SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'LXV'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1STF_E_CCSE25_0 (PAPAIN STEFIN B (CYSTATIN B))	3pdf	DIPEPTIDYL PEPTIDASE 1 (Homo sapiens)	6 / 10	GLN A 228 GLY A 232 SER A 233 PHE A 237 HIS A 381 ALA A 382	LXV A 442 (-3.4A) LXV A 442 (-3.5A) None None None LXV A 442 ( 3.8A)	0.31A	1stfE-3pdfA: 29.4 1stfI-3pdfA: undetectable	1stfE-3pdfA: 19.00 1stfI-3pdfA: 11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AI8_A_HNQA255_1 (CATHEPSIN B)	3pdf	DIPEPTIDYL PEPTIDASE 1 (Homo sapiens)	4 / 7	GLN A 228 GLY A 232 HIS A 381 TRP A 405	LXV A 442 (-3.4A) LXV A 442 (-3.5A) None None	0.51A	3ai8A-3pdfA: 29.6	3ai8A-3pdfA: 24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IH0_A_ACTA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	3pdf	DIPEPTIDYL PEPTIDASE 1 (Homo sapiens)	4 / 6	PHE A 278 PRO A 279 THR A 379 ILE A 429	LXV A 442 ( 3.8A) CL A 443 ( 4.0A) LXV A 442 (-4.2A) None	1.27A	5ih0A-3pdfA: 1.7	5ih0A-3pdfA: 20.77