
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
1.36A 1fm6X-3b0qA:
39.4
1fm6X-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 ILE A 281
PHE A 282
GLY A 284
CYH A 285
SER A 289
HIS A 323
TYR A 327
MET A 364
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 ( 4.8A)
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.68A 1fm6X-3b0qA:
39.4
1fm6X-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 PHE A 282
GLY A 284
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
LEU A 353
MET A 364
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.39A 1zgyA-3b0qA:
40.1
1zgyA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 PHE A 282
GLY A 284
LEU A 356
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.44A 1zgyA-3b0qA:
40.1
1zgyA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 5 ILE A 281
ILE A 326
ILE A 341
MET A 348
LEU A 453
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-4.2A)
0.37A 1zgyA-3b0qA:
40.1
1zgyA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 GLY A 284
CYH A 285
GLN A 286
SER A 289
HIS A 323
TYR A 327
LEU A 330
MET A 348
MET A 364
HIS A 449
TYR A 473
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.56A 2prgA-3b0qA:
40.0
2prgA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 PHE A 282
GLY A 284
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
MET A 348
MET A 364
HIS A 449
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.55A 2prgA-3b0qA:
40.0
2prgA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
3 / 3 ILE A 281
ILE A 341
LEU A 453
MC5  A   1 ( 4.8A)
MC5  A   1 (-4.5A)
MC5  A   1 (-4.2A)
0.48A 2prgA-3b0qA:
40.0
2prgA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 PHE A 282
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
VAL A 339
MET A 364
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.45A 2prgB-3b0qA:
38.8
2prgB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 PHE A 282
CYH A 285
HIS A 323
TYR A 327
LEU A 330
ILE A 341
MET A 348
MET A 364
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.48A 2xkwA-3b0qA:
42.6
2xkwA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 PHE A 282
SER A 289
HIS A 323
TYR A 327
LEU A 330
ILE A 341
MET A 348
MET A 364
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.47A 2xkwA-3b0qA:
42.6
2xkwA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 7 LEU A 255
GLU A 259
ILE A 281
GLN A 286
ARG A 288
ALA A 292
ILE A 326
None
None
MC5  A   1 ( 4.8A)
None
None
None
MC5  A   1 ( 4.9A)
0.24A 2xkwA-3b0qA:
42.6
2xkwA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 12 ILE A 249
ARG A 288
SER A 289
ALA A 292
LEU A 330
MET A 348
MET A 364
None
None
MC5  A   1 (-2.6A)
None
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
0.54A 2xkwB-3b0qA:
37.2
2xkwB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 12 ILE A 249
GLU A 259
ARG A 288
ALA A 292
LEU A 330
ILE A 341
MET A 348
MET A 364
None
None
None
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
0.57A 2xkwB-3b0qA:
37.2
2xkwB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 12 ILE A 249
GLU A 259
CYH A 285
ARG A 288
ALA A 292
LEU A 330
ILE A 341
MET A 364
None
None
MC5  A   1 (-3.6A)
None
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
0.78A 2xkwB-3b0qA:
37.2
2xkwB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 6 LEU A 255
ARG A 280
ILE A 281
ILE A 326
MET A 329
None
None
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.9A)
None
0.65A 2xkwB-3b0qA:
37.2
2xkwB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 6 LEU A 255
ILE A 281
ILE A 326
MET A 329
LEU A 333
None
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.9A)
None
None
0.28A 2xkwB-3b0qA:
37.2
2xkwB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 10 GLU A 259
ARG A 280
ILE A 281
GLY A 284
LEU A 330
ILE A 341
MET A 348
MET A 364
None
None
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
0.72A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 10 GLU A 259
ILE A 281
GLY A 284
ARG A 288
LEU A 330
ILE A 341
MET A 348
MET A 364
None
