SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IZA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FMO_E_ADNE351_1
(CAMP-DEPENDENT
PROTEIN KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
VAL A 911
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.76A 1fmoE-4gl9A:
24.2		 1fmoE-4gl9A:
24.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M17_A_AQ4A999_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
LEU A 927
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.80A 1m17A-4gl9A:
32.9		 1m17A-4gl9A:
34.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
GLY A 856
VAL A 863
ALA A 880
TYR A 931
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 ( 4.7A)
 0.74A 1muoA-4gl9A:
7.4		 1muoA-4gl9A:
27.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
ALA A 880
GLU A 898
VAL A 911
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 ( 4.7A)
 0.70A 1opjA-4gl9A:
19.7		 1opjA-4gl9A:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T46_A_STIA3_1
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
GLU A 898
LEU A 902
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.84A 1t46A-4gl9A:
21.9		 1t46A-4gl9A:
34.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T46_A_STIA3_1
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.82A 1t46A-4gl9A:
21.9		 1t46A-4gl9A:
34.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 7 ASN A 981
HIS A 974
PHE A 995
ILE A 960
 IZA  A2001 ( 4.7A)
None
None
None
 1.21A 1tdnA-4gl9A:
undetectable		 1tdnA-4gl9A:
22.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWH_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 ALA A 880
GLU A 898
LEU A 902
LEU A 967
HIS A 974
GLY A 993
 IZA  A2001 (-3.4A)
None
None
None
None
None
 1.00A 1uwhA-4gl9A:
26.4		 1uwhA-4gl9A:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWH_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 ALA A 880
LYS A 882
GLU A 898
LEU A 902
LEU A 967
HIS A 974
GLY A 993
 IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
None
None
 0.93A 1uwhB-4gl9A:
26.0		 1uwhB-4gl9A:
30.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 VAL A 863
ALA A 880
GLU A 898
LEU A 967
HIS A 974
GLY A 993
 None
IZA  A2001 (-3.4A)
None
None
None
None
 0.84A 1uwjA-4gl9A:
9.7		 1uwjA-4gl9A:
29.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 VAL A 863
ALA A 880
GLU A 898
LEU A 967
HIS A 974
GLY A 993
 None
IZA  A2001 (-3.4A)
None
None
None
None
 0.83A 1uwjB-4gl9A:
9.8		 1uwjB-4gl9A:
29.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
VAL A 863
ALA A 880
MET A 929
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.55A 1xbbA-4gl9A:
32.6		 1xbbA-4gl9A:
34.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 11 GLY A 856
GLY A 858
VAL A 863
ALA A 880
MET A 929
SER A 936
LEU A 983
 IZA  A2001 ( 4.9A)
IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
None
IZA  A2001 ( 4.7A)
 0.70A 2evaA-4gl9A:
26.7		 2evaA-4gl9A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 11 GLY A 856
GLY A 858
VAL A 863
ALA A 880
TYR A 931
SER A 936
LEU A 983
 IZA  A2001 ( 4.9A)
IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 ( 4.7A)
 0.68A 2evaA-4gl9A:
26.7		 2evaA-4gl9A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
ASP A 976
ASN A 981
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.76A 2fumA-4gl9A:
25.8		 2fumA-4gl9A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
MET A 929
TYR A 931
ASN A 981
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.73A 2fumB-4gl9A:
25.9		 2fumB-4gl9A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
MET A 929
ASN A 981
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
 0.79A 2fumC-4gl9A:
24.1		 2fumC-4gl9A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
MET A 929
TYR A 931
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
None
 0.68A 2fumC-4gl9A:
24.1		 2fumC-4gl9A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
GLY A 856
GLY A 858
VAL A 863
ALA A 880
MET A 929
ASN A 981
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
 0.87A 2fumD-4gl9A:
24.4		 2fumD-4gl9A:
24.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.66A 2gqgB-4gl9A:
32.3		 2gqgB-4gl9A:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 6 LEU A 855
LYS A 882
VAL A 911
ARG A 975
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.7A)
