SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'LZ6'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSE_A_EAAA224_1 (GLUTATHIONETRANSFERASE) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 12 | PHE A 10ARG A 13PRO A 110VAL A 111ALA A 216 | NoneNoneLZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.97A | 1gseA-4hj2A:35.9 | 1gseA-4hj2A:99.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSE_A_EAAA224_1 (GLUTATHIONETRANSFERASE) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 8 / 12 | TYR A 9ARG A 13GLY A 14LEU A 107LEU A 108PRO A 110VAL A 111ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 ( 3.9A)LZ6 A 301 (-4.4A)NoneLZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.57A | 1gseA-4hj2A:35.9 | 1gseA-4hj2A:99.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSE_A_EAAA224_1 (GLUTATHIONETRANSFERASE) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 12 | TYR A 9ARG A 13GLY A 14MET A 208ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 ( 3.9A)LZ6 A 301 (-4.0A)LZ6 A 301 ( 4.6A) | 0.83A | 1gseA-4hj2A:35.9 | 1gseA-4hj2A:99.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSE_B_EAAB224_1 (GLUTATHIONETRANSFERASE) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 9 / 12 | TYR A 9ARG A 13GLY A 14LEU A 107LEU A 108PRO A 110VAL A 111LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 ( 3.9A)LZ6 A 301 (-4.4A)NoneLZ6 A 301 (-3.5A)NoneNoneLZ6 A 301 ( 4.6A) | 0.56A | 1gseB-4hj2A:36.0 | 1gseB-4hj2A:99.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSE_B_EAAB224_1 (GLUTATHIONETRANSFERASE) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 12 | TYR A 9ARG A 13GLY A 14MET A 208LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 ( 3.9A)LZ6 A 301 (-4.0A)NoneLZ6 A 301 ( 4.6A) | 1.00A | 1gseB-4hj2A:36.0 | 1gseB-4hj2A:99.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSF_A_EAAA223_1 (GLUTATHIONETRANSFERASE A1-1) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107MET A 208PHE A 220 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-4.0A)LZ6 A 301 (-3.7A) | 0.44A | 1gsfA-4hj2A:36.3 | 1gsfA-4hj2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSF_A_EAAA223_1 (GLUTATHIONETRANSFERASE A1-1) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107VAL A 111MET A 208 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)NoneLZ6 A 301 (-4.0A) | 0.55A | 1gsfA-4hj2A:36.3 | 1gsfA-4hj2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSF_B_EAAB223_1 (GLUTATHIONETRANSFERASE A1-1) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107MET A 208PHE A 220 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-4.0A)LZ6 A 301 (-3.7A) | 0.44A | 1gsfB-4hj2A:36.3 | 1gsfB-4hj2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSF_B_EAAB223_1 (GLUTATHIONETRANSFERASE A1-1) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107VAL A 111MET A 208 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)NoneLZ6 A 301 (-4.0A) | 0.55A | 1gsfB-4hj2A:36.3 | 1gsfB-4hj2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSF_C_EAAC223_1 (GLUTATHIONETRANSFERASE A1-1) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 7 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107VAL A 111MET A 208PHE A 220 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)NoneLZ6 A 301 (-4.0A)LZ6 A 301 (-3.7A) | 0.65A | 1gsfC-4hj2A:36.3 | 1gsfC-4hj2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSF_D_EAAD223_1 (GLUTATHIONETRANSFERASE A1-1) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107MET A 208PHE A 220 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-4.0A)LZ6 A 301 (-3.7A) | 0.45A | 1gsfD-4hj2A:36.3 | 1gsfD-4hj2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1GSF_D_EAAD223_1 (GLUTATHIONETRANSFERASE A1-1) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107VAL A 111MET A 208 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)NoneLZ6 A 301 (-4.0A) | 0.55A | 1gsfD-4hj2A:36.3 | 1gsfD-4hj2A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1Q23_A_FUAA702_1 (CHLORAMPHENICOLACETYLTRANSFERASE) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 12 | THR A 68TYR A 9LEU A 108VAL A 111ALA A 12 | LZ6 A 301 (-3.5A)LZ6 A 301 (-4.6A)NoneNoneNone | 1.19A | 1q23A-4hj2A:undetectable1q23B-4hj2A:undetectable | 1q23A-4hj2A:17.961q23B-4hj2A:17.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCT_A_ASDA1223_1 (GLUTATHIONES-TRANSFERASE A2) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107LEU A 108 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)None | 0.43A | 2vctA-4hj2A:36.0 | 2vctA-4hj2A:94.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCT_B_ASDB1223_1 (GLUTATHIONES-TRANSFERASE A2) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107LEU A 108 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)None | 0.44A | 2vctB-4hj2A:35.8 | 2vctB-4hj2A:94.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCT_C_ASDC1223_1 (GLUTATHIONES-TRANSFERASE A2) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 8 | TYR A 9GLY A 14ARG A 15LEU A 107LEU A 108 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)None | 0.40A | 2vctC-4hj2A:36.0 | 2vctC-4hj2A:94.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCT_D_ASDD1223_1 (GLUTATHIONES-TRANSFERASE A2) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 4 / 7 | TYR A 9GLY A 14ARG A 15LEU A 108 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneNone | 0.42A | 2vctD-4hj2A:35.7 | 2vctD-4hj2A:94.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_A_ASDA1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 4 / 7 | TYR A 9PHE A 10PRO A 110ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 (-3.5A)LZ6 A 301 ( 4.6A) | 0.67A | 2vcvA-4hj2A:36.4 | 2vcvA-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_A_ASDA1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 4 / 7 | TYR A 9PRO A 110LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.70A | 2vcvA-4hj2A:36.4 | 2vcvA-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_B_ASDB1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 6 | PHE A 10LEU A 107PRO A 110LEU A 213ALA A 216 | NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.80A | 2vcvB-4hj2A:36.4 | 2vcvB-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_D_ASDD1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 9 | TYR A 9PHE A 10LEU A 107PRO A 110LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.79A | 2vcvD-4hj2A:36.5 | 2vcvD-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_E_ASDE1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 9 | TYR A 9PHE A 10LEU A 107PRO A 110LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.84A | 2vcvE-4hj2A:36.4 | 2vcvE-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_G_ASDG1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 4 / 7 | LEU A 108PRO A 110LEU A 213ALA A 216 | NoneLZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.84A | 2vcvG-4hj2A:36.5 | 2vcvG-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_G_ASDG1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 5 / 7 | PHE A 10LEU A 107PRO A 110LEU A 213ALA A 216 | NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.74A | 2vcvG-4hj2A:36.5 | 2vcvG-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_H_ASDH1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 9 | TYR A 9PHE A 10LEU A 107PRO A 110LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.83A | 2vcvH-4hj2A:36.4 | 2vcvH-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_I_ASDI1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 9 | TYR A 9PHE A 10LEU A 107PRO A 110LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.67A | 2vcvI-4hj2A:36.5 | 2vcvI-4hj2A:90.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VCV_P_ASDP1224_1 (GLUTATHIONES-TRANSFERASE A3) |
4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homosapiens) | 6 / 8 | PHE A 10LEU A 107LEU A 108PRO A 110LEU A 213ALA A 216 | NoneLZ6 A 301 (-4.4A)NoneLZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.68A | 2vcvP-4hj2A:36.3 | 2vcvP-4hj2A:90.78 |