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.5A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
0.52A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 10 GLU A 259
ILE A 281
GLY A 284
CYH A 285
ARG A 288
LEU A 330
ILE A 341
MET A 364
None
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
0.65A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
9 / 12 CYH A 285
HIS A 323
LEU A 330
LEU A 353
LYS A 367
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.62A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 CYH A 285
LEU A 356
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.32A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.13A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
SER A 289
HIS A 323
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.87A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
9 / 12 SER A 289
HIS A 323
LEU A 330
LEU A 353
LYS A 367
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.59A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 6 ILE A 281
ILE A 326
TYR A 327
LEU A 356
PHE A 360
MET A 364
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.9A)
None
None
None
MC5  A   1 (-3.7A)
0.37A 3adsA-3b0qA:
42.0
3adsA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 12 GLY A 284
ARG A 288
SER A 289
ALA A 292
ILE A 326
LEU A 330
LEU A 333
VAL A 339
MC5  A   1 ( 4.5A)
None
MC5  A   1 (-2.6A)
None
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.6A)
0.59A 3adsB-3b0qA:
36.8
3adsB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 12 GLY A 284
CYH A 285
ARG A 288
LEU A 330
LEU A 333
VAL A 339
MET A 364
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.6A)
MC5  A   1 (-3.7A)
0.77A 3adsB-3b0qA:
36.8
3adsB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
10 / 12 ILE A 281
GLY A 284
ARG A 288
ALA A 292
ILE A 326
LEU A 330
LEU A 333
VAL A 339
ILE A 341
MET A 364
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.5A)
None
None
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
0.44A 3adsB-3b0qA:
36.8
3adsB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
9 / 12 CYH A 285
GLN A 286
HIS A 323
TYR A 327
LEU A 330
LEU A 353
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
None
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.66A 3adxA-3b0qA:
41.4
3adxA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 CYH A 285
GLN A 286
LEU A 356
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
None
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.39A 3adxA-3b0qA:
41.4
3adxA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
9 / 12 GLN A 286
SER A 289
HIS A 323
TYR A 327
LEU A 330
LEU A 353
HIS A 449
LEU A 469
TYR A 473
None
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.69A 3adxA-3b0qA:
41.4
3adxA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 PHE A 282
CYH A 285
GLN A 286
HIS A 323
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-3.8A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.07A 3adxA-3b0qA:
41.4
3adxA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 PHE A 282
GLN A 286
SER A 289
HIS A 323
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
None
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.89A 3adxA-3b0qA:
41.4
3adxA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 7 ILE A 281
ILE A 326
LEU A 356
MET A 364
LYS A 367
LEU A 453
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.9A)
None
MC5  A   1 (-3.7A)
None
MC5  A   1 (-4.2A)
0.52A 3adxA-3b0qA:
41.4
3adxA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 7 ILE A 281
ILE A 326
LEU A 356
PHE A 360
MET A 364
LYS A 367
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.9A)
None
None
MC5  A   1 (-3.7A)
None
0.33A 3adxA-3b0qA:
41.4
3adxA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 LEU A 228
GLY A 284
ARG A 288
SER A 289
ALA A 292
ILE A 326
LEU A 330
LEU A 333
VAL A 339
ILE A 341
MET A 364
None
MC5  A   1 ( 4.5A)
None
MC5  A   1 (-2.6A)
None
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
0.57A 3adxB-3b0qA:
36.8
3adxB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
9 / 12 LEU A 228
GLY A 284
CYH A 285
ARG A 288
ALA A 292
LEU A 330
LEU A 333
VAL A 339
MET A 364
None
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.6A)
MC5  A   1 (-3.7A)
0.80A 3adxB-3b0qA:
36.8
3adxB-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 CYH A 285
HIS A 323
ILE A 326
LEU A 330
MET A 364
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
0.85A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 CYH A 285
HIS A 323
LEU A 330
MET A 364
LYS A 367
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
None
0.96A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 GLY A 284
CYH A 285
SER A 289
ILE A 326
LEU A 330
MET A 364
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
0.92A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 12 GLY A 284
CYH A 285
SER A 289
LEU A 330
MET A 364
LYS A 367
HIS A 449
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
None
MC5  A   1 (-3.9A)
1.15A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 GLY A 284
MET A 364
LYS A 367
HIS A 449
LEU A 453
TYR A 473
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.7A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.9A)
1.25A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 12 GLY A 284
SER A 289
ILE A 326
LEU A 330
MET A 364
LEU A 469
TYR A 473
MC5  A   1 ( 4.5A)
MC5  A   1 (-2.6A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.64A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 12 GLY A 284
SER A 289
LEU A 330
MET A 364
LYS A 367
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 ( 4.5A)
MC5  A   1 (-2.6A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.09A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 HIS A 323
ILE A 326
LEU A 330
MET A 364
TYR A 473
MC5  A   1 (-3.8A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
MC5  A   1 (-4.9A)
0.74A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 HIS A 323
LEU A 330
MET A 364
LYS A 367
TYR A 473
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
None
MC5  A   1 (-4.9A)
0.82A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 HIS A 323
MET A 364
LYS A 367
LEU A 453
TYR A 473
MC5  A   1 (-3.8A)
MC5  A   1 (-3.7A)
None
MC5  A   1 (-4.2A)
MC5  A   1 (-4.9A)
1.01A 3cs8A-3b0qA:
38.9
3cs8A-3b0qA:
98.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 12 PHE A 282
ARG A 288
SER A 289
HIS A 323
TYR A 327
HIS A 449
TYR A 473
MC5  A   1 (-4.4A)
None
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
1.17A 3dzyD-3b0qA:
22.5
3dzyD-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 PHE A 282
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
VAL A 339
LEU A 353
MET A 364
HIS A 449
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
MC5  A   1 (-4.7A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.62A 3dzyD-3b0qA:
22.5
3dzyD-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
4 / 4 ILE A 281
GLN A 286
ILE A 341
LEU A 453
MC5  A   1 ( 4.8A)
None
MC5  A   1 (-4.5A)
MC5  A   1 (-4.2A)
0.67A 3dzyD-3b0qA:
22.5
3dzyD-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 CYH A 285
SER A 289
MET A 364
HIS A 449
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.92A 3g8iA-3b0qA:
36.7
3g8iA-3b0qA:
61.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 SER A 289
MET A 334
MET A 364
HIS A 449
TYR A 473
MC5  A   1 (-2.6A)
None
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
1.27A 3g8iA-3b0qA:
36.7
3g8iA-3b0qA:
61.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 7 GLN A 286
LEU A 330
LEU A 353
LYS A 367
LEU A 469
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
None
MC5  A   1 (-4.1A)
0.72A 3g8iA-3b0qA:
36.7
3g8iA-3b0qA:
61.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 7 LEU A 255
GLN A 286
LEU A 330
LEU A 353
LYS A 367
None
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
None
0.92A 3g8iA-3b0qA:
36.7
3g8iA-3b0qA:
61.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 GLY A 284
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
