SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'M44'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3l7g XAA-PRO DIPEPTIDASE
(Alteromonas
sp.) 		5 / 10 ILE A 256
ALA A 247
HIS A 179
TYR A 199
TYR A 212
 None
None
None
None
M44  A 518 (-3.6A)
 1.47A 3boyA-3l7gA:
1.9
3boyC-3l7gA:
undetectable		 3boyA-3l7gA:
17.48
3boyC-3l7gA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3l7g XAA-PRO DIPEPTIDASE
(Alteromonas
sp.) 		5 / 10 TYR A 199
TYR A 212
ILE A 256
ALA A 247
HIS A 179
 None
M44  A 518 (-3.6A)
None
None
None
 1.47A 3boyA-3l7gA:
1.9
3boyB-3l7gA:
undetectable		 3boyA-3l7gA:
17.48
3boyB-3l7gA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA3001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3l7g XAA-PRO DIPEPTIDASE
(Alteromonas
sp.) 		5 / 10 TYR A 199
TYR A 212
ILE A 256
ALA A 247
HIS A 179
 None
M44  A 518 (-3.6A)
None
None
None
 1.45A 3boyB-3l7gA:
undetectable
3boyC-3l7gA:
undetectable		 3boyB-3l7gA:
17.48
3boyC-3l7gA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_A_VIBA191_1
(THIT)		 3l7g XAA-PRO DIPEPTIDASE
(Alteromonas
sp.) 		5 / 10 GLU A 381
TYR A 212
HIS A 336
GLY A 339
VAL A 377
 MN  A 519 ( 2.7A)
M44  A 518 (-3.6A)
MN  A 519 (-3.3A)
None
None
 1.30A 3rlbA-3l7gA:
0.0		 3rlbA-3l7gA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 3l7g XAA-PRO DIPEPTIDASE
(Alteromonas
sp.) 		5 / 12 GLU A 381
TYR A 212
HIS A 336
GLY A 339
VAL A 377
 MN  A 519 ( 2.7A)
M44  A 518 (-3.6A)
MN  A 519 (-3.3A)
None
None
 1.30A 3rlbB-3l7gA:
undetectable		 3rlbB-3l7gA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 3l7g XAA-PRO DIPEPTIDASE
(Alteromonas
sp.) 		4 / 5 ILE A 423
HIS A 332
TYR A 212
VAL A 342
 None
M44  A 518 (-3.7A)
M44  A 518 (-3.6A)
None
 1.36A 4s0vA-3l7gA:
undetectable		 4s0vA-3l7gA:
21.01