SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'KPI'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AEG_A_4APA296_1 (CYTOCHROME C PEROXIDASE)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	4 / 8	LYS A 35 THR A 36 GLY A 68 LEU A 84	None None KPI A 184 ( 3.5A) None	0.74A	1aegA-4hnnA: undetectable	1aegA-4hnnA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_A_FOLA605_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.90A	1qzfA-5ktlA: undetectable	1qzfA-5ktlA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_B_FOLB609_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.90A	1qzfB-5ktlA: undetectable	1qzfB-5ktlA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_C_FOLC613_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.90A	1qzfC-5ktlA: undetectable	1qzfC-5ktlA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_D_FOLD617_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.90A	1qzfD-5ktlA: undetectable	1qzfD-5ktlA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_E_FOLE621_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.90A	1qzfE-5ktlA: undetectable	1qzfE-5ktlA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R5L_A_VIVA301_0 (PROTEIN (ALPHA-TOCOPHEROL TRANSFER PROTEIN))	3a5f	DIHYDRODIPICOLINATE SYNTHASE (Clostridium botulinum)	5 / 12	ILE A 29 ILE A 132 ILE A 75 VAL A 68 ILE A 3	None KPI A 162 ( 4.8A) None None None	1.01A	1r5lA-3a5fA: 1.5	1r5lA-3a5fA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SH9_B_RITB301_2 (POL POLYPROTEIN)	3fkr	L-2-KETO-3-DEOXYARAB ONATE DEHYDRATASE (Azospirillum brasilense)	5 / 10	GLY A 222 ASP A 208 ILE A 183 GLY A 205 ALA A 165	None None KPI A 182 ( 3.8A) None None	0.95A	1sh9B-3fkrA: undetectable	1sh9B-3fkrA: 14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_0 (SUN PROTEIN)	3hij	DIHYDRODIPICOLINATE SYNTHASE (Bacillus anthracis)	5 / 12	ALA A 10 GLY A 45 GLY A 44 ILE A 7 GLY A 5	KPI A 163 ( 3.2A) KPI A 163 ( 3.4A) None None None	0.97A	1sqfA-3hijA: undetectable	1sqfA-3hijA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VQ1_A_SAMA301_0 (N5-GLUTAMINE METHYLTRANSFERASE, HEMK)	3a5f	DIHYDRODIPICOLINATE SYNTHASE (Clostridium botulinum)	5 / 12	ILE A 61 GLY A 47 ALA A 10 ILE A 41 GLU A 54	None None KPI A 162 ( 3.4A) None None	1.47A	1vq1A-3a5fA: undetectable	1vq1A-3a5fA: 22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VQ1_A_SAMA301_0 (N5-GLUTAMINE METHYLTRANSFERASE, HEMK)	3a5f	DIHYDRODIPICOLINATE SYNTHASE (Clostridium botulinum)	5 / 12	ILE A 61 GLY A 47 ALA A 10 ILE A 41 GLU A 59	None None KPI A 162 ( 3.4A) None None	1.43A	1vq1A-3a5fA: undetectable	1vq1A-3a5fA: 22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVS_B_MK1B902_3 (POL POLYPROTEIN)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	5 / 12	GLY A 221 ILE A 25 GLY A 182 VAL A 183 ILE A 31	None None None KPI A 184 ( 2.9A) None	0.92A	2avsB-4hnnA: undetectable	2avsB-4hnnA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_B_SAMB2002_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	4 / 7	TYR A 156 GLY A 68 THR A 69 ASN A 101	KPI A 184 ( 3.8A) KPI A 184 ( 