None
None
 1.03A 2hyyA-4gl9A:
20.2		 2hyyA-4gl9A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITO_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
LEU A 927
GLY A 935
ASP A 939
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
 0.80A 2itoA-4gl9A:
30.9		 2itoA-4gl9A:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		9 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LYS A 882
GLU A 898
LEU A 927
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.89A 2ityA-4gl9A:
31.0		 2ityA-4gl9A:
34.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
GLY A 935
ASP A 939
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
 0.69A 2itzA-4gl9A:
31.0		 2itzA-4gl9A:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 VAL A 863
ALA A 880
LYS A 882
GLU A 898
GLY A 935
ASP A 939
LEU A 983
ASP A 994
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.68A 2itzA-4gl9A:
31.0		 2itzA-4gl9A:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
GLY A 856
VAL A 863
LYS A 882
LEU A 902
TYR A 931
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 ( 4.7A)
 0.77A 2ivuA-4gl9A:
34.1		 2ivuA-4gl9A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
ALA A 880
GLY A 935
LEU A 983
GLY A 993
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.5A)
 0.64A 2xp2A-4gl9A:
29.2		 2xp2A-4gl9A:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
VAL A 863
ALA A 880
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.59A 2xp2A-4gl9A:
29.2		 2xp2A-4gl9A:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZVA_A_1N1A513_1
(TYROSINE-PROTEIN
KINASE LYN)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.73A 2zvaA-4gl9A:
29.9		 2zvaA-4gl9A:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BBT_D_FMMD91_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 VAL A 863
ALA A 880
LYS A 882
LEU A 927
GLY A 935
LEU A 983
PHE A 995
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 1.11A 3bbtD-4gl9A:
23.0		 3bbtD-4gl9A:
32.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BBT_D_FMMD91_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 VAL A 863
LYS A 882
LEU A 927
GLY A 935
LEU A 983
ASP A 994
PHE A 995
 None
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
None
 1.29A 3bbtD-4gl9A:
23.0		 3bbtD-4gl9A:
32.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 9 LEU A 855
VAL A 863
LYS A 882
VAL A 911
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.7A)
 0.60A 3cs9B-4gl9A:
28.4		 3cs9B-4gl9A:
36.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 6 LEU A 855
VAL A 863
LYS A 882
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.7A)
 0.73A 3cs9D-4gl9A:
20.7		 3cs9D-4gl9A:
36.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EYG_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		12 / 12 LEU A 855
GLY A 856
GLY A 858
GLY A 861
VAL A 863
ALA A 880
LYS A 882
MET A 929
SER A 936
ASN A 981
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
IZA  A2001 ( 3.7A)
None
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-4.4A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.68A 3eygA-4gl9A:
27.3		 3eygA-4gl9A:
54.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUP_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		11 / 12 LEU A 855
GLY A 856
GLY A 858
GLY A 861
VAL A 863
ALA A 880
LYS A 882
MET A 929
TYR A 931
SER A 936
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
IZA  A2001 ( 3.7A)
None
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-4.4A)
None
None
IZA  A2001 ( 4.5A)
 0.64A 3fupA-4gl9A:
41.7		 3fupA-4gl9A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUP_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		11 / 12 LEU A 855
GLY A 856
GLY A 861
VAL A 863
ALA A 880
LYS A 882
MET A 929
TYR A 931
SER A 936
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-4.4A)
None
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.67A 3fupA-4gl9A:
41.7		 3fupA-4gl9A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUP_B_MI1B1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		10 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LYS A 882
VAL A 911
MET A 929
TYR A 931
LEU A 932
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-4.4A)
None
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
 0.54A 3fupB-4gl9A:
29.1		 3fupB-4gl9A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUP_B_MI1B1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		9 / 12 LEU A 855
GLY A 856
VAL A 863
LYS A 882
VAL A 911
MET A 929
LEU A 932
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-4.4A)
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.65A 3fupB-4gl9A:
29.1		 3fupB-4gl9A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0E_A_B49A9000_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 11 LEU A 855
VAL A 863
ALA A 880
VAL A 911
TYR A 931
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.87A 3g0eA-4gl9A:
26.7		 3g0eA-4gl9A:
32.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0F_B_B49B9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 10 LEU A 855
VAL A 863
ALA A 880
TYR A 931
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.68A 3g0fB-4gl9A:
28.1		 3g0fB-4gl9A:
32.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_B_1N1B1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.70A 3g5dB-4gl9A:
29.3		 3g5dB-4gl9A:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
ALA A 880
GLU A 898
VAL A 911
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 ( 4.7A)
 0.65A 3gvuA-4gl9A:
20.8		 3gvuA-4gl9A:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXK_A_MI1A1125_1
(TYROSINE-PROTEIN
KINASE JAK3)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		9 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LYS A 882
VAL A 911
MET A 929
TYR A 931
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-4.4A)
None
IZA  A2001 ( 4.5A)
 0.72A 3lxkA-4gl9A:
29.6		 3lxkA-4gl9A:
57.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXK_A_MI1A1125_1
(TYROSINE-PROTEIN
KINASE JAK3)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
VAL A 911
MET A 929
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.94A 3lxkA-4gl9A:
29.6		 3lxkA-4gl9A:
57.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
GLY A 856
GLY A 858
VAL A 863
ALA A 880
LYS A 882
TYR A 931
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
 0.43A 3lxnA-4gl9A:
38.5		 3lxnA-4gl9A:
48.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LYS A 882
SER A 936
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.7A)
 0.49A 3lxnA-4gl9A:
38.5		 3lxnA-4gl9A:
48.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LYS A 882
TYR A 931
SER A 936
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
 0.44A 3lxnA-4gl9A:
38.5		 3lxnA-4gl9A:
48.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
ALA A 880
GLU A 898
VAL A 911
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 ( 4.7A)
 0.64A 3pyyB-4gl9A:
28.3		 3pyyB-4gl9A:
34.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
ALA A 880
VAL A 911
TYR A 931
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.60A 3sxrB-4gl9A:
29.0		 3sxrB-4gl9A:
33.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG2_A_IREA1_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		9 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
LEU A 927
MET A 929
GLY A 935
ASP A 939
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-4.4A)
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
 0.89A 3ug2A-4gl9A:
27.7		 3ug2A-4gl9A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 5 ILE A 901
VAL A 911
LEU A 983
ASP A 994
 None
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.86A 3wzdA-4gl9A:
28.2		 3wzdA-4gl9A:
33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 5 LYS A 882
ILE A 901
VAL A 911
LEU A 983
 IZA  A2001 ( 4.7A)
None
None
IZA  A2001 ( 4.7A)
 0.74A 3wzdA-4gl9A:
28.2		 3wzdA-4gl9A:
33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WZE_A_BAXA1201_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
ALA A 880
LEU A 902
GLY A 935
LEU A 967
HIS A 974
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-3.3A)
None
None
 0.74A 3wzeA-4gl9A:
28.8		 3wzeA-4gl9A:
33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WZE_A_BAXA1201_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLY A 935
LEU A 967
HIS A 974
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-3.3A)
None
None
 0.61A 3wzeA-4gl9A:
28.8		 3wzeA-4gl9A:
33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZBF_A_VGHA3000_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 ALA A 880
GLY A 935
LEU A 983
GLY A 993
