SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'M43'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3sqg METHYL COENZYME M
REDUCTASE, ALPHA
SUBUNIT
(uncultured
archaeon) 		3 / 3 ASN A 145
HIS A 146
VAL A 153
 None
None
M43  A1001 (-3.5A)
 0.84A 3elzB-3sqgA:
undetectable		 3elzB-3sqgA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3sqg METHYL COENZYME M
REDUCTASE, ALPHA
SUBUNIT
(uncultured
archaeon) 		5 / 12 ALA A 257
VAL A 153
GLY A 151
ALA A 147
LEU A 148
 M43  A1001 (-3.4A)
M43  A1001 (-3.5A)
None
None
None
 1.06A 5jw1A-3sqgA:
undetectable		 5jw1A-3sqgA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3sqg METHYL COENZYME M
REDUCTASE, ALPHA
SUBUNIT
(uncultured
archaeon) 		5 / 12 ALA A 257
VAL A 153
GLY A 151
ALA A 147
LEU A 148
 M43  A1001 (-3.4A)
M43  A1001 (-3.5A)
None
None
None
 1.02A 5jw1B-3sqgA:
undetectable		 5jw1B-3sqgA:
22.76