SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'JOZ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMO_E_ADNE351_1
(CAMP-DEPENDENT
PROTEIN KINASE)		 3nuu PKB-LIKE
(Homo
sapiens) 		10 / 12 LEU A  88
GLY A  89
VAL A  96
ALA A 109
VAL A 143
GLU A 166
ASN A 210
LEU A 212
THR A 222
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
None
JOZ  A 361 (-3.7A)
SO4  A   5 ( 4.5A)
 0.88A 1fmoE-3nuuA:
35.1		 1fmoE-3nuuA:
36.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.59A 1iepA-3nuuA:
22.8		 1iepA-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
 0.53A 1iepB-3nuuA:
23.0		 1iepB-3nuuA:
25.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 9 LEU A  88
GLY A  89
VAL A  96
ALA A 109
TYR A 161
ALA A 162
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
JOZ  A 361 (-3.8A)
None
 0.61A 1muoA-3nuuA:
10.9		 1muoA-3nuuA:
33.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
 0.57A 1opjA-3nuuA:
22.5		 1opjA-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
ASP A 223
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
SO4  A   5 ( 4.5A)
 0.85A 1opjB-3nuuA:
22.5		 1opjB-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_1
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
SO4  A   5 ( 4.5A)
 0.78A 1t46A-3nuuA:
23.1		 1t46A-3nuuA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 9 LEU A  88
VAL A  96
ALA A 109
ALA A 162
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
JOZ  A 361 (-3.8A)
None
None
 0.71A 1xbbA-3nuuA:
25.4		 1xbbA-3nuuA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLY A 165
LEU A 168
ARG A 172
LEU A 212
THR A 222
 JOZ  A 361 (-3.4A)
None
None
None
None
JOZ  A 361 (-3.7A)
 0.70A 1xkkA-3nuuA:
22.3		 1xkkA-3nuuA:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLY A 165
LEU A 168
LEU A 212
THR A 222
PHE A 224
 JOZ  A 361 (-3.4A)
None
None
None
JOZ  A 361 (-3.7A)
None
 0.96A 1xkkA-3nuuA:
22.3		 1xkkA-3nuuA:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 GLY A 165
LEU A 168
ARG A 172
LEU A 212
THR A 222
ASP A 223
 None
None
None
None
JOZ  A 361 (-3.7A)
SO4  A   5 ( 4.5A)
 0.80A 1xkkA-3nuuA:
22.3		 1xkkA-3nuuA:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 GLY A 165
LEU A 168
LEU A 212
THR A 222
ASP A 223
PHE A 224
 None
None
None
JOZ  A 361 (-3.7A)
SO4  A   5 ( 4.5A)
None
 1.04A 1xkkA-3nuuA:
22.3		 1xkkA-3nuuA:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 11 GLY A  89
GLY A  91
VAL A  96
ALA A 109
TYR A 161
ALA A 162
LEU A 212
 JOZ  A 361 ( 4.3A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
JOZ  A 361 (-3.8A)
None
 0.72A 2evaA-3nuuA:
24.5		 2evaA-3nuuA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
GLY A  89
VAL A  96
ALA A 109
ASP A 205
LYS A 207
ASN A 210
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
 0.78A 2fumA-3nuuA:
8.8		 2fumA-3nuuA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
GLY A  89
VAL A  96
ALA A 109
TYR A 161
LYS A 207
ASN A 210
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
 0.65A 2fumB-3nuuA:
28.3		 2fumB-3nuuA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
GLY A  89
VAL A  96
ALA A 109
TYR A 161
ASN A 210
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
 0.61A 2fumC-3nuuA:
26.4		 2fumC-3nuuA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
GLY A  89
GLY A  91
VAL A  96
ALA A 109
LYS A 207
ASN A 210
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
 0.76A 2fumD-3nuuA:
26.5		 2fumD-3nuuA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
ASP A 223
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
SO4  A   5 ( 4.5A)
 0.83A 2hyyA-3nuuA:
23.1		 2hyyA-3nuuA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.53A 2hyyA-3nuuA:
23.1		 2hyyA-3nuuA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.54A 2hyyB-3nuuA:
23.1		 2hyyB-3nuuA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		4 / 6 LEU A  88
LYS A 111
VAL A 133
MET A 134
 JOZ  A 361 (-4.1A)
SO4  A   5 (-2.8A)
None
