SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MAL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 8 HIS A 101
LEU A  63
THR A  62
HIS A 177
 MAL  A 500 (-4.4A)
MAL  A 500 ( 4.5A)
MAL  A 500 (-4.1A)
MAL  A 500 (-4.0A)
 1.02A 1azmA-4bzgA:
undetectable		 1azmA-4bzgA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		3 / 3 TRP A 159
VAL A 260
TRP A 341
 None
None
MAL  A 456 (-3.9A)
 1.13A 1c4dA-1mg1A:
undetectable
1c4dB-1mg1A:
undetectable		 1c4dA-1mg1A:
2.78
1c4dB-1mg1A:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40
(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		3 / 3 TRP A 158
VAL A 259
TRP A 340
 None
None
MAL  A 466 (-2.6A)
 1.26A 1c4dA-3a3cA:
undetectable
1c4dB-3a3cA:
undetectable		 1c4dA-3a3cA:
5.21
1c4dB-3a3cA:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A-191
VAL A -90
TRP A  -9
 None
None
MAL  A 126 (-3.7A)
 1.28A 1c4dA-3ehsA:
undetectable
1c4dB-3ehsA:
undetectable		 1c4dA-3ehsA:
3.13
1c4dB-3ehsA:
3.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4b3n MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5
(Escherichia
coli;
Macaca
mulatta) 		3 / 3 TRP A 158
VAL A 259
TRP A 340
 None
None
MAL  A 500 (-3.9A)
 1.30A 1c4dA-4b3nA:
undetectable
1c4dB-4b3nA:
undetectable		 1c4dA-4b3nA:
5.21
1c4dB-4b3nA:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A 159
VAL A 260
TRP A 341
 None
None
MAL  A 501 (-3.7A)
 1.28A 1c4dA-4ifpA:
undetectable
1c4dB-4ifpA:
undetectable		 1c4dA-4ifpA:
2.78
1c4dB-4ifpA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		3 / 3 TRP A 159
VAL A 260
TRP A 341
 None
None
MAL  A 501 (-3.7A)
 1.30A 1c4dA-4kv3A:
undetectable
1c4dB-4kv3A:
undetectable		 1c4dA-4kv3A:
2.05
1c4dB-4kv3A:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A 160
VAL A 261
TRP A 342
 None
None
MAL  A1201 (-3.6A)
 1.30A 1c4dA-4my2A:
undetectable
1c4dB-4my2A:
undetectable		 1c4dA-4my2A:
5.21
1c4dB-4my2A:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Escherichia
coli;
Clostridioides
difficile) 		3 / 3 TRP A 158
VAL A 259
TRP A 340
 None
None
MAL  A 601 (-3.8A)
 1.28A 1c4dA-4pe2A:
undetectable
1c4dB-4pe2A:
undetectable		 1c4dA-4pe2A:
5.21
1c4dB-4pe2A:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		3 / 3 TRP A 160
VAL A 261
TRP A 342
 None
None
MAL  A1401 (-3.7A)
 1.29A 1c4dA-4xaiA:
undetectable
1c4dB-4xaiA:
undetectable		 1c4dA-4xaiA:
3.05
1c4dB-4xaiA:
3.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A 160
VAL A 261
TRP A 342
 None
None
MAL  A1900 ( 4.0A)
 1.27A 1c4dA-4xajA:
undetectable
1c4dB-4xajA:
undetectable		 1c4dA-4xajA:
2.12
1c4dB-4xajA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Escherichia
coli;
Acinetobacter
nosocomialis) 		3 / 3 TRP A 158
VAL A 259
TRP A 340
 None
None
MAL  A1201 (-3.7A)
 1.25A 1c4dA-5cfvA:
undetectable
1c4dB-5cfvA:
undetectable		 1c4dA-5cfvA:
5.21
1c4dB-5cfvA:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		3 / 3 TRP A 159
VAL A 260
TRP A 341
 None
None
MAL  A 501 (-3.7A)
 1.29A 1c4dA-5gpqA:
undetectable
1c4dB-5gpqA:
undetectable		 1c4dA-5gpqA:
5.21
1c4dB-5gpqA:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A 158
VAL A 259
TRP A 340
 None
None
MAL  A1501 (-3.8A)
 1.29A 1c4dA-5tj2A:
undetectable
1c4dB-5tj2A:
undetectable		 1c4dA-5tj2A:
1.89
1c4dB-5tj2A:
1.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TRP A 160
VAL A 261
TRP A 342
 None
None
MAL  A2201 (-3.7A)
 1.28A 1c4dA-5v6yA:
undetectable
1c4dB-5v6yA:
undetectable		 1c4dA-5v6yA:
undetectable
1c4dB-5v6yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		3 / 3 TRP A 159
VAL A 260
TRP A 341
 None
None
MAL  A 501 (-2.7A)
 1.22A 1c4dA-5z0rA:
undetectable
1c4dB-5z0rA:
undetectable		 1c4dA-5z0rA:
undetectable
1c4dB-5z0rA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1qho ALPHA-AMYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 612
LYS A 650
GLY A 665
ASN A 667
 MAL  A1201 (-3.8A)
MAL  A1201 (-2.7A)
None
MAL  A1201 (-3.0A)
 1.04A 1dedA-1qhoA:
56.0		 1dedA-1qhoA:
45.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1qho ALPHA-AMYLASE
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 612
LYS A 650
TRP A 662
ASN A 667
 MAL  A1201 (-3.8A)
MAL  A1201 (-2.7A)
MAL  A1201 (-3.7A)
MAL  A1201 (-3.0A)
 0.29A 1dedA-1qhoA:
56.0		 1dedA-1qhoA:
45.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Drosophila
melanogaster;
Escherichia
coli) 		3 / 3 GLU P 110
TRP P 229
LYS P 272
 MAL  P 727 (-2.8A)
MAL  P 727 ( 4.7A)
None
 1.21A 1qu2A-1r6zP:
undetectable		 1qu2A-1r6zP:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40
(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		3 / 3 GLU A 111
TRP A 230
LYS A 273
 MAL  A 466 (-3.1A)
MAL  A 466 (-3.7A)
None
 1.43A 1qu2A-3a3cA:
undetectable		 1qu2A-3a3cA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU A-233
TRP A-114
LYS A -71
 MAL  A 194 (-2.9A)
MAL  A 194 ( 4.6A)
None
 1.20A 1qu2A-3l2jA:
undetectable		 1qu2A-3l2jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU A 112
TRP A 231
LYS A 274
 MAL  A 501 (-2.9A)
MAL  A 501 ( 4.6A)
None
 1.31A 1qu2A-4ikmA:
undetectable		 1qu2A-4ikmA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU A 113
TRP A 232
LYS A 275
 MAL  A1201 (-3.1A)
MAL  A1201 ( 4.6A)
None
 1.20A 1qu2A-4my2A:
undetectable		 1qu2A-4my2A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		3 / 3 GLU A 113
TRP A 232
LYS A 275
 MAL  A1301 (-2.8A)
MAL  A1301 (-4.6A)
None
 1.34A 1qu2A-4nufA:
undetectable		 1qu2A-4nufA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU A 135
TRP A 254
LYS A 297
 MAL  A 801 (-2.8A)
MAL  A 801 ( 3.6A)
None
 1.05A 1qu2A-4wrnA:
undetectable		 1qu2A-4wrnA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		3 / 3 GLU A 113
TRP A 232
LYS A 275
 MAL  A1401 (-3.0A)
MAL  A1401 (-4.3A)
None
 1.37A 1qu2A-4xaiA:
2.2		 1qu2A-4xaiA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Acinetobacter
nosocomialis;
Escherichia
coli) 		3 / 3 GLU A 111
TRP A 230
LYS A 273
 MAL  A1201 (-3.0A)
MAL  A1201 ( 4.5A)
None
 1.24A 1qu2A-5cfvA:
undetectable		 1qu2A-5cfvA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19
(Escherichia
coli;
Tetrahymena
thermophila) 		3 / 3 GLU A 111
TRP A 230
LYS A 273
 MAL  A 601 (-3.0A)
MAL  A 601 ( 4.9A)
None
 1.28A 1qu2A-5dfmA:
undetectable		 1qu2A-5dfmA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU A 478
TRP A 597
LYS A 640
 MAL  A1001 (-3.1A)
MAL  A1001 (-4.8A)
None
 1.18A 1qu2A-5hzvA:
undetectable		 1qu2A-5hzvA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		3 / 3 GLU A3778
TRP A3897
LYS A3940
 MAL  A4201 (-3.0A)
MAL  A4201 ( 3.3A)
None
 1.24A 1qu2A-5ii5A:
undetectable		 1qu2A-5ii5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		3 / 3 GLU A4080
TRP A4199
LYS A4242
 MAL  A4501 (-2.7A)
MAL  A4501 ( 3.7A)
None
 1.34A 1qu2A-5iicA:
undetectable		 1qu2A-5iicA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2
(Escherichia
coli;
Mus
musculus) 		3 / 3 GLU A-258
TRP A-139
LYS A -96
 MAL  A 701 (-2.9A)
MAL  A 701 ( 4.5A)
None
 1.24A 1qu2A-5jonA:
undetectable		 1qu2A-5jonA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU A 111
TRP A 230
LYS A 273
 MAL  A1501 (-3.0A)
MAL  A1501 ( 4.6A)
None
 1.20A 1qu2A-5tj2A:
undetectable		 1qu2A-5tj2A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Bacillus
cytotoxicus) 		4 / 7 PHE A 174
ASN A  25
PHE A  28
SER A  17
 MAL  A 501 (-3.0A)
MAL  A 501 (-3.9A)
MAL  A 501 (-4.6A)
None
 1.33A 1rqpB-3k4hA:
3.5		 1rqpB-3k4hA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Bacillus
cytotoxicus) 		4 / 7 MET A 197
PHE A 136
ARG A 147
ASN A 115
 None
None
None
MAL  A 501 (-3.1A)
 1.17A 1t9wA-3k4hA:
undetectable		 1t9wA-3k4hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Escherichia
coli;
Drosophila
melanogaster) 		5 / 10 LEU P 191
LEU P 194
ILE P 160
GLU P 152
LEU P 150
 None
None
None
MAL  P 727 (-3.6A)
None
 1.24A 1wopA-1r6zP:
0.0		 1wopA-1r6zP:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		5 / 10 LEU A-157
LEU A-154
ILE A-188
GLU A-196
LEU A-198
 None
None
None
MAL  A 126 (-3.8A)
None
 1.22A 1wopA-3ehsA:
undetectable		 1wopA-3ehsA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		5 / 10 LEU A 192
LEU A 195
ILE A 161
GLU A 153
LEU A 151
 None
None
None
MAL  A1122 (-3.6A)
None
 1.17A 1wopA-3oaiA:
undetectable		 1wopA-3oaiA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 10 LEU A 192
LEU A 195
ILE A 161
GLU A 153
LEU A 151
 None
None
None
MAL  A 700 (-3.6A)
None
 1.24A 1wopA-3osrA:
undetectable		 1wopA-3osrA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		5 / 10 LEU A 193
LEU A 196
ILE A 162
GLU A 154
LEU A 152
 None
None
None
MAL  A 501 (-3.6A)
None
 1.24A 1wopA-4ikmA:
undetectable		 1wopA-4ikmA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 10 LEU A 194
LEU A 197
ILE A 163
GLU A 155
LEU A 153
 None
None
None
MAL  A2201 (-3.7A)
None
 1.24A 1wopA-4rwfA:
undetectable		 1wopA-4rwfA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 10 LEU A 198
LEU A 201
ILE A 167
GLU A 159
LEU A 157
 None
None
None
MAL  A 601 (-3.6A)
None
 1.20A 1wopA-4wviA:
undetectable		 1wopA-4wviA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		5 / 10 LEU A 192
LEU A 195
ILE A 161
GLU A 153
LEU A 151
 None
None
None
MAL  A 901 (-3.7A)
None
 1.16A 1wopA-5azaA:
undetectable		 1wopA-5azaA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		5 / 10 LEU A4161
LEU A4164
ILE A4130
GLU A4122
LEU A4120
 None
None
None
MAL  A4501 (-3.8A)
None
 1.21A 1wopA-5iicA:
undetectable		 1wopA-5iicA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Bacillus
cytotoxicus) 		4 / 7 PHE A 174
ASN A  25
PHE A  28
SER A  17
 MAL  A 501 (-3.0A)
MAL  A 501 (-3.9A)
MAL  A 501 (-4.6A)
None
 1.34A 2v7uB-3k4hA:
2.9		 2v7uB-3k4hA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Escherichia
coli;
Bovine
leukemia
virus) 		4 / 8 THR A 119
LEU A 311
ASP A 313
GLU A 137
 None
None
None
MAL  A1488 (-2.9A)
 1.06A 2zw9A-2xz3A:
undetectable		 2zw9A-2xz3A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A-251
LEU A -59
ASP A -57
GLU A-233
 None
None
None
MAL  A 194 (-2.9A)
 1.01A 2zw9A-3l2jA:
undetectable		 2zw9A-3l2jA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		4 / 8 THR A 831
LEU A1023
ASP A1025
GLU A 849
 None
None
None
MAL  A 600 (-2.9A)
 1.00A 2zw9A-3mp6A:
undetectable		 2zw9A-3mp6A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A-255
LEU A -63
ASP A -61
GLU A-237
 None
None
None
MAL  A5044 (-2.9A)
 1.05A 2zw9A-3n94A:
undetectable		 2zw9A-3n94A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A  93
LEU A 285
ASP A 287
GLU A 111
 None
None
None
MAL  A1122 (-2.9A)
 1.04A 2zw9A-3oaiA:
undetectable		 2zw9A-3oaiA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 8 THR A  93
LEU A 533
ASP A 535
GLU A 111
