SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'KR0'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 5fq6 SUSC/RAGA FAMILY
TONB-LINKED OUTER
MEMBRANE PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 GLN B 459
ASP B 460
LEU B 101
ASN B 483
 KR0  B1985 (-3.6A)
None
None
None
 1.26A 1ig3A-5fq6B:
undetectable
1ig3B-5fq6B:
undetectable		 1ig3A-5fq6B:
14.81
1ig3B-5fq6B:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5fq6 SUSC/RAGA FAMILY
TONB-LINKED OUTER
MEMBRANE PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE B 457
VAL B 487
ARG B 485
ASP B 597
 KR0  B1985 (-4.0A)
None
None
None
 1.00A 6hu9a-5fq6B:
undetectable
6hu9e-5fq6B:
undetectable		 6hu9a-5fq6B:
21.61
6hu9e-5fq6B:
9.98