None
 0.87A 2hyyC-3nuuA:
23.3		 2hyyC-3nuuA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
GLY A  89
VAL A  96
LYS A 111
TYR A 161
ALA A 162
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
SO4  A   5 (-2.8A)
None
JOZ  A 361 (-3.8A)
None
 0.69A 2ivuA-3nuuA:
26.9		 2ivuA-3nuuA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 GLY A  89
VAL A  96
ALA A 109
LEU A 159
TYR A 161
GLY A 165
ASP A 223
 JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
JOZ  A 361 (-4.0A)
None
None
SO4  A   5 ( 4.5A)
 0.64A 2wgjA-3nuuA:
23.7		 2wgjA-3nuuA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 9 LEU A  88
VAL A  96
ALA A 109
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
SO4  A   5 ( 4.5A)
 0.74A 2xp2A-3nuuA:
6.4		 2xp2A-3nuuA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 9 LEU A  88
VAL A  96
ALA A 109
LEU A 159
GLY A 165
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
JOZ  A 361 (-4.0A)
None
SO4  A   5 ( 4.5A)
 0.79A 2xp2A-3nuuA:
6.4		 2xp2A-3nuuA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 ALA A 109
LYS A 111
GLU A 130
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.77A 2y6oA-3nuuA:
23.8		 2y6oA-3nuuA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOX_A_EMHA901_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 10 LEU A  88
ALA A 109
LYS A 111
LEU A 159
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
JOZ  A 361 (-4.0A)
None
None
 0.81A 3aoxA-3nuuA:
23.2		 3aoxA-3nuuA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C7Q_A_XINA1172_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
GLY A  89
ALA A 109
LYS A 111
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
 0.59A 3c7qA-3nuuA:
22.7		 3c7qA-3nuuA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
MET A 134
GLY A 165
HIS A 203
LEU A 212
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.62A 3cs9A-3nuuA:
22.7		 3cs9A-3nuuA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
VAL A 133
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.77A 3cs9A-3nuuA:
22.7		 3cs9A-3nuuA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
VAL A 133
MET A 134
GLY A 165
HIS A 203
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.75A 3cs9B-3nuuA:
22.9		 3cs9B-3nuuA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
VAL A 133
MET A 134
HIS A 203
ASP A 223
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
SO4  A   5 ( 4.5A)
 1.05A 3cs9C-3nuuA:
22.6		 3cs9C-3nuuA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 12 ALA A 109
GLU A 130
MET A 134
GLY A 165
HIS A 203
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.59A 3cs9D-3nuuA:
21.7		 3cs9D-3nuuA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUP_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
GLY A  89
GLY A  91
VAL A  96
ALA A 109
LYS A 111
TYR A 161
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
 0.78A 3fupA-3nuuA:
25.2		 3fupA-3nuuA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0E_A_B49A9000_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 11 LEU A  88
VAL A  96
ALA A 109
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
 0.29A 3g0eA-3nuuA:
21.9		 3g0eA-3nuuA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0F_A_B49A9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 11 LEU A  88
VAL A  96
ALA A 109
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
 0.37A 3g0fA-3nuuA:
23.2		 3g0fA-3nuuA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0F_B_B49B9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 10 LEU A  88
VAL A  96
ALA A 109
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
 0.42A 3g0fB-3nuuA:
23.3		 3g0fB-3nuuA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G5D_B_1N1B1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
None
 0.80A 3g5dB-3nuuA:
24.3		 3g5dB-3nuuA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
 0.60A 3gvuA-3nuuA:
23.1		 3gvuA-3nuuA:
27.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 12 ALA A 109
GLU A 130
MET A 134
HIS A 203
LEU A 212
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.56A 3ik3A-3nuuA:
23.1		 3ik3A-3nuuA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 12 ALA A 109
GLU A 130
MET A 134
HIS A 203
LEU A 212
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.57A 3ik3B-3nuuA:
22.8		 3ik3B-3nuuA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
ALA A 109
LYS A 111
GLU A 130
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.79A 3k54A-3nuuA:
23.5		 3k54A-3nuuA:
28.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.55A 3k5vA-3nuuA:
22.5		 3k5vA-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.56A 3k5vB-3nuuA:
22.3		 3k5vB-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
GLY A  89
GLY A  91
VAL A  96
ALA A 109
LYS A 111
TYR A 161
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
 0.63A 3lxnA-3nuuA:
25.4		 3lxnA-3nuuA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
 0.64A 3ms9A-3nuuA:
22.5		 3ms9A-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.58A 3ms9B-3nuuA:
22.6		 3ms9B-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
 0.62A 3mssA-3nuuA:
22.7		 3mssA-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.59A 3mssB-3nuuA:
22.6		 3mssB-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
 0.63A 3mssC-3nuuA:
22.6		 3mssC-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.60A 3mssD-3nuuA:
22.6		 3mssD-3nuuA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
None
 0.67A 3octA-3nuuA:
8.5		 3octA-3nuuA:
27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 VAL A  96
ALA A 109
GLU A 130
VAL A 133
MET A 134
TYR A 161
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.87A 3oezB-3nuuA:
23.1		 3oezB-3nuuA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
 0.70A 3pyyA-3nuuA:
22.6		 3pyyA-3nuuA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.63A 3pyyA-3nuuA:
22.6		 3pyyA-3nuuA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
VAL A 143
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.76A 3pyyB-3nuuA:
22.6		 3pyyB-3nuuA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 VAL A  96
ALA A 109
GLU A 130
TYR A 161
ALA A 162
LEU A 196
HIS A 203
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
JOZ  A 361 (-3.8A)
None
None
 0.80A 3rgfA-3nuuA:
23.7		 3rgfA-3nuuA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
None
 0.66A 3sxrA-3nuuA:
25.1		 3sxrA-3nuuA:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
None
 0.60A 3sxrB-3nuuA:
24.6		 3sxrB-3nuuA:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UE4_B_DB8B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.70A 3ue4B-3nuuA:
25.0		 3ue4B-3nuuA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
GLY A 165
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
 0.51A 3wzdA-3nuuA:
23.1		 3wzdA-3nuuA:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
GLY A 165
LEU A 196
HIS A 203
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
None
 0.62A 3wzeA-3nuuA:
23.2		 3wzeA-3nuuA:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
ALA A 109
LYS A 111
GLU A 130
HIS A 203
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
SO4  A   5 ( 4.5A)
 0.81A 3zosA-3nuuA:
22.7		 3zosA-3nuuA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
ALA A 109
LYS A 111
GLU A 130
LEU A 196
HIS A 203
ARG A 204
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
SEP  A 241 ( 3.4A)
None
 0.81A 3zosA-3nuuA:
22.7		 3zosA-3nuuA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 9 LEU A  88
MET A 134
LEU A 137
TYR A 161
ILE A 221
 JOZ  A 361 (-4.1A)
None
None
None
None
 0.80A 3zosB-3nuuA:
22.8		 3zosB-3nuuA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
 0.49A 4ag8A-3nuuA:
23.2		 4ag8A-3nuuA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
VAL A 143
GLY A 165
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
 0.60A 4ag8A-3nuuA:
23.2		 4ag8A-3nuuA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGC_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
 0.51A 4agcA-3nuuA:
22.6		 4agcA-3nuuA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 9 LEU A  88
VAL A  96
ALA A 109
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
SO4  A   5 ( 4.5A)
 0.76A 4anqA-3nuuA:
23.6		 4anqA-3nuuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
GLY A 165
LEU A 196
HIS A 203
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
None
 0.66A 4asdA-3nuuA:
22.9		 4asdA-3nuuA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
MET A 134
TYR A 161
ASP A 223
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
SO4  A   5 ( 4.5A)
 0.86A 4bkjA-3nuuA:
22.8		 4bkjA-3nuuA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CKI_A_ADNA2022_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 11 LEU A  88
GLY A  89
GLY A  91
VAL A  96
ALA A 109
TYR A 161
ALA A 162
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
JOZ  A 361 (-3.8A)
None
 0.81A 4ckiA-3nuuA:
26.8		 4ckiA-3nuuA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CKI_A_ADNA2022_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 11 LEU A  88
GLY A  89
VAL A  96
ALA A 109
TYR A 161
ALA A 162
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
JOZ  A 361 (-3.8A)
None
None
 0.74A 4ckiA-3nuuA:
26.8		 4ckiA-3nuuA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CKJ_A_ADNA2014_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
GLY A  89
VAL A  96
ALA A 109
TYR A 161
ALA A 162
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
JOZ  A 361 (-3.8A)
None
 0.59A 4ckjA-3nuuA:
26.8		 4ckjA-3nuuA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HJO_A_AQ4A1001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLY A 165
LEU A 212
THR A 222
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
JOZ  A 361 (-3.7A)
 0.83A 4hjoA-3nuuA:
22.8		 4hjoA-3nuuA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I22_A_IREA9001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
GLY A  89
VAL A  96
ALA A 109
LYS A 111
GLY A 165
LEU A 212
THR A 222
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
JOZ  A 361 (-3.7A)
 0.87A 4i22A-3nuuA:
22.3		 4i22A-3nuuA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAA_A_RTZA401_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 11 VAL A  96
ALA A 109
LYS A 111
LEU A 159
LEU A 212
ASP A 223
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
JOZ  A 361 (-4.0A)
None
SO4  A   5 ( 4.5A)
 0.80A 4iaaA-3nuuA:
28.9		 4iaaA-3nuuA:
26.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 GLY A  89
VAL A  96
ALA A 109
LEU A 145
GLY A 165
GLU A 166
LEU A 212
 JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
None
 0.68A 4ifgA-3nuuA:
25.0		 4ifgA-3nuuA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 GLY A  89
VAL A  96
ALA A 109
LYS A 111
LEU A 145
GLY A 165
LEU A 212
 JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
 0.79A 4ifgA-3nuuA:
25.0		 4ifgA-3nuuA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MKC_A_4MKA1503_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		9 / 12 LEU A  88
GLY A  91
VAL A  96
ALA A 109
LYS A 111
LEU A 159
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
JOZ  A 361 (-4.0A)
None
None
SO4  A   5 ( 4.5A)
 0.77A 4mkcA-3nuuA:
24.2		 4mkcA-3nuuA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
TYR A 161
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
SO4  A   5 ( 4.5A)
 0.96A 4mxyB-3nuuA:
25.2		 4mxyB-3nuuA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
TYR A 161
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
SO4  A   5 ( 4.5A)
 0.96A 4mxzB-3nuuA:
25.2		 4mxzB-3nuuA:
25.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0S_A_ADNA500_1
(AURORA KINASE A)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 11 LEU A  88
GLY A  89
VAL A  96
ALA A 109
LYS A 111
ASN A 210
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
