SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'L6S'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		5 / 11 HIS A  53
ALA A 344
SER A 343
GLY A 282
ILE A 283
 L6S  A1610 (-4.0A)
L6S  A1610 ( 4.5A)
None
None
GLA  A1608 ( 4.7A)
 1.30A 2uxpB-4aw7A:
undetectable		 2uxpB-4aw7A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		3 / 3 HIS A  53
PHE A 368
PHE A 369
 L6S  A1610 (-4.0A)
None
None
 0.68A 3lk0D-4aw7A:
undetectable		 3lk0D-4aw7A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 4aw7 GH86A
BETA-PORPHYRANASE
(Bacteroides
plebeius) 		4 / 7 ASP A 327
SER A  54
TRP A 331
SER A  56
 None
None
L6S  A1610 (-3.8A)
None
 1.21A 4k7gB-4aw7A:
undetectable		 4k7gB-4aw7A:
20.24