3.5A) KPI A 184 ( 4.3A) None	1.07A	2g70B-4hnnA: undetectable	2g70B-4hnnA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_A_MTXA605_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	1.06A	2oipA-5ktlA: undetectable	2oipA-5ktlA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_D_MTXD617_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.93A	2oipD-5ktlA: undetectable	2oipD-5ktlA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_E_MTXE621_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.83A	2oipE-5ktlA: undetectable	2oipE-5ktlA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UVN_A_ECNA1409_1 (CYTOCHROME P450 130)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	5 / 12	LEU A 270 PRO A 263 THR A 70 GLY A 71 GLY A 67	None None KPI A 184 ( 3.8A) None None	1.12A	2uvnA-4hnnA: undetectable	2uvnA-4hnnA: 22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMA_A_ACAA502_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	5ud6	DIHYDRODIPICOLINATE SYNTHASE (Cyanidioschyzon merolae)	5 / 11	TYR A 145 PHE A 258 ASN A 262 GLY A 149 ILE A 147	KPI A 174 ( 3.7A) None None None None	1.50A	2zmaA-5ud6A: undetectable	2zmaA-5ud6A: 13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E00_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	4pfm	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Shewanella benthica)	5 / 12	ILE A 74 ALA A 38 ASN A 3 ALA A 8 ILE A 158	None None None KPI A 161 ( 3.4A) None	1.04A	3e00A-4pfmA: undetectable	3e00A-4pfmA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HGX_A_SALA102_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	4fha	DIHYDRODIPICOLINATE SYNTHASE (Streptococcus pneumoniae)	4 / 7	MET A 155 ILE A 139 TYR A 140 ILE A 138	None None KPI A 168 ( 3.8A) None	0.99A	3hgxA-4fhaA: undetectable	3hgxA-4fhaA: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_B_MTXB609_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	1.07A	3hj3B-5ktlA: undetectable	3hj3B-5ktlA: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_D_MTXD615_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 246 LEU A 212 THR A 47 ILE A 12 LEU A 29	None None KPI A 164 ( 3.5A) None None	0.93A	3hj3D-5ktlA: undetectable	3hj3D-5ktlA: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NU5_B_478B401_2 (PROTEASE)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	5 / 12	GLY A 221 ILE A 25 GLY A 182 VAL A 183 ILE A 31	None None None KPI A 184 ( 2.9A) None	0.95A	3nu5B-4hnnA: undetectable	3nu5B-4hnnA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_C_DR7C100_1 (HIV-1 PROTEASE)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	5 / 12	GLY A 221 ILE A 25 GLY A 182 VAL A 183 ILE A 31	None None None KPI A 184 ( 2.9A) None	0.87A	3oxxC-4hnnA: undetectable	3oxxC-4hnnA: 17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFU_A_RBVA601_1 (RNA POLYMERASE)	5ud6	DIHYDRODIPICOLINATE SYNTHASE (Cyanidioschyzon merolae)	5 / 9	ASP A 201 THR A 16 TYR A 145 GLY A 199 ASP A 200	None None KPI A 174 ( 3.7A) KPI A 174 ( 3.8A) None	1.35A	3sfuA-5ud6A: undetectable	3sfuA-5ud6A: 9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_B_TPVB100_1 (HIV-1 PROTEASE)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	5 / 9	LEU A 266 ASN A 262 VAL A 254 GLY A 205 ILE A 223	None None None KPI A 184 ( 4.3A) KPI A 184 ( 3.5A)	1.23A	3spkA-4hnnA: undetectable	3spkA-4hnnA: 17.