SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'LNL'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_G_EY4G501_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	2byo	LIPOPROTEIN LPPX (Mycobacterium tuberculosis)	4 / 7	ILE A 92 VAL A 94 ILE A 57 THR A 76	None None LNL A1216 ( 4.2A) None	0.98A	6cduF-2byoA: undetectable 6cduG-2byoA: undetectable	6cduF-2byoA: 23.31 6cduG-2byoA: 23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_G_EY4G502_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	2byo	LIPOPROTEIN LPPX (Mycobacterium tuberculosis)	4 / 8	ILE A 92 VAL A 94 ILE A 57 THR A 76	None None LNL A1216 ( 4.2A) None	1.04A	6cduG-2byoA: undetectable 6cduH-2byoA: undetectable	6cduG-2byoA: 23.31 6cduH-2byoA: 23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_E_PCFE202_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 1)	2byo	LIPOPROTEIN LPPX (Mycobacterium tuberculosis)	4 / 8	ALA A 184 VAL A 171 ARG A 183 ASP A 140	LNL A1217 ( 4.1A) HXA A1215 ( 4.4A) None None	0.99A	6hu9a-2byoA: undetectable 6hu9e-2byoA: undetectable	6hu9a-2byoA: 19.35 6hu9e-2byoA: 23.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["6CDU_G_EY4G501_0","CHIMERIC ALPHA1GABAA RECEPTOR","2byo","LIPOPROTEIN LPPX","Mycobacterium tuberculosis",4,"ILE A  92;VAL A  94;ILE A  57;THR A  76","None;None;LNL A1216 ( 4.2A);None","0.98A","6cduF-2byoA:undetectable;6cduG-2byoA:undetectable",null],["6CDU_G_EY4G502_0","CHIMERIC ALPHA1GABAA RECEPTOR","2byo","LIPOPROTEIN LPPX","Mycobacterium tuberculosis",4,"ILE A  92;VAL A  94;ILE A  57;THR A  76","None;None;LNL A1216 ( 4.2A);None","1.04A","6cduG-2byoA:undetectable;6cduH-2byoA:undetectable","6cduF-2byoA:23.31;6cduG-2byoA:23.31"],["6HU9_E_PCFE202_0","CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL;CYTOCHROME C OXIDASE SUBUNIT 1","2byo","LIPOPROTEIN LPPX","Mycobacterium tuberculosis",4,"ALA A 184;VAL A 171;ARG A 183;ASP A 140","LNL A1217 ( 4.1A);HXA A1215 ( 4.4A);None;None","0.99A","6hu9a-2byoA:undetectable;6hu9e-2byoA:undetectable","6cduG-2byoA:23.31;6cduH-2byoA:23.31"]]