SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'JAF'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O01_B_PQNB5002_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	4jmo	CYTOHESIN-2 (Homo sapiens)	5 / 9	PHE A 147 SER A 150 TRP A 149 ARG A 152 LEU A 153	None None None JAF A 301 (-3.6A) JAF A 301 (-4.1A)	1.25A	2o01B-4jmoA: undetectable	2o01B-4jmoA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGQ_A_PCFA1275_0 (WNT INHIBITORY FACTOR 1)	4jmo	CYTOHESIN-2 (Homo sapiens)	5 / 12	ILE A 193 LEU A 148 ILE A 245 PRO A 246 VAL A 204	JAF A 301 (-3.7A) JAF A 301 (-3.9A) JAF A 301 (-3.9A) JAF A 301 (-4.7A) None	0.99A	2ygqA-4jmoA: undetectable	2ygqA-4jmoA: 21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9W_A_VGHA1158_1 (7,8-DIHYDRO-8-OXOGUA NINE TRIPHOSPHATASE)	4jmo	CYTOHESIN-2 (Homo sapiens)	5 / 12	LEU A 234 ASN A 139 PHE A 243 VAL A 192 GLN A 146	None None JAF A 301 ( 4.8A) None None	1.17A	4c9wA-4jmoA: undetectable	4c9wA-4jmoA: 24.31