SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MAY'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FKP_A_NVPA999_1 (HIV-1 RT, A-CHAIN) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 11 | LEU A 496ASN A 498TYR A 493GLY A 239LEU A 372 | NoneNoneNoneMAY A 600 (-3.6A)MAY A 600 (-4.6A) | 1.40A | 1fkpA-1mt5A:undetectable | 1fkpA-1mt5A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ONI_A_BEZA502_0 (14.5 KDATRANSLATIONALINHIBITOR PROTEIN) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 4 / 6 | ASN A 498ARG A 243ILE A 491GLY A 239 | NoneNoneMAY A 600 (-4.0A)MAY A 600 (-3.6A) | 0.99A | 1oniA-1mt5A:0.01oniB-1mt5A:0.0 | 1oniA-1mt5A:13.041oniB-1mt5A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ONI_D_BEZD508_0 (14.5 KDATRANSLATIONALINHIBITOR PROTEIN) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 4 / 6 | ASN A 498ARG A 243ILE A 491GLY A 239 | NoneNoneMAY A 600 (-4.0A)MAY A 600 (-3.6A) | 0.99A | 1oniD-1mt5A:0.01oniF-1mt5A:0.0 | 1oniD-1mt5A:13.041oniF-1mt5A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZW9_A_SAMA801_0 (LEUCINE CARBOXYLMETHYLTRANSFERASE 2) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | SER A 246GLY A 281GLY A 235ASP A 237LEU A 297 | NoneNoneNoneMAY A 600 (-4.4A)None | 1.21A | 2zw9A-1mt5A:undetectable | 2zw9A-1mt5A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CJT_G_SAMG302_0 (RIBOSOMAL PROTEINL11METHYLTRANSFERASE) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | LEU A 234GLY A 235SER A 217LEU A 280LEU A 261 | NoneNoneMAY A 600 (-3.1A)NoneNone | 1.17A | 3cjtG-1mt5A:undetectable | 3cjtG-1mt5A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CJT_O_SAMO302_0 (RIBOSOMAL PROTEINL11METHYLTRANSFERASE) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 6 / 12 | LEU A 234GLY A 235SER A 217VAL A 187LEU A 280LEU A 261 | NoneNoneMAY A 600 (-3.1A)NoneNoneNone | 1.26A | 3cjtO-1mt5A:undetectable | 3cjtO-1mt5A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LP1_A_NVPA701_1 (REVERSETRANSCRIPTASE/RIBONUCLEASE H) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 10 | LEU A 496ASN A 498TYR A 493GLY A 239LEU A 372 | NoneNoneNoneMAY A 600 (-3.6A)MAY A 600 (-4.6A) | 1.22A | 3lp1A-1mt5A:0.0 | 3lp1A-1mt5A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MED_A_65BA561_0 (P51 REVERSETRANSCRIPTASEP66 REVERSETRANSCRIPTASE) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | LEU A 496ASN A 498TYR A 493GLY A 239LEU A 372 | NoneNoneNoneMAY A 600 (-3.6A)MAY A 600 (-4.6A) | 1.36A | 3medA-1mt5A:0.03medB-1mt5A:0.0 | 3medA-1mt5A:21.783medB-1mt5A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4COX_A_IMNA701_1 (CYCLOOXYGENASE-2) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | VAL A 495TYR A 335LEU A 447GLY A 378ALA A 377 | MAY A 600 (-4.8A)NoneNoneNoneMAY A 600 (-3.7A) | 1.02A | 4coxA-1mt5A:undetectable | 4coxA-1mt5A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4COX_B_IMNB701_1 (CYCLOOXYGENASE-2) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | VAL A 495TYR A 335LEU A 447GLY A 378ALA A 377 | MAY A 600 (-4.8A)NoneNoneNoneMAY A 600 (-3.7A) | 1.02A | 4coxB-1mt5A:0.0 | 4coxB-1mt5A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4COX_D_IMND701_1 (CYCLOOXYGENASE-2) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | VAL A 495TYR A 335LEU A 447GLY A 378ALA A 377 | MAY A 600 (-4.8A)NoneNoneNoneMAY A 600 (-3.7A) | 1.02A | 4coxD-1mt5A:0.0 | 4coxD-1mt5A:22.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4DO3_A_0LAA602_1 (FATTY-ACID AMIDEHYDROLASE 1) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 5 | LEU A 192LEU A 404MET A 436THR A 488TRP A 531 | MAY A 600 ( 4.2A)NoneNoneMAY A 600 ( 4.2A)None | 0.77A | 4do3A-1mt5A:68.6 | 4do3A-1mt5A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4DO3_B_0LAB602_1 (FATTY-ACID AMIDEHYDROLASE 1) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 6 / 6 | LEU A 192LEU A 404ILE A 407MET A 436THR A 488TRP A 531 | MAY A 600 ( 4.2A)NoneNoneNoneMAY A 600 ( 4.2A)None | 0.80A | 4do3B-1mt5A:68.3 | 4do3B-1mt5A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OTY_B_LURB705_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | VAL A 495TYR A 335LEU A 447GLY A 378ALA A 377 | MAY A 600 (-4.8A)NoneNoneNoneMAY A 600 (-3.7A) | 1.07A | 4otyB-1mt5A:0.0 | 4otyB-1mt5A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5BYJ_A_OQRA302_0 (SULFOTRANSFERASE) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 5 / 12 | ILE A 407GLY A 384PHE A 432THR A 488LEU A 389 | NoneNoneMAY A 600 ( 4.9A)MAY A 600 ( 4.2A)None | 1.00A | 5byjA-1mt5A:undetectable | 5byjA-1mt5A:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5F1A_B_SALB601_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) | 4 / 7 | VAL A 495LEU A 447GLY A 378ALA A 377 | MAY A 600 (-4.8A)NoneNoneMAY A 600 (-3.7A) | 0.69A | 5f1aB-1mt5A:undetectable | 5f1aB-1mt5A:22.22 |