SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'M0E'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3hzs MONOFUNCTIONAL
GLYCOSYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ASN A 224
VAL A 223
ILE A 231
LEU A 214
ALA A 192
 M0E  A 901 (-3.9A)
M0E  A 901 (-4.8A)
None
None
None
 1.27A 2iyfB-3hzsA:
undetectable		 2iyfB-3hzsA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 3hzs MONOFUNCTIONAL
GLYCOSYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 VAL A 223
ASN A 245
MET A 249
ALA A  95
PHE A  96
 M0E  A 901 (-4.8A)
None
None
None
None
 1.45A 3nuvA-3hzsA:
undetectable		 3nuvA-3hzsA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3hzs MONOFUNCTIONAL
GLYCOSYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 ASN A 224
VAL A 223
ILE A 231
LEU A 214
ALA A 192
 M0E  A 901 (-3.9A)
M0E  A 901 (-4.8A)
None
None
None
 1.29A 4m83A-3hzsA:
undetectable		 4m83A-3hzsA:
18.80