ASP A 994
 IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.5A)
 0.41A 3zbfA-4gl9A:
30.4		 3zbfA-4gl9A:
33.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
LEU A 967
HIS A 974
ARG A 975
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
None
IZA  A2001 ( 4.7A)
 1.05A 3zosA-4gl9A:
28.0		 3zosA-4gl9A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 9 LEU A 855
ILE A 901
ILE A 910
TYR A 931
ILE A 992
 IZA  A2001 (-3.7A)
None
None
None
None
 0.69A 3zosB-4gl9A:
28.3		 3zosB-4gl9A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 9 LEU A 855
ILE A 901
LEU A 905
ILE A 910
ILE A 992
 IZA  A2001 (-3.7A)
None
None
None
None
 0.71A 3zosB-4gl9A:
28.3		 3zosB-4gl9A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.83A 4ag8A-4gl9A:
28.6		 4ag8A-4gl9A:
33.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
VAL A 863
ALA A 880
MET A 929
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.61A 4ansA-4gl9A:
28.8		 4ansA-4gl9A:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ASD_A_BAXA1500_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
GLY A 935
LEU A 967
HIS A 974
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
None
None
 0.85A 4asdA-4gl9A:
28.2		 4asdA-4gl9A:
30.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 5 LYS A 882
LEU A 905
TYR A 931
ARG A 975
 IZA  A2001 ( 4.7A)
None
None
None
 1.14A 4bkjB-4gl9A:
28.2		 4bkjB-4gl9A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CKJ_A_ADNA2014_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 10 LEU A 855
GLY A 856
VAL A 863
ALA A 880
TYR A 931
SER A 936
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 ( 4.7A)
 0.52A 4ckjA-4gl9A:
33.4		 4ckjA-4gl9A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I22_A_IREA9001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		10 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LYS A 882
LEU A 927
GLY A 935
ASP A 939
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.87A 4i22A-4gl9A:
28.1		 4i22A-4gl9A:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I22_A_IREA9001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		10 / 12 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LYS A 882
MET A 929
GLY A 935
ASP A 939
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-4.4A)
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.76A 4i22A-4gl9A:
28.1		 4i22A-4gl9A:
34.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KS8_A_B49A701_1
(SERINE/THREONINE-PRO
TEIN KINASE PAK 6)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 10 ALA A 880
VAL A 911
MET A 929
LEU A 932
GLY A 935
LEU A 983
 IZA  A2001 (-3.4A)
None
IZA  A2001 (-4.4A)
IZA  A2001 (-4.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.48A 4ks8A-4gl9A:
26.6		 4ks8A-4gl9A:
26.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.78A 4mxoB-4gl9A:
29.4		 4mxoB-4gl9A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 ALA A 880
LYS A 882
GLU A 898
VAL A 911
TYR A 931
GLY A 935
LEU A 983
 IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.72A 4mxxA-4gl9A:
29.5		 4mxxA-4gl9A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
LYS A 882
GLU A 898
VAL A 911
TYR A 931
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.7A)
None
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.87A 4mxxA-4gl9A:
29.5		 4mxxA-4gl9A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		10 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
TYR A 931
GLY A 935
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.93A 4mxyA-4gl9A:
30.0		 4mxyA-4gl9A:
31.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		10 / 12 VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
MET A 929
TYR A 931
GLY A 935
LEU A 983
ASP A 994
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-4.4A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.84A 4mxyA-4gl9A:
30.0		 4mxyA-4gl9A:
31.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		10 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
TYR A 931
GLY A 935
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.93A 4mxzA-4gl9A:
30.0		 4mxzA-4gl9A:
31.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		10 / 12 VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
MET A 929
TYR A 931
GLY A 935
LEU A 983
ASP A 994