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BWL_C_MN9C1297_0 (N-ACETYLNEURAMINATE LYASE)	4imd	N-ACETYLNEURAMINATE LYASE (Pasteurella multocida)	8 / 10	ILE A 138 LEU A 141 THR A 166 GLY A 188 ASP A 190 GLU A 191 GLY A 206 SER A 207	None None None KPI A 164 ( 4.4A) EDO A 303 (-3.4A) EDO A 303 (-3.4A) KPI A 164 ( 4.2A) EDO A 303 ( 4.0A)	0.50A	4bwlC-4imdA: 42.2	4bwlC-4imdA: 36.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7C_D_ACTD504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	4nq1	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Legionella pneumophila)	3 / 3	GLY A 185 SER A 184 TRP A 193	KPI A 160 ( 3.8A) None None	0.97A	4e7cD-4nq1A: undetectable	4e7cD-4nq1A: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_B_CQAB301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	4 / 8	GLY A 68 GLY A 100 VAL A 154 TYR A 156	KPI A 184 ( 3.5A) None None KPI A 184 ( 3.8A)	0.71A	4fgzB-4hnnA: undetectable	4fgzB-4hnnA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9Q_A_9TPA601_1 (SERUM ALBUMIN)	5ktl	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Trichormus variabilis)	5 / 12	LEU A 154 ILE A 124 HIS A 120 LEU A 134 GLY A 80	None None None KPI A 164 ( 4.8A) None	1.28A	4l9qA-5ktlA: undetectable	4l9qA-5ktlA: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_A_ACTA1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	3hij	DIHYDRODIPICOLINATE SYNTHASE (Bacillus anthracis)	4 / 5	GLY A 166 ALA A 165 GLY A 139 PRO A 138	None KPI A 163 ( 4.9A) None None	0.91A	4u9uA-3hijA: undetectable	4u9uA-3hijA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_B_ACTB1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	3hij	DIHYDRODIPICOLINATE SYNTHASE (Bacillus anthracis)	4 / 5	GLY A 166 ALA A 165 GLY A 139 PRO A 138	None KPI A 163 ( 4.9A) None None	0.90A	4u9uB-3hijA: undetectable	4u9uB-3hijA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE0_A_40LA1101_0 (PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM)	4hnn	DIHYDRODIPICOLINATE SYNTHASE (Vitis vinifera)	5 / 12	PRO A 231 TYR A 49 THR A 70 ASN A 262 ILE A 34	None None KPI A 184 ( 3.8A) None None	1.37A	4xe0A-4hnnA: undetectable	4xe0A-4hnnA: 15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IEN_A_VDYA201_1 (CDL2.2)	4fha	DIHYDRODIPICOLINATE SYNTHASE (Streptococcus pneumoniae)	5 / 12	LEU A 57 LEU A 262 MET A 265 ALA A 14 LEU A 37	None None None KPI A 168 ( 3.5A) None	1.32A	5ienA-4fhaA: undetectable	5ienA-4fhaA: 17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_B_ACRB1421_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	3fkr	L-2-KETO-3-DEOXYARAB ONATE DEHYDRATASE (Azospirillum brasilense)	4 / 6	MET A 152 GLU A 184 GLY A 225 GLY A 22	KPI A 182 ( 3.9A) NA A 409 ( 2.1A) None None	0.92A	5x7pB-3fkrA: undetectable	5x7pB-3fkrA: 12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y2T_A_8LXA501_0 