SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'M7G'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA8_0
(MINI-GRAMICIDIN A)		 1ap8 TRANSLATION
INITIATION FACTOR
EIF4E
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 153
TRP A  58
ALA A 164
TRP A 104
 None
M7G  A 214 (-2.9A)
None
M7G  A 214 (-3.1A)
 1.39A 1kqeA-1ap8A:
undetectable
1kqeE-1ap8A:
undetectable		 1kqeA-1ap8A:
8.55
1kqeE-1ap8A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5bv3 M7GPPPX
DIPHOSPHATASE
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 233
PRO A 262
ILE A 294
LEU A 291
 None
M7G  A 401 (-4.6A)
None
None
 1.12A 1ya4B-5bv3A:
undetectable		 1ya4B-5bv3A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5bv3 M7GPPPX
DIPHOSPHATASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 158
HIS A 123
TYR A 264
 None
None
M7G  A 401 (-4.7A)
 1.14A 4fu8A-5bv3A:
undetectable		 4fu8A-5bv3A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5bv3 M7GPPPX
DIPHOSPHATASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 158
HIS A 123
TYR A 264
 None
None
M7G  A 401 (-4.7A)
 1.14A 4fu9A-5bv3A:
undetectable		 4fu9A-5bv3A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1ap8 TRANSLATION
INITIATION FACTOR
EIF4E
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 118
SER A 116
ASP A  92
ASP A  53
 None
None
M7G  A 214 (-3.6A)
M7G  A 214 ( 4.9A)
 1.33A 4qtuB-1ap8A:
undetectable		 4qtuB-1ap8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1ap8 TRANSLATION
INITIATION FACTOR
EIF4E
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 118
SER A 116
ASP A  92
ASP A  53
 None
None
M7G  A 214 (-3.6A)
M7G  A 214 ( 4.9A)
 1.29A 4qtuD-1ap8A:
undetectable		 4qtuD-1ap8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1ap8 TRANSLATION
INITIATION FACTOR
EIF4E
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  92
HIS A  94
GLU A  83
ASP A 127
 M7G  A 214 (-3.6A)
M7G  A 214 ( 4.1A)
None
None
 1.10A 6mn4D-1ap8A:
undetectable		 6mn4D-1ap8A:
23.62