SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'L41'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 353
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
None
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.66A 1fm6D-3d5fA:
36.5		 1fm6D-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 CYH A 285
HIS A 323
LEU A 356
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
None
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 1.25A 1fm6D-3d5fA:
36.5		 1fm6D-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
HIS A 323
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.64A 1fm6X-3d5fA:
35.5		 1fm6X-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		7 / 12 CYH A 285
HIS A 323
LEU A 330
LEU A 353
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.72A 1zgyA-3d5fA:
36.3		 1zgyA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 356
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
None
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 1.32A 1zgyA-3d5fA:
36.3		 1zgyA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 PHE A 282
CYH A 285
GLN A 286
HIS A 323
LEU A 330
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
None
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
 0.65A 2prgA-3d5fA:
36.1		 2prgA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 330
HIS A 449
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.77A 2prgA-3d5fA:
36.1		 2prgA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.74A 2prgB-3d5fA:
34.9		 2prgB-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 HIS A 323
LEU A 330
VAL A 334
HIS A 449
TYR A 473
 L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 1.18A 2prgB-3d5fA:
34.9		 2prgB-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 330
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.82A 2prgB-3d5fA:
34.9		 2prgB-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.88A 2xkwA-3d5fA:
36.3		 2xkwA-3d5fA:
61.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 330
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.86A 2xkwA-3d5fA:
36.3		 2xkwA-3d5fA:
61.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 ILE A 456
ALA A 371
LEU A 445
ILE A 363
MET A 453
 None
None
None
L41  A 501 ( 4.4A)
L41  A 501 ( 3.7A)
 1.20A 2xkwB-3d5fA:
33.4		 2xkwB-3d5fA:
61.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		9 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 330
LEU A 353
LYS A 367
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
None
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.85A 3adsA-3d5fA:
36.3		 3adsA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 CYH A 285
GLN A 286
LEU A 353
PHE A 360
LEU A 469
 L41  A 501 (-3.5A)
None
None
None
L41  A 501 (-3.8A)
 1.33A 3adxA-3d5fA:
36.3		 3adxA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		9 / 12 PHE A 282
CYH A 285
GLN A 286
HIS A 323
LEU A 330
LEU A 353
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
None
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.84A 3adxA-3d5fA:
36.3		 3adxA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 HIS A 323
ILE A 326
LEU A 330
LEU A 469
TYR A 473
 L41  A 501 (-3.8A)
None
L41  A 501 (-4.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 1.04A 3cs8A-3d5fA:
36.0		 3cs8A-3d5fA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 1.20A 3cs8A-3d5fA:
36.0		 3cs8A-3d5fA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 HIS A 323
LYS A 367
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.8A)
None
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 1.20A 3cs8A-3d5fA:
36.0		 3cs8A-3d5fA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 330
LEU A 353
HIS A 449
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.92A 3dzyD-3d5fA:
33.8		 3dzyD-3d5fA:
50.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 HIS A 323
LEU A 330
VAL A 334
HIS A 449
TYR A 473
 L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 1.36A 3dzyD-3d5fA:
33.8		 3dzyD-3d5fA:
50.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 330
LEU A 353
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-4.8A)
 0.92A 3dzyD-3d5fA:
33.8		 3dzyD-3d5fA:
50.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 356
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
None
L41  A 501 (-4.8A)
 1.39A 3dzyD-3d5fA:
33.8		 3dzyD-3d5fA:
