SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'JLS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4wo4 ANTIGEN-PRESENTING
GLYCOPROTEIN CD1D
(Homo
sapiens) 		4 / 6 PHE A 114
TYR A  73
ARG A  74
THR A  78
 JLS  A 310 (-4.8A)
JLS  A 310 (-3.9A)
None
None
 0.95A 5b1aN-4wo4A:
undetectable
5b1aW-4wo4A:
undetectable		 5b1aN-4wo4A:
19.41
5b1aW-4wo4A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 4wo4 ANTIGEN-PRESENTING
GLYCOPROTEIN CD1D
(Homo
sapiens) 		5 / 11 LEU A 124
PHE A  84
ILE A 145
ASN A 142
VAL A 147
 None
JLS  A 310 ( 4.5A)
None
None
None
 1.37A 5hjiA-4wo4A:
undetectable		 5hjiA-4wo4A:
18.75