VAL A 339
ILE A 341
LYS A 367
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.54A 3g9eA-3b0qA:
40.3
3g9eA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 10 PHE A 282
GLN A 286
ILE A 326
MET A 329
LEU A 353
LYS A 367
MC5  A   1 (-4.4A)
None
MC5  A   1 ( 4.9A)
None
MC5  A   1 (-4.7A)
None
0.65A 3gwxA-3b0qA:
36.2
3gwxA-3b0qA:
61.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 CYH A 285
HIS A 323
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.67A 3gwxA-3b0qA:
36.2
3gwxA-3b0qA:
61.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.87A 3gwxA-3b0qA:
36.2
3gwxA-3b0qA:
61.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 12 CYH A 285
GLU A 295
HIS A 323
LEU A 330
LYS A 367
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
None
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.78A 3gwxB-3b0qA:
36.6
3gwxB-3b0qA:
61.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 GLU A 291
HIS A 323
LEU A 330
LYS A 367
HIS A 449
TYR A 473
None
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
1.26A 3gwxB-3b0qA:
36.6
3gwxB-3b0qA:
61.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 LEU A 255
PHE A 282
GLN A 286
ILE A 326
MET A 329
LEU A 353
None
MC5  A   1 (-4.4A)
None
MC5  A   1 ( 4.9A)
None
MC5  A   1 (-4.7A)
0.69A 3gwxB-3b0qA:
36.6
3gwxB-3b0qA:
61.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
10 / 12 ARG A 288
ALA A 292
TYR A 327
LEU A 330
ILE A 341
MET A 348
PHE A 363
MET A 364
LYS A 367
HIS A 449
None
None
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
None
MC5  A   1 (-3.7A)
None
MC5  A   1 (-3.9A)
0.72A 3qt0A-3b0qA:
38.5
3qt0A-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
10 / 12 CYH A 285
ARG A 288
ALA A 292
TYR A 327
LEU A 330
ILE A 341
MET A 348
PHE A 363
LYS A 367
HIS A 449
MC5  A   1 (-3.6A)
None
None
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
None
None
MC5  A   1 (-3.9A)
0.61A 3qt0A-3b0qA:
38.5
3qt0A-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
10 / 12 CYH A 285
ARG A 288
SER A 289
ALA A 292
LEU A 330
ILE A 341
MET A 348
PHE A 363
LYS A 367
HIS A 449
MC5  A   1 (-3.6A)
None
MC5  A   1 (-2.6A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
None
None
MC5  A   1 (-3.9A)
0.77A 3qt0A-3b0qA:
38.5
3qt0A-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 CYH A 285
SER A 289
MET A 364
HIS A 449
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.75A 3sp6A-3b0qA:
38.0
3sp6A-3b0qA:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
HIS A 323
ILE A 326
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.9A)
0.86A 3sp9A-3b0qA:
36.4
3sp9A-3b0qA:
61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
ILE A 326
HIS A 449
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
1.19A 3sp9A-3b0qA:
36.4
3sp9A-3b0qA:
61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
HIS A 323
ILE A 326
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-3.8A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.9A)
0.88A 3sp9B-3b0qA:
36.2
3sp9B-3b0qA:
61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
ILE A 326
HIS A 449
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
1.14A 3sp9B-3b0qA:
36.2
3sp9B-3b0qA:
61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
9 / 12 CYH A 285
SER A 289
ILE A 326
TYR A 327
LEU A 330
LEU A 353
MET A 364
HIS A 449
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 ( 4.9A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.7A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.72A 3vn2A-3b0qA:
40.5
3vn2A-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
SER A 289
ILE A 326
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.9A)
0.85A 3vn2A-3b0qA:
40.5
3vn2A-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 SER A 289
ILE A 326
LEU A 330
PHE A 282
TYR A 473
MC5  A   1 (-2.6A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.9A)
1.20A 3vn2A-3b0qA:
40.5
3vn2A-3b0qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 368
VAL A 339
ILE A 341
GLU A 365
ILE A 445
None
