SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'M7P'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2xbl PHOSPHOHEPTOSE
ISOMERASE
(Burkholderia
pseudomallei) 		4 / 5 ASN A 130
THR A 171
SER A 123
ARG A 152
 None
M7P  A1198 (-3.7A)
M7P  A1198 (-2.6A)
None
 1.34A 3hlwB-2xblA:
undetectable		 3hlwB-2xblA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUO_D_PFLD402_1
(PROTON-GATED ION
CHANNEL)		 2xbl PHOSPHOHEPTOSE
ISOMERASE
(Burkholderia
pseudomallei) 		5 / 9 SER A  58
SER A 128
ILE A 131
SER A 125
THR A 171
 M7P  A1198 ( 4.2A)
M7P  A1198 (-2.5A)
None
M7P  A1198 (-2.6A)
M7P  A1198 (-3.7A)
 1.26A 5muoA-2xblA:
undetectable
5muoB-2xblA:
undetectable
5muoC-2xblA:
undetectable
5muoD-2xblA:
undetectable
5muoE-2xblA:
1.0		 5muoA-2xblA:
25.78
5muoB-2xblA:
25.78
5muoC-2xblA:
25.78
5muoD-2xblA:
25.78
5muoE-2xblA:
25.78