SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'KDO'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_B_STRB2001_1 (MINERALOCORTICOID RECEPTOR)	4pf6	C4-DICARBOXYLATE-BIN DING PROTEIN (Roseobacter denitrificans)	5 / 12	GLN A 91 LEU A 239 MET A 124 LEU A 139 THR A 130	KDO A 401 ( 4.6A) None None None None	1.35A	1ya3B-4pf6A: undetectable	1ya3B-4pf6A: 23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_B_30BB500_2 (GENOME POLYPROTEIN)	3dur	ANTIBODY FV FRAGMENT SAG173-04 (Mus musculus)	3 / 3	PHE A 71 TYR A 92 LEU A 47	None KDO A 303 (-4.9A) None	0.72A	3keeB-3durA: undetectable	3keeB-3durA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_B_SAMB300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	3duu	IG-LIKE PROTEIN (Mus musculus)	3 / 3	TYR B 97 ASP B 100 ASP B 101	PG4 B 115 ( 4.5A) KDO B 114 (-4.1A) None	0.89A	3ou7B-3duuB: undetectable	3ou7B-3duuB: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_B_SUEB1201_2 (NS3 PROTEASE, NS4A PROTEIN)	3dur	ANTIBODY FV FRAGMENT SAG173-04 (Mus musculus)	3 / 3	PHE A 71 TYR A 92 LEU A 47	None KDO A 303 (-4.9A) None	0.75A	3sueB-3durA: undetectable	3sueB-3durA: 19.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YA3_B_STRB2001_1","MINERALOCORTICOID RECEPTOR","4pf6","C4-DICARBOXYLATE-BINDING PROTEIN","Roseobacter denitrificans",5,"GLN A  91;LEU A 239;MET A 124;LEU A 139;THR A 130","KDO A 401 ( 4.6A);None;None;None;None","1.35A","1ya3B-4pf6A:undetectable",null],["3KEE_B_30BB500_2","GENOME POLYPROTEIN","3dur","ANTIBODY FV FRAGMENT SAG173-04","Mus musculus",3,"PHE A  71;TYR A  92;LEU A  47","None;KDO A 303 (-4.9A);None","0.72A","3keeB-3durA:undetectable","1ya3B-4pf6A:23.60"],["3OU7_B_SAMB300_1","SAM-DEPENDENT METHYLTRANSFERASE","3duu","IG-LIKE PROTEIN","Mus musculus",3,"TYR B  97;ASP B 100;ASP B 101","PG4 B 115 ( 4.5A);KDO B 114 (-4.1A);None","0.89A","3ou7B-3duuB:undetectable","3keeB-3durA:18.32"],["3SUE_B_SUEB1201_2","NS3 PROTEASE, NS4A PROTEIN","3dur","ANTIBODY FV FRAGMENT SAG173-04","Mus musculus",3,"PHE A  71;TYR A  92;LEU A  47","None;KDO A 303 (-4.9A);None","0.75A","3sueB-3durA:undetectable","3ou7B-3duuB:21.43"]]