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-4.4A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.84A 4mxzA-4gl9A:
30.0		 4mxzA-4gl9A:
31.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0S_A_ADNA500_1
(AURORA KINASE A)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 11 LEU A 855
GLY A 856
VAL A 863
LYS A 882
ASN A 981
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.92A 4o0sA-4gl9A:
27.3		 4o0sA-4gl9A:
27.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 6 LEU A 855
GLY A 856
VAL A 863
ALA A 880
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
 0.48A 4o0wA-4gl9A:
25.8		 4o0wA-4gl9A:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
LYS A 882
VAL A 911
GLY A 935
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.78A 4otwA-4gl9A:
28.1		 4otwA-4gl9A:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
VAL A 911
TYR A 931
GLY A 935
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
None
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.74A 4otwA-4gl9A:
28.1		 4otwA-4gl9A:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 11 ALA A 880
GLU A 898
MET A 929
TYR A 931
LEU A 932
ASP A 994
 IZA  A2001 (-3.4A)
None
IZA  A2001 (-4.4A)
None
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.5A)
 0.76A 4qmsA-4gl9A:
26.6		 4qmsA-4gl9A:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 11 ALA A 880
GLU A 898
TYR A 931
LEU A 932
LEU A 983
ASP A 994
 IZA  A2001 (-3.4A)
None
None
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.73A 4qmsA-4gl9A:
26.6		 4qmsA-4gl9A:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 11 ALA A 880
LYS A 882
GLU A 898
LEU A 932
LEU A 983
ASP A 994
 IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.76A 4qmsA-4gl9A:
26.6		 4qmsA-4gl9A:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 11 ALA A 880
LYS A 882
GLU A 898
MET A 929
LEU A 932
ASP A 994
 IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-4.4A)
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.5A)
 0.81A 4qmsA-4gl9A:
26.6		 4qmsA-4gl9A:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 GLY A 856
VAL A 863
ALA A 880
MET A 929
TYR A 931
LEU A 932
LEU A 983
 IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
None
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
 0.45A 4qmzA-4gl9A:
27.1		 4qmzA-4gl9A:
29.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 VAL A 863
ALA A 880
LYS A 882
GLU A 898
LEU A 983
GLY A 993
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.7A)
None
 0.78A 4r7iA-4gl9A:
28.2		 4r7iA-4gl9A:
30.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 5 LEU A 855
VAL A 911
TYR A 931
ARG A 975
 IZA  A2001 (-3.7A)
None
None
None
 0.94A 4r7iA-4gl9A:
28.2		 4r7iA-4gl9A:
30.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RZV_B_032B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 VAL A 863
ALA A 880
LYS A 882
SER A 936
GLY A 993
GLY A 996
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
 1.45A 4rzvB-4gl9A:
7.8		 4rzvB-4gl9A:
31.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RZV_B_032B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 VAL A 863
ALA A 880
LYS A 882
SER A 936
GLY A 993
PHE A 995
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
 1.02A 4rzvB-4gl9A:
7.8		 4rzvB-4gl9A:
31.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLY A 935
ASN A 981
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.66A 4twpA-4gl9A:
32.3		 4twpA-4gl9A:
36.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 6 LEU A 855
VAL A 863
LYS A 882
ILE A 910
ILE A 992
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
None
None
 0.60A 4tyjA-4gl9A:
22.1		 4tyjA-4gl9A:
33.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 10 LEU A 855
VAL A 863
GLU A 898
LEU A 905
ILE A 910
VAL A 911
TYR A 931
ILE A 992
 IZA  A2001 (-3.7A)
None
None
None
None
None
None
None
 0.75A 4u0iA-4gl9A:
16.6		 4u0iA-4gl9A:
34.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		9 / 11 LEU A 855
GLY A 861
VAL A 863
ALA A 880
TYR A 931
GLY A 935
ASN A 981
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
None
None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 1.28A 4u5jA-4gl9A:
31.3		 4u5jA-4gl9A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
VAL A 863
ALA A 880
TYR A 931
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.64A 4u5jB-4gl9A:
30.1		 4u5jB-4gl9A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 LEU A 855
ALA A 880
LEU A 967
HIS A 974
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
None
None
IZA  A2001 ( 4.7A)
 0.58A 4uxqA-4gl9A:
14.1		 4uxqA-4gl9A:
34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
VAL A 863
LYS A 882
TYR A 931
LEU A 983
ILE A 992
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.7A)
None
 0.63A 4v01A-4gl9A:
27.8		 4v01A-4gl9A:
35.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
VAL A 863
LYS A 882
TYR A 931
LEU A 983
ILE A 992
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.7A)
None
 0.57A 4v01B-4gl9A:
28.1		 4v01B-4gl9A:
35.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 8 LYS A 882
TYR A 931
LEU A 983
ILE A 992
 IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.7A)
None
 0.80A 4v04A-4gl9A:
27.5		 4v04A-4gl9A:
35.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 10 LEU A 855
VAL A 863
LYS A 882
TYR A 931
ARG A 975
LEU A 983
ILE A 992
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 ( 4.7A)
None
 1.21A 4v04B-4gl9A:
27.8		 4v04B-4gl9A:
35.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 8 LEU A 855
ALA A 880
MET A 929
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
 0.52A 4wboB-4gl9A:
22.9		 4wboB-4gl9A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 6 LEU A 855
ALA A 880
MET A 929
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 (-4.4A)
IZA  A2001 ( 4.7A)
 0.54A 4wboC-4gl9A:
23.2		 4wboC-4gl9A:
20.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WKQ_A_IREA1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
LEU A 927
GLY A 935
ASP A 939
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
 0.76A 4wkqA-4gl9A:
33.0		 4wkqA-4gl9A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_A_1N1A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.77A 4xeyA-4gl9A:
32.1		 4xeyA-4gl9A:
30.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 5 LEU A 983
GLU A 985
LEU A 902
HIS A 974
 IZA  A2001 ( 4.7A)
None
None
None
 1.13A 4xi3B-4gl9A:
undetectable		 4xi3B-4gl9A:
23.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.59A 4xliB-4gl9A:
26.4		 4xliB-4gl9A:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XV2_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 VAL A 863
ALA A 880
GLY A 993
ASP A 994
PHE A 995
 None
IZA  A2001 (-3.4A)
None
IZA  A2001 ( 4.5A)
None
 0.65A 4xv2A-4gl9A:
25.8		 4xv2A-4gl9A:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XV2_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 ALA A 880
LYS A 882
GLY A 993
ASP A 994
PHE A 995
 IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.5A)
None
 0.90A 4xv2B-4gl9A:
17.6		 4xv2B-4gl9A:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
ALA A 880
GLY A 935
LEU A 983
GLY A 993
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.5A)
 0.60A 5aaaA-4gl9A:
29.3		 5aaaA-4gl9A:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 9 LEU A 855
VAL A 863
ALA A 880
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.63A 5aaaA-4gl9A:
29.3		 5aaaA-4gl9A:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 10 LEU A 855
ALA A 880
LYS A 882
GLY A 935
LEU A 983
GLY A 993
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.5A)
 0.72A 5aabA-4gl9A:
29.1		 5aabA-4gl9A:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 10 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.68A 5aabA-4gl9A:
29.1		 5aabA-4gl9A:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAC_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 10 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.73A 5aacA-4gl9A:
29.1		 5aacA-4gl9A:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
TYR A 931
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.64A 5bvwA-4gl9A:
28.9		 5bvwA-4gl9A:
32.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 VAL A 863
ALA A 880
LYS A 882
GLY A 993
PHE A 995
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
 0.82A 5cswB-4gl9A:
25.5		 5cswB-4gl9A:
31.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
ALA A 880
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.63A 5h2uA-4gl9A:
26.8		 5h2uA-4gl9A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_B_1N1B501_1
(PROTEIN-TYROSINE
