SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'LPP'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ERR_B_RALB600_1 (ESTROGEN RECEPTOR) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 6 / 12 | TRP A 318LEU A 322ILE A 385LEU A 476LEU A 487LEU A 490 | NoneLPP A 1 ( 4.8A)NoneLPP A 1 (-4.2A)NoneNone | 0.89A | 1errB-1hg4A:24.1 | 1errB-1hg4A:27.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1FM6_A_9CRA501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.76A | 1fm6A-1hg4A:24.0 | 1fm6A-1hg4A:44.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1FM6_U_9CRU502_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | LEU A 366VAL A 382CYH A 472HIS A 475LEU A 476 | LPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)NoneLPP A 1 (-4.2A) | 0.66A | 1fm6U-1hg4A:24.3 | 1fm6U-1hg4A:44.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1FM6_U_9CRU502_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 6 / 12 | TRP A 318VAL A 382ILE A 385CYH A 472HIS A 475LEU A 476 | NoneLPP A 1 (-4.8A)NoneLPP A 1 ( 4.2A)NoneLPP A 1 (-4.2A) | 1.14A | 1fm6U-1hg4A:24.3 | 1fm6U-1hg4A:44.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1FM9_A_9CRA201_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.62A | 1fm9A-1hg4A:24.1 | 1fm9A-1hg4A:44.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1FM9_A_9CRA201_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.75A | 1fm9A-1hg4A:24.1 | 1fm9A-1hg4A:44.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1K74_A_9CRA463_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.67A | 1k74A-1hg4A:24.2 | 1k74A-1hg4A:44.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1K74_A_9CRA463_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.80A | 1k74A-1hg4A:24.2 | 1k74A-1hg4A:44.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XDK_A_9CRA500_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.71A | 1xdkA-1hg4A:24.7 | 1xdkA-1hg4A:43.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XDK_E_9CRE1500_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.71A | 1xdkE-1hg4A:24.7 | 1xdkE-1hg4A:43.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XIU_B_9CRB202_1 (RXR-LIKE PROTEIN) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | LEU A 322VAL A 382CYH A 472HIS A 475LEU A 476 | LPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)NoneLPP A 1 (-4.2A) | 0.46A | 1xiuB-1hg4A:24.2 | 1xiuB-1hg4A:41.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_A_9CRA801_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.50A | 1xlsA-1hg4A:24.0 | 1xlsA-1hg4A:45.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_A_9CRA801_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.65A | 1xlsA-1hg4A:24.0 | 1xlsA-1hg4A:45.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_B_9CRB802_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.51A | 1xlsB-1hg4A:24.0 | 1xlsB-1hg4A:45.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_B_9CRB802_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.65A | 1xlsB-1hg4A:24.0 | 1xlsB-1hg4A:45.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_C_9CRC803_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.50A | 1xlsC-1hg4A:24.0 | 1xlsC-1hg4A:45.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_C_9CRC803_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.65A | 1xlsC-1hg4A:24.0 | 1xlsC-1hg4A:45.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_D_9CRD804_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.49A | 1xlsD-1hg4A:24.0 | 1xlsD-1hg4A:45.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XLS_D_9CRD804_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.65A | 1xlsD-1hg4A:24.0 | 1xlsD-1hg4A:45.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3DZU_A_9CRA7223_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | ILE A 323LEU A 366VAL A 382HIS A 475LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)NoneLPP A 1 (-4.2A) | 0.79A | 3dzuA-1hg4A:24.4 | 3dzuA-1hg4A:26.