SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'LSD'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YJA_B_ESTB1550_1 (ESTROGEN RECEPTOR)	4rzm	EPOXIDE HYDROLASE LASB (Streptomyces lasaliensis)	5 / 12	LEU A 233 MET A 219 ILE A 247 GLY A 225 LEU A 227	None LSD A 301 ( 4.1A) None None LSD A 301 ( 4.6A)	1.19A	2yjaB-4rzmA: undetectable	2yjaB-4rzmA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA151_0 (ILEAL BILE ACID-BINDING PROTEIN)	4rzm	EPOXIDE HYDROLASE LASB (Streptomyces lasaliensis)	4 / 7	TYR A 162 TYR A 251 VAL A 215 LEU A 158	None LSD A 301 ( 3.8A) None None	0.87A	3elzA-4rzmA: 1.3	3elzA-4rzmA: 16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WGQ_A_ESTA601_1 (ESTROGEN RECEPTOR)	4rzm	EPOXIDE HYDROLASE LASB (Streptomyces lasaliensis)	5 / 9	LEU A 233 MET A 234 MET A 219 GLY A 225 LEU A 227	None None LSD A 301 ( 4.1A) None LSD A 301 ( 4.6A)	1.31A	5wgqA-4rzmA: undetectable	5wgqA-4rzmA: 12.32