SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MAF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		3 / 3 HIS A 143
TRP A 156
SER A 141
 MAF  A1427 ( 3.9A)
None
None
 1.13A 4lrhD-1gw1A:
undetectable		 4lrhD-1gw1A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE
(Cellvibrio
japonicus) 		4 / 6 GLU A 320
ARG A 208
ALA A 212
TYR A 285
 MAF  A1427 (-2.2A)
ZN  A1424 (-2.2A)
None
MBF  A1428 ( 3.9A)
 1.08A 5phhA-1gw1A:
undetectable		 5phhA-1gw1A:
19.75