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3DZU_A_9CRA7223_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | ILE A 323VAL A 382CYH A 472HIS A 475LEU A 476 | NoneLPP A 1 (-4.8A)LPP A 1 ( 4.2A)NoneLPP A 1 (-4.2A) | 0.51A | 3dzuA-1hg4A:24.4 | 3dzuA-1hg4A:26.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3H0A_A_9RAA500_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382ILE A 385LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)NoneLPP A 1 (-4.2A) | 0.74A | 3h0aA-1hg4A:23.1 | 3h0aA-1hg4A:42.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3H0A_A_9RAA500_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382ILE A 385LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)NoneLPP A 1 (-4.2A) | 0.78A | 3h0aA-1hg4A:23.1 | 3h0aA-1hg4A:42.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4DC3_B_2FAB401_2 (ADENOSINE KINASE) |
5z96 | SHORT TRANSIENTRECEPTOR POTENTIALCHANNEL 4 (Musmusculus) | 4 / 5 | LEU A 527ILE A 607ALA A 529PHE A 530 | LPP A 802 (-4.7A)NoneNoneNone | 0.87A | 4dc3B-5z96A:undetectable | 4dc3B-5z96A:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4EAH_A_ACTA1002_0 (ACTIN, ALPHASKELETAL MUSCLEFORMIN-LIKE PROTEIN3) |
5z96 | SHORT TRANSIENTRECEPTOR POTENTIALCHANNEL 4 (Musmusculus) | 4 / 5 | THR A 563GLN A 569GLU A 566THR A 567 | NoneLPP A 802 (-3.2A)NoneNone | 1.34A | 4eahA-5z96A:0.94eahE-5z96A:0.94eahG-5z96A:undetectable | 4eahA-5z96A:undetectable4eahE-5z96A:undetectable4eahG-5z96A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4G1B_D_ECND403_1 (FLAVOHEMOGLOBIN) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | ILE A 481THR A 482PHE A 491LEU A 476ILE A 323 | NoneNoneNoneLPP A 1 (-4.2A)None | 0.99A | 4g1bD-1hg4A:undetectable | 4g1bD-1hg4A:20.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5JI0_A_9CRA501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 11 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.51A | 5ji0A-1hg4A:24.3 | 5ji0A-1hg4A:44.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5JI0_A_9CRA501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 11 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.74A | 5ji0A-1hg4A:24.3 | 5ji0A-1hg4A:44.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5UAN_A_9CRA503_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.81A | 5uanA-1hg4A:24.3 | 5uanA-1hg4A:32.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5UC3_A_486A801_2 (GLUCOCORTICOIDRECEPTOR) |
5z96 | SHORT TRANSIENTRECEPTOR POTENTIALCHANNEL 4 (Musmusculus) | 4 / 5 | LEU A 513LEU A 517MET A 437GLN A 506 | LPP A 802 (-4.3A)NoneNoneNone | 1.38A | 5uc3A-5z96A:undetectable | 5uc3A-5z96A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Z12_B_9CRB501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 322VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.8A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.59A | 5z12B-1hg4A:24.7 | 5z12B-1hg4A:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Z12_B_9CRB501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.67A | 5z12B-1hg4A:24.7 | 5z12B-1hg4A:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Z12_C_9CRC501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366VAL A 382CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)LPP A 1 (-4.8A)LPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.71A | 5z12C-1hg4A:24.3 | 5z12C-1hg4A:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6A5Y_D_9CRD501_0 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | TRP A 318LEU A 366ILE A 385CYH A 472LEU A 476 | NoneLPP A 1 ( 4.4A)NoneLPP A 1 ( 4.2A)LPP A 1 (-4.2A) | 0.74A | 6a5yD-1hg4A:25.0 | 6a5yD-1hg4A:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6A5Z_L_9CRL501_0 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | LEU A 366ILE A 385CYH A 472HIS A 475LEU A 476 | LPP A 1 ( 4.4A)NoneLPP A 1 ( 4.2A)NoneLPP A 1 (-4.2A) | 0.74A | 6a5zL-1hg4A:24.9 | 6a5zL-1hg4A:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6A60_D_9CRD501_0 (RETINOIC ACIDRECEPTOR RXR-ALPHA) |
1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) | 5 / 12 | LEU A 322ILE A 385CYH A 472HIS A 475LEU A 476 | LPP A 1 ( 4.8A)NoneLPP A 1 ( 4.2A)NoneLPP A 1 (-4.2A) | 0.55A | 6a60D-1hg4A:24.7 | 6a60D-1hg4A:17.94 |