 0.54A 4o0sA-3nuuA:
33.5		 4o0sA-3nuuA:
35.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3nuu PKB-LIKE
(Homo
sapiens) 		4 / 6 VAL A  96
ALA A 109
LYS A 111
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
 0.59A 4o0uA-3nuuA:
25.2		 4o0uA-3nuuA:
34.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 6 LEU A  88
GLY A  89
VAL A  96
ALA A 109
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
 0.34A 4o0wA-3nuuA:
26.4		 4o0wA-3nuuA:
34.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 11 ALA A 109
LYS A 111
GLU A 130
TYR A 161
LEU A 212
ASP A 223
 JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
SO4  A   5 ( 4.5A)
 0.82A 4qmsA-3nuuA:
21.5		 4qmsA-3nuuA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 12 ALA A 109
GLU A 130
MET A 134
ARG A 204
ASP A 223
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
SEP  A 241 ( 3.4A)
SO4  A   5 ( 4.5A)
 1.13A 4qrcA-3nuuA:
24.1		 4qrcA-3nuuA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 12 ALA A 109
GLU A 130
MET A 134
LEU A 196
ARG A 204
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
SEP  A 241 ( 3.4A)
 0.80A 4qrcA-3nuuA:
24.1		 4qrcA-3nuuA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 VAL A  96
ALA A 109
LYS A 111
GLU A 130
MET A 134
LEU A 212
ASP A 223
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
SO4  A   5 ( 4.5A)
 0.63A 4r7iA-3nuuA:
22.9		 4r7iA-3nuuA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLY A 165
ASN A 210
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
SO4  A   5 ( 4.5A)
 0.61A 4twpA-3nuuA:
24.9		 4twpA-3nuuA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 ALA A 109
GLU A 130
MET A 134
ALA A 162
HIS A 203
LEU A 212
ASP A 223
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
JOZ  A 361 (-3.8A)
None
None
SO4  A   5 ( 4.5A)
 0.95A 4tyjA-3nuuA:
23.6		 4tyjA-3nuuA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 10 LEU A  88
VAL A  96
GLU A 130
VAL A 143
TYR A 161
ILE A 221
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
SO4  A   5 (-3.1A)
None
None
None
 0.55A 4u0iA-3nuuA:
23.1		 4u0iA-3nuuA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 10 LEU A  88
VAL A  96
VAL A 143
TYR A 161
ARG A 204
ILE A 221
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
None
None
SEP  A 241 ( 3.4A)
None
 0.81A 4u0iA-3nuuA:
23.1		 4u0iA-3nuuA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3nuu PKB-LIKE
(Homo
sapiens) 		9 / 11 LEU A  88
GLY A  91
VAL A  96
ALA A 109
TYR A 161
GLY A 165
ASN A 210
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
None
SO4  A   5 ( 4.5A)
 0.77A 4u5jA-3nuuA:
26.2		 4u5jA-3nuuA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 9 LEU A  88
VAL A  96
ALA A 109
TYR A 161
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
SO4  A   5 ( 4.5A)
 0.87A 4u5jB-3nuuA:
25.4		 4u5jB-3nuuA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 7 VAL A  96
MET A 134
ALA A 162
ARG A 204
ILE A 221
 JOZ  A 361 ( 4.7A)
None
JOZ  A 361 (-3.8A)
SEP  A 241 ( 3.4A)
None
 1.03A 4uxqA-3nuuA:
23.8		 4uxqA-3nuuA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
MET A 134
ALA A 162
HIS A 203
ASP A 223
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
JOZ  A 361 (-3.8A)
None
SO4  A   5 ( 4.5A)
 0.94A 4v01A-3nuuA:
22.9		 4v01A-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
MET A 134
ALA A 162
LEU A 196
HIS A 203
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
JOZ  A 361 (-3.8A)
None
None
 0.74A 4v01A-3nuuA:
22.9		 4v01A-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 9 LEU A  88
VAL A  96
TYR A 161
ARG A 204
LEU A 212
ILE A 221
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
None
SEP  A 241 ( 3.4A)
None
None
 0.78A 4v01A-3nuuA:
22.9		 4v01A-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
MET A 134
ALA A 162
HIS A 203
ASP A 223
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
JOZ  A 361 (-3.8A)
None
SO4  A   5 ( 4.5A)
