SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'L3P'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3a7k HALORHODOPSIN
(Natronomonas
pharaonis) 		5 / 12 LEU A 135
LEU A 138
LEU A 141
ALA A 142
LEU A 195
 None
None
None
None
L3P  A 331 (-3.7A)
 0.52A 1ya3C-3a7kA:
undetectable		 1ya3C-3a7kA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3a7k HALORHODOPSIN
(Natronomonas
pharaonis) 		5 / 11 TRP A 246
SER A  37
VAL A 233
GLY A 235
VAL A 228
 L3P  A 333 (-3.6A)
None
None
None
None
 1.26A 6hu9A-3a7kA:
2.5
6hu9E-3a7kA:
0.0
6hu9I-3a7kA:
undetectable		 6hu9A-3a7kA:
20.28
6hu9E-3a7kA:
21.25
6hu9I-3a7kA:
12.97