SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'KAN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M4D_A_TOYA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		9 / 10 PHE A  32
ASP A  35
ASP A  40
GLU A  82
SER A 117
ALA A 120
ASP A 152
THR A 155
ASP A 179
 COA  A 600 ( 3.7A)
KAN  A 500 (-3.4A)
KAN  A 500 (-3.4A)
KAN  A 500 (-3.8A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.8A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.7A)
KAN  A 500 ( 4.3A)
 0.50A 1m4dA-1m4iA:
35.1		 1m4dA-1m4iA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M4D_A_TOYA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		5 / 10 SER A 117
SER A 119
ALA A 120
ASP A 152
THR A 155
 KAN  A 500 (-3.4A)
COA  A 600 ( 4.0A)
KAN  A 500 ( 4.8A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.7A)
 0.56A 1m4dA-1m4iA:
35.1		 1m4dA-1m4iA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M4D_B_TOYB501_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		8 / 9 ASP A  35
ASP A  40
GLU A  82
SER A 117
ALA A 120
ASP A 152
THR A 155
ASP A 179
 KAN  A 500 (-3.4A)
KAN  A 500 (-3.4A)
KAN  A 500 (-3.8A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.8A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.7A)
KAN  A 500 ( 4.3A)
 0.56A 1m4dB-1m4iA:
33.0		 1m4dB-1m4iA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M4D_B_TOYB501_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		6 / 9 GLU A  82
SER A 117
SER A 119
ALA A 120
ASP A 152
THR A 155
 KAN  A 500 (-3.8A)
KAN  A 500 (-3.4A)
COA  A 600 ( 4.0A)
KAN  A 500 ( 4.8A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.7A)
 0.60A 1m4dB-1m4iA:
33.0		 1m4dB-1m4iA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M4G_A_RIOA500_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		8 / 9 ASP A  35
ASP A  40
GLU A  82
GLY A  83
SER A 117
SER A 119
ASP A 152
ASP A 179
 KAN  A 500 (-3.4A)
KAN  A 500 (-3.4A)
KAN  A 500 (-3.8A)
KAN  A 500 (-3.7A)
KAN  A 500 (-3.4A)
COA  A 600 ( 4.0A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.3A)
 0.69A 1m4gA-1m4iA:
34.5		 1m4gA-1m4iA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M4G_B_RIOB501_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		9 / 9 ASP A  35
ASP A  40
GLU A  82
GLY A  83
SER A 117
SER A 119
ASP A 152
THR A 155
ASP A 179
 KAN  A 500 (-3.4A)
KAN  A 500 (-3.4A)
KAN  A 500 (-3.8A)
KAN  A 500 (-3.7A)
KAN  A 500 (-3.4A)
COA  A 600 ( 4.0A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.7A)
KAN  A 500 ( 4.3A)
 0.70A 1m4gB-1m4iA:
32.7		 1m4gB-1m4iA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M4G_B_RIOB501_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		5 / 9 ASP A  35
SER A 117
SER A 119
ASP A 152
THR A 155
 KAN  A 500 (-3.4A)
KAN  A 500 (-3.4A)
COA  A 600 ( 4.0A)
KAN  A 500 (-3.4A)
KAN  A 500 ( 4.7A)
 1.01A 1m4gB-1m4iA:
32.7		 1m4gB-1m4iA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ND4_A_KANA1300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 10 ARG A 211
ARG A 226
GLU A 230
ASP A 261
GLU A 262
 None
KAN  A   1 (-4.0A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 1.22A 1nd4A-1l8tA:
29.3		 1nd4A-1l8tA:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ND4_A_KANA1300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 10 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.29A 1nd4A-4gkhA:
32.0		 1nd4A-4gkhA:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ND4_A_KANA1300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 10 ASP A 165
ASP A 167
ASP A 198
GLU A 238
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
None
KAN  A 301 (-3.2A)
 1.04A 1nd4A-4gkhA:
32.0		 1nd4A-4gkhA:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ND4_B_KANB2300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 9 ARG A 211
ARG A 226
GLU A 230
ASP A 261
GLU A 262
 None
KAN  A   1 (-4.0A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 1.20A 1nd4B-1l8tA:
29.4		 1nd4B-1l8tA:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ND4_B_KANB2300_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 9 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.28A 1nd4B-4gkhA:
32.1		 1nd4B-4gkhA:
33.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 4qc6 BIFUNCTIONAL AAC/APH
(Staphylococcus
warneri) 		4 / 4 LEU A 174
GLY A  97
ASP A  99
TYR A  86
 None
None
KAN  A 201 ( 3.9A)
None
 1.29A 1oxrA-4qc6A:
undetectable		 1oxrA-4qc6A:
18.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		6 / 12 GLU A  24
MET A  26
ASP A 190
SER A 194
ASP A 261
GLU A 160
 ADP  A 300 (-3.9A)
KAN  A   1 ( 4.0A)
KAN  A   1 (-3.2A)
ADP  A 300 (-3.1A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.2A)
 1.46A 2b0qA-1l8tA:
42.8		 2b0qA-1l8tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 12 GLU A  24
MET A  26
ASP A 208
ASP A 193
SER A 194
 ADP  A 300 (-3.9A)
KAN  A   1 ( 4.0A)
MG  A 302 (-2.1A)
None
ADP  A 300 (-3.1A)
 1.22A 2b0qA-1l8tA:
42.8		 2b0qA-1l8tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		11 / 12 GLU A  24
MET A  26
GLU A 157
GLU A 160
ASP A 190
ASP A 193
SER A 194
ARG A 226
ASP A 231
ASP A 261
GLU A 262
 ADP  A 300 (-3.9A)
KAN  A   1 ( 4.0A)
KAN  A   1 (-3.0A)
KAN  A   1 (-3.2A)
KAN  A   1 (-3.2A)
None
ADP  A 300 (-3.1A)
KAN  A   1 (-4.0A)
KAN  A   1 ( 4.9A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.54A 2b0qA-1l8tA:
42.8		 2b0qA-1l8tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		8 / 12 GLU A  24
MET A  26
GLU A 157
GLU A 160
ASP A 190
GLU A 230
ASP A 231
GLU A 262
 ADP  A 300 (-3.9A)
KAN  A   1 ( 4.0A)
KAN  A   1 (-3.0A)
KAN  A   1 (-3.2A)
KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 ( 4.9A)
KAN  A   1 (-3.1A)
 1.00A 2b0qA-1l8tA:
42.8		 2b0qA-1l8tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 12 GLU A 157
ARG A 226
ASP A 193
ASP A 261
GLU A 262
 KAN  A   1 (-3.0A)
KAN  A   1 (-4.0A)
None
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 1.35A 2b0qA-1l8tA:
42.8		 2b0qA-1l8tA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BUE_A_RIOA1201_0
(AAC(6')-IB)		 4qc6 BIFUNCTIONAL AAC/APH
(Staphylococcus
warneri) 		6 / 11 GLY A  35
TYR A  50
GLN A  74
TYR A  76
ASP A  99
ASP A 136
 FMT  A 203 ( 3.5A)
KAN  A 201 ( 3.9A)
KAN  A 201 (-3.1A)
None
KAN  A 201 ( 3.9A)
KAN  A 201 (-3.8A)
 0.91A 2bueA-4qc6A:
20.0		 2bueA-4qc6A:
28.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 11 LEU A 236
ALA A 106
SER A 200
LEU A 232
ASP A 198
 None
None
KAN  A 301 ( 4.8A)
None
KAN  A 301 (-3.0A)
 1.35A 2c12F-4gkhA:
undetectable		 2c12F-4gkhA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 4qc6 BIFUNCTIONAL AAC/APH
(Staphylococcus
warneri) 		6 / 12 GLY A  35
TYR A  50
GLN A  74
TYR A  76
ASP A  99
ASP A 136
 FMT  A 203 ( 3.5A)
KAN  A 201 ( 3.9A)
KAN  A 201 (-3.1A)
None
KAN  A 201 ( 3.9A)
KAN  A 201 (-3.8A)
 0.87A 2vqyA-4qc6A:
20.1		 2vqyA-4qc6A:
28.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		3 / 3 ARG A  89
GLU A  68
ASP A 198
 None
None
KAN  A 301 (-3.0A)
 0.81A 3g2oA-4gkhA:
undetectable		 3g2oA-4gkhA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 6 ARG A 226
SER A 227
GLY A 189
GLU A  60
 KAN  A   1 (-4.0A)
KAN  A   1 (-4.3A)
None
ADP  A 300 ( 4.8A)
 0.84A 3k9fA-1l8tA:
2.0
3k9fB-1l8tA:
2.0
3k9fD-1l8tA:
undetectable		 3k9fA-1l8tA:
20.09
3k9fB-1l8tA:
20.09
3k9fD-1l8tA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		3 / 3 ASP A 261
GLU A 142
SER A 227
 KAN  A   1 (-3.8A)
None
KAN  A   1 (-4.3A)
 0.79A 3p2kA-1l8tA:
undetectable		 3p2kA-1l8tA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 1m4i AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
(Mycobacterium
tuberculosis) 		5 / 11 VAL A  96
LEU A  99
LEU A 125
VAL A  81
GLY A  83
 COA  A 600 (-3.8A)
None
None
None
KAN  A 500 (-3.7A)
 1.25A 3pghB-1m4iA:
0.0		 3pghB-1m4iA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 LEU A  60
LEU A  92
ASP A 190
ASN A 195
ASP A 208
GLY A 210
 None
None
KAN  A1300 ( 2.8A)
MG  A 400 (-2.7A)
MG  A 400 (-3.2A)
None
 1.29A 4an2A-1nd4A:
7.0		 4an2A-1nd4A:
21.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 12 ASP A 190
ASP A 208
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
MG  A 302 (-2.1A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.94A 4feuA-1l8tA:
28.9
4feuB-1l8tA:
26.6		 4feuA-1l8tA:
31.71
4feuB-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.58A 4feuA-1nd4A:
31.5
4feuB-1nd4A:
30.1		 4feuA-1nd4A:
33.94
4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 12 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.87A 4feuA-1nd4A:
31.5
4feuB-1nd4A:
30.1		 4feuA-1nd4A:
33.94
4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 12 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.44A 4feuA-4gkhA:
40.0
4feuB-4gkhA:
37.7		 4feuA-4gkhA:
100.00
4feuB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 12 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.60A 4feuA-4gkhA:
40.0
4feuB-4gkhA:
37.7		 4feuA-4gkhA:
100.00
4feuB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 12 ASP A 165
ASP A 167
ASP A 198
ASP A 216
ARG A 219
ASN A 234
CYH A 235
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
0J9  A 302 ( 3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.2A)
 0.68A 4feuA-4gkhA:
40.0
4feuB-4gkhA:
37.7		 4feuA-4gkhA:
100.00
4feuB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 12 ASP A 165
ASP A 167
ASP A 198
ASP A 216
ASN A 234
CYH A 235
GLU A 238
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
0J9  A 302 ( 3.7A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.2A)
 0.80A 4feuA-4gkhA:
40.0
4feuB-4gkhA:
37.7		 4feuA-4gkhA:
100.00
4feuB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 12 ASP A 167
ARG A 148
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
None
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.24A 4feuA-4gkhA:
40.0
4feuB-4gkhA:
37.7		 4feuA-4gkhA:
100.00
4feuB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 7 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.85A 4feuB-1l8tA:
26.6		 4feuB-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.27A 4feuB-1nd4A:
30.1		 4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.89A 4feuB-1nd4A:
30.1		 4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 7 ASP A 165
ASP A 167
ASP A 198
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.36A 4feuB-4gkhA:
37.7		 4feuB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 10 ASP A 190
ASP A 208
ARG A 211
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
MG  A 302 (-2.1A)
None
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.50A 4feuC-1l8tA:
28.6		 4feuC-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.64A 4feuC-1nd4A:
31.9		 4feuC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 10 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.46A 4feuC-4gkhA:
38.9		 4feuC-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 10 ASP A 165
ASP A 167
ASP A 198
ASP A 216
ARG A 219
ASN A 234
CYH A 235
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
0J9  A 302 ( 3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.2A)
 0.66A 4feuC-4gkhA:
38.9		 4feuC-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 10 ASP A 167
ARG A 148
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
None
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.37A 4feuC-4gkhA:
38.9		 4feuC-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
ASP A 208
ASP A 261
GLU A 160
 KAN  A   1 (-3.2A)
MG  A 302 (-2.1A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.2A)
 1.05A 4feuD-1l8tA:
26.9		 4feuD-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
ASP A 208
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
MG  A 302 (-2.1A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.38A 4feuD-1l8tA:
26.9		 4feuD-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
ASP A 208
GLU A 230
ASP A 261
 KAN  A   1 (-3.2A)
MG  A 302 (-2.1A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
 0.53A 4feuD-1l8tA:
26.9		 4feuD-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.77A 4feuD-1nd4A:
30.6		 4feuD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 8 ASP A 165
ASP A 167
ASP A 198
ASP A 216
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
0J9  A 302 ( 3.7A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.66A 4feuD-4gkhA:
38.2		 4feuD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		7 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.79A 4feuB-1nd4A:
30.1
4feuE-1nd4A:
32.0		 4feuB-1nd4A:
33.94
4feuE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		9 / 11 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.32A 4feuB-4gkhA:
37.7
4feuE-4gkhA:
40.7		 4feuB-4gkhA:
100.00
4feuE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 11 ASP A 167
ARG A 148
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
None
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.37A 4feuB-4gkhA:
37.7
4feuE-4gkhA:
40.7		 4feuB-4gkhA:
100.00
4feuE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.84A 4feuF-1l8tA:
26.8		 4feuF-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4feuF-1nd4A:
30.4		 4feuF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.83A 4feuF-1nd4A:
30.4		 4feuF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 8 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.12A 4feuF-4gkhA:
38.3		 4feuF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		4 / 8 ASP A 165
ASP A 198
CYH A 235
GLU A 238
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.7A)
None
 1.02A 4feuF-4gkhA:
38.3		 4feuF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		7 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.79A 4fevA-1nd4A:
31.9		 4fevA-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 10 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.35A 4fevA-4gkhA:
39.7		 4fevA-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 7 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.64A 4fevB-1l8tA:
26.9		 4fevB-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 7 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.76A 4fevB-1nd4A:
30.5		 4fevB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 7 ASP A 165
ASP A 167
ASP A 198
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.54A 4fevB-4gkhA:
38.7		 4fevB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		4 / 7 ASP A 165
ASP A 167
ASP A 202
ASN A 234
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
ACT  A 305 (-4.6A)
KAN  A 301 (-3.9A)
 1.23A 4fevB-4gkhA:
38.7		 4fevB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.66A 4fevC-1nd4A:
32.2
4fevD-1nd4A:
31.6
4fevE-1nd4A:
31.1		 4fevC-1nd4A:
33.94
4fevD-1nd4A:
33.94
4fevE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 10 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.53A 4fevC-4gkhA:
41.5
4fevD-4gkhA:
39.6
4fevE-4gkhA:
40.0		 4fevC-4gkhA:
100.00
4fevD-4gkhA:
100.00
4fevE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 7 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.96A 4fevD-1l8tA:
27.6		 4fevD-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4fevD-1nd4A:
31.6		 4fevD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4fevD-1nd4A:
31.6		 4fevD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 7 ASP A 165
ASP A 167
ASP A 198
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.14A 4fevD-4gkhA:
39.6		 4fevD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.28A 4fevE-1nd4A:
31.1		 4fevE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.91A 4fevE-1nd4A:
31.1		 4fevE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 11 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.63A 4fevE-4gkhA:
40.0		 4fevE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 7 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.92A 4fevF-1l8tA:
27.1		 4fevF-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.28A 4fevF-1nd4A:
30.9		 4fevF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.84A 4fevF-1nd4A:
30.9		 4fevF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 7 ASP A 165
ASP A 167
ASP A 198
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.12A 4fevF-4gkhA:
38.8		 4fevF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4fewA-1nd4A:
32.2
4fewD-1nd4A:
31.8		 4fewA-1nd4A:
33.94
4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.97A 4fewA-1nd4A:
32.2
4fewD-1nd4A:
31.8		 4fewA-1nd4A:
33.94
4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 11 ASP A 165
ASP A 167
ASP A 198
GLU A 238
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
None
KAN  A 301 (-3.2A)
 0.78A 4fewA-4gkhA:
41.3
4fewD-4gkhA:
39.4		 4fewA-4gkhA:
100.00
4fewD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		9 / 11 GLN A  35
ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.27A 4fewA-4gkhA:
41.3
4fewD-4gkhA:
39.4		 4fewA-4gkhA:
100.00
4fewD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 7 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.53A 4fewB-1l8tA:
27.5		 4fewB-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4fewB-1nd4A:
31.5		 4fewB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.79A 4fewB-1nd4A:
31.5		 4fewB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 7 ASP A 165
ASP A 167
ASP A 198
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.62A 4fewB-4gkhA:
39.6		 4fewB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.33A 4fewC-1nd4A:
32.2
4fewD-1nd4A:
31.8
4fewF-1nd4A:
31.4		 4fewC-1nd4A:
33.94
4fewD-1nd4A:
33.94
4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		9 / 12 GLN A  35
ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.57A 4fewC-4gkhA:
42.3
4fewD-4gkhA:
39.4
4fewF-4gkhA:
38.8		 4fewC-4gkhA:
100.00
4fewD-4gkhA:
100.00