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	4nq1	4-HYDROXY-TETRAHYDRO DIPICOLINATE SYNTHASE (Legionella pneumophila)	5 / 12	LEU A 87 GLY A 42 LEU A 23 ILE A 59 LEU A 265	None KPI A 160 ( 3.5A) None None None	1.19A	5y2tA-4nq1A: undetectable	5y2tA-4nq1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_A_SAMA501_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	3hij	DIHYDRODIPICOLINATE SYNTHASE (Bacillus anthracis)	5 / 12	GLY A 188 ILE A 204 THR A 193 ILE A 175 ILE A 162	KPI A 163 ( 3.9A) None None None KPI A 163 ( 3.7A)	0.97A	6emuA-3hijA: 2.7	6emuA-3hijA: 19.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AEG_A_4APA296_1","CYTOCHROME C PEROXIDASE","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",4,"LYS A  35;THR A  36;GLY A  68;LEU A  84","None;None;KPI A 184 ( 3.5A);None","0.74A","1aegA-4hnnA:undetectable",null],["1QZF_A_FOLA605_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.90A","1qzfA-5ktlA:undetectable","1aegA-4hnnA:22.76"],["1QZF_B_FOLB609_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.90A","1qzfB-5ktlA:undetectable","1qzfA-5ktlA:20.73"],["1QZF_C_FOLC613_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.90A","1qzfC-5ktlA:undetectable","1qzfB-5ktlA:20.73"],["1QZF_D_FOLD617_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.90A","1qzfD-5ktlA:undetectable","1qzfC-5ktlA:20.73"],["1QZF_E_FOLE621_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.90A","1qzfE-5ktlA:undetectable","1qzfD-5ktlA:20.73"],["1R5L_A_VIVA301_0","PROTEIN (ALPHA-TOCOPHEROL TRANSFER PROTEIN)","3a5f","DIHYDRODIPICOLINATE SYNTHASE","Clostridium botulinum",5,"ILE A  29;ILE A 132;ILE A  75;VAL A  68;ILE A   3","None;KPI A 162 ( 4.8A);None;None;None","1.01A","1r5lA-3a5fA:1.5","1qzfE-5ktlA:20.73"],["1SH9_B_RITB301_2","POL POLYPROTEIN","3fkr","L-2-KETO-3-DEOXYARABONATE DEHYDRATASE","Azospirillum brasilense",5,"GLY A 222;ASP A 208;ILE A 183;GLY A 205;ALA A 165","None;None;KPI A 182 ( 3.8A);None;None","0.95A","1sh9B-3fkrA:undetectable","1r5lA-3a5fA:23.40"],["1SQF_A_SAMA430_0","SUN PROTEIN","3hij","DIHYDRODIPICOLINATE SYNTHASE","Bacillus anthracis",5,"ALA A  10;GLY A  45;GLY A  44;ILE A   7;GLY A   5","KPI A 163 ( 3.2A);KPI A 163 ( 3.4A);None;None;None","0.97A","1sqfA-3hijA:undetectable","1sh9B-3fkrA:14.90"],["1VQ1_A_SAMA301_0","N5-GLUTAMINE METHYLTRANSFERASE, HEMK","3a5f","DIHYDRODIPICOLINATE SYNTHASE","Clostridium botulinum",5,"ILE A  61;GLY A  47;ALA A  10;ILE A  41;GLU A  54","None;None;KPI A 162 ( 3.4A);None;None","1.47A","1vq1A-3a5fA:undetectable","1sqfA-3hijA:21.18"],["1VQ1_A_SAMA301_0","N5-GLUTAMINE METHYLTRANSFERASE, HEMK","3a5f","DIHYDRODIPICOLINATE SYNTHASE","Clostridium botulinum",5,"ILE A  61;GLY A  47;ALA A  10;ILE A  41;GLU A  59","None;None;KPI A 162 ( 3.4A);None;None","1.43A","1vq1A-3a5fA:undetectable","1vq1A-3a5fA:22.96"],["2AVS_B_MK1B902_3","POL POLYPROTEIN","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",5,"GLY A 221;ILE A  25;GLY A 182;VAL A 183;ILE A  31","None;None;None;KPI A 184 ( 