50.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		4 / 7 GLN A 286
LEU A 330
VAL A 341
LYS A 367
 None
L41  A 501 (-4.9A)
L41  A 501 ( 4.4A)
None
 0.88A 3g8iA-3d5fA:
38.0		 3g8iA-3d5fA:
70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		4 / 7 GLN A 286
VAL A 341
LYS A 367
LEU A 469
 None
L41  A 501 ( 4.4A)
None
L41  A 501 (-3.8A)
 0.56A 3g8iA-3d5fA:
38.0		 3g8iA-3d5fA:
70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 7 LEU A 255
GLN A 286
LEU A 330
VAL A 341
LEU A 353
 None
None
L41  A 501 (-4.9A)
L41  A 501 ( 4.4A)
None
 0.70A 3g8iA-3d5fA:
38.0		 3g8iA-3d5fA:
70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 7 LEU A 255
GLN A 286
VAL A 341
LEU A 353
LEU A 469
 None
None
L41  A 501 ( 4.4A)
None
L41  A 501 (-3.8A)
 0.60A 3g8iA-3d5fA:
38.0		 3g8iA-3d5fA:
70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		7 / 12 CYH A 285
HIS A 323
LEU A 330
LYS A 367
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.65A 3g9eA-3d5fA:
37.0		 3g9eA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 HIS A 323
LEU A 330
VAL A 334
LYS A 367
HIS A 449
TYR A 473
 L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 1.39A 3g9eA-3d5fA:
37.0		 3g9eA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		10 / 10 VAL A 281
PHE A 282
GLN A 286
ILE A 326
MET A 329
LEU A 339
VAL A 341
VAL A 348
LEU A 353
LYS A 367
 L41  A 501 ( 4.7A)
L41  A 501 ( 4.9A)
None
None
None
L41  A 501 (-4.8A)
L41  A 501 ( 4.4A)
None
None
None
 0.40A 3gwxA-3d5fA:
39.9		 3gwxA-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 10 VAL A 281
PHE A 360
LEU A 339
VAL A 341
VAL A 348
LEU A 353
 L41  A 501 ( 4.7A)
None
L41  A 501 (-4.8A)
L41  A 501 ( 4.4A)
None
None
 1.31A 3gwxA-3d5fA:
39.9		 3gwxA-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 CYH A 285
THR A 288
LEU A 339
ILE A 363
ILE A 364
 L41  A 501 (-3.5A)
L41  A 501 (-3.0A)
L41  A 501 (-4.8A)
L41  A 501 ( 4.4A)
L41  A 501 ( 4.2A)
 1.20A 3gwxA-3d5fA:
39.9		 3gwxA-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		12 / 12 CYH A 285
THR A 288
THR A 289
THR A 292
HIS A 323
LEU A 330
ILE A 363
ILE A 364
HIS A 449
MET A 453
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.0A)
L41  A 501 (-3.5A)
None
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 ( 4.4A)
L41  A 501 ( 4.2A)
L41  A 501 (-3.9A)
L41  A 501 ( 3.7A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.54A 3gwxA-3d5fA:
39.9		 3gwxA-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		12 / 12 CYH A 285
THR A 288
THR A 289
THR A 292
GLU A 295
HIS A 323
LEU A 330
ILE A 333
LYS A 367
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.0A)
L41  A 501 (-3.5A)
None
None
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
None
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.46A 3gwxB-3d5fA:
38.2		 3gwxB-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 GLU A 291
HIS A 323
LEU A 330
LYS A 367
HIS A 449
TYR A 473
 None
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 1.16A 3gwxB-3d5fA:
38.2		 3gwxB-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		12 / 12 LEU A 255
PHE A 282
ARG A 284
GLN A 286
ILE A 326
MET A 329
LEU A 339
VAL A 341
VAL A 348
LEU A 353
ILE A 364
MET A 453
 None
L41  A 501 ( 4.9A)
None
None
None
None
L41  A 501 (-4.8A)
L41  A 501 ( 4.4A)
None
None
L41  A 501 ( 4.2A)
L41  A 501 ( 3.7A)
 0.71A 3gwxB-3d5fA:
38.2		 3gwxB-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 360
LEU A 339
VAL A 341
VAL A 348
LEU A 353
ILE A 364
 None
L41  A 501 (-4.8A)
L41  A 501 ( 4.4A)
None
None
L41  A 501 ( 4.2A)
 1.25A 3gwxB-3d5fA:
38.2		 3gwxB-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
THR A 288
ILE A 363
HIS A 449
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.0A)
L41  A 501 ( 4.4A)
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.90A 3sp6A-3d5fA:
37.1		 3sp6A-3d5fA:
70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
THR A 288
VAL A 341
HIS A 449
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.0A)
L41  A 501 ( 4.4A)
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.51A 3sp6A-3d5fA:
37.1		 3sp6A-3d5fA:
70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		12 / 12 LEU A 255
PHE A 282
CYH A 285
THR A 288
THR A 289
HIS A 323
ILE A 326
LEU A 339
VAL A 348
ILE A 364
HIS A 449
TYR A 473
 None
L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.0A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