4fewF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.96A 4fewD-1l8tA:
27.5		 4fewD-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4fewD-1nd4A:
31.8		 4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4fewD-1nd4A:
31.8		 4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 8 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.16A 4fewD-4gkhA:
39.4		 4fewD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4fewE-1nd4A:
31.6
4fewF-1nd4A:
31.4		 4fewE-1nd4A:
33.94
4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.94A 4fewE-1nd4A:
31.6
4fewF-1nd4A:
31.4		 4fewE-1nd4A:
33.94
4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 11 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.15A 4fewE-4gkhA:
40.8
4fewF-4gkhA:
38.8		 4fewE-4gkhA:
100.00
4fewF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 11 ASP A 165
ASP A 167
ASP A 198
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.65A 4fewE-4gkhA:
40.8
4fewF-4gkhA:
38.8		 4fewE-4gkhA:
100.00
4fewF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.95A 4fewF-1l8tA:
27.4		 4fewF-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.25A 4fewF-1nd4A:
31.4		 4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.86A 4fewF-1nd4A:
31.4		 4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 8 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.17A 4fewF-4gkhA:
38.8		 4fewF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.35A 4fexA-1nd4A:
31.7
4fexB-1nd4A:
30.9		 4fexA-1nd4A:
33.94
4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.95A 4fexA-1nd4A:
31.7
4fexB-1nd4A:
30.9		 4fexA-1nd4A:
33.94
4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 9 ASP A 165
ASP A 167
ASP A 198
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.25A 4fexA-4gkhA:
40.3
4fexB-4gkhA:
38.8		 4fexA-4gkhA:
100.00
4fexB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 9 ASP A 165
ASP A 167
ASP A 198
GLU A 238
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
None
KAN  A 301 (-3.2A)
 0.78A 4fexA-4gkhA:
40.3
4fexB-4gkhA:
38.8		 4fexA-4gkhA:
100.00
4fexB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 7 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.87A 4fexB-1l8tA:
27.5		 4fexB-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4fexB-1nd4A:
30.9		 4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.80A 4fexB-1nd4A:
30.9		 4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 7 ASP A 165
ASP A 167
ASP A 198
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.18A 4fexB-4gkhA:
38.8		 4fexB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.32A 4fexA-1nd4A:
31.7
4fexC-1nd4A:
30.8		 4fexA-1nd4A:
33.94
4fexC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.90A 4fexA-1nd4A:
31.7
4fexC-1nd4A:
30.8		 4fexA-1nd4A:
33.94
4fexC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 9 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.19A 4fexA-4gkhA:
40.3
4fexC-4gkhA:
38.6		 4fexA-4gkhA:
100.00
4fexC-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.95A 4fexD-1nd4A:
32.3		 4fexD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.35A 4fexD-1nd4A:
32.3		 4fexD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		10 / 10 ASP A 165
ASP A 167
ASP A 198
ASP A 202
ARG A 219
ASN A 234
CYH A 235
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
ACT  A 305 (-4.6A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.38A 4fexD-4gkhA:
41.4		 4fexD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 10 ASP A 167
ARG A 148
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
None
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.34A 4fexD-4gkhA:
41.4		 4fexD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 9 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.37A 4fexE-1nd4A:
32.1		 4fexE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.93A 4fexE-1nd4A:
32.1		 4fexE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 9 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.28A 4fexE-4gkhA:
40.3		 4fexE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 9 ASP A 165
ASP A 167
ASP A 198
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.71A 4fexE-4gkhA:
40.3		 4fexE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4gkhA-1nd4A:
32.0
4gkhB-1nd4A:
31.3		 4gkhA-1nd4A:
33.94
4gkhB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.95A 4gkhB-1l8tA:
27.6		 4gkhB-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.34A 4gkhB-1nd4A:
31.3		 4gkhB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.70A 4gkhB-1nd4A:
31.3		 4gkhB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkhC-1nd4A:
32.0
4gkhD-1nd4A:
31.4		 4gkhC-1nd4A:
33.94
4gkhD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.97A 4gkhC-1nd4A:
32.0
4gkhD-1nd4A:
31.4		 4gkhC-1nd4A:
33.94
4gkhD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.57A 4gkhD-1l8tA:
19.6		 4gkhD-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.75A 4gkhD-1nd4A:
31.4		 4gkhD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4gkhE-1nd4A:
31.6
4gkhF-1nd4A:
31.3		 4gkhE-1nd4A:
33.94
4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.96A 4gkhF-1l8tA:
27.2		 4gkhF-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		4 / 8 ASP A 157
ASP A 159
ARG A 147
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
None
KAN  A1300 (-3.1A)
 1.16A 4gkhF-1nd4A:
31.5		 4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.51A 4gkhF-1nd4A:
31.5		 4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.86A 4gkhF-1nd4A:
31.5		 4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 7 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.93A 4gkhG-1l8tA:
27.0		 4gkhG-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.28A 4gkhG-1nd4A:
30.6		 4gkhG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4gkhG-1nd4A:
30.6		 4gkhG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkhG-1nd4A:
30.6
4gkhH-1nd4A:
31.7		 4gkhG-1nd4A:
33.94
4gkhH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.92A 4gkhG-1nd4A:
30.6
4gkhH-1nd4A:
31.7		 4gkhG-1nd4A:
33.94
4gkhH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.90A 4gkhI-1nd4A:
31.8
4gkhJ-1nd4A:
31.4		 4gkhI-1nd4A:
33.94
4gkhJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkhI-1nd4A:
31.8
4gkhJ-1nd4A:
31.4		 4gkhI-1nd4A:
33.94
4gkhJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 6 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.34A 4gkhJ-1nd4A:
31.4		 4gkhJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.94A 4gkhC-1l8tA:
28.8
4gkhK-1l8tA:
27.4		 4gkhC-1l8tA:
31.71
4gkhK-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.27A 4gkhC-1nd4A:
32.0
4gkhK-1nd4A:
30.8		 4gkhC-1nd4A:
33.94
4gkhK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.83A 4gkhC-1nd4A:
32.0
4gkhK-1nd4A:
30.8		 4gkhC-1nd4A:
33.94
4gkhK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.32A 4gkhK-1nd4A:
30.8
4gkhL-1nd4A:
31.4		 4gkhK-1nd4A:
33.94
4gkhL-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.96A 4gkhK-1nd4A:
30.8
4gkhL-1nd4A:
31.4		 4gkhK-1nd4A:
33.94
4gkhL-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.98A 4gkiA-1l8tA:
27.6		 4gkiA-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4gkiA-1nd4A:
31.4		 4gkiA-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4gkiA-1nd4A:
31.4		 4gkiA-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 8 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.16A 4gkiA-4gkhA:
39.2		 4gkiA-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4gkiA-1nd4A:
31.6
4gkiB-1nd4A:
31.9		 4gkiA-1nd4A:
33.94
4gkiB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		9 / 11 GLN A  35
ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.12A 4gkiA-4gkhA:
39.2
4gkiB-4gkhA:
42.5		 4gkiA-4gkhA:
100.00
4gkiB-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.96A 4gkiC-1l8tA:
27.1		 4gkiC-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.65A 4gkiC-1nd4A:
31.0		 4gkiC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 8 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.14A 4gkiC-4gkhA:
38.3		 4gkiC-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 8 ASP A 165
ASP A 198
CYH A 235
GLU A 238
ASP A 268
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
 0.98A 4gkiC-4gkhA:
38.3		 4gkiC-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.32A 4gkiC-1nd4A:
31.0
4gkiD-1nd4A:
31.6		 4gkiC-1nd4A:
33.94
4gkiD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.91A 4gkiC-1nd4A:
31.0
4gkiD-1nd4A:
31.6		 4gkiC-1nd4A:
33.94
4gkiD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 11 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.18A 4gkiC-4gkhA:
38.3
4gkiD-4gkhA:
40.8		 4gkiC-4gkhA:
100.00
4gkiD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 11 ASP A 165
ASP A 167
ASP A 198
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.68A 4gkiC-4gkhA:
38.3
