SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'LVG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		7 / 7 ARG A  90
ASN A 208
HIS A 223
PHE A 227
TYR A 372
ILE A 430
TRP A 465
 LVG  A 491 (-3.5A)
LVG  A 487 (-3.9A)
LVG  A 487 (-2.5A)
LVG  A 487 (-3.9A)
LVG  A 491 ( 4.9A)
FAD  A 488 (-4.7A)
None
 0.23A 1tdnA-1tdkA:
64.2		 1tdnA-1tdkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 ARG A  90
HIS A 223
PHE A 227
ILE A 374
 LVG  A 491 (-3.5A)
LVG  A 487 (-2.5A)
LVG  A 487 (-3.9A)
LVG  A 491 ( 4.6A)
 0.91A 1tdnA-1tdkA:
64.2		 1tdnA-1tdkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 ASN A 208
HIS A 223
PHE A 227
TYR A 356
 LVG  A 487 (-3.9A)
LVG  A 487 (-2.5A)
LVG  A 487 (-3.9A)
None
 1.41A 1tdnA-1tdkA:
64.2		 1tdnA-1tdkA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 MET A 207
TYR A 157
HIS A 223
GLY A 204
ILE A 203
 None
None
LVG  A 487 (-2.5A)
None
None
 1.48A 2zm7A-1tdkA:
0.0		 2zm7A-1tdkA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 MET A 207
TYR A 157
HIS A 223
GLY A 204
ILE A 203
 None
None
LVG  A 487 (-2.5A)
None
None
 1.49A 2zm8A-1tdkA:
0.0		 2zm8A-1tdkA:
22.16