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
None
None
1.27A 4a97B-3b0qA:
undetectable
4a97C-3b0qA:
undetectable
4a97B-3b0qA:
20.00
4a97C-3b0qA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 GLY A 284
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
MET A 348
MET A 364
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.52A 4emaA-3b0qA:
40.9
4emaA-3b0qA:
98.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 GLY A 284
CYH A 285
TYR A 327
LEU A 330
LEU A 452
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-4.4A)
None
1.31A 4emaA-3b0qA:
40.9
4emaA-3b0qA:
98.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
3 / 3 PHE A 282
VAL A 339
ILE A 341
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
0.38A 4emaA-3b0qA:
40.9
4emaA-3b0qA:
98.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
8 / 12 PHE A 282
ARG A 288
SER A 289
TYR A 327
MET A 364
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
None
MC5  A   1 (-2.6A)
None
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
1.31A 4o8fA-3b0qA:
38.8
4o8fA-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 PHE A 282
CYH A 285
MET A 348
MET A 364
HIS A 449
LEU A 465
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
None
1.41A 4o8fA-3b0qA:
38.8
4o8fA-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 PHE A 282
CYH A 285
SER A 289
HIS A 323
TYR A 327
VAL A 339
MET A 348
MET A 364
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.6A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.37A 4o8fA-3b0qA:
38.8
4o8fA-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 5 GLY A 284
LEU A 330
ILE A 341
LEU A 353
LEU A 453
MC5  A   1 ( 4.5A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 (-4.7A)
MC5  A   1 (-4.2A)
0.51A 4o8fA-3b0qA:
38.8
4o8fA-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
4 / 5 GLY A 284
LEU A 353
ILE A 341
LEU A 255
MC5  A   1 ( 4.5A)
MC5  A   1 (-4.7A)
MC5  A   1 (-4.5A)
None
0.84A 4o8fA-3b0qA:
38.8
4o8fA-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 CYH A 285
SER A 289
HIS A 323
LEU A 330
VAL A 339
MET A 348
MET A 364
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.61A 4o8fB-3b0qA:
21.7
4o8fB-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 12 CYH A 285
SER A 289
LEU A 330
VAL A 339
PHE A 363
MET A 364
HIS A 449
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
None
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
0.73A 4o8fB-3b0qA:
21.7
4o8fB-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 SER A 289
HIS A 323
PHE A 282
HIS A 449
TYR A 473
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
1.47A 4o8fB-3b0qA:
21.7
4o8fB-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 6 ILE A 281
GLY A 284
ILE A 326
ILE A 341
LEU A 353
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.5A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.5A)
MC5  A   1 (-4.7A)
0.59A 4o8fB-3b0qA:
37.8
4o8fB-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 6 ILE A 281
PHE A 282
GLY A 284
ILE A 341
LEU A 353
MC5  A   1 ( 4.8A)
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-4.5A)
MC5  A   1 (-4.7A)
0.68A 4o8fB-3b0qA:
37.8
4o8fB-3b0qA:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 8 CYH A 285
LEU A 330
LEU A 333
VAL A 339
ILE A 341
MET A 364
MC5  A   1 (-3.6A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
0.67A 4oj4A-3b0qA:
37.4
4oj4A-3b0qA:
98.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 8 SER A 289
LEU A 330
LEU A 333
VAL A 339
MET A 364
MC5  A   1 (-2.6A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.6A)
MC5  A   1 (-3.7A)
0.65A 4oj4A-3b0qA:
37.4
4oj4A-3b0qA:
98.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 PHE A 282
GLY A 284
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
MET A 364
HIS A 449
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.48A 4xldA-3b0qA:
39.8
4xldA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 12 PHE A 282
GLY A 284
CYH A 285
SER A 289
LEU A 330
PHE A 363
MET A 364
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-3.7A)