 0.89A 4v01B-3nuuA:
23.3		 4v01B-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
MET A 134
ALA A 162
LEU A 196
HIS A 203
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
JOZ  A 361 (-3.8A)
None
None
 0.70A 4v01B-3nuuA:
23.3		 4v01B-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 9 LEU A  88
VAL A  96
LYS A 111
TYR A 161
ARG A 204
LEU A 212
ILE A 221
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
SO4  A   5 (-2.8A)
None
SEP  A 241 ( 3.4A)
None
None
 0.82A 4v01B-3nuuA:
23.3		 4v01B-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
ALA A 162
HIS A 203
ASP A 223
GLY A 225
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
JOZ  A 361 (-3.8A)
None
SO4  A   5 ( 4.5A)
SO4  A   5 ( 4.6A)
 1.35A 4v04A-3nuuA:
22.9		 4v04A-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
ALA A 162
HIS A 203
GLY A 225
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
JOZ  A 361 (-3.8A)
None
SO4  A   5 ( 4.6A)
 1.17A 4v04A-3nuuA:
22.9		 4v04A-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
GLU A 130
ALA A 162
LEU A 196
HIS A 203
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
JOZ  A 361 (-3.8A)
None
None
 0.71A 4v04A-3nuuA:
22.9		 4v04A-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
VAL A  96
LYS A 111
TYR A 161
ARG A 204
LEU A 212
ILE A 221
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
SO4  A   5 (-2.8A)
None
SEP  A 241 ( 3.4A)
None
None
 1.05A 4v04B-3nuuA:
23.4		 4v04B-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
VAL A  96
MET A 134
TYR A 161
ARG A 204
LEU A 212
ILE A 221
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
None
None
SEP  A 241 ( 3.4A)
None
None
 0.93A 4v04B-3nuuA:
23.4		 4v04B-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
GLU A 130
ALA A 162
HIS A 203
ASP A 223
GLY A 225
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
JOZ  A 361 (-3.8A)
None
SO4  A   5 ( 4.5A)
SO4  A   5 ( 4.6A)
 1.31A 4v04B-3nuuA:
23.4		 4v04B-3nuuA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WKQ_A_IREA1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
ALA A 109
LYS A 111
GLU A 130
MET A 134
GLY A 165
LEU A 212
THR A 222
 JOZ  A 361 (-4.1A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
None
JOZ  A 361 (-3.7A)
 0.78A 4wkqA-3nuuA:
24.5		 4wkqA-3nuuA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
MET A 134
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
 0.81A 4xeyA-3nuuA:
24.7		 4xeyA-3nuuA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 9 LEU A  88
VAL A  96
ALA A 109
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
SO4  A   5 ( 4.5A)
 0.75A 5aaaA-3nuuA:
24.0		 5aaaA-3nuuA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 9 LEU A  88
VAL A  96
ALA A 109
LEU A 159
GLY A 165
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
JOZ  A 361 (-4.0A)
None
SO4  A   5 ( 4.5A)
 0.81A 5aaaA-3nuuA:
24.0		 5aaaA-3nuuA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
SO4  A   5 ( 4.5A)
 0.87A 5aabA-3nuuA:
23.6		 5aabA-3nuuA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
VAL A  96
ALA A 109
LYS A 111
LEU A 159
GLY A 165
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
JOZ  A 361 (-4.0A)
None
SO4  A   5 ( 4.5A)
 0.94A 5aabA-3nuuA:
23.6		 5aabA-3nuuA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAC_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLY A 165
LEU A 212
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
SO4  A   5 ( 4.5A)
 0.94A 5aacA-3nuuA:
23.5		 5aacA-3nuuA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAC_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
VAL A  96
ALA A 109
LYS A 111
LEU A 159
GLY A 165
ASP A 223
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
JOZ  A 361 (-4.0A)
None
SO4  A   5 ( 4.5A)
 0.99A 5aacA-3nuuA:
23.5		 5aacA-3nuuA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		9 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.62A 5bvwA-3nuuA:
23.0		 5bvwA-3nuuA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 VAL A  96
ALA A 109
LYS A 111
TYR A 161
ALA A 162
PHE A 224
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
JOZ  A 361 (-3.8A)
None
 0.90A 5hesB-3nuuA:
22.7		 5hesB-3nuuA:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 ALA A 109
LYS A 111
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
None
None
None
None
 0.71A 5i9yA-3nuuA:
23.7		 5i9yA-3nuuA:
24.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 7 GLY A  89
GLY A  91
SER A  92
LEU A 113
GLU A 166
 JOZ  A 361 ( 4.3A)
SO4  A   5 ( 4.4A)
SO4  A   5 (-4.4A)
None
None
 1.34A 5izfA-3nuuA:
28.9		 5izfA-3nuuA:
37.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3nuu PKB-LIKE
(Homo
sapiens) 		5 / 7 GLY A  89
SER A  92
LYS A 111
LEU A 113
GLU A 166
 JOZ  A 361 ( 4.3A)
SO4  A   5 (-4.4A)
SO4  A   5 (-2.8A)
None
None
 1.30A 5izfA-3nuuA:
28.9		 5izfA-3nuuA:
37.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LVN_A_ADNA402_1
(3-PHOSPHOINOSITIDE-D
EPENDENT PROTEIN
KINASE 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		9 / 11 LEU A  88
GLY A  89
VAL A  96
ALA A 109
LEU A 159
TYR A 161
ALA A 162
GLU A 166
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
JOZ  A 361 (-4.0A)
None
JOZ  A 361 (-3.8A)
None
None
 0.34A 5lvnA-3nuuA:
43.5		 5lvnA-3nuuA:
99.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 3nuu PKB-LIKE
(Homo
sapiens) 		9 / 12 GLY A  89
VAL A  96
ALA A 109
LYS A 111
GLU A 130
LEU A 159
TYR A 161
GLY A 165
GLU A 166
 JOZ  A 361 ( 4.3A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
JOZ  A 361 (-4.0A)
None
None
None
 0.75A 5mafA-3nuuA:
31.7		 5mafA-3nuuA:
15.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 10 LEU A  88
VAL A  96
ALA A 109
VAL A 143
TYR A 161
LEU A 212
THR A 222
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
JOZ  A 361 (-3.7A)
 0.68A 5n3hA-3nuuA:
35.0		 5n3hA-3nuuA:
34.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OWR_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3nuu PKB-LIKE
(Homo
sapiens) 		4 / 8 ALA A 109
GLU A 130
LEU A 212
ASP A 223
 JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
SO4  A   5 ( 4.5A)
 0.71A 5owrA-3nuuA:
23.7		 5owrA-3nuuA:
28.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  98
ALA A 109
GLU A 130
MET A 134
GLY A 165
LEU A 212
 None
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.38A 5te0A-3nuuA:
26.3		 5te0A-3nuuA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		6 / 12 LEU A  98
ALA A 109
GLU A 130
VAL A 143
GLY A 165
LEU A 212
 None
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
None
 0.61A 5te0A-3nuuA:
26.3		 5te0A-3nuuA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
 0.76A 5y7zA-3nuuA:
26.8		 5y7zA-3nuuA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
GLY A 165
LEU A 212
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
 0.76A 5y7zA-3nuuA:
26.8		 5y7zA-3nuuA:
28.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
TYR A 161
ALA A 162
GLY A 165
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
None
JOZ  A 361 (-3.8A)
None
 0.56A 5zv2A-3nuuA:
23.1		 5zv2A-3nuuA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
GLU A 130
MET A 134
ALA A 162
GLY A 165
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-3.1A)
None
JOZ  A 361 (-3.8A)
None
 0.57A 5zv2B-3nuuA:
23.2		 5zv2B-3nuuA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		7 / 12 LEU A  88
VAL A  96
ALA A 109
LYS A 111
GLU A 130
ALA A 162
GLY A 165
 JOZ  A 361 (-4.1A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
JOZ  A 361 (-3.8A)
None
 0.46A 5zv2B-3nuuA:
23.2		 5zv2B-3nuuA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nuu PKB-LIKE
(Homo
sapiens) 		8 / 12 VAL A  96
ALA A 109
LYS A 111
GLU A 130
MET A 134
TYR A 161
GLY A 165
LEU A 212
 JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
SO4  A   5 (-2.8A)
SO4  A   5 (-3.1A)
None
None
None
None
 0.70A 6bsdA-3nuuA:
22.8		 6bsdA-3nuuA:
14.60