4gkiD-4gkhA:
40.8		 4gkiC-4gkhA:
100.00
4gkiD-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		7 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.34A 4gkiE-1nd4A:
31.5		 4gkiE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		9 / 10 GLN A  35
ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.19A 4gkiE-4gkhA:
40.5		 4gkiE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		9 / 10 GLN A  35
ASP A 165
ASP A 198
ARG A 219
ASN A 234
CYH A 235
GLU A 238
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.7A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.88A 4gkiE-4gkhA:
40.5		 4gkiE-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 9 ASP A 190
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
None
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 1.02A 4gkiF-1l8tA:
27.7		 4gkiF-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 9 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.75A 4gkiF-1nd4A:
31.7		 4gkiF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 1.47A 4gkiF-1nd4A:
31.7		 4gkiF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 9 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.57A 4gkiF-4gkhA:
39.8		 4gkiF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 9 ASP A 167
ARG A 148
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
None
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.38A 4gkiF-4gkhA:
39.8		 4gkiF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 9 ASP A 167
ARG A 219
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.17A 4gkiF-4gkhA:
39.8		 4gkiF-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		4 / 8 ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A   1 (-3.2A)
KAN  A   1 (-2.8A)
KAN  A   1 (-3.8A)
KAN  A   1 (-3.1A)
 0.91A 4gkiE-1l8tA:
28.4
4gkiG-1l8tA:
27.1		 4gkiE-1l8tA:
31.71
4gkiG-1l8tA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.26A 4gkiE-1nd4A:
31.5
4gkiG-1nd4A:
31.2		 4gkiE-1nd4A:
33.94
4gkiG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.87A 4gkiE-1nd4A:
31.5
4gkiG-1nd4A:
31.2		 4gkiE-1nd4A:
33.94
4gkiG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 8 ASP A 165
ASP A 167
ASP A 198
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.14A 4gkiE-4gkhA:
40.5
4gkiG-4gkhA:
38.5		 4gkiE-4gkhA:
100.00
4gkiG-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.33A 4gkiG-1nd4A:
31.2
4gkiH-1nd4A:
31.5		 4gkiG-1nd4A:
33.94
4gkiH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.94A 4gkiG-1nd4A:
31.2
4gkiH-1nd4A:
31.5		 4gkiG-1nd4A:
33.94
4gkiH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 10 ASP A 165
ASP A 167
ASP A 198
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.19A 4gkiG-4gkhA:
38.5
4gkiH-4gkhA:
40.8		 4gkiG-4gkhA:
100.00
4gkiH-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 10 ASP A 165
ASP A 167
ASP A 198
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.67A 4gkiG-4gkhA:
38.5
4gkiH-4gkhA:
40.8		 4gkiG-4gkhA:
100.00
4gkiH-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4gkiI-1nd4A:
32.2
4gkiJ-1nd4A:
31.7		 4gkiI-1nd4A:
33.94
4gkiJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		9 / 11 GLN A  35
ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.09A 4gkiI-4gkhA:
43.0
4gkiJ-4gkhA:
39.6		 4gkiI-4gkhA:
100.00
4gkiJ-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 9 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.40A 4gkiJ-1nd4A:
31.7		 4gkiJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4gkiJ-1nd4A:
31.7		 4gkiJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		8 / 9 ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.18A 4gkiJ-4gkhA:
39.6		 4gkiJ-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4gkiK-1nd4A:
31.7		 4gkiK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.91A 4gkiK-1nd4A:
31.7		 4gkiK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 1.48A 4gkiK-1nd4A:
31.7		 4gkiK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		7 / 9 ASP A 165
ASP A 167
ASP A 198
ASN A 234
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.56A 4gkiK-4gkhA:
41.0		 4gkiK-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 9 ASP A 167
ARG A 148
ASN A 234
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
None
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.44A 4gkiK-4gkhA:
41.0		 4gkiK-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		5 / 9 ASP A 167
ARG A 219
GLU A 238
