SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'KDF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 ARG A 108
GLY A   8
GLU A   9
SER A 134
ILE A  53
 KDF  A1314 ( 3.0A)
None
None
None
None
 1.45A 1odiB-2varA:
undetectable		 1odiB-2varA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 ARG A 108
GLY A   8
GLU A   9
SER A 134
ILE A  53
 KDF  A1314 ( 3.0A)
None
None
None
None
 1.44A 1odiC-2varA:
undetectable		 1odiC-2varA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 ARG A 108
GLY A   8
GLU A   9
SER A 134
ILE A  53
 KDF  A1314 ( 3.0A)
None
None
None
None
 1.43A 1odiD-2varA:
undetectable		 1odiD-2varA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 ARG A 108
GLY A   8
GLU A   9
SER A 134
ILE A  53
 KDF  A1314 ( 3.0A)
None
None
None
None
 1.41A 1odiE-2varA:
undetectable		 1odiE-2varA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 ARG A 108
GLY A   8
GLU A   9
SER A 134
ILE A  53
 KDF  A1314 ( 3.0A)
None
None
None
None
 1.40A 1odiF-2varA:
undetectable		 1odiF-2varA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 8 ARG A 108
GLY A   8
GLU A   9
SER A 134
ILE A  53
 KDF  A1314 ( 3.0A)
None
None
None
None
 1.28A 1pk7B-2varA:
undetectable		 1pk7B-2varA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 ILE A  12
ASN A  38
ILE A  41
TYR A  90
THR A  87
 None
KDF  A1314 ( 4.2A)
None
KDF  A1314 ( 4.0A)
None
 1.16A 2blaA-2varA:
undetectable		 2blaA-2varA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		4 / 8 GLY A  34
ASP A 258
THR A 135
ILE A 137
 KDG  A1313 ( 3.3A)
KDF  A1314 (-2.8A)
None
KDG  A1313 ( 3.3A)
 0.96A 2f9wA-2varA:
undetectable
2f9wB-2varA:
undetectable		 2f9wA-2varA:
22.19
2f9wB-2varA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		6 / 12 GLY A  34
SER A  35
ASN A  38
GLU A  36
GLY A 255
ASP A 258
 KDG  A1313 ( 3.3A)
KDG  A1313 ( 3.8A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 (-3.0A)
KDF  A1314 (-2.8A)
 0.73A 3uboA-2varA:
35.9		 3uboA-2varA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.76A 3uboB-2varA:
36.8		 3uboB-2varA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.69A 4e3aA-2varA:
36.8		 4e3aA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		6 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
GLY A 255
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
ANP  A1315 (-3.0A)
KDF  A1314 (-2.8A)
 0.65A 4e3aB-2varA:
36.8		 4e3aB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
THR A 254
GLY A 255
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
ANP  A1315 ( 4.6A)
ANP  A1315 (-3.0A)
KDF  A1314 (-2.8A)
 0.84A 4e3aB-2varA:
36.8		 4e3aB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.72A 4jksA-2varA:
37.0		 4jksA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4jksB-2varA:
36.9		 4jksB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4jkuA-2varA:
36.9		 4jkuA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4jkuB-2varA:
36.9		 4jkuB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k8cA-2varA:
36.9		 4k8cA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k8cB-2varA:
37.0		 4k8cB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.72A 4k8kA-2varA:
36.9		 4k8kA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k8kB-2varA:
36.9		 4k8kB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4k8pA-2varA:
36.9		 4k8pA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4k8pB-2varA:
36.9		 4k8pB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k8tA-2varA:
36.9		 4k8tA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k8tB-2varA:
36.9		 4k8tB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k93A-2varA:
36.9		 4k93A-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4k93B-2varA:
37.0		 4k93B-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k9cA-2varA:
36.9		 4k9cA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.68A 4k9cB-2varA:
36.9		 4k9cB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4k9iA-2varA:
36.9		 4k9iA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4k9iB-2varA:
36.9		 4k9iB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.74A 4kadA-2varA:
37.0		 4kadA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.72A 4kadB-2varA:
36.9		 4kadB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4kahA-2varA:
37.0		 4kahA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4kahB-2varA:
37.0		 4kahB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4kalA-2varA:
36.9		 4kalA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4kalB-2varA:
36.9		 4kalB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4kanA-2varA:
36.9		 4kanA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4kanB-2varA:
36.9		 4kanB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4kbeA-2varA:
36.8		 4kbeA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4kbeB-2varA:
36.9		 4kbeB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4lbgA-2varA:
36.9		 4lbgA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4lbgB-2varA:
37.0		 4lbgB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.72A 4lbxA-2varA:
36.9		 4lbxA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4lbxB-2varA:
37.0		 4lbxB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4lc4A-2varA:
36.9		 4lc4A-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4lc4B-2varA:
36.9		 4lc4B-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.71A 4lcaA-2varA:
37.0		 4lcaA-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 254
ASP A 258
 KDG  A1313 ( 3.3A)
KDF  A1314 ( 4.2A)
None
ANP  A1315 ( 4.6A)
KDF  A1314 (-2.8A)
 0.70A 4lcaB-2varA:
36.9		 4lcaB-2varA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 GLY A 293
ASP A 252
ALA A  33
TYR A  90
LEU A  37
 None
None
KDF  A1314 (-3.4A)
KDF  A1314 ( 4.0A)
None
 1.35A 5hw4B-2varA:
undetectable		 5hw4B-2varA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 2var FRUCTOKINASE
(Sulfolobus
solfataricus) 		5 / 11 ASN A  38
PHE A  39
VAL A 265
THR A 135
ILE A 137
 KDF  A1314 ( 4.2A)
None
None
None
KDG  A1313 ( 3.3A)
 1.30A 6hcoA-2varA:
undetectable
6hcoB-2varA:
undetectable		 6hcoA-2varA:
19.64
6hcoB-2varA:
19.64