2.9A);None","0.92A","2avsB-4hnnA:undetectable","1vq1A-3a5fA:22.96"],["2G70_B_SAMB2002_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",4,"TYR A 156;GLY A  68;THR A  69;ASN A 101","KPI A 184 ( 3.8A);KPI A 184 ( 3.5A);KPI A 184 ( 4.3A);None","1.07A","2g70B-4hnnA:undetectable","2avsB-4hnnA:15.38"],["2OIP_A_MTXA605_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","1.06A","2oipA-5ktlA:undetectable","2g70B-4hnnA:22.35"],["2OIP_D_MTXD617_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.93A","2oipD-5ktlA:undetectable","2oipA-5ktlA:20.62"],["2OIP_E_MTXE621_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.83A","2oipE-5ktlA:undetectable","2oipD-5ktlA:20.62"],["2UVN_A_ECNA1409_1","CYTOCHROME P450 130","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",5,"LEU A 270;PRO A 263;THR A  70;GLY A  71;GLY A  67","None;None;KPI A 184 ( 3.8A);None;None","1.12A","2uvnA-4hnnA:undetectable","2oipE-5ktlA:20.62"],["2ZMA_A_ACAA502_1","6-AMINOHEXANOATE-DIMER HYDROLASE","5ud6","DIHYDRODIPICOLINATE SYNTHASE","Cyanidioschyzon merolae",5,"TYR A 145;PHE A 258;ASN A 262;GLY A 149;ILE A 147","KPI A 174 ( 3.7A);None;None;None;None","1.50A","2zmaA-5ud6A:undetectable","2uvnA-4hnnA:22.48"],["3E00_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","4pfm","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Shewanella benthica",5,"ILE A  74;ALA A  38;ASN A   3;ALA A   8;ILE A 158","None;None;None;KPI A 161 ( 3.4A);None","1.04A","3e00A-4pfmA:undetectable","2zmaA-5ud6A:13.35"],["3HGX_A_SALA102_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB","4fha","DIHYDRODIPICOLINATE SYNTHASE","Streptococcus pneumoniae",4,"MET A 155;ILE A 139;TYR A 140;ILE A 138","None;None;KPI A 168 ( 3.8A);None","0.99A","3hgxA-4fhaA:undetectable","3e00A-4pfmA:21.12"],["3HJ3_B_MTXB609_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","1.07A","3hj3B-5ktlA:undetectable","3hgxA-4fhaA:17.04"],["3HJ3_D_MTXD615_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 246;LEU A 212;THR A  47;ILE A  12;LEU A  29","None;None;KPI A 164 ( 3.5A);None;None","0.93A","3hj3D-5ktlA:undetectable","3hj3B-5ktlA:20.92"],["3NU5_B_478B401_2","PROTEASE","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",5,"GLY A 221;ILE A  25;GLY A 182;VAL A 183;ILE A  31","None;None;None;KPI A 184 ( 2.9A);None","0.95A","3nu5B-4hnnA:undetectable","3hj3D-5ktlA:20.92"],["3OXX_C_DR7C100_1","HIV-1 PROTEASE","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",5,"GLY A 221;ILE A  25;GLY A 182;VAL A 183;ILE A  31","None;None;None;KPI A 184 ( 2.9A);None","0.87A","3oxxC-4hnnA:undetectable","3nu5B-4hnnA:15.38"],["3SFU_A_RBVA601_1","RNA POLYMERASE","5ud6","DIHYDRODIPICOLINATE SYNTHASE","Cyanidioschyzon merolae",5,"ASP A 201;THR A  16;TYR A 145;GLY A 199;ASP A 200","None;None;KPI A 174 ( 3.7A);KPI A 174 ( 3.8A);None","1.35A","3sfuA-5ud6A:undetectable","3oxxC-4hnnA:17.58"],["3SPK_B_TPVB100_1","HIV-1 PROTEASE;HIV-1 PROTEASE","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",5,"LEU A 266;ASN A 262;VAL A 254;GLY A 205;ILE A 223","None;None;None;KPI A 184 ( 4.3A);KPI A 184 ( 3.5A)","1.23A","3spkA-4hnnA:undetectable","3sfuA-5ud6A:9.71"],["4BWL_C_MN9C1297_0","N-ACETYLNEURAMINATE