 None
None
None
MAL  A 700 (-2.9A)
 1.00A 2zw9A-3osqA:
undetectable		 2zw9A-3osqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A  93
LEU A 285
ASP A 287
GLU A 111
 None
None
None
MAL  A 601 (-2.9A)
 1.02A 2zw9A-4egcA:
undetectable		 2zw9A-4egcA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A  94
LEU A 286
ASP A 288
GLU A 112
 None
None
None
MAL  A 501 (-3.0A)
 1.01A 2zw9A-4ifpA:
undetectable		 2zw9A-4ifpA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		4 / 8 THR A  94
LEU A 286
ASP A 288
GLU A 112
 None
None
None
MAL  A 501 (-3.0A)
 1.04A 2zw9A-4kv3A:
undetectable		 2zw9A-4kv3A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A  95
LEU A 287
ASP A 289
GLU A 113
 None
None
None
MAL  A2201 (-3.0A)
 1.00A 2zw9A-4rwfA:
undetectable		 2zw9A-4rwfA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 8 THR A  99
LEU A 291
ASP A 293
GLU A 117
 None
None
None
MAL  A 601 (-2.9A)
 1.08A 2zw9A-4wviA:
undetectable		 2zw9A-4wviA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A  93
LEU A 285
ASP A 287
GLU A 111
 None
None
None
MAL  A1501 (-3.0A)
 1.01A 2zw9A-5tj2A:
undetectable		 2zw9A-5tj2A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A  95
LEU A 287
ASP A 289
GLU A 113
 None
None
None
MAL  A2201 (-3.2A)
 1.00A 2zw9A-5v6yA:
undetectable		 2zw9A-5v6yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		4 / 8 THR A  94
LEU A 286
ASP A 288
GLU A 112
 None
None
None
MAL  A 501 (-2.9A)
 1.08A 2zw9A-5wq6A:
undetectable		 2zw9A-5wq6A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 6dm8 -
(-) 		4 / 8 THR A-122
LEU A  70
ASP A  72
GLU A-104
 None
None
None
MAL  A 402 (-3.0A)
 1.04A 2zw9A-6dm8A:
undetectable		 2zw9A-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19
(Escherichia
coli;
Tetrahymena
thermophila) 		3 / 3 MET A 330
GLU A 111
ASP A  14
 MAL  A 601 ( 4.3A)
MAL  A 601 (-3.0A)
SO4  A 602 ( 4.7A)
 0.97A 3a25A-5dfmA:
undetectable		 3a25A-5dfmA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 MET A 385
GLU A 166
ASP A  69
 MAL  A 803 ( 3.5A)
MAL  A 803 (-2.7A)
None
 0.98A 3a25A-5hzwA:
undetectable		 3a25A-5hzwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 6 ASP A  15
LEU A  44
LEU A  21
TRP A  63
 MAL  A 456 (-3.4A)
None
None
MAL  A 456 (-4.3A)
 1.25A 3bj8C-1mg1A:
0.0
3bj8D-1mg1A:
0.0		 3bj8C-1mg1A:
15.71
3bj8D-1mg1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 6 ASP A  16
LEU A  45
LEU A  22
TRP A  64
 MAL  A1201 (-3.0A)
None
None
MAL  A1201 (-4.3A)
 1.27A 3bj8C-4my2A:
undetectable
3bj8D-4my2A:
undetectable		 3bj8C-4my2A:
16.81
3bj8D-4my2A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5tu0 LMO2125 PROTEIN
(Listeria
monocytogenes) 		3 / 3 TYR A 148
GLU A 143
ASP A  99
 None
MAL  A 501 ( 4.2A)
MAL  A 501 (-3.8A)
 0.86A 3bxoA-5tu0A:
undetectable		 3bxoA-5tu0A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5tu0 LMO2125 PROTEIN
(Listeria
monocytogenes) 		3 / 3 TYR A 148
GLU A 143
ASP A  99
 None
MAL  A 501 ( 4.2A)
MAL  A 501 (-3.8A)
 0.89A 3bxoB-5tu0A:
undetectable		 3bxoB-5tu0A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Bacillus
cytotoxicus) 		6 / 10 LEU A  13
GLY A 251
ALA A 254
VAL A  96
GLY A  99
ILE A  74
 None
None
None
None
MAL  A 501 (-3.3A)
None
 1.48A 3ekpD-3k4hA:
undetectable		 3ekpD-3k4hA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 6 HIS A  99
ASN A  92
ASN A  98
GLU A  93
 None
None
None
MAL  A 500 (-3.7A)
 1.44A 3galA-4bzgA:
undetectable		 3galA-4bzgA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 4hw8 BACTERIAL
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, PUTATIVE
(Staphylococcus
aureus) 		4 / 5 GLN A 362
THR A 154
GLU A 152
HIS A 105
 None
None
MAL  A 506 (-3.4A)
None
 1.34A 3glqB-4hw8A:
undetectable		 3glqB-4hw8A:
23.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		9 / 12 ASP A  15
LYS A  16
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
 MAL  A 456 (-3.4A)
MAL  A 456 (-2.8A)
None
None
MAL  A 456 (-3.1A)
MAL  A 456 (-2.8A)
MAL  A 456 (-2.6A)
MAL  A 456 (-3.5A)
MAL  A 456 ( 4.8A)
 0.60A 3jyrA-1mg1A:
59.7		 3jyrA-1mg1A:
79.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Drosophila
melanogaster;
Escherichia
coli) 		10 / 12 ASP P  13
LYS P  14
LYS P  41
GLU P  43
GLU P  44
ALA P  62
ASP P  64
ARG P  65
GLU P 110
TRP P 229
 MAL  P 727 (-3.0A)
MAL  P 727 (-2.5A)
None
None
None
MAL  P 727 (-3.1A)
MAL  P 727 (-2.6A)
MAL  P 727 (-4.0A)
MAL  P 727 (-2.8A)
MAL  P 727 ( 4.7A)
 0.68A 3jyrA-1r6zP:
61.8		 3jyrA-1r6zP:
72.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Drosophila
melanogaster;
Escherichia
coli) 		10 / 12 ASP P  13
LYS P  14
LYS P  41
GLU P  43
GLU P  44
ALA P  62
ASP P  64
GLU P 110
PRO P 153
TRP P 229
 MAL  P 727 (-3.0A)
MAL  P 727 (-2.5A)
None
None
None
MAL  P 727 (-3.1A)
MAL  P 727 (-2.6A)
MAL  P 727 (-2.8A)
MAL  P 727 (-3.4A)
MAL  P 727 ( 4.7A)
 0.37A 3jyrA-1r6zP:
61.8		 3jyrA-1r6zP:
72.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Bovine
leukemia
virus;
Escherichia
coli) 		9 / 12 ASP A  40
LYS A  41
GLU A  70
GLU A  71
ALA A  89
ASP A  91
ARG A  92
GLU A 137
TRP A 256
 MAL  A1488 (-3.0A)
MAL  A1488 (-2.5A)
None
None
MAL  A1488 (-3.2A)
MAL  A1488 (-2.8A)
MAL  A1488 (-3.8A)
MAL  A1488 (-2.9A)
MAL  A1488 (-4.5A)
 0.81A 3jyrA-2xz3A:
62.4		 3jyrA-2xz3A:
83.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Bovine
leukemia
virus;
Escherichia
coli) 		9 / 12 ASP A  40
LYS A  41
GLU A  70
GLU A  71
ALA A  89
ASP A  91
GLU A 137
PRO A 180
TRP A 256
 MAL  A1488 (-3.0A)
MAL  A1488 (-2.5A)
None
None
MAL  A1488 (-3.2A)
MAL  A1488 (-2.8A)
MAL  A1488 (-2.9A)
MAL  A1488 (-3.4A)
MAL  A1488 (-4.5A)
 0.56A 3jyrA-2xz3A:
62.4		 3jyrA-2xz3A:
83.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40
(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		9 / 12 ASP A  14
LYS A  15
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A 466 (-4.3A)
MAL  A 466 (-3.2A)
None
None
MAL  A 466 (-3.1A)
MAL  A 466 (-2.7A)
MAL  A 466 (-3.1A)
MAL  A 466 (-3.6A)
MAL  A 466 (-3.7A)
 0.46A 3jyrA-3a3cA:
60.2		 3jyrA-3a3cA:
77.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A-335
LYS A-334
GLU A-305
GLU A-304
ALA A-286
ASP A-284
ARG A-283
GLU A-238
TRP A-119
 MAL  A 126 (-2.9A)
MAL  A 126 (-2.7A)
None
None
MAL  A 126 (-3.1A)
MAL  A 126 (-2.8A)
MAL  A 126 (-4.0A)
MAL  A 126 (-2.6A)
MAL  A 126 ( 4.6A)
 0.67A 3jyrA-3ehsA:
61.2		 3jyrA-3ehsA:
72.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A-335
LYS A-334
GLU A-305
GLU A-304
ALA A-286
ASP A-284
GLU A-238
PRO A-195
TRP A-119
 MAL  A 126 (-2.9A)
MAL  A 126 (-2.7A)
None
None
MAL  A 126 (-3.1A)
MAL  A 126 (-2.8A)
MAL  A 126 (-2.6A)
MAL  A 126 (-3.6A)
MAL  A 126 ( 4.6A)
 0.53A 3jyrA-3ehsA:
61.2		 3jyrA-3ehsA:
72.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A-335
LYS A-334
LYS A-307
GLU A-305
ALA A-286
ASP A-284
ARG A-283
GLU A-238
TRP A-119
 MAL  A 126 (-2.9A)
MAL  A 126 (-2.7A)
None
None
MAL  A 126 (-3.1A)
MAL  A 126 (-2.8A)
MAL  A 126 (-4.0A)
MAL  A 126 (-2.6A)
MAL  A 126 ( 4.6A)
 0.71A 3jyrA-3ehsA:
61.2		 3jyrA-3ehsA:
72.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A-335
LYS A-334
LYS A-307
GLU A-305
ALA A-286
ASP A-284
GLU A-238
PRO A-195
TRP A-119
 MAL  A 126 (-2.9A)
MAL  A 126 (-2.7A)
None
None
MAL  A 126 (-3.1A)
MAL  A 126 (-2.8A)
MAL  A 126 (-2.6A)
MAL  A 126 (-3.6A)
MAL  A 126 ( 4.6A)
 0.52A 3jyrA-3ehsA:
61.2		 3jyrA-3ehsA:
72.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A-330
LYS A-329
LYS A-302
GLU A-300
ALA A-281
ASP A-279
ARG A-278
GLU A-233
TYR A  -3
 MAL  A 194 (-2.9A)
MAL  A 194 (-2.8A)
None
None
MAL  A 194 (-3.5A)
MAL  A 194 (-2.6A)
MAL  A 194 (-3.4A)
MAL  A 194 (-2.9A)
None
 0.91A 3jyrA-3l2jA:
53.8		 3jyrA-3l2jA:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A-330
LYS A-329
LYS A-302
GLU A-300
ALA A-281
ASP A-279
GLU A-233
PRO A-190
TRP A-114
TYR A  -3
 MAL  A 194 (-2.9A)
MAL  A 194 (-2.8A)
None
None
MAL  A 194 (-3.5A)
MAL  A 194 (-2.6A)
MAL  A 194 (-2.9A)
MAL  A 194 (-3.4A)
MAL  A 194 ( 4.6A)
None
 0.67A 3jyrA-3l2jA:
53.8		 3jyrA-3l2jA:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		10 / 12 ASP A 752
LYS A 753
LYS A 780
GLU A 782
GLU A 783
ALA A 801
ASP A 803
ARG A 804
GLU A 849
TYR A1079
 MAL  A 600 (-2.9A)
MAL  A 600 (-2.8A)
None
None
None
MAL  A 600 (-3.4A)
MAL  A 600 (-2.8A)
MAL  A 600 (-3.9A)
MAL  A 600 (-2.9A)
None
 0.91A 3jyrA-3mp6A:
62.3		 3jyrA-3mp6A:
63.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		11 / 12 ASP A 752
LYS A 753
LYS A 780
GLU A 782
GLU A 783
ALA A 801
ASP A 803
GLU A 849
PRO A 892
TRP A 968
TYR A1079
 MAL  A 600 (-2.9A)
MAL  A 600 (-2.8A)
None
None
None
MAL  A 600 (-3.4A)
MAL  A 600 (-2.8A)
MAL  A 600 (-2.9A)
MAL  A 600 (-3.4A)
MAL  A 600 (-4.3A)
None
 0.60A 3jyrA-3mp6A:
62.3		 3jyrA-3mp6A:
63.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		9 / 12 ASP A-356
LYS A-355
LYS A-328
GLU A-326
GLU A-325
ALA A-307
ASP A-305
ARG A-304
GLU A-259
 MAL  A 111 (-3.1A)
MAL  A 111 (-2.7A)
None
None
None
MAL  A 111 (-3.3A)
MAL  A 111 (-2.8A)
MAL  A 111 (-3.6A)
MAL  A 111 (-3.4A)
 0.73A 3jyrA-3n93A:
61.9		 3jyrA-3n93A:
68.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		10 / 12 ASP A-356
LYS A-355
LYS A-328
GLU A-326
GLU A-325
ALA A-307
ASP A-305
GLU A-259
PRO A-216
TRP A-140
 MAL  A 111 (-3.1A)
MAL  A 111 (-2.7A)
None
None
None
MAL  A 111 (-3.3A)
MAL  A 111 (-2.8A)
MAL  A 111 (-3.4A)
MAL  A 111 (-3.5A)
MAL  A 111 ( 4.6A)
 0.44A 3jyrA-3n93A:
61.9		 3jyrA-3n93A:
68.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A-334
LYS A-333
LYS A-306
GLU A-304
GLU A-303
ALA A-285
ASP A-283
ARG A-282
GLU A-237
TRP A-118
 MAL  A5044 (-3.1A)
MAL  A5044 (-2.7A)
None
None
None
MAL  A5044 (-3.3A)
MAL  A5044 (-2.8A)
MAL  A5044 (-3.8A)
MAL  A5044 (-2.9A)
MAL  A5044 ( 4.5A)
 0.77A 3jyrA-3n94A:
57.3		 3jyrA-3n94A:
79.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A-334
LYS A-333
LYS A-306
GLU A-304
GLU A-303
ALA A-285
ASP A-283
GLU A-237
PRO A-194
TRP A-118
 MAL  A5044 (-3.1A)
MAL  A5044 (-2.7A)
None
None
None
MAL  A5044 (-3.3A)
MAL  A5044 (-2.8A)
MAL  A5044 (-2.9A)
MAL  A5044 (-3.3A)
MAL  A5044 ( 4.5A)
 0.50A 3jyrA-3n94A:
57.3		 3jyrA-3n94A:
79.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A  14
LYS A  15
GLU A  44
GLU A  45
ALA A  63
ASP A  65
ARG A  66
GLU A 111
TRP A 230
 MAL  A1122 (-3.3A)
MAL  A1122 (-2.7A)
MAL  A1122 ( 4.8A)
None
MAL  A1122 (-3.3A)
MAL  A1122 (-2.9A)
MAL  A1122 (-3.8A)
MAL  A1122 (-2.9A)
MAL  A1122 ( 4.7A)
 0.86A 3jyrA-3oaiA:
62.1		 3jyrA-3oaiA:
69.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A  14
LYS A  15
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A1122 (-3.3A)
MAL  A1122 (-2.7A)
MAL  A1122 ( 4.8A)
None
MAL  A1122 (-3.3A)
MAL  A1122 (-2.9A)
MAL  A1122 (-2.9A)
