SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'JLN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  14
VAL A 108
VAL A  78
HIS A  79
LEU A  74
 None
None
None
None
JLN  A1528 (-4.1A)
 1.07A 1db1A-4a1oA:
undetectable		 1db1A-4a1oA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH
(Mycobacterium
tuberculosis) 		5 / 10 THR A  73
VAL A  57
ASN A 109
VAL A 108
GLY A 134
 JLN  A1528 (-2.7A)
None
None
None
JLN  A1528 (-3.2A)
 1.42A 2x2iD-4a1oA:
1.7		 2x2iD-4a1oA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH
(Mycobacterium
tuberculosis) 		4 / 5 VAL A 108
VAL A  17
THR A  73
THR A 152
 None
None
JLN  A1528 (-2.7A)
None
 1.27A 3bjwD-4a1oA:
undetectable		 3bjwD-4a1oA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH
(Mycobacterium
tuberculosis) 		5 / 9 LEU A  82
PHE A 103
ILE A  38
THR A  40
THR A  73
 None
None
None
JLN  A1528 (-4.0A)
JLN  A1528 (-2.7A)
 1.31A 3mdtA-4a1oA:
undetectable		 3mdtA-4a1oA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH
(Mycobacterium
tuberculosis) 		6 / 10 LEU A  82
PHE A 103
VAL A 106
ILE A  38
THR A  40
THR A  73
 None
None
None
None
JLN  A1528 (-4.0A)
JLN  A1528 (-2.7A)
 1.17A 4j14A-4a1oA:
1.2		 4j14A-4a1oA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  82
THR A  73
GLY A  81
PHE A 103
LEU A  14
 None
JLN  A1528 (-2.7A)
None
None
None
 1.33A 5jo9A-4a1oA:
4.4		 5jo9A-4a1oA:
19.59