ASP A 268
GLU A 269
 KAN  A 301 (-3.3A)
KAN  A 301 (-3.3A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.26A 4gkiK-4gkhA:
41.0		 4gkiK-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		6 / 9 GLN A  35
ASP A 167
ASP A 198
ASN A 234
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 1.34A 4gkiK-4gkhA:
41.0		 4gkiK-4gkhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.90A 4gkiK-1nd4A:
31.7
4gkiL-1nd4A:
31.9		 4gkiK-1nd4A:
33.94
4gkiL-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkiK-1nd4A:
31.7
4gkiL-1nd4A:
31.9		 4gkiK-1nd4A:
33.94
4gkiL-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		10 / 12 GLN A  35
ASP A 165
ASP A 167
ASP A 198
ARG A 219
ASN A 234
CYH A 235
GLU A 238
ASP A 268
GLU A 269
 None
KAN  A 301 (-3.7A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.0A)
KAN  A 301 (-3.3A)
KAN  A 301 (-3.9A)
KAN  A 301 (-3.7A)
None
KAN  A 301 (-3.8A)
KAN  A 301 (-3.2A)
 0.50A 4gkiK-4gkhA:
41.0
4gkiL-4gkhA:
41.3		 4gkiK-4gkhA:
100.00
4gkiL-4gkhA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 LEU A 241
ASP A 227
ALA A 237
VAL A 113
ILE A 196
 None
KAN  A1300 (-3.8A)
None
None
None
 1.23A 4uuuA-1nd4A:
0.0
4uuuB-1nd4A:
0.0		 4uuuA-1nd4A:
23.81
4uuuB-1nd4A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 LEU A 241
ASP A 227
ALA A 237
VAL A 113
ILE A 196
 None
KAN  A1300 (-3.8A)
None
None
None
 1.23A 4uuuB-1nd4A:
undetectable		 4uuuB-1nd4A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		4 / 6 SER A 200
LEU A 201
ASP A 202
LEU A 232
 KAN  A 301 ( 4.8A)
None
ACT  A 305 (-4.6A)
None
 1.02A 4wozA-4gkhA:
undetectable
4wozB-4gkhA:
undetectable		 4wozA-4gkhA:
20.38
4wozB-4gkhA:
20.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XJE_A_TOYA202_1
(AADB)		 4wql 2''-AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE
(Klebsiella
pneumoniae) 		8 / 8 ASP A  44
ASP A  46
TYR A  74
ASP A  86
GLU A  88
ILE A  99
ASP A 131
TYR A 134
 MG  A 202 (-2.5A)
MG  A 201 (-2.4A)
KAN  A 203 (-3.8A)
KAN  A 203 ( 3.2A)
KAN  A 203 ( 2.6A)
GOL  A 213 ( 4.3A)
KAN  A 203 ( 2.7A)
KAN  A 203 (-3.8A)
 0.48A 4xjeA-4wqlA:
31.9		 4xjeA-4wqlA:
95.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 4wql 2''-AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE
(Klebsiella
pneumoniae) 		8 / 8 ASP A  44
ASP A  46
TYR A  74
ASP A  86
GLU A  88
ILE A  99
ASP A 131
TYR A 134
 MG  A 202 (-2.5A)
MG  A 201 (-2.4A)
KAN  A 203 (-3.8A)
KAN  A 203 ( 3.2A)
KAN  A 203 ( 2.6A)
GOL  A 213 ( 4.3A)
KAN  A 203 ( 2.7A)
KAN  A 203 (-3.8A)
 0.17A 5cfsA-4wqlA:
33.1		 5cfsA-4wqlA:
95.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CFT_A_51GA204_1
(AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE (2')-IA)		 4wql 2''-AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE
(Klebsiella
pneumoniae) 		9 / 9 ASP A  44
ASP A  46
TYR A  74
LEU A  77
ASP A  86
GLU A  88
ILE A  99
ASP A 131
TYR A 134
 MG  A 202 (-2.5A)
MG  A 201 (-2.4A)
KAN  A 203 (-3.8A)
None
KAN  A 203 ( 3.2A)
KAN  A 203 ( 2.6A)
GOL  A 213 ( 4.3A)
KAN  A 203 ( 2.7A)
KAN  A 203 (-3.8A)
 0.27A 5cftA-4wqlA:
32.8		 5cftA-4wqlA:
95.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 4qc6 BIFUNCTIONAL AAC/APH
(Staphylococcus
warneri) 		5 / 12 LEU A 135
VAL A 133
TYR A  34
TYR A  50
GLY A  73
 None
None
KAN  A 201 ( 3.6A)
KAN  A 201 ( 3.9A)
None
 1.42A 5i8fA-4qc6A:
undetectable		 5i8fA-4qc6A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 4qc6 BIFUNCTIONAL AAC/APH
(Staphylococcus
warneri) 		3 / 3 TYR A  34
TYR A  76
GLN A  74
 KAN  A 201 ( 3.6A)
None
KAN  A 201 (-3.1A)
 0.92A 5jsdA-4qc6A:
undetectable
5jsdB-4qc6A:
undetectable		 5jsdA-4qc6A:
12.33
5jsdB-4qc6A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 4qc6 BIFUNCTIONAL AAC/APH
(Staphylococcus
warneri) 		3 / 3 TYR A  34
TYR A  76
GLN A  74
 KAN  A 201 ( 3.6A)
None
KAN  A 201 (-3.1A)
 0.92A 5jsdB-4qc6A:
undetectable
5jsdC-4qc6A:
undetectable		 5jsdB-4qc6A:
12.33
5jsdC-4qc6A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB
(Acinetobacter
baumannii) 		4 / 6 LEU A 232
SER A 200
PHE A 199
ASP A 198
 None
KAN  A 301 ( 4.8A)
None
KAN  A 301 (-3.0A)
 1.22A 5om3A-4gkhA:
undetectable
5om3B-4gkhA:
undetectable		 5om3A-4gkhA:
16.41
5om3B-4gkhA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Enterococcus
faecalis) 		5 / 12 GLY A 192
LEU A 240
VAL A 238
ILE A 228
ASP A 231
 None
None
None
None
KAN  A   1 ( 4.9A)
 1.06A 6bxmA-1l8tA:
undetectable		 6bxmA-1l8tA:
21.02