MAL  A1122 (-3.5A)
MAL  A1122 ( 4.7A)
 0.66A 3jyrA-3oaiA:
62.1		 3jyrA-3oaiA:
69.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
ARG A  66
GLU A 111
TYR A 589
 MAL  A 700 (-2.8A)
MAL  A 700 (-2.8A)
None
None
None
MAL  A 700 (-3.3A)
MAL  A 700 (-2.8A)
MAL  A 700 (-3.6A)
MAL  A 700 (-2.9A)
None
 0.72A 3jyrA-3osqA:
45.3		 3jyrA-3osqA:
53.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		11 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 478
TYR A 589
 MAL  A 700 (-2.8A)
MAL  A 700 (-2.8A)
None
None
None
MAL  A 700 (-3.3A)
MAL  A 700 (-2.8A)
MAL  A 700 (-2.9A)
MAL  A 700 (-3.5A)
MAL  A 700 ( 4.6A)
None
 0.27A 3jyrA-3osqA:
45.3		 3jyrA-3osqA:
53.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A 700 (-3.1A)
MAL  A 700 (-2.8A)
None
None
None
MAL  A 700 (-3.3A)
MAL  A 700 (-2.8A)
MAL  A 700 (-3.0A)
MAL  A 700 (-3.6A)
MAL  A 700 ( 4.4A)
 0.37A 3jyrA-3osrA:
63.0		 3jyrA-3osrA:
53.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A  14
LYS A  15
GLU A  44
GLU A  45
ALA A  63
ASP A  65
ARG A  66
GLU A 111
TRP A 230
 MAL  A 601 (-2.9A)
MAL  A 601 (-2.7A)
None
None
MAL  A 601 (-3.2A)
MAL  A 601 (-2.9A)
MAL  A 601 (-3.8A)
MAL  A 601 (-2.9A)
MAL  A 601 (-4.5A)
 0.78A 3jyrA-4egcA:
55.6		 3jyrA-4egcA:
63.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A  14
LYS A  15
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A 601 (-2.9A)
MAL  A 601 (-2.7A)
None
None
MAL  A 601 (-3.2A)
MAL  A 601 (-2.9A)
MAL  A 601 (-2.9A)
MAL  A 601 (-3.5A)
MAL  A 601 (-4.5A)
 0.55A 3jyrA-4egcA:
55.6		 3jyrA-4egcA:
63.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
ARG A  67
GLU A 112
 MAL  A 501 (-3.0A)
MAL  A 501 (-2.6A)
None
None
None
MAL  A 501 (-3.3A)
MAL  A 501 (-2.9A)
MAL  A 501 (-3.8A)
MAL  A 501 (-3.0A)
 0.73A 3jyrA-4ifpA:
61.5		 3jyrA-4ifpA:
81.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
 MAL  A 501 (-3.0A)
MAL  A 501 (-2.6A)
None
None
None
MAL  A 501 (-3.3A)
MAL  A 501 (-2.9A)
MAL  A 501 (-3.0A)
MAL  A 501 (-3.4A)
MAL  A 501 (-4.4A)
 0.41A 3jyrA-4ifpA:
61.5		 3jyrA-4ifpA:
81.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
ARG A  67
GLU A 112
TRP A 231
 MAL  A 501 (-3.1A)
MAL  A 501 (-3.1A)
None
None
None
MAL  A 501 (-3.2A)
MAL  A 501 (-2.9A)
MAL  A 501 (-3.9A)
MAL  A 501 (-2.9A)
MAL  A 501 ( 4.6A)
 0.79A 3jyrA-4ikmA:
61.7		 3jyrA-4ikmA:
77.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
 MAL  A 501 (-3.1A)
MAL  A 501 (-3.1A)
None
None
None
MAL  A 501 (-3.2A)
MAL  A 501 (-2.9A)
MAL  A 501 (-2.9A)
MAL  A 501 (-3.3A)
MAL  A 501 ( 4.6A)
 0.53A 3jyrA-4ikmA:
61.7		 3jyrA-4ikmA:
77.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		11 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
ARG A  67
GLU A 112
TRP A 231
TYR A 342
 MAL  A 501 (-2.9A)
MAL  A 501 (-2.6A)
None
None
None
MAL  A 501 (-3.2A)
MAL  A 501 (-2.7A)
MAL  A 501 (-4.0A)
MAL  A 501 (-3.0A)
MAL  A 501 ( 4.7A)
None
 0.66A 3jyrA-4kv3A:
61.6		 3jyrA-4kv3A:
74.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		11 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
TYR A 342
 MAL  A 501 (-2.9A)
MAL  A 501 (-2.6A)
None
None
None
MAL  A 501 (-3.2A)
MAL  A 501 (-2.7A)
MAL  A 501 (-3.0A)
MAL  A 501 (-3.6A)
MAL  A 501 ( 4.7A)
None
 0.47A 3jyrA-4kv3A:
61.6		 3jyrA-4kv3A:
74.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ARG A  68
GLU A 113
TRP A 232
 MAL  A1201 (-3.0A)
MAL  A1201 (-2.5A)
None
None
None
MAL  A1201 (-3.2A)
MAL  A1201 (-3.9A)
MAL  A1201 (-3.1A)
MAL  A1201 ( 4.6A)
 0.77A 3jyrA-4my2A:
62.0		 3jyrA-4my2A:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
GLU A 113
PRO A 156
TRP A 232
 MAL  A1201 (-3.0A)
MAL  A1201 (-2.5A)
None
None
None
MAL  A1201 (-3.2A)
MAL  A1201 (-2.8A)
MAL  A1201 (-3.1A)
MAL  A1201 (-3.7A)
MAL  A1201 ( 4.6A)
 0.51A 3jyrA-4my2A:
62.0		 3jyrA-4my2A:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		9 / 12 ASP A  16
LYS A  17
GLU A  46
GLU A  47
ALA A  65
ASP A  67
ARG A  68
GLU A 113
TRP A 232
 MAL  A1301 (-3.1A)
MAL  A1301 (-3.1A)
MAL  A1301 ( 3.9A)
None
MAL  A1301 (-3.3A)
MAL  A1301 (-2.9A)
MAL  A1301 (-3.8A)
MAL  A1301 (-2.8A)
MAL  A1301 (-4.6A)
 0.96A 3jyrA-4nufA:
55.4		 3jyrA-4nufA:
58.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Clostridioides
difficile;
Escherichia
coli) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
ARG A  66
GLU A 111
TRP A 230
 MAL  A 601 (-3.1A)
MAL  A 601 (-2.8A)
None
None
None
MAL  A 601 (-3.3A)
MAL  A 601 (-2.9A)
MAL  A 601 (-3.8A)
MAL  A 601 (-3.1A)
MAL  A 601 (-4.5A)
 0.72A 3jyrA-4pe2A:
54.3		 3jyrA-4pe2A:
72.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Clostridioides
difficile;
Escherichia
coli) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A 601 (-3.1A)
MAL  A 601 (-2.8A)
None
None
None
MAL  A 601 (-3.3A)
MAL  A 601 (-2.9A)
MAL  A 601 (-3.1A)
MAL  A 601 (-3.5A)
MAL  A 601 (-4.5A)
 0.44A 3jyrA-4pe2A:
54.3		 3jyrA-4pe2A:
72.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
ARG A  68
GLU A 113
TRP A 232
 MAL  A2201 (-3.0A)
MAL  A2201 ( 2.7A)
None
None
None
MAL  A2201 (-3.4A)
MAL  A2201 (-2.8A)
MAL  A2201 (-3.8A)
MAL  A2201 (-3.0A)
MAL  A2201 ( 4.5A)
 0.64A 3jyrA-4rwfA:
61.9		 3jyrA-4rwfA:
61.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
GLU A 113
PRO A 156
TRP A 232
 MAL  A2201 (-3.0A)
MAL  A2201 ( 2.7A)
None
None
None
MAL  A2201 (-3.4A)
MAL  A2201 (-2.8A)
MAL  A2201 (-3.0A)
MAL  A2201 (-3.4A)
MAL  A2201 ( 4.5A)
 0.31A 3jyrA-4rwfA:
61.9		 3jyrA-4rwfA:
61.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN
(Escherichia
coli;
Homo
sapiens) 		11 / 12 ASP A  38
LYS A  39
GLU A  68
GLU A  69
ALA A  87
ASP A  89
ARG A  90
GLU A 135
PRO A 178
TRP A 254
TYR A 365
 MAL  A 801 (-3.0A)
MAL  A 801 (-3.0A)
None
None
MAL  A 801 (-2.8A)
MAL  A 801 (-2.8A)
None
MAL  A 801 (-2.8A)
MAL  A 801 (-3.2A)
MAL  A 801 ( 3.6A)
None
 0.73A 3jyrA-4wrnA:
59.5		 3jyrA-4wrnA:
48.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN
(Escherichia
coli;
Homo
sapiens) 		11 / 12 ASP A  38
LYS A  39
LYS A  66
GLU A  68
GLU A  69
ALA A  87
ASP A  89
ARG A  90
GLU A 135
PRO A 178
TRP A 254
 MAL  A 801 (-3.0A)
MAL  A 801 (-3.0A)
None
None
None
MAL  A 801 (-2.8A)
MAL  A 801 (-2.8A)
None
MAL  A 801 (-2.8A)
MAL  A 801 (-3.2A)
MAL  A 801 ( 3.6A)
 0.56A 3jyrA-4wrnA:
59.5		 3jyrA-4wrnA:
48.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB
(Escherichia
coli;
Staphylococcus
aureus) 		9 / 12 ASP A  20
LYS A  21
GLU A  50
GLU A  51
ALA A  69
ASP A  71
GLU A 117
PRO A 160
TRP A 236
 MAL  A 601 (-3.0A)
MAL  A 601 (-2.6A)
None
None
MAL  A 601 (-3.3A)
MAL  A 601 (-2.8A)
MAL  A 601 (-2.9A)
MAL  A 601 (-3.5A)
MAL  A 601 ( 4.6A)
 0.29A 3jyrA-4wviA:
61.6		 3jyrA-4wviA:
61.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		9 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
ARG A  68
TRP A 232
 MAL  A1401 (-3.2A)
MAL  A1401 (-2.6A)
None
None
None
MAL  A1401 (-3.4A)
MAL  A1401 (-2.7A)
MAL  A1401 (-4.3A)
MAL  A1401 (-4.3A)
 0.75A 3jyrA-4xaiA:
62.1		 3jyrA-4xaiA:
77.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		10 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
GLU A 113
PRO A 156
TRP A 232
 MAL  A1401 (-3.2A)
MAL  A1401 (-2.6A)
None
None
None
MAL  A1401 (-3.4A)
MAL  A1401 (-2.7A)
MAL  A1401 (-3.0A)
MAL  A1401 (-3.8A)
MAL  A1401 (-4.3A)
 0.50A 3jyrA-4xaiA:
62.1		 3jyrA-4xaiA:
77.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
ARG A  68
GLU A 113
TRP A 232
 MAL  A1900 (-3.2A)
MAL  A1900 (-2.2A)
None
MAL  A1900 (-3.4A)
None
MAL  A1900 (-3.3A)
MAL  A1900 (-2.8A)
MAL  A1900 (-4.1A)
MAL  A1900 (-2.8A)
MAL  A1900 ( 4.9A)
 0.94A 3jyrA-4xajA:
61.9		 3jyrA-4xajA:
58.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  47
ALA A  65
ASP A  67
GLU A 113
PRO A 156
TRP A 232
 MAL  A1900 (-3.2A)
MAL  A1900 (-2.2A)
None
None
MAL  A1900 (-3.3A)
MAL  A1900 (-2.8A)
MAL  A1900 (-2.8A)
MAL  A1900 (-3.4A)
MAL  A1900 ( 4.9A)
 0.47A 3jyrA-4xajA:
61.9		 3jyrA-4xajA:
58.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
ARG A  66
GLU A 111
TRP A 230
 MAL  A 901 (-2.9A)
MAL  A 901 (-2.8A)
None
None
None
MAL  A 901 (-3.3A)
MAL  A 901 (-2.9A)
MAL  A 901 (-3.9A)
MAL  A 901 (-3.1A)
MAL  A 901 ( 4.6A)
 0.72A 3jyrA-5azaA:
58.0		 3jyrA-5azaA:
42.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A 901 (-2.9A)
MAL  A 901 (-2.8A)
None
None
None
MAL  A 901 (-3.3A)
MAL  A 901 (-2.9A)
MAL  A 901 (-3.1A)
MAL  A 901 (-3.5A)
MAL  A 901 ( 4.6A)
 0.46A 3jyrA-5azaA:
58.0		 3jyrA-5azaA:
42.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Acinetobacter
nosocomialis;
Escherichia
coli) 		9 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
ARG A  66
GLU A 111
 MAL  A1201 (-3.0A)
MAL  A1201 (-2.8A)
None
None
None
MAL  A1201 (-3.3A)
MAL  A1201 (-2.8A)
MAL  A1201 (-3.8A)
MAL  A1201 (-3.0A)
 0.79A 3jyrA-5cfvA:
55.2		 3jyrA-5cfvA:
72.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Acinetobacter
nosocomialis;
Escherichia
coli) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A1201 (-3.0A)
MAL  A1201 (-2.8A)
None
None
None
MAL  A1201 (-3.3A)
MAL  A1201 (-2.8A)
MAL  A1201 (-3.0A)
MAL  A1201 (-3.4A)
MAL  A1201 ( 4.5A)
 0.50A 3jyrA-5cfvA:
55.2		 3jyrA-5cfvA:
72.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5edu MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HISTONE DEACETYLASE
6 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP B 122
LYS B 123
LYS B 150
GLU B 152
GLU B 153
ALA B 171
ASP B 173
GLU B 219
PRO B 262
TRP B 338
 MAL  B2505 (-3.2A)
MAL  B2505 (-2.9A)
None
None
None
MAL  B2505 (-3.3A)
MAL  B2505 (-2.7A)
MAL  B2505 (-3.2A)
MAL  B2505 (-3.7A)
MAL  B2505 ( 4.6A)
 0.57A 3jyrA-5eduB:
60.0		 3jyrA-5eduB:
47.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		9 / 12 ASP A  15
LYS A  16
GLU A  45
GLU A  46
ALA A  64
ASP A  66
ARG A  67
GLU A 112
TRP A 231
 MAL  A 501 (-3.4A)
MAL  A 501 (-3.1A)
None
None
MAL  A 501 ( 3.8A)
MAL  A 501 (-3.0A)
MAL  A 501 (-4.2A)
MAL  A 501 (-3.3A)
None
 0.80A 3jyrA-5gppA:
44.2		 3jyrA-5gppA:
78.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		9 / 12 ASP A  15
LYS A  16
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
 MAL  A 501 (-3.4A)
MAL  A 501 (-3.1A)
None
None
MAL  A 501 ( 3.8A)
MAL  A 501 (-3.0A)
MAL  A 501 (-3.3A)
MAL  A 501 (-3.8A)
None
 0.64A 3jyrA-5gppA:
44.2		 3jyrA-5gppA:
78.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		10 / 12 ASP A  15
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
ARG A  67
GLU A 112
TRP A 231
TYR A 342
 MAL  A 501 (-3.4A)
None
None
None
MAL  A 501 ( 3.8A)
MAL  A 501 (-3.0A)
MAL  A 501 (-4.2A)
MAL  A 501 (-3.3A)
None
None
 0.79A 3jyrA-5gppA:
44.2		 3jyrA-5gppA:
78.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		10 / 12 ASP A  15
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
