SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'M7B'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.81A 2pkkA-4e84A:
24.8		 2pkkA-4e84A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.81A 2pkmA-4e84A:
24.6		 2pkmA-4e84A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		6 / 12 ASP A  29
GLY A  58
GLY A  59
ASN A  62
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
None
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 1.07A 3uboA-4e84A:
26.4		 3uboA-4e84A:
27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.78A 4dc3B-4e84A:
25.8		 4dc3B-4e84A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.68A 4e3aB-4e84A:
27.1		 4e3aB-4e84A:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
ASN A  62
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
None
M7B  A 502 (-3.1A)
 1.05A 4k8tB-4e84A:
27.3		 4k8tB-4e84A:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
ASN A  62
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
None
M7B  A 502 (-3.1A)
 1.07A 4k9iA-4e84A:
27.3		 4k9iA-4e84A:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
ASN A  62
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
None
M7B  A 502 (-3.1A)
 1.07A 4k9iB-4e84A:
27.3		 4k9iB-4e84A:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_C_FOLC301_0
(FOLATE RECEPTOR
ALPHA)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A 270
GLN A 122
ARG A 115
ARG A 125
TYR A 159
 M7B  A 502 (-3.1A)
None
M7B  A 502 (-3.2A)
M7B  A 502 (-3.1A)
M7B  A 502 (-4.5A)
 1.22A 4lrhC-4e84A:
0.0		 4lrhC-4e84A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_E_FOLE301_0
(FOLATE RECEPTOR
ALPHA)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A 270
GLN A 122
ARG A 115
ARG A 125
TYR A 159
 M7B  A 502 (-3.1A)
None
M7B  A 502 (-3.2A)
M7B  A 502 (-3.1A)
M7B  A 502 (-4.5A)
 1.15A 4lrhE-4e84A:
0.0		 4lrhE-4e84A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A 270
ASN A  62
ALA A  61
ASP A 184
 M7B  A 502 (-3.1A)
None
None
MG  A 506 ( 3.6A)
 1.19A 4mdbA-4e84A:
undetectable		 4mdbA-4e84A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  59
ASN A  62
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.6A)
None
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 1.16A 4n09A-4e84A:
27.1		 4n09A-4e84A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.94A 4n09B-4e84A:
26.9		 4n09B-4e84A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.93A 4n09C-4e84A:
26.9		 4n09C-4e84A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.94A 4n09D-4e84A:
26.6		 4n09D-4e84A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  29
GLY A  58
GLY A  59
GLY A 267
ASP A 270
 M7B  A 502 (-2.9A)
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
M7B  A 502 (-3.7A)
M7B  A 502 (-3.1A)
 0.68A 5kb5A-4e84A:
26.5		 5kb5A-4e84A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 11 ALA A  64
ALA A 274
GLY A  58
GLY A  59
ALA A  60
 None
None
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
None
 1.00A 5lf3K-4e84A:
undetectable
5lf3L-4e84A:
undetectable		 5lf3K-4e84A:
22.13
5lf3L-4e84A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE
(Burkholderia
cenocepacia) 		5 / 11 ALA A  64
ALA A 274
GLY A  58
GLY A  59
ALA A  60
 None
None
M7B  A 502 (-3.4A)
M7B  A 502 (-3.6A)
None
 1.00A 5lf3Y-4e84A:
undetectable
5lf3Z-4e84A:
undetectable		 5lf3Y-4e84A:
22.13
5lf3Z-4e84A:
20.79