None
L41  A 501 (-4.8A)
None
L41  A 501 ( 4.2A)
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.96A 3sp9A-3d5fA:
38.6		 3sp9A-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		12 / 12 LEU A 255
VAL A 281
PHE A 282
CYH A 285
THR A 288
THR A 289
HIS A 323
ILE A 326
LEU A 339
VAL A 348
HIS A 449
TYR A 473
 None
L41  A 501 ( 4.7A)
L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.0A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
None
L41  A 501 (-4.8A)
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.97A 3sp9B-3d5fA:
38.7		 3sp9B-3d5fA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		7 / 12 PHE A 282
CYH A 285
ILE A 326
LEU A 330
LEU A 353
HIS A 449
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
None
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.61A 3vn2A-3d5fA:
36.9		 3vn2A-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.75A 4emaA-3d5fA:
35.7		 4emaA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 CYH A 285
HIS A 323
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.76A 4o8fA-3d5fA:
34.3		 4o8fA-3d5fA:
62.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.61A 4o8fA-3d5fA:
34.3		 4o8fA-3d5fA:
62.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.62A 4o8fB-3d5fA:
33.6		 4o8fB-3d5fA:
62.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 HIS A 323
LEU A 330
VAL A 334
HIS A 449
TYR A 473
 L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
None
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 1.13A 4o8fB-3d5fA:
33.6		 4o8fB-3d5fA:
62.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 ILE A 249
THR A 292
THR A 288
LEU A 330
LEU A 339
 None
None
L41  A 501 (-3.0A)
L41  A 501 (-4.9A)
L41  A 501 (-4.8A)
 1.37A 4qynB-3d5fA:
undetectable		 4qynB-3d5fA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 TYR A 473
VAL A 315
LEU A 296
LEU A 469
LEU A 465
 L41  A 501 (-4.8A)
None
None
L41  A 501 (-3.8A)
None
 1.36A 4rtbA-3d5fA:
undetectable		 4rtbA-3d5fA:
21.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		7 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.65A 4xldA-3d5fA:
36.5		 4xldA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		8 / 12 PHE A 282
CYH A 285
HIS A 323
ILE A 326
HIS A 449
LEU A 465
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
None
L41  A 501 (-3.9A)
None
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.85A 4xumA-3d5fA:
36.2		 4xumA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.73A 5ji0D-3d5fA:
36.3		 5ji0D-3d5fA:
62.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.63A 5y2oA-3d5fA:
36.5		 5y2oA-3d5fA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 330
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.70A 5y2oA-3d5fA:
36.5		 5y2oA-3d5fA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 LEU A 255
PHE A 282
CYH A 285
GLN A 286
LEU A 330
 None
L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
None
L41  A 501 (-4.9A)
 0.60A 5y2tA-3d5fA:
35.9		 5y2tA-3d5fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 LEU A 255
CYH A 285
GLN A 286
ILE A 326
LEU A 330
HIS A 449
 None
L41  A 501 (-3.5A)
None
None
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
 0.75A 5y2tB-3d5fA:
34.3		 5y2tB-3d5fA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		4 / 6 CYH A 285
HIS A 323
HIS A 449
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.60A 5ycnA-3d5fA:
36.7		 5ycnA-3d5fA:
62.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		4 / 6 PHE A 282
CYH A 285
HIS A 323
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.64A 5ycnA-3d5fA:
36.7		 5ycnA-3d5fA:
62.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		6 / 12 CYH A 285
HIS A 323
LEU A 330
HIS A 449
LEU A 469
TYR A 473
 L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.67A 5ycpA-3d5fA:
37.1		 5ycpA-3d5fA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		5 / 12 PHE A 282
CYH A 285
HIS A 323
LEU A 469
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
L41  A 501 (-3.8A)
L41  A 501 (-3.8A)
L41  A 501 (-4.8A)
 0.72A 5ycpA-3d5fA:
37.1		 5ycpA-3d5fA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens) 		7 / 12 PHE A 282
CYH A 285
GLN A 286
HIS A 323
LEU A 330
HIS A 449
TYR A 473
 L41  A 501 ( 4.9A)
L41  A 501 (-3.5A)
None
L41  A 501 (-3.8A)
L41  A 501 (-4.9A)
L41  A 501 (-3.9A)
L41  A 501 (-4.8A)
 0.78A 6md4A-3d5fA:
36.0		 6md4A-3d5fA:
15.79