TYR A 342
 MAL  A 501 (-3.4A)
None
None
None
MAL  A 501 ( 3.8A)
MAL  A 501 (-3.0A)
MAL  A 501 (-3.3A)
MAL  A 501 (-3.8A)
None
None
 0.60A 3jyrA-5gppA:
44.2		 3jyrA-5gppA:
78.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		9 / 12 ASP A 381
LYS A 382
LYS A 409
GLU A 411
GLU A 412
ALA A 430
ASP A 432
ARG A 433
GLU A 478
 MAL  A1001 (-3.9A)
MAL  A1001 (-3.3A)
None
None
None
MAL  A1001 (-3.2A)
MAL  A1001 (-2.8A)
MAL  A1001 (-4.0A)
MAL  A1001 (-3.1A)
 0.95A 3jyrA-5hzvA:
61.5		 3jyrA-5hzvA:
81.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A 381
LYS A 382
LYS A 409
GLU A 411
GLU A 412
ALA A 430
ASP A 432
GLU A 478
PRO A 521
TRP A 597
 MAL  A1001 (-3.9A)
MAL  A1001 (-3.3A)
None
None
None
MAL  A1001 (-3.2A)
MAL  A1001 (-2.8A)
MAL  A1001 (-3.1A)
MAL  A1001 (-3.9A)
MAL  A1001 (-4.8A)
 0.76A 3jyrA-5hzvA:
61.5		 3jyrA-5hzvA:
81.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		10 / 12 ASP A3681
LYS A3682
LYS A3709
GLU A3711
GLU A3712
ALA A3730
ASP A3732
ARG A3733
GLU A3778
TRP A3897
 MAL  A4201 (-2.6A)
MAL  A4201 (-2.3A)
None
None
None
MAL  A4201 (-3.2A)
MAL  A4201 (-2.5A)
MAL  A4201 (-3.8A)
MAL  A4201 (-3.0A)
MAL  A4201 ( 3.3A)
 0.65A 3jyrA-5ii5A:
37.7		 3jyrA-5ii5A:
68.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		10 / 12 ASP A3681
LYS A3682
LYS A3709
GLU A3711
GLU A3712
ALA A3730
ASP A3732
GLU A3778
PRO A3821
TRP A3897
 MAL  A4201 (-2.6A)
MAL  A4201 (-2.3A)
None
None
None
MAL  A4201 (-3.2A)
MAL  A4201 (-2.5A)
MAL  A4201 (-3.0A)
MAL  A4201 (-3.0A)
MAL  A4201 ( 3.3A)
 0.46A 3jyrA-5ii5A:
37.7		 3jyrA-5ii5A:
68.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		10 / 12 ASP A3983
LYS A3984
LYS A4011
GLU A4013
GLU A4014
ALA A4032
ASP A4034
ARG A4035
GLU A4080
TRP A4199
 MAL  A4501 (-3.0A)
MAL  A4501 (-2.7A)
None
None
None
MAL  A4501 (-3.3A)
MAL  A4501 (-2.3A)
MAL  A4501 (-3.7A)
MAL  A4501 (-2.7A)
MAL  A4501 ( 3.7A)
 0.98A 3jyrA-5iicA:
56.3		 3jyrA-5iicA:
72.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		10 / 12 ASP A3983
LYS A3984
LYS A4011
GLU A4013
GLU A4014
ALA A4032
ASP A4034
GLU A4080
PRO A4123
TRP A4199
 MAL  A4501 (-3.0A)
MAL  A4501 (-2.7A)
None
None
None
MAL  A4501 (-3.3A)
MAL  A4501 (-2.3A)
MAL  A4501 (-2.7A)
MAL  A4501 (-2.8A)
MAL  A4501 ( 3.7A)
 0.76A 3jyrA-5iicA:
56.3		 3jyrA-5iicA:
72.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2
(Escherichia
coli;
Mus
musculus) 		9 / 12 ASP A-355
LYS A-354
GLU A-325
GLU A-324
ALA A-306
ASP A-304
ARG A-303
GLU A-258
TRP A-139
 MAL  A 701 (-2.7A)
MAL  A 701 (-2.8A)
None
None
MAL  A 701 (-3.3A)
MAL  A 701 (-2.8A)
MAL  A 701 (-3.8A)
MAL  A 701 (-2.9A)
MAL  A 701 ( 4.5A)
 0.78A 3jyrA-5jonA:
62.0		 3jyrA-5jonA:
65.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2
(Escherichia
coli;
Mus
musculus) 		9 / 12 ASP A-355
LYS A-354
GLU A-325
GLU A-324
ALA A-306
ASP A-304
GLU A-258
PRO A-215
TRP A-139
 MAL  A 701 (-2.7A)
MAL  A 701 (-2.8A)
None
None
MAL  A 701 (-3.3A)
MAL  A 701 (-2.8A)
MAL  A 701 (-2.9A)
MAL  A 701 (-3.4A)
MAL  A 701 ( 4.5A)
 0.49A 3jyrA-5jonA:
62.0		 3jyrA-5jonA:
65.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3
(Escherichia
coli;
Mus
musculus) 		9 / 12 ASP A  15
LYS A  16
GLU A  45
GLU A  46
ALA A  64
ASP A  66
ARG A  67
GLU A 112
TRP A 231
 MAL  A 501 (-2.5A)
MAL  A 501 (-2.1A)
None
None
MAL  A 501 (-3.0A)
MAL  A 501 (-2.4A)
MAL  A 501 (-4.0A)
MAL  A 501 (-2.9A)
MAL  A 501 ( 3.3A)
 0.62A 3jyrA-5osqA:
56.7		 3jyrA-5osqA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3
(Escherichia
coli;
Mus
musculus) 		9 / 12 ASP A  15
LYS A  16
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
 MAL  A 501 (-2.5A)
MAL  A 501 (-2.1A)
None
None
MAL  A 501 (-3.0A)
MAL  A 501 (-2.4A)
MAL  A 501 (-2.9A)
MAL  A 501 (-3.0A)
MAL  A 501 ( 3.3A)
 0.30A 3jyrA-5osqA:
56.7		 3jyrA-5osqA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  14
LYS A  15
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
TYR A 341
 MAL  A1501 (-3.2A)
MAL  A1501 (-2.7A)
None
None
MAL  A1501 (-3.5A)
MAL  A1501 (-2.8A)
MAL  A1501 (-3.0A)
MAL  A1501 (-3.6A)
MAL  A1501 ( 4.6A)
None
 0.41A 3jyrA-5tj2A:
61.5		 3jyrA-5tj2A:
85.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
ARG A  68
GLU A 113
TRP A 232
 MAL  A2201 (-3.2A)
MAL  A2201 (-2.7A)
None
None
None
MAL  A2201 (-3.3A)
MAL  A2201 (-2.5A)
MAL  A2201 (-3.9A)
MAL  A2201 (-3.2A)
MAL  A2201 ( 4.8A)
 0.63A 3jyrA-5v6yA:
61.8		 3jyrA-5v6yA:
75.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		10 / 12 ASP A  16
LYS A  17
LYS A  44
GLU A  46
GLU A  47
ALA A  65
ASP A  67
GLU A 113
PRO A 156
TRP A 232
 MAL  A2201 (-3.2A)
MAL  A2201 (-2.7A)
None
None
None
MAL  A2201 (-3.3A)
MAL  A2201 (-2.5A)
MAL  A2201 (-3.2A)
MAL  A2201 (-3.7A)
MAL  A2201 ( 4.8A)
 0.43A 3jyrA-5v6yA:
61.8		 3jyrA-5v6yA:
75.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		10 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
ARG A  67
GLU A 112
TRP A 231
 MAL  A 501 (-2.9A)
MAL  A 501 (-2.8A)
None
EDO  A 503 (-2.9A)
None
MAL  A 501 (-3.3A)
MAL  A 501 (-2.8A)
MAL  A 501 (-3.9A)
MAL  A 501 (-2.9A)
MAL  A 501 ( 4.5A)
 0.75A 3jyrA-5wq6A:
63.3		 3jyrA-5wq6A:
76.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		10 / 12 ASP A  15
LYS A  16
LYS A  43
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
 MAL  A 501 (-2.9A)
MAL  A 501 (-2.8A)
None
EDO  A 503 (-2.9A)
None
MAL  A 501 (-3.3A)
MAL  A 501 (-2.8A)
MAL  A 501 (-2.9A)
MAL  A 501 (-3.4A)
MAL  A 501 ( 4.5A)
 0.42A 3jyrA-5wq6A:
63.3		 3jyrA-5wq6A:
76.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 6dm8 -
(-) 		9 / 12 ASP A-201
LYS A-200
GLU A-171
GLU A-170
ALA A-152
ASP A-150
GLU A-104
PRO A -61
TRP A  15
 MAL  A 402 (-3.1A)
MAL  A 402 (-2.8A)
None
None
MAL  A 402 (-3.4A)
MAL  A 402 (-2.9A)
MAL  A 402 (-3.0A)
MAL  A 402 (-3.5A)
MAL  A 402 (-4.4A)
 0.44A 3jyrA-6dm8A:
60.4		 3jyrA-6dm8A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 456 (-4.4A)
MAL  A 456 (-4.3A)
MAL  A 456 (-4.0A)
MAL  A 456 (-3.8A)
MAL  A 456 ( 4.2A)
MAL  A 456 (-3.9A)
 0.33A 3jyrA-1mg1A:
59.7		 3jyrA-1mg1A:
79.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 7 TYR A 156
MET A 331
TRP A 341
ARG A 345
 MAL  A 456 (-3.8A)
MAL  A 456 ( 4.2A)
MAL  A 456 (-3.9A)
None
 0.83A 3jyrA-1mg1A:
59.7		 3jyrA-1mg1A:
79.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Drosophila
melanogaster;
Escherichia
coli) 		6 / 7 ASN P  11
TRP P  61
GLU P 152
TYR P 154
MET P 329
TRP P 339
 MAL  P 727 (-4.4A)
MAL  P 727 (-4.3A)
MAL  P 727 (-3.6A)
MAL  P 727 (-3.7A)
MAL  P 727 ( 4.3A)
MAL  P 727 (-3.5A)
 0.31A 3jyrA-1r6zP:
61.8		 3jyrA-1r6zP:
72.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Bovine
leukemia
virus;
Escherichia
coli) 		6 / 7 ASN A  38
TRP A  88
GLU A 179
TYR A 181
MET A 356
TRP A 366
 MAL  A1488 (-4.6A)
MAL  A1488 (-4.5A)
MAL  A1488 (-3.6A)
MAL  A1488 (-3.8A)
MAL  A1488 (-4.4A)
MAL  A1488 (-3.8A)
 0.16A 3jyrA-2xz3A:
62.4		 3jyrA-2xz3A:
83.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40
(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
 None
MAL  A 466 (-3.6A)
MAL  A 466 (-3.6A)
MAL  A 466 (-4.2A)
None
MAL  A 466 (-2.6A)
 0.25A 3jyrA-3a3cA:
60.2		 3jyrA-3a3cA:
77.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A-337
TRP A-287
GLU A-196
TYR A-194
MET A -19
TRP A  -9
 MAL  A 126 (-4.0A)
MAL  A 126 (-4.4A)
MAL  A 126 (-3.8A)
MAL  A 126 (-4.1A)
MAL  A 126 ( 4.3A)
MAL  A 126 (-3.7A)
 0.22A 3jyrA-3ehsA:
61.2		 3jyrA-3ehsA:
72.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A-332
TRP A-282
GLU A-191
TYR A-189
MET A -14
TRP A  -4
 MAL  A 194 (-4.1A)
MAL  A 194 (-4.2A)
MAL  A 194 (-3.9A)
MAL  A 194 (-4.1A)
MAL  A 194 ( 4.1A)
MAL  A 194 (-3.6A)
 0.54A 3jyrA-3l2jA:
53.8		 3jyrA-3l2jA:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		6 / 7 ASN A 750
TRP A 800
GLU A 891
TYR A 893
MET A1068
TRP A1078
 MAL  A 600 ( 4.7A)
MAL  A 600 (-4.3A)
MAL  A 600 (-3.8A)
MAL  A 600 (-3.8A)
MAL  A 600 ( 4.2A)
MAL  A 600 (-3.6A)
 0.24A 3jyrA-3mp6A:
62.3		 3jyrA-3mp6A:
63.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		6 / 7 ASN A-358
TRP A-308
GLU A-217
TYR A-215
MET A -40
TRP A -30
 MAL  A 111 (-4.4A)
MAL  A 111 (-4.4A)
MAL  A 111 (-3.7A)
MAL  A 111 (-3.9A)
MAL  A 111 ( 4.4A)
MAL  A 111 (-3.6A)
 0.24A 3jyrA-3n93A:
61.9		 3jyrA-3n93A:
68.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A-336
TRP A-286
GLU A-195
TYR A-193
MET A -18
TRP A  -8
 MAL  A5044 ( 4.7A)
MAL  A5044 (-4.4A)
MAL  A5044 (-3.7A)
MAL  A5044 (-3.8A)
MAL  A5044 ( 4.2A)
MAL  A5044 (-3.6A)
 0.24A 3jyrA-3n94A:
57.3		 3jyrA-3n94A:
79.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		7 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
ARG A 344
 MAL  A1122 ( 4.2A)
MAL  A1122 (-4.4A)
MAL  A1122 (-3.6A)
MAL  A1122 (-3.8A)
MAL  A1122 ( 4.1A)
MAL  A1122 (-3.7A)
None
 0.65A 3jyrA-3oaiA:
62.1		 3jyrA-3oaiA:
69.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 578
TRP A 588
 MAL  A 700 (-4.6A)
MAL  A 700 (-4.5A)
MAL  A 700 (-3.7A)
MAL  A 700 (-3.8A)
MAL  A 700 ( 4.3A)
MAL  A 700 (-3.8A)
 0.15A 3jyrA-3osqA:
45.3		 3jyrA-3osqA:
53.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 579
TRP A 589
 MAL  A 700 ( 4.7A)
MAL  A 700 (-4.4A)
MAL  A 700 (-3.6A)
MAL  A 700 (-3.9A)
MAL  A 700 ( 4.1A)
MAL  A 700 (-3.6A)
 0.38A 3jyrA-3osrA:
63.0		 3jyrA-3osrA:
53.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4b3n MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5
(Escherichia
coli;
Macaca
mulatta) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
 MAL  A 500 ( 4.2A)
MAL  A 500 (-4.3A)
MAL  A 500 (-3.4A)
MAL  A 500 (-3.9A)
MAL  A 500 ( 4.4A)
MAL  A 500 (-3.9A)
 0.41A 3jyrA-4b3nA:
60.8		 3jyrA-4b3nA:
71.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4b3n MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5
(Escherichia
coli;
Macaca
mulatta) 		6 / 7 ASN A  12
TRP A  62
TYR A 155
MET A 330
TRP A 340
ARG A 344
 MAL  A 500 ( 4.2A)
MAL  A 500 (-4.3A)
MAL  A 500 (-3.9A)
MAL  A 500 ( 4.4A)
MAL  A 500 (-3.9A)
None
 0.58A 3jyrA-4b3nA:
60.8		 3jyrA-4b3nA:
71.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
 MAL  A 601 (-4.6A)
MAL  A 601 (-4.3A)
MAL  A 601 (-3.8A)
MAL  A 601 (-3.9A)
MAL  A 601 ( 4.4A)
MAL  A 601 (-3.7A)
 0.21A 3jyrA-4egcA:
55.6		 3jyrA-4egcA:
63.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 501 ( 4.8A)
MAL  A 501 (-4.4A)
MAL  A 501 (-3.7A)
MAL  A 501 (-3.8A)
MAL  A 501 (-4.2A)
MAL  A 501 (-3.7A)
 0.20A 3jyrA-4ifpA:
61.5		 3jyrA-4ifpA:
81.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		5 / 7 TRP A  63
TYR A 156
MET A 331
TRP A 341
ARG A 345
 MAL  A 501 (-4.4A)
MAL  A 501 (-3.8A)
MAL  A 501 (-4.2A)
MAL  A 501 (-3.7A)
None
 0.68A 3jyrA-4ifpA:
61.5		 3jyrA-4ifpA:
81.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 501 (-4.2A)
MAL  A 501 (-4.4A)
MAL  A 501 (-3.6A)
MAL  A 501 (-4.0A)
MAL  A 501 (-4.6A)
MAL  A 501 (-3.8A)
 0.18A 3jyrA-4ikmA:
61.7		 3jyrA-4ikmA:
77.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 501 (-4.4A)
MAL  A 501 (-4.5A)
MAL  A 501 (-3.6A)
MAL  A 501 (-3.9A)
MAL  A 501 ( 4.3A)
MAL  A 501 (-3.7A)
 0.23A 3jyrA-4kv3A:
61.6		 3jyrA-4kv3A:
74.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  14
TRP A  64
GLU A 155
TYR A 157
MET A 332
TRP A 342
 MAL  A1201 (-3.9A)
MAL  A1201 (-4.3A)
MAL  A1201 (-3.6A)
MAL  A1201 (-3.9A)
MAL  A1201 ( 4.3A)
MAL  A1201 (-3.6A)
 0.27A 3jyrA-4my2A:
62.0		 3jyrA-4my2A:
77.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		6 / 7 ASN A  14
TRP A  64
GLU A 155
TYR A 157
MET A 332
TRP A 342
 MAL  A1301 (-4.0A)
MAL  A1301 (-4.5A)
MAL  A1301 (-3.2A)
MAL  A1301 (-4.0A)
MAL  A1301 ( 4.2A)
MAL  A1301 (-3.6A)
 0.30A 3jyrA-4nufA:
55.4		 3jyrA-4nufA:
58.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Clostridioides
difficile;
Escherichia
coli) 		7 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
ARG A 344
 MAL  A 601 (-4.5A)
MAL  A 601 (-4.5A)
MAL  A 601 (-3.6A)
MAL  A 601 (-3.9A)
MAL  A 601 ( 4.3A)
MAL  A 601 (-3.8A)
None
 0.30A 3jyrA-4pe2A:
54.3		 3jyrA-4pe2A:
72.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA
(Escherichia
coli;
Mycobacterium
tuberculosis) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 601 ( 4.6A)
MAL  A 601 (-4.3A)
MAL  A 601 (-3.6A)
MAL  A 601 (-3.9A)
MAL  A 601 ( 4.4A)
MAL  A 601 (-3.6A)
 0.24A 3jyrA-4qvhA:
62.0		 3jyrA-4qvhA:
61.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  14
GLU A 155
TYR A 157
MET A 332
TRP A 342
ARG A 346
 MAL  A2201 (-4.6A)
MAL  A2201 (-3.7A)
MAL  A2201 (-3.9A)
MAL  A2201 ( 4.3A)
MAL  A2201 (-3.7A)
None
 0.88A 3jyrA-4rwfA:
61.9		 3jyrA-4rwfA:
61.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  14
TRP A  64
GLU A 155
TYR A 157
MET A 332
TRP A 342
 MAL  A2201 (-4.6A)
MAL  A2201 (-4.3A)
MAL  A2201 (-3.7A)
MAL  A2201 (-3.9A)
MAL  A2201 ( 4.3A)
MAL  A2201 (-3.7A)
 0.17A 3jyrA-4rwfA:
61.9		 3jyrA-4rwfA:
61.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN
(Escherichia
coli;
Homo
sapiens) 		7 / 7 ASN A  36
TRP A  86
GLU A 177
TYR A 179
MET A 354
TRP A 364
ARG A 368
 None
MAL  A 801 (-4.1A)
MAL  A 801 (-3.0A)
MAL  A 801 (-2.9A)
MAL  A 801 ( 3.8A)
MAL  A 801 (-3.0A)
None
 0.75A 3jyrA-4wrnA:
59.5		 3jyrA-4wrnA:
48.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB
(Escherichia
coli;
Staphylococcus
aureus) 		6 / 7 ASN A  18
TRP A  68
GLU A 159
TYR A 161
MET A 336
TRP A 346
 MAL  A 601 (-4.4A)
MAL  A 601 (-4.4A)
MAL  A 601 (-3.6A)
MAL  A 601 (-3.9A)
MAL  A 601 ( 4.3A)
MAL  A 601 (-3.7A)
 0.24A 3jyrA-4wviA:
61.6		 3jyrA-4wviA:
61.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		6 / 7 ASN A  14
TRP A  64
GLU A 155
TYR A 157
MET A 332
TRP A 342
 MAL  A1401 (-4.6A)
MAL  A1401 (-4.5A)
MAL  A1401 (-3.7A)
MAL  A1401 (-3.8A)
MAL  A1401 ( 4.4A)
MAL  A1401 (-3.7A)
 0.27A 3jyrA-4xaiA:
62.1		 3jyrA-4xaiA:
77.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  14
TRP A  64
GLU A 155
TYR A 157
MET A 332
TRP A 342
 MAL  A1900 (-4.6A)
MAL  A1900 (-4.0A)
MAL  A1900 (-4.5A)
MAL  A1900 (-4.2A)
MAL  A1900 ( 4.5A)
MAL  A1900 ( 4.0A)
 0.31A 3jyrA-4xajA:
61.9		 3jyrA-4xajA:
58.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
 MAL  A 901 ( 4.9A)
MAL  A 901 (-4.4A)
MAL  A 901 (-3.7A)
MAL  A 901 (-3.8A)
MAL  A 901 ( 4.4A)
MAL  A 901 (-3.6A)
 0.44A 3jyrA-5azaA:
58.0		 3jyrA-5azaA:
42.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Acinetobacter
nosocomialis;
Escherichia
coli) 		7 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
ARG A 344
 MAL  A1201 (-4.5A)
MAL  A1201 (-4.4A)
MAL  A1201 (-3.6A)
MAL  A1201 (-3.9A)
MAL  A1201 (-4.3A)
MAL  A1201 (-3.7A)
None
 0.79A 3jyrA-5cfvA:
55.2		 3jyrA-5cfvA:
72.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19
(Escherichia
coli;
Tetrahymena
thermophila) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
 SO4  A 602 (-3.5A)
MAL  A 601 (-4.3A)
MAL  A 601 ( 3.7A)
MAL  A 601 (-4.0A)
MAL  A 601 ( 4.3A)
MAL  A 601 (-3.6A)
 0.51A 3jyrA-5dfmA:
60.6		 3jyrA-5dfmA:
69.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5edu MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HISTONE DEACETYLASE
6 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		7 / 7 ASN B 120
TRP B 170
GLU B 261
TYR B 263
MET B 438
TRP B 448
ARG B 452
 MAL  B2505 (-4.4A)
MAL  B2505 (-4.3A)
MAL  B2505 (-3.4A)
MAL  B2505 (-4.1A)
MAL  B2505 ( 4.5A)
MAL  B2505 (-3.8A)
None
 0.36A 3jyrA-5eduB:
60.0		 3jyrA-5eduB:
47.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		7 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
ARG A 345
 MAL  A 501 ( 4.9A)
MAL  A 501 (-4.8A)
MAL  A 501 (-3.8A)
MAL  A 501 (-4.2A)
MAL  A 501 ( 4.6A)
MAL  A 501 ( 4.0A)
None
 0.60A 3jyrA-5gppA:
44.2		 3jyrA-5gppA:
78.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 501 (-4.4A)
MAL  A 501 (-4.4A)
MAL  A 501 (-3.7A)
MAL  A 501 (-3.9A)
MAL  A 501 ( 4.4A)
MAL  A 501 (-3.7A)
 0.17A 3jyrA-5gpqA:
62.4		 3jyrA-5gpqA:
78.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		6 / 7 ASN A  13
TRP A  63
TYR A 156
MET A 331
TRP A 341
ARG A 345
 MAL  A 501 (-4.4A)
MAL  A 501 (-4.4A)
MAL  A 501 (-3.9A)
MAL  A 501 ( 4.4A)
MAL  A 501 (-3.7A)
None
 0.58A 3jyrA-5gpqA:
62.4		 3jyrA-5gpqA:
78.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		7 / 7 ASN A 379
TRP A 429
GLU A 520
TYR A 522
MET A 697
TRP A 707
ARG A 711
 MAL  A1001 (-4.1A)
MAL  A1001 (-4.3A)
MAL  A1001 (-3.3A)
MAL  A1001 (-4.0A)
MAL  A1001 ( 4.4A)
MAL  A1001 (-4.0A)
None
 0.72A 3jyrA-5hzvA:
61.5		 3jyrA-5hzvA:
81.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  67
GLU A 208
TYR A 210
MET A 385
TRP A 395
ARG A 399
 MAL  A 803 ( 4.4A)
MAL  A 803 (-3.5A)
MAL  A 803 (-3.0A)
MAL  A 803 ( 3.5A)
MAL  A 803 ( 3.0A)
None
 0.82A 3jyrA-5hzwA:
59.8		 3jyrA-5hzwA:
58.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  67
TRP A 117
GLU A 208
TYR A 210
MET A 385
TRP A 395
 MAL  A 803 ( 4.4A)
MAL  A 803 (-3.6A)
MAL  A 803 (-3.5A)
MAL  A 803 (-3.0A)
MAL  A 803 ( 3.5A)
MAL  A 803 ( 3.0A)
 0.43A 3jyrA-5hzwA:
59.8		 3jyrA-5hzwA:
58.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		6 / 7 ASN A3679
TRP A3729
GLU A3820
TYR A3822
MET A3997
TRP A4007
 MAL  A4201 (-4.6A)
MAL  A4201 (-3.7A)
MAL  A4201 (-3.2A)
MAL  A4201 (-2.8A)
MAL  A4201 ( 3.5A)
MAL  A4201 (-2.6A)
 0.20A 3jyrA-5ii5A:
37.7		 3jyrA-5ii5A:
68.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		6 / 7 ASN A3981
TRP A4031
GLU A4122
TYR A4124
MET A4299
TRP A4309
 MAL  A4501 (-4.0A)
MAL  A4501 (-3.8A)
MAL  A4501 (-3.8A)
MAL  A4501 (-3.0A)
MAL  A4501 ( 3.4A)
MAL  A4501 ( 3.0A)
 0.35A 3jyrA-5iicA:
56.3		 3jyrA-5iicA:
72.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2
(Escherichia
coli;
Mus
musculus) 		6 / 7 ASN A-357
TRP A-307
GLU A-216
TYR A-214
MET A -39
TRP A -29
 MAL  A 701 (-4.5A)
MAL  A 701 (-4.3A)
MAL  A 701 (-3.6A)
MAL  A 701 (-3.9A)
MAL  A 701 ( 4.3A)
MAL  A 701 (-3.7A)
 0.25A 3jyrA-5jonA:
62.0		 3jyrA-5jonA:
65.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3
(Escherichia
coli;
Mus
musculus) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 501 (-4.3A)
MAL  A 501 (-3.8A)
MAL  A 501 (-3.4A)
MAL  A 501 (-2.7A)
MAL  A 501 ( 3.5A)
MAL  A 501 (-2.6A)
 0.25A 3jyrA-5osqA:
56.7		 3jyrA-5osqA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
 MAL  A1501 (-4.3A)
MAL  A1501 (-4.4A)
MAL  A1501 (-3.5A)
MAL  A1501 (-3.9A)
MAL  A1501 ( 4.5A)
MAL  A1501 (-3.8A)
 0.14A 3jyrA-5tj2A:
61.5		 3jyrA-5tj2A:
85.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		6 / 7 ASN A  14
TRP A  64
GLU A 155
TYR A 157
MET A 332
TRP A 342
 MAL  A2201 (-4.1A)
MAL  A2201 (-4.5A)
MAL  A2201 (-3.7A)
MAL  A2201 (-3.9A)
MAL  A2201 ( 4.2A)
MAL  A2201 (-3.7A)
 0.28A 3jyrA-5v6yA:
61.8		 3jyrA-5v6yA:
75.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 EDO  A 503 (-3.4A)
MAL  A 501 (-4.5A)
MAL  A 501 (-3.7A)
MAL  A 501 (-3.8A)
MAL  A 501 (-4.4A)
MAL  A 501 (-3.7A)
 0.18A 3jyrA-5wq6A:
63.3		 3jyrA-5wq6A:
76.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		7 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
ARG A 345
 MAL  A 501 ( 3.7A)
MAL  A 501 (-3.5A)
MAL  A 501 (-3.6A)
MAL  A 501 (-2.9A)
MAL  A 501 ( 3.7A)
MAL  A 501 (-2.7A)
None
 0.70A 3jyrA-5z0rA:
37.2		 3jyrA-5z0rA:
60.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 6dm8 -
(-) 		6 / 7 ASN A-203
TRP A-153
GLU A -62
TYR A -60
MET A 115
TRP A 125
 MAL  A 402 ( 4.7A)
MAL  A 402 (-4.1A)
MAL  A 402 (-3.7A)
MAL  A 402 (-4.1A)
MAL  A 402 ( 4.8A)
MAL  A 402 (-3.7A)
 0.48A 3jyrA-6dm8A:
60.4		 3jyrA-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Escherichia
coli;
Bovine
leukemia
virus) 		5 / 12 ALA A 188
LEU A 186
ILE A 374
ARG A 370
LEU A 177
 EDO  A1490 ( 3.7A)
None
None
MAL  A1488 (-4.3A)
None
 0.99A 3mb5A-2xz3A:
undetectable		 3mb5A-2xz3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA A 163
LEU A 161
ILE A 349
ARG A 345
LEU A 152
 None
None
None
MAL  A 501 (-4.2A)
None
 1.03A 3mb5A-4ikmA:
undetectable		 3mb5A-4ikmA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Bacillus
cytotoxicus) 		5 / 9 LEU A  88
GLY A  99
ILE A  98
ILE A  84
ILE A  85
 None
MAL  A 501 (-3.3A)
MAL  A 501 (-4.8A)
None
None
 0.95A 3s56B-3k4hA:
undetectable		 3s56B-3k4hA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-188
GLY A -44
LEU A -45
GLU A-233
ASP A-330
 MAL  A 194 (-4.4A)
None
None
MAL  A 194 (-2.9A)
MAL  A 194 (-2.9A)
 1.24A 3tbgA-3l2jA:
undetectable		 3tbgA-3l2jA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 456 (-2.6A)
None
 0.89A 3tbgB-1mg1A:
0.0		 3tbgB-1mg1A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Drosophila
melanogaster;
Escherichia
coli) 		5 / 12 PHE P 155
GLY P 299
LEU P 298
GLU P 110
ALA P 230
 None
None
None
MAL  P 727 (-2.8A)
None
 0.86A 3tbgB-1r6zP:
0.0		 3tbgB-1r6zP:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Bovine
leukemia
virus;
Escherichia
coli) 		5 / 12 PHE A 182
GLY A 326
LEU A 325
GLU A 137
ALA A 257
 None
None
None
MAL  A1488 (-2.9A)
None
 0.87A 3tbgB-2xz3A:
undetectable		 3tbgB-2xz3A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40
(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 466 (-3.1A)
None
 0.89A 3tbgB-3a3cA:
undetectable		 3tbgB-3a3cA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-193
GLY A -49
LEU A -50
GLU A-238
ALA A-118
 None
None
None
MAL  A 126 (-2.6A)
None
 0.83A 3tbgB-3ehsA:
undetectable		 3tbgB-3ehsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-188
GLY A -44
LEU A -45
GLU A-233
ALA A-113
 MAL  A 194 (-4.4A)
None
None
MAL  A 194 (-2.9A)
None
 0.86A 3tbgB-3l2jA:
undetectable		 3tbgB-3l2jA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		5 / 12 PHE A 894
GLY A1038
LEU A1037
GLU A 849
ALA A 969
 MAL  A 600 (-4.8A)
None
None
MAL  A 600 (-2.9A)
None
 0.91A 3tbgB-3mp6A:
undetectable		 3tbgB-3mp6A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 PHE A-214
GLY A -70
LEU A -71
GLU A-259
ALA A-139
 None
None
None
MAL  A 111 (-3.4A)
None
 0.86A 3tbgB-3n93A:
undetectable		 3tbgB-3n93A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-192
GLY A -48
LEU A -49
GLU A-237
ALA A-117
 MAL  A5044 ( 4.9A)
None
None
MAL  A5044 (-2.9A)
None
 0.81A 3tbgB-3n94A:
undetectable		 3tbgB-3n94A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A1122 (-2.9A)
None
 0.83A 3tbgB-3oaiA:
undetectable		 3tbgB-3oaiA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 548
LEU A 547
GLU A 111
ALA A 479
 MAL  A 700 ( 4.9A)
None
None
MAL  A 700 (-2.9A)
None
 0.86A 3tbgB-3osqA:
undetectable		 3tbgB-3osqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 MAL  A 700 (-4.9A)
None
None
MAL  A 700 (-3.0A)
None
 0.86A 3tbgB-3osrA:
undetectable		 3tbgB-3osrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 601 (-2.9A)
None
 0.84A 3tbgB-4egcA:
undetectable		 3tbgB-4egcA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-3.0A)
None
 0.82A 3tbgB-4ifpA:
undetectable		 3tbgB-4ifpA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
TYI  A 308 ( 4.9A)
MAL  A 501 (-2.9A)
TYI  A 211 ( 3.8A)
 0.83A 3tbgB-4ikmA:
undetectable		 3tbgB-4ikmA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-3.0A)
None
 0.83A 3tbgB-4kv3A:
undetectable		 3tbgB-4kv3A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 None
None
None
MAL  A1201 (-3.1A)
None
 0.83A 3tbgB-4my2A:
undetectable		 3tbgB-4my2A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Clostridioides
difficile;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 601 (-3.1A)
None
 0.85A 3tbgB-4pe2A:
undetectable		 3tbgB-4pe2A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA
(Escherichia
coli;
Mycobacterium
tuberculosis) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 601 (-2.8A)
None
 0.85A 3tbgB-4qvhA:
undetectable		 3tbgB-4qvhA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 None
None
None
MAL  A2201 (-3.0A)
None
 0.86A 3tbgB-4rwfA:
undetectable		 3tbgB-4rwfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 180
GLY A 324
LEU A 323
GLU A 135
ALA A 255
 None
None
None
MAL  A 801 (-2.8A)
None
 0.81A 3tbgB-4wrnA:
undetectable		 3tbgB-4wrnA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 PHE A 162
GLY A 306
LEU A 305
GLU A 117
ALA A 237
 None
None
None
MAL  A 601 (-2.9A)
None
 0.86A 3tbgB-4wviA:
undetectable		 3tbgB-4wviA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 None
None
None
MAL  A1900 (-2.8A)
None
 0.84A 3tbgB-4xajA:
undetectable		 3tbgB-4xajA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 901 (-3.1A)
None
 0.87A 3tbgB-5azaA:
undetectable		 3tbgB-5azaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Acinetobacter
nosocomialis;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A1201 (-3.0A)
None
 0.85A 3tbgB-5cfvA:
undetectable		 3tbgB-5cfvA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19
(Escherichia
coli;
Tetrahymena
thermophila) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 601 (-3.0A)
None
 0.83A 3tbgB-5dfmA:
undetectable		 3tbgB-5dfmA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-2.9A)
None
 0.84A 3tbgB-5gpqA:
undetectable		 3tbgB-5gpqA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 523
GLY A 667
LEU A 666
GLU A 478
ALA A 598
 None
None
None
MAL  A1001 (-3.1A)
None
 0.81A 3tbgB-5hzvA:
undetectable		 3tbgB-5hzvA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 211
GLY A 355
LEU A 354
GLU A 166
ALA A 286
 MAL  A 803 ( 4.5A)
None
None
MAL  A 803 (-2.7A)
None
 0.82A 3tbgB-5hzwA:
undetectable		 3tbgB-5hzwA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		5 / 12 PHE A3823
GLY A3967
LEU A3966
GLU A3778
ALA A3898
 MAL  A4201 ( 4.2A)
None
None
MAL  A4201 (-3.0A)
None
 0.84A 3tbgB-5ii5A:
undetectable		 3tbgB-5ii5A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		5 / 12 PHE A4125
GLY A4269
LEU A4268
GLU A4080
ALA A4200
 MAL  A4501 ( 4.7A)
None
None
MAL  A4501 (-2.7A)
None
 0.81A 3tbgB-5iicA:
undetectable		 3tbgB-5iicA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2
(Escherichia
coli;
Mus
musculus) 		5 / 12 PHE A-213
GLY A -69
LEU A -70
GLU A-258
ALA A-138
 MAL  A 701 ( 4.9A)
None
None
MAL  A 701 (-2.9A)
None
 0.86A 3tbgB-5jonA:
undetectable		 3tbgB-5jonA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3
(Escherichia
coli;
Mus
musculus) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 MAL  A 501 ( 4.4A)
None
None
MAL  A 501 (-2.9A)
None
 0.86A 3tbgB-5osqA:
undetectable		 3tbgB-5osqA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A1501 (-3.0A)
None
 0.83A 3tbgB-5tj2A:
undetectable		 3tbgB-5tj2A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 MAL  A2201 (-4.8A)
None
None
MAL  A2201 (-3.2A)
None
 0.81A 3tbgB-5v6yA:
undetectable		 3tbgB-5v6yA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-2.9A)
None
 0.84A 3tbgB-5wq6A:
undetectable		 3tbgB-5wq6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 6dm8 -
(-) 		5 / 12 PHE A -59
GLY A  85
LEU A  84
GLU A-104
ALA A  16
 None
None
None
MAL  A 402 (-3.0A)
None
 0.83A 3tbgB-6dm8A:
undetectable		 3tbgB-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-188
GLY A -44
LEU A -45
GLU A-233
ASP A-330
 MAL  A 194 (-4.4A)
None
None
MAL  A 194 (-2.9A)
MAL  A 194 (-2.9A)
 1.24A 3tbgC-3l2jA:
undetectable		 3tbgC-3l2jA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 456 (-2.6A)
None
 0.87A 3tbgD-1mg1A:
0.0		 3tbgD-1mg1A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Drosophila
melanogaster;
Escherichia
coli) 		5 / 12 PHE P 155
GLY P 299
LEU P 298
GLU P 110
ALA P 230
 None
None
None
MAL  P 727 (-2.8A)
None
 0.85A 3tbgD-1r6zP:
0.0		 3tbgD-1r6zP:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Bovine
leukemia
virus;
Escherichia
coli) 		5 / 12 PHE A 182
GLY A 326
LEU A 325
GLU A 137
ALA A 257
 None
None
None
MAL  A1488 (-2.9A)
None
 0.85A 3tbgD-2xz3A:
undetectable		 3tbgD-2xz3A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40
(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 466 (-3.1A)
None
 0.88A 3tbgD-3a3cA:
undetectable		 3tbgD-3a3cA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-193
GLY A -49
LEU A -50
GLU A-238
ALA A-118
 None
None
None
MAL  A 126 (-2.6A)
None
 0.82A 3tbgD-3ehsA:
undetectable		 3tbgD-3ehsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-188
GLY A -44
LEU A -45
GLU A-233
ALA A-113
 MAL  A 194 (-4.4A)
None
None
MAL  A 194 (-2.9A)
None
 0.84A 3tbgD-3l2jA:
undetectable		 3tbgD-3l2jA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		5 / 12 PHE A 894
GLY A1038
LEU A1037
GLU A 849
ALA A 969
 MAL  A 600 (-4.8A)
None
None
MAL  A 600 (-2.9A)
None
 0.89A 3tbgD-3mp6A:
undetectable		 3tbgD-3mp6A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 PHE A-214
GLY A -70
LEU A -71
GLU A-259
ALA A-139
 None
None
None
MAL  A 111 (-3.4A)
None
 0.84A 3tbgD-3n93A:
undetectable		 3tbgD-3n93A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A-192
GLY A -48
LEU A -49
GLU A-237
ALA A-117
 MAL  A5044 ( 4.9A)
None
None
MAL  A5044 (-2.9A)
None
 0.79A 3tbgD-3n94A:
undetectable		 3tbgD-3n94A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A1122 (-2.9A)
None
 0.82A 3tbgD-3oaiA:
undetectable		 3tbgD-3oaiA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 548
LEU A 547
GLU A 111
ALA A 479
 MAL  A 700 ( 4.9A)
None
None
MAL  A 700 (-2.9A)
None
 0.84A 3tbgD-3osqA:
undetectable		 3tbgD-3osqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 MAL  A 700 (-4.9A)
None
None
MAL  A 700 (-3.0A)
None
 0.84A 3tbgD-3osrA:
undetectable		 3tbgD-3osrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 601 (-2.9A)
None
 0.83A 3tbgD-4egcA:
undetectable		 3tbgD-4egcA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-3.0A)
None
 0.80A 3tbgD-4ifpA:
undetectable		 3tbgD-4ifpA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
TYI  A 308 ( 4.9A)
MAL  A 501 (-2.9A)
TYI  A 211 ( 3.8A)
 0.82A 3tbgD-4ikmA:
undetectable		 3tbgD-4ikmA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-3.0A)
None
 0.81A 3tbgD-4kv3A:
undetectable		 3tbgD-4kv3A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 None
None
None
MAL  A1201 (-3.1A)
None
 0.82A 3tbgD-4my2A:
undetectable		 3tbgD-4my2A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Clostridioides
difficile;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 601 (-3.1A)
None
 0.83A 3tbgD-4pe2A:
undetectable		 3tbgD-4pe2A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA
(Escherichia
coli;
Mycobacterium
tuberculosis) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 601 (-2.8A)
None
 0.83A 3tbgD-4qvhA:
undetectable		 3tbgD-4qvhA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 None
None
None
MAL  A2201 (-3.0A)
None
 0.84A 3tbgD-4rwfA:
undetectable		 3tbgD-4rwfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 180
GLY A 324
LEU A 323
GLU A 135
ALA A 255
 None
None
None
MAL  A 801 (-2.8A)
None
 0.79A 3tbgD-4wrnA:
undetectable		 3tbgD-4wrnA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 PHE A 162
GLY A 306
LEU A 305
GLU A 117
ALA A 237
 None
None
None
MAL  A 601 (-2.9A)
None
 0.84A 3tbgD-4wviA:
undetectable		 3tbgD-4wviA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 None
None
None
MAL  A1900 (-2.8A)
None
 0.82A 3tbgD-4xajA:
undetectable		 3tbgD-4xajA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 901 (-3.1A)
None
 0.86A 3tbgD-5azaA:
undetectable		 3tbgD-5azaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Acinetobacter
nosocomialis;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A1201 (-3.0A)
None
 0.83A 3tbgD-5cfvA:
undetectable		 3tbgD-5cfvA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19
(Escherichia
coli;
Tetrahymena
thermophila) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A 601 (-3.0A)
None
 0.82A 3tbgD-5dfmA:
undetectable		 3tbgD-5dfmA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-3.3A)
None
 0.98A 3tbgD-5gppA:
undetectable		 3tbgD-5gppA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-2.9A)
None
 0.83A 3tbgD-5gpqA:
undetectable		 3tbgD-5gpqA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 523
GLY A 667
LEU A 666
GLU A 478
ALA A 598
 None
None
None
MAL  A1001 (-3.1A)
None
 0.80A 3tbgD-5hzvA:
undetectable		 3tbgD-5hzvA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 211
GLY A 355
LEU A 354
GLU A 166
ALA A 286
 MAL  A 803 ( 4.5A)
None
None
MAL  A 803 (-2.7A)
None
 0.80A 3tbgD-5hzwA:
undetectable		 3tbgD-5hzwA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		5 / 12 PHE A3823
GLY A3967
LEU A3966
GLU A3778
ALA A3898
 MAL  A4201 ( 4.2A)
None
None
MAL  A4201 (-3.0A)
None
 0.82A 3tbgD-5ii5A:
undetectable		 3tbgD-5ii5A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		5 / 12 PHE A4125
GLY A4269
LEU A4268
GLU A4080
ALA A4200
 MAL  A4501 ( 4.7A)
None
None
MAL  A4501 (-2.7A)
None
 0.79A 3tbgD-5iicA:
undetectable		 3tbgD-5iicA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2
(Escherichia
coli;
Mus
musculus) 		5 / 12 PHE A-213
GLY A -69
LEU A -70
GLU A-258
ALA A-138
 MAL  A 701 ( 4.9A)
None
None
MAL  A 701 (-2.9A)
None
 0.84A 3tbgD-5jonA:
undetectable		 3tbgD-5jonA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3
(Escherichia
coli;
Mus
musculus) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 MAL  A 501 ( 4.4A)
None
None
MAL  A 501 (-2.9A)
None
 0.85A 3tbgD-5osqA:
undetectable		 3tbgD-5osqA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 None
None
None
MAL  A1501 (-3.0A)
None
 0.81A 3tbgD-5tj2A:
undetectable		 3tbgD-5tj2A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 158
GLY A 302
LEU A 301
GLU A 113
ALA A 233
 MAL  A2201 (-4.8A)
None
None
MAL  A2201 (-3.2A)
None
 0.80A 3tbgD-5v6yA:
undetectable		 3tbgD-5v6yA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-2.9A)
None
 0.83A 3tbgD-5wq6A:
undetectable		 3tbgD-5wq6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 6dm8 -
(-) 		5 / 12 PHE A -59
GLY A  85
LEU A  84
GLU A-104
ALA A  16
 None
None
None
MAL  A 402 (-3.0A)
None
 0.82A 3tbgD-6dm8A:
undetectable		 3tbgD-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		4 / 6 GLY A 261
GLU A 112
ASP A  15
ASP A  66
 MAL  A 501 ( 4.8A)
MAL  A 501 (-2.6A)
None
MAL  A 501 (-3.0A)
 1.02A 3vywC-5z0rA:
undetectable		 3vywC-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 8 HIS A 101
LEU A  63
THR A  62
HIS A 177
 MAL  A 500 (-4.4A)
MAL  A 500 ( 4.5A)
MAL  A 500 (-4.1A)
MAL  A 500 (-4.0A)
 1.02A 3w6hA-4bzgA:
undetectable		 3w6hA-4bzgA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)
(Bacillus
cereus) 		5 / 12 GLU A 355
GLU A 358
PHE A 359
TYR A 369
PHE A 237
 MAL  A 501 (-2.5A)
None
None
None
None
 1.32A 4a97F-6bvgA:
0.0
4a97J-6bvgA:
0.0		 4a97F-6bvgA:
12.29
4a97J-6bvgA:
12.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BZF_B_ACTB502_0
(ALDOSE 1-EPIMERASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 4 HIS A 101
HIS A 177
ASP A 230
TYR A 271
 MAL  A 500 (-4.4A)
MAL  A 500 (-4.0A)
MAL  A 500 (-2.7A)
MAL  A 500 (-3.9A)
 0.16A 4bzfB-4bzgA:
56.7		 4bzfB-4bzgA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)
(Bacillus
cereus) 		5 / 12 THR A 250
PHE A 393
VAL A  20
ALA A 392
GLN A 310
 None
MAL  A 501 (-4.6A)
None
None
MAL  A 501 (-4.1A)
 1.07A 4df3A-6bvgA:
undetectable		 4df3A-6bvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)
(Bacillus
cereus) 		5 / 12 THR A 250
PHE A 393
VAL A  20
ALA A 392
GLN A 310
 None
MAL  A 501 (-4.6A)
None
None
MAL  A 501 (-4.1A)
 1.09A 4df3B-6bvgA:
undetectable		 4df3B-6bvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 6 GLU A  93
ILE A  91
ASN A  92
VAL A 292
 MAL  A 500 (-3.7A)
None
None
None
 1.03A 4ejwB-4bzgA:
undetectable		 4ejwB-4bzgA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 4hw8 BACTERIAL
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, PUTATIVE
(Staphylococcus
aureus) 		3 / 3 ARG A 306
TYR A 201
ASN A 196
 None
None
MAL  A 506 (-3.7A)
 0.73A 4ffwB-4hw8A:
undetectable		 4ffwB-4hw8A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1obb ALPHA-GLUCOSIDASE
(Thermotoga
maritima) 		4 / 8 GLY A  12
TYR A 296
LEU A 300
VAL A 303
 NAD  A 500 (-3.0A)
MAL  A 900 (-4.2A)
NAD  A 500 ( 4.9A)
None
 0.49A 4fgzA-1obbA:
4.0		 4fgzA-1obbA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1obb ALPHA-GLUCOSIDASE
(Thermotoga
maritima) 		4 / 8 GLY A  12
TYR A 296
LEU A 300
VAL A 303
 NAD  A 500 (-3.0A)
MAL  A 900 (-4.2A)
NAD  A 500 ( 4.9A)
None
 0.50A 4fgzB-1obbA:
4.0		 4fgzB-1obbA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)
(Bacillus
cereus) 		3 / 3 TYR A 227
ARG A 232
HIS A 240
 None
MAL  A 501 (-3.0A)
MAL  A 501 (-3.9A)
 1.25A 4fubA-6bvgA:
undetectable		 4fubA-6bvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 12 LEU A 209
LEU A 218
PHE A 233
PRO A 213
ASP A 230
 None
None
None
None
MAL  A 500 (-2.7A)
 1.47A 4j7xJ-4bzgA:
undetectable		 4j7xJ-4bzgA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)
(Bacillus
cereus) 		5 / 7 ARG A 305
SER A 215
GLY A 309
GLY A 228
GLU A 231
 None
None
None
None
MAL  A 501 (-3.6A)
 1.21A 4koeA-6bvgA:
undetectable
4koeB-6bvgA:
undetectable
4koeD-6bvgA:
undetectable		 4koeA-6bvgA:
8.88
4koeB-6bvgA:
8.88
4koeD-6bvgA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19
(Escherichia
coli;
Tetrahymena
thermophila) 		4 / 7 PRO A 331
ALA A 168
LYS A 256
TYR A 155
 None
None
None
MAL  A 601 (-4.0A)
 1.06A 4lb2A-5dfmA:
undetectable		 4lb2A-5dfmA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		4 / 7 PRO A 332
ALA A 169
LYS A 257
TYR A 156
 None
None
None
MAL  A 501 (-4.2A)
 1.06A 4lb2A-5gppA:
undetectable		 4lb2A-5gppA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 456 (-3.4A)
 0.98A 4n48A-1mg1A:
undetectable		 4n48A-1mg1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Escherichia
coli;
Drosophila
melanogaster) 		4 / 5 ASN P 266
ALA P  50
GLY P  55
ASP P  13
 None
None
None
MAL  P 727 (-3.0A)
 0.97A 4n48A-1r6zP:
undetectable		 4n48A-1r6zP:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Escherichia
coli;
Bovine
leukemia
virus) 		4 / 5 ASN A 293
ALA A  77
GLY A  82
ASP A  40
 EDO  A1494 ( 4.1A)
None
EDO  A1494 (-4.4A)
MAL  A1488 (-3.0A)
 0.95A 4n48A-2xz3A:
undetectable		 4n48A-2xz3A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		4 / 5 ASN A1005
ALA A 789
GLY A 794
ASP A 752
 None
None
None
MAL  A 600 (-2.9A)
 0.95A 4n48A-3mp6A:
undetectable		 4n48A-3mp6A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 5 ASN A-103
ALA A-319
GLY A-314
ASP A-356
 None
None
None
MAL  A 111 (-3.1A)
 0.98A 4n48A-3n93A:
undetectable		 4n48A-3n93A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A -81
ALA A-297
GLY A-292
ASP A-334
 None
None
None
MAL  A5044 (-3.1A)
 1.00A 4n48A-3n94A:
undetectable		 4n48A-3n94A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 5 ASN A 515
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A 700 (-2.8A)
 0.96A 4n48A-3osqA:
undetectable		 4n48A-3osqA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A 700 (-3.1A)
 0.99A 4n48A-3osrA:
undetectable		 4n48A-3osrA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4egc MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HOMEOBOX PROTEIN
SIX1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A 601 (-2.9A)
 0.95A 4n48A-4egcA:
undetectable		 4n48A-4egcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 501 (-3.0A)
 0.96A 4n48A-4ifpA:
undetectable		 4n48A-4ifpA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 501 (-3.1A)
 1.00A 4n48A-4ikmA:
undetectable		 4n48A-4ikmA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 269
ALA A  53
GLY A  58
ASP A  16
 None
None
None
MAL  A1201 (-3.0A)
 0.96A 4n48A-4my2A:
undetectable		 4n48A-4my2A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Escherichia
coli;
Clostridioides
difficile) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A 601 (-3.1A)
 0.98A 4n48A-4pe2A:
undetectable		 4n48A-4pe2A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA
(Escherichia
coli;
Mycobacterium
tuberculosis) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 601 (-3.1A)
 1.00A 4n48A-4qvhA:
undetectable		 4n48A-4qvhA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 269
ALA A  53
GLY A  58
ASP A  16
 None
None
None
MAL  A2201 (-3.0A)
 0.97A 4n48A-4rwfA:
undetectable		 4n48A-4rwfA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		4 / 5 ASN A 269
ALA A  53
GLY A  58
ASP A  16
 None
None
None
MAL  A1401 (-3.2A)
 1.01A 4n48A-4xaiA:
undetectable		 4n48A-4xaiA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 269
ALA A  53
GLY A  58
ASP A  16
 None
None
None
MAL  A1900 (-3.2A)
 0.95A 4n48A-4xajA:
undetectable		 4n48A-4xajA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A 901 (-2.9A)
 0.98A 4n48A-5azaA:
undetectable		 4n48A-5azaA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Escherichia
coli;
Acinetobacter
nosocomialis) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A1201 (-3.0A)
 0.97A 4n48A-5cfvA:
undetectable		 4n48A-5cfvA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 501 (-3.1A)
 0.99A 4n48A-5gpqA:
undetectable		 4n48A-5gpqA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		4 / 5 ASN A3934
ALA A3718
GLY A3723
ASP A3681
 None
None
None
MAL  A4201 (-2.6A)
 0.96A 4n48A-5ii5A:
undetectable		 4n48A-5ii5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		4 / 5 ASN A4236
ALA A4020
GLY A4025
ASP A3983
 None
None
None
MAL  A4501 (-3.0A)
 1.01A 4n48A-5iicA:
undetectable		 4n48A-5iicA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3
(Escherichia
coli;
Mus
musculus) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 501 (-2.5A)
 0.99A 4n48A-5osqA:
undetectable		 4n48A-5osqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A1501 (-3.2A)
 0.96A 4n48A-5tj2A:
undetectable		 4n48A-5tj2A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 501 (-2.9A)
 0.93A 4n48A-5wq6A:
undetectable		 4n48A-5wq6A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 6dm8 -
(-) 		4 / 5 ASN A  52
ALA A-164
GLY A-159
ASP A-201
 None
None
None
MAL  A 402 (-3.1A)
 0.98A 4n48A-6dm8A:
undetectable		 4n48A-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 4rwf MALTOSE TRANSPORTER
SUBUNIT, RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 2,
CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		4 / 6 GLU A 155
GLU A1105
ASN A 351
ARG A 356
 MAL  A2201 (-3.7A)
None
None
None
 1.32A 4ntxA-4rwfA:
2.4
4ntxC-4rwfA:
1.7		 4ntxA-4rwfA:
21.96
4ntxC-4rwfA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 1obb ALPHA-GLUCOSIDASE
(Thermotoga
maritima) 		3 / 3 PHE A 238
THR A  84
LEU A 300
 MAL  A 900 (-4.5A)
NAD  A 500 (-4.7A)
NAD  A 500 ( 4.9A)
 0.68A 4qztA-1obbA:
0.0		 4qztA-1obbA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1obb ALPHA-GLUCOSIDASE
(Thermotoga
maritima) 		5 / 12 THR A  84
ALA A 152
ALA A 151
ASN A 153
TYR A 296
 NAD  A 500 (-4.7A)
NAD  A 500 (-3.5A)
None
MAL  A 900 ( 3.1A)
MAL  A 900 (-4.2A)
 1.01A 4u15A-1obbA:
undetectable		 4u15A-1obbA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1obb ALPHA-GLUCOSIDASE
(Thermotoga
maritima) 		5 / 12 THR A  84
ALA A 152
ALA A 151
ASN A 153
TYR A 296
 NAD  A 500 (-4.7A)
NAD  A 500 (-3.5A)
