SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'LBP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 3lvv GLUTAMATE--CYSTEINE
LIGASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 313
PHE A 474
TYR A 486
PRO A 473
 LBP  A 693 (-4.2A)
None
None
None
 1.22A 3jqaA-3lvvA:
undetectable		 3jqaA-3lvvA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 3lvv GLUTAMATE--CYSTEINE
LIGASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 313
PHE A 474
TYR A 486
PRO A 473
 LBP  A 693 (-4.2A)
None
None
None
 1.31A 3jqaB-3lvvA:
undetectable		 3jqaB-3lvvA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 3lvv GLUTAMATE--CYSTEINE
LIGASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 313
PHE A 474
TYR A 486
PRO A 473
 LBP  A 693 (-4.2A)
None
None
None
 1.19A 3jqaC-3lvvA:
undetectable		 3jqaC-3lvvA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 3lvv GLUTAMATE--CYSTEINE
LIGASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 313
PHE A 474
TYR A 486
PRO A 473
 LBP  A 693 (-4.2A)
None
None
None
 1.18A 3jqaD-3lvvA:
undetectable		 3jqaD-3lvvA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3lvv GLUTAMATE--CYSTEINE
LIGASE
(Saccharomyces
cerevisiae) 		3 / 3 TYR A 254
MET A 255
ILE A 317
 None
None
LBP  A 693 (-4.7A)
 0.83A 4c8bB-3lvvA:
undetectable		 4c8bB-3lvvA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 3lvv GLUTAMATE--CYSTEINE
LIGASE
(Saccharomyces
cerevisiae) 		5 / 10 ASP A 256
VAL A 316
GLY A 163
SER A 257
MET A 262
 None
None
PGE  A 698 (-4.4A)
None
LBP  A 693 (-3.6A)
 1.40A 4xpbA-3lvvA:
undetectable		 4xpbA-3lvvA:
20.67