0.87A 4xldA-3b0qA:
39.8
4xldA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 SER A 289
HIS A 323
PHE A 282
HIS A 449
TYR A 473
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.4A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
1.12A 4xldA-3b0qA:
39.8
4xldA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 9 ALA A 292
GLU A 295
MET A 329
LEU A 330
LEU A 333
ILE A 341
None
None
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.5A)
0.43A 4xtaA-3b0qA:
37.9
4xtaA-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 9 CYH A 285
GLU A 295
MET A 329
LEU A 330
LEU A 333
ILE A 341
MC5  A   1 (-3.6A)
None
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.5A)
0.71A 4xtaA-3b0qA:
37.9
4xtaA-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 9 SER A 289
ALA A 292
GLU A 295
MET A 329
LEU A 330
LEU A 333
MC5  A   1 (-2.6A)
None
None
None
MC5  A   1 (-4.4A)
None
0.57A 4xtaA-3b0qA:
37.9
4xtaA-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 8 CYH A 285
ARG A 288
LEU A 330
LEU A 333
ILE A 341
MET A 364
MC5  A   1 (-3.6A)
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
0.83A 4xtaB-3b0qA:
36.3
4xtaB-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 8 ILE A 281
ARG A 288
LEU A 330
LEU A 333
ILE A 341
MET A 364
MC5  A   1 ( 4.8A)
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
0.51A 4xtaB-3b0qA:
36.3
4xtaB-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 8 ILE A 281
ARG A 288
SER A 289
LEU A 330
LEU A 333
MET A 364
MC5  A   1 ( 4.8A)
None
MC5  A   1 (-2.6A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-3.7A)
0.57A 4xtaB-3b0qA:
36.3
4xtaB-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
10 / 12 CYH A 285
SER A 289
HIS A 323
ILE A 326
MET A 364
HIS A 449
LEU A 453
LEU A 465
LEU A 469
TYR A 473
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
None
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.70A 4xumA-3b0qA:
41.1
4xumA-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 HIS A 323
ILE A 326
PHE A 282
LEU A 453
TYR A 473
MC5  A   1 (-3.8A)
MC5  A   1 ( 4.9A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.9A)
1.09A 4xumA-3b0qA:
41.1
4xumA-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
SER A 289
HIS A 323
LEU A 469
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.1A)
0.94A 4xumA-3b0qA:
41.1
4xumA-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 7 GLU A 259
ILE A 281
CYH A 285
ARG A 288
LEU A 330
ILE A 341
MET A 348
None
MC5  A   1 ( 4.8A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
0.54A 4xumA-3b0qA:
41.1
4xumA-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
10 / 11 GLY A 284
ARG A 288
SER A 289
ALA A 292
ILE A 326
MET A 329
LEU A 330
LEU A 333
ILE A 341
MET A 348
MC5  A   1 ( 4.5A)
None
MC5  A   1 (-2.6A)
None
MC5  A   1 ( 4.9A)
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
0.55A 4xumB-3b0qA:
36.3
4xumB-3b0qA:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
7 / 11 GLY A 284
CYH A 285
ARG A 288
ALA A 292
MET A 329
LEU A 330
LEU A 333
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
None
None
MC5  A   1 (-4.4A)
None
0.86A 4xumB-3b0qA:
36.3
4xumB-3b0qA:
98.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 9 LEU A 353
THR A 349
ILE A 341
PRO A 246
LEU A 340
MC5  A   1 (-4.7A)
None
MC5  A   1 (-4.5A)
None
None
1.31A 5g48B-3b0qA:
undetectable
5g48B-3b0qA:
24.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 PHE A 282
GLY A 284
CYH A 285
GLN A 286
SER A 289
HIS A 323
TYR A 327
LEU A 330
MET A 364
HIS A 449
LEU A 453
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.9A)
0.58A 5ji0D-3b0qA:
40.5
5ji0D-3b0qA:
98.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 PHE A 282
CYH A 285
LEU A 330
PHE A 363
MET A 364
LEU A 453
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-4.4A)
None
MC5  A   1 (-3.7A)
MC5  A   1 (-4.2A)
0.90A 5y2oA-3b0qA:
40.9
5y2oA-3b0qA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 PHE A 282
CYH A 285
MET A 364
HIS A 449
LEU A 465