None
MAL  A 900 ( 3.1A)
MAL  A 900 (-4.2A)
 1.13A 4u15B-1obbA:
undetectable		 4u15B-1obbA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 5edu MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HISTONE DEACETYLASE
6 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		4 / 7 SER B 479
TYR B 449
ARG B 174
SER B 445
 None
None
MAL  B2505 (-3.5A)
None
 1.20A 4xzkA-5eduB:
undetectable		 4xzkA-5eduB:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2
(Drosophila
melanogaster;
Escherichia
coli) 		4 / 6 GLU P 370
ASP P  64
ARG P  65
GLY P  68
 None
MAL  P 727 (-2.6A)
MAL  P 727 (-4.0A)
None
 0.86A 5cdnA-1r6zP:
undetectable
5cdnB-1r6zP:
undetectable		 5cdnA-1r6zP:
21.74
5cdnB-1r6zP:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 1obb ALPHA-GLUCOSIDASE
(Thermotoga
maritima) 		4 / 6 GLU A 404
GLY A 259
ASP A 260
GLY A 179
 None
None
MAL  A 900 (-2.8A)
None
 0.95A 5cdpA-1obbA:
0.0
5cdpB-1obbA:
undetectable		 5cdpA-1obbA:
21.85
5cdpB-1obbA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		3 / 3 GLU A  47
TRP A 342
ASN A  14
 None
MAL  A1401 (-3.7A)
MAL  A1401 (-4.6A)
 0.99A 5dv4A-4xaiA:
undetectable		 5dv4A-4xaiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		5 / 12 ILE A4317
ARG A4323
LEU A4422
LYS A4011
GLU A4122
 None
None
None
None
MAL  A4501 (-3.8A)
 1.37A 5il1A-5iicA:
undetectable		 5il1A-5iicA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		5 / 12 ILE A4317
ARG A4323
LEU A4422
LYS A4011
GLU A4122
 None
None
None
None
MAL  A4501 (-3.8A)
 1.35A 5k7uA-5iicA:
undetectable		 5k7uA-5iicA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Bacillus
cytotoxicus) 		3 / 3 THR A 117
HIS A 276
ASN A 113
 None
None
MAL  A 501 (-3.4A)
 0.69A 5n4tA-3k4hA:
undetectable		 5n4tA-3k4hA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Bacillus
cytotoxicus) 		5 / 12 LEU A  13
GLY A 251
ALA A 254
GLY A  99
ILE A  74
 None
None
None
MAL  A 501 (-3.3A)
None
 1.06A 5t2zA-3k4hA:
undetectable		 5t2zA-3k4hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 261
LYS A 298
ASP A 297
VAL A 294
ILE A  12
 MAL  A 501 ( 4.8A)
None
None
None
None
 1.01A 5wz1A-5z0rA:
undetectable		 5wz1A-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 261
LYS A 298
ASP A 297
VAL A 294
ILE A  12
 MAL  A 501 ( 4.8A)
None
None
None
None
 1.02A 5wz1C-5z0rA:
undetectable		 5wz1C-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 261
LYS A 298
ASP A 297
VAL A 294
ILE A  12
 MAL  A 501 ( 4.8A)
None
None
None
None
 1.05A 5wz1D-5z0rA:
undetectable		 5wz1D-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 261
LYS A 298
ASP A 297
VAL A 294
ILE A  12
 MAL  A 501 ( 4.8A)
None
None
None
None
 1.04A 5wz1E-5z0rA:
undetectable		 5wz1E-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 261
LYS A 298
ASP A 297
VAL A 294
ILE A  12
 MAL  A 501 ( 4.8A)
None
None
None
None
 1.05A 5wz1F-5z0rA:
undetectable		 5wz1F-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 261
LYS A 298
ASP A 297
VAL A 294
ILE A  12
 MAL  A 501 ( 4.8A)
None
None
None
None
 1.01A 5wz1G-5z0rA:
undetectable		 5wz1G-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 261
LYS A 298
ASP A 297
VAL A 294
ILE A  12
 MAL  A 501 ( 4.8A)
None
None
None
None
 1.03A 5wz1H-5z0rA:
undetectable		 5wz1H-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN
(Escherichia
coli;
Bovine
leukemia
virus) 		3 / 3 TYR A 181
ASN A 253
LEU A 139
 MAL  A1488 (-3.8A)
None
None
 0.83A 6b58A-2xz3A:
2.0		 6b58A-2xz3A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40
(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A 466 (-4.2A)
None
None
 0.68A 6b58A-3a3cA:
undetectable		 6b58A-3a3cA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3ehs FUSION PROTEIN OF
CRFR1 EXTRACELLULAR
DOMAIN AND MBP
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A-194
ASN A-122
LEU A-236
 MAL  A 126 (-4.1A)
None
None
 0.83A 6b58A-3ehsA:
undetectable		 6b58A-3ehsA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3mp6 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,LINKER,SAGA-
ASSOCIATED FACTOR 29
(Escherichia
coli;
Saccharomyces
cerevisiae;
unidentified) 		3 / 3 TYR A 893
ASN A 965
LEU A 851
 MAL  A 600 (-3.8A)
None
None
 0.80A 6b58A-3mp6A:
undetectable		 6b58A-3mp6A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		3 / 3 TYR A-215
ASN A-143
LEU A-257
 MAL  A 111 (-3.9A)
None
None
 0.82A 6b58A-3n93A:
undetectable		 6b58A-3n93A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3n94 FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PITUITARY
ADENYLATE CYCLASE 1
RECEPTOR-SHORT
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A-193
ASN A-121
LEU A-235
 MAL  A5044 (-3.8A)
None
None
 0.81A 6b58A-3n94A:
undetectable		 6b58A-3n94A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3oai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
MYELIN PROTEIN P0
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A1122 (-3.8A)
None
None
 0.83A 6b58A-3oaiA:
undetectable		 6b58A-3oaiA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A 700 (-3.9A)
None
None
 0.81A 6b58A-3osrA:
undetectable		 6b58A-3osrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 501 (-3.8A)
None
None
 0.82A 6b58A-4ifpA:
undetectable		 6b58A-4ifpA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4kv3 CHIMERA FUSION
PROTEIN OF ESX-1
SECRETION SYSTEM
PROTEIN ECCD1 AND
MALTOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli;
Mycobacterium
tuberculosis) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 501 (-3.9A)
None
None
 0.82A 6b58A-4kv3A:
undetectable		 6b58A-4kv3A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 157
ASN A 229
LEU A 115
 MAL  A1201 (-3.9A)
None
None
 0.80A 6b58A-4my2A:
undetectable		 6b58A-4my2A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		3 / 3 TYR A 157
ASN A 229
LEU A 115
 MAL  A1301 (-4.0A)
None
None
 0.83A 6b58A-4nufA:
2.8		 6b58A-4nufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4pe2 MALTOSE ABC
TRANSPORTER
PERIPLASMIC
PROTEIN,PREPILIN-TYP
E N-TERMINAL
CLEAVAGE/METHYLATION
DOMAIN PROTEIN
(Escherichia
coli;
Clostridioides
difficile) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A 601 (-3.9A)
None
None
 0.83A 6b58A-4pe2A:
undetectable		 6b58A-4pe2A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA
(Escherichia
coli;
Mycobacterium
tuberculosis) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 601 (-3.9A)
None
None
 0.82A 6b58A-4qvhA:
undetectable		 6b58A-4qvhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 179
ASN A 251
LEU A 137
 MAL  A 801 (-2.9A)
None
None
 0.82A 6b58A-4wrnA:
undetectable		 6b58A-4wrnA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4wvi MALTOSE-BINDING
PERIPLASMIC
PROTEIN,SIGNAL
PEPTIDASE IB
(Escherichia
coli;
Staphylococcus
aureus) 		3 / 3 TYR A 161
ASN A 233
LEU A 119
 MAL  A 601 (-3.9A)
None
None
 0.83A 6b58A-4wviA:
undetectable		 6b58A-4wviA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
(Escherichia
coli;
Tribolium
castaneum) 		3 / 3 TYR A 157
ASN A 229
LEU A 115
 MAL  A1401 (-3.8A)
None
None
 0.82A 6b58A-4xaiA:
undetectable		 6b58A-4xaiA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4xaj MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NUCLEAR
RECEPTOR SUBFAMILY 2
GROUP E MEMBER 1
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 157
ASN A 229
LEU A 115
 MAL  A1900 (-4.2A)
None
None
 0.80A 6b58A-4xajA:
2.6		 6b58A-4xajA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN
(Escherichia
coli;
Pyrococcus
furiosus) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A 901 (-3.8A)
None
None
 0.82A 6b58A-5azaA:
undetectable		 6b58A-5azaA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN
(Escherichia
coli;
Acinetobacter
nosocomialis) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A1201 (-3.9A)
None
None
 0.81A 6b58A-5cfvA:
undetectable		 6b58A-5cfvA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19
(Escherichia
coli;
Tetrahymena
thermophila) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A 601 (-4.0A)
None
None
 0.81A 6b58A-5dfmA:
undetectable		 6b58A-5dfmA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5edu MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HISTONE DEACETYLASE
6 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR B 263
ASN B 335
LEU B 221
 MAL  B2505 (-4.1A)
None
None
 0.82A 6b58A-5eduB:
2.3		 6b58A-5eduB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 501 (-3.9A)
None
None
 0.84A 6b58A-5gpqA:
undetectable		 6b58A-5gpqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		3 / 3 TYR A3822
ASN A3894
LEU A3780
 MAL  A4201 (-2.8A)
None
None
 0.81A 6b58A-5ii5A:
undetectable		 6b58A-5ii5A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR
(Escherichia
coli;
Haliotis
rufescens) 		3 / 3 TYR A4124
ASN A4196
LEU A4082
 MAL  A4501 (-3.0A)
None
None
 0.82A 6b58A-5iicA:
undetectable		 6b58A-5iicA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2
(Escherichia
coli;
Mus
musculus) 		3 / 3 TYR A-214
ASN A-142
LEU A-256
 MAL  A 701 (-3.9A)
None
None
 0.83A 6b58A-5jonA:
undetectable		 6b58A-5jonA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5osq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ZONA
PELLUCIDA
SPERM-BINDING
PROTEIN 3
(Escherichia
coli;
Mus
musculus) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 501 (-2.7A)
None
None
 0.81A 6b58A-5osqA:
undetectable		 6b58A-5osqA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A1501 (-3.9A)
None
None
 0.82A 6b58A-5tj2A:
3.3		 6b58A-5tj2A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5v6y MALTOSE-BINDING
PERIPLASMIC
PROTEIN,RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1,CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 157
ASN A 229
LEU A 115
 MAL  A2201 (-3.9A)
None
None
 0.83A 6b58A-5v6yA:
undetectable		 6b58A-5v6yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5wq6 MBP TAGGED HMNDA-PYD
(Homo
sapiens) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 501 (-3.8A)
None
None
 0.82A 6b58A-5wq6A:
undetectable		 6b58A-5wq6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5z0r EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY
1,VIRAL GENOME
PROTEIN
(Escherichia
coli) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 501 (-2.9A)
None
None
 0.78A 6b58A-5z0rA:
undetectable		 6b58A-5z0rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 6dm8 -
(-) 		3 / 3 TYR A -60
ASN A  12
LEU A-102
 MAL  A 402 (-4.1A)
None
None
 0.66A 6b58A-6dm8A:
2.3		 6b58A-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)
(Bacillus
cereus) 		5 / 11 THR A 229
GLU A 231
ALA A 317
LEU A 435
ALA A 365
 None
MAL  A 501 (-3.6A)
None
None
None
 1.18A 6efnA-6bvgA:
undetectable		 6efnA-6bvgA:
undetectable