LYASE","4imd","N-ACETYLNEURAMINATE LYASE","Pasteurella multocida",8,"ILE A 138;LEU A 141;THR A 166;GLY A 188;ASP A 190;GLU A 191;GLY A 206;SER A 207","None;None;None;KPI A 164 ( 4.4A);EDO A 303 (-3.4A);EDO A 303 (-3.4A);KPI A 164 ( 4.2A);EDO A 303 ( 4.0A)","0.50A","4bwlC-4imdA:42.2","3spkA-4hnnA:17.76"],["4E7C_D_ACTD504_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","4nq1","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Legionella pneumophila",3,"GLY A 185;SER A 184;TRP A 193","KPI A 160 ( 3.8A);None;None","0.97A","4e7cD-4nq1A:undetectable","4bwlC-4imdA:36.27"],["4FGZ_B_CQAB301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",4,"GLY A  68;GLY A 100;VAL A 154;TYR A 156","KPI A 184 ( 3.5A);None;None;KPI A 184 ( 3.8A)","0.71A","4fgzB-4hnnA:undetectable","4e7cD-4nq1A:23.08"],["4L9Q_A_9TPA601_1","SERUM ALBUMIN","5ktl","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Trichormus variabilis",5,"LEU A 154;ILE A 124;HIS A 120;LEU A 134;GLY A  80","None;None;None;KPI A 164 ( 4.8A);None","1.28A","4l9qA-5ktlA:undetectable","4fgzB-4hnnA:20.23"],["4U9U_A_ACTA1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","3hij","DIHYDRODIPICOLINATE SYNTHASE","Bacillus anthracis",4,"GLY A 166;ALA A 165;GLY A 139;PRO A 138","None;KPI A 163 ( 4.9A);None;None","0.91A","4u9uA-3hijA:undetectable","4l9qA-5ktlA:18.95"],["4U9U_B_ACTB1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","3hij","DIHYDRODIPICOLINATE SYNTHASE","Bacillus anthracis",4,"GLY A 166;ALA A 165;GLY A 139;PRO A 138","None;KPI A 163 ( 4.9A);None;None","0.90A","4u9uB-3hijA:undetectable","4u9uA-3hijA:22.82"],["4XE0_A_40LA1101_0","PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM","4hnn","DIHYDRODIPICOLINATE SYNTHASE","Vitis vinifera",5,"PRO A 231;TYR A  49;THR A  70;ASN A 262;ILE A  34","None;None;KPI A 184 ( 3.8A);None;None","1.37A","4xe0A-4hnnA:undetectable","4u9uB-3hijA:22.82"],["5IEN_A_VDYA201_1","CDL2.2","4fha","DIHYDRODIPICOLINATE SYNTHASE","Streptococcus pneumoniae",5,"LEU A  57;LEU A 262;MET A 265;ALA A  14;LEU A  37","None;None;None;KPI A 168 ( 3.5A);None","1.32A","5ienA-4fhaA:undetectable","4xe0A-4hnnA:15.63"],["5X7P_B_ACRB1421_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","3fkr","L-2-KETO-3-DEOXYARABONATE DEHYDRATASE","Azospirillum brasilense",4,"MET A 152;GLU A 184;GLY A 225;GLY A  22","KPI A 182 ( 3.9A); NA A 409 ( 2.1A);None;None","0.92A","5x7pB-3fkrA:undetectable","5ienA-4fhaA:17.95"],["5Y2T_A_8LXA501_0","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","4nq1","4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE","Legionella pneumophila",5,"LEU A  87;GLY A  42;LEU A  23;ILE A  59;LEU A 265","None;KPI A 160 ( 3.5A);None;None;None","1.19A","5y2tA-4nq1A:undetectable","5x7pB-3fkrA:12.47"],["6EMU_A_SAMA501_0","TRNA (GUANINE(9)-\/ADENINE(9)-N1)-METHYLTRANSFERASE","3hij","DIHYDRODIPICOLINATE SYNTHASE","Bacillus anthracis",5,"GLY A 188;ILE A 204;THR A 193;ILE A 175;ILE A 162","KPI A 163 ( 3.9A);None;None;None;KPI A 163 ( 3.7A)","0.97A","6emuA-3hijA:2.7","5y2tA-4nq1A:undetectable"]]