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
None
1.50A 5y2oA-3b0qA:
40.9
5y2oA-3b0qA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 PHE A 282
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
MET A 364
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.57A 5y2oA-3b0qA:
40.9
5y2oA-3b0qA:
73.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 12 LEU A 255
CYH A 285
LEU A 330
ILE A 341
MET A 348
LEU A 465
None
MC5  A   1 (-3.6A)
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
None
1.23A 5y2tA-3b0qA:
40.2
5y2tA-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 LEU A 255
PHE A 282
GLY A 284
CYH A 285
GLN A 286
TYR A 327
LEU A 330
ILE A 341
MET A 348
MET A 364
HIS A 449
LEU A 453
None
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
0.60A 5y2tA-3b0qA:
40.2
5y2tA-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
3 / 3 SER A 289
HIS A 323
TYR A 473
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.9A)
0.34A 5y2tA-3b0qA:
40.2
5y2tA-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
11 / 12 LEU A 255
ARG A 280
ILE A 281
CYH A 285
GLN A 286
ILE A 326
TYR A 327
LEU A 330
ILE A 341
MET A 348
HIS A 449
None
None
MC5  A   1 ( 4.8A)
MC5  A   1 (-3.6A)
None
MC5  A   1 ( 4.9A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.9A)
0.61A 5y2tB-3b0qA:
36.8
5y2tB-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 LEU A 255
ILE A 281
GLN A 283
ILE A 341
MET A 348
None
MC5  A   1 ( 4.8A)
None
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
1.08A 5y2tB-3b0qA:
36.8
5y2tB-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 8 GLU A 259
PHE A 282
PHE A 363
MET A 364
LEU A 453
None
MC5  A   1 (-4.4A)
None
MC5  A   1 (-3.7A)
MC5  A   1 (-4.2A)
1.00A 5y2tB-3b0qA:
36.8
5y2tB-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 8 GLU A 259
PHE A 282
SER A 289
HIS A 323
MET A 364
None
MC5  A   1 (-4.4A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-3.7A)
0.79A 5y2tB-3b0qA:
36.8
5y2tB-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 8 GLU A 259
PHE A 282
SER A 289
MET A 364
LEU A 453
None
MC5  A   1 (-4.4A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.7A)
MC5  A   1 (-4.2A)
0.89A 5y2tB-3b0qA:
36.8
5y2tB-3b0qA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 LEU A 255
ARG A 280
ILE A 281
GLY A 284
TYR A 327
LEU A 330
VAL A 339
ILE A 341
MET A 348
MET A 364
LEU A 453
LEU A 469
None
None
MC5  A   1 ( 4.8A)
MC5  A   1 ( 4.5A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.6A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
MC5  A   1 (-3.7A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
0.57A 5ycnA-3b0qA:
41.8
5ycnA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
5 / 12 LEU A 255
ILE A 281
ILE A 341
MET A 348
LEU A 465
None
MC5  A   1 ( 4.8A)
MC5  A   1 (-4.5A)
MC5  A   1 ( 4.0A)
None
1.04A 5ycnA-3b0qA:
41.8
5ycnA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
6 / 6 PHE A 282
CYH A 285
SER A 289
HIS A 323
HIS A 449
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.39A 5ycnA-3b0qA:
41.8
5ycnA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 PHE A 282
CYH A 285
SER A 289
HIS A 323
TYR A 327
LEU A 330
ILE A 341
MET A 364
HIS A 449
LEU A 453
LEU A 469
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 (-3.6A)
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.2A)
MC5  A   1 (-4.1A)
MC5  A   1 (-4.9A)
0.46A 5ycpA-3b0qA:
41.9
5ycpA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
3 / 3 GLY A 284
VAL A 339
MET A 348
MC5  A   1 ( 4.5A)
MC5  A   1 (-4.6A)
MC5  A   1 ( 4.0A)
0.21A 5ycpA-3b0qA:
41.9
5ycpA-3b0qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo
sapiens)
12 / 12 PHE A 282
GLY A 284
CYH A 285
GLN A 286
SER A 289
HIS A 323
TYR A 327
LEU A 330
ILE A 341
MET A 364
HIS A 449
TYR A 473
MC5  A   1 (-4.4A)
MC5  A   1 ( 4.5A)
MC5  A   1 (-3.6A)
None
MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
None
MC5  A   1 (-4.4A)
MC5  A   1 (-4.5A)
MC5  A   1 (-3.7A)
MC5  A   1 (-3.9A)
MC5  A   1 (-4.9A)
0.58A 6md4A-3b0qA:
40.8
6md4A-3b0qA:
100.00