KINASE 6)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
ALA A 880
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.64A 5h2uB-4gl9A:
27.0		 5h2uB-4gl9A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_B_1N1B501_1
(PROTEIN-TYROSINE
KINASE 6)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
GLY A 935
LEU A 983
GLY A 993
ASP A 994
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.5A)
 0.73A 5h2uB-4gl9A:
27.0		 5h2uB-4gl9A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_C_1N1C501_1
(PROTEIN-TYROSINE
KINASE 6)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 LEU A 855
ALA A 880
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.59A 5h2uC-4gl9A:
26.8		 5h2uC-4gl9A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_D_1N1D504_1
(PROTEIN-TYROSINE
KINASE 6)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
ALA A 880
GLY A 935
LEU A 983
GLY A 993
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
None
 0.62A 5h2uD-4gl9A:
27.0		 5h2uD-4gl9A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HI2_A_BAXA801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 ALA A 880
LYS A 882
GLU A 898
LEU A 902
LEU A 967
HIS A 974
GLY A 993
 IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
None
None
 0.97A 5hi2A-4gl9A:
25.5		 5hi2A-4gl9A:
31.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 GLY A 858
VAL A 863
ALA A 880
LYS A 882
GLY A 993
 IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
 0.67A 5hieA-4gl9A:
25.1		 5hieA-4gl9A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 GLY A 858
VAL A 863
ALA A 880
LYS A 882
GLY A 993
 IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
 0.66A 5hieB-4gl9A:
25.1		 5hieB-4gl9A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 GLY A 856
GLY A 858
VAL A 863
ALA A 880
LYS A 882
GLY A 993
 IZA  A2001 ( 4.9A)
IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
 0.78A 5hieC-4gl9A:
25.6		 5hieC-4gl9A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 GLY A 856
VAL A 863
ALA A 880
LYS A 882
GLY A 993
ASP A 994
 IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 ( 4.5A)
 0.97A 5hieC-4gl9A:
25.6		 5hieC-4gl9A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 12 GLY A 858
VAL A 863
ALA A 880
LYS A 882
GLY A 993
 IZA  A2001 ( 3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
 0.68A 5hieD-4gl9A:
25.4		 5hieD-4gl9A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J5X_B_AZ1B2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAL-DAR-DAR-
DAR-DAR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		4 / 7 GLY A 856
VAL A 863
LYS A 882
ASP A 994
 IZA  A2001 ( 4.9A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.37A 5j5xA-4gl9A:
23.8		 5j5xA-4gl9A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LVN_A_ADNA402_1
(3-PHOSPHOINOSITIDE-D
EPENDENT PROTEIN
KINASE 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 11 LEU A 855
GLY A 856
VAL A 863
ALA A 880
TYR A 931
LEU A 983
 IZA  A2001 (-3.7A)
IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 ( 4.7A)
 0.49A 5lvnA-4gl9A:
26.2		 5lvnA-4gl9A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 GLY A 856
VAL A 863
ALA A 880
LYS A 882
GLU A 898
TYR A 931
GLY A 935
 IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
 0.81A 5mafA-4gl9A:
25.0		 5mafA-4gl9A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 10 LEU A 855
VAL A 863
LYS A 882
GLU A 898
GLY A 935
 IZA  A2001 (-3.7A)
None
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
 0.69A 5mo4A-4gl9A:
23.6		 5mo4A-4gl9A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 10 LEU A 855
VAL A 863
ALA A 880
VAL A 911
MET A 929
TYR A 931
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-4.4A)
None
IZA  A2001 ( 4.7A)
 0.69A 5n3hA-4gl9A:
24.0		 5n3hA-4gl9A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_1
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
VAL A 911
GLY A 993
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
None
 0.70A 5vcvA-4gl9A:
23.6		 5vcvA-4gl9A:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W5V_A_ANWA701_0
(SERINE/THREONINE-PRO
TEIN KINASE TBK1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		5 / 9 LEU A 855
ALA A 880
VAL A 911
MET A 929
GLY A 935
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
None
IZA  A2001 (-4.4A)
IZA  A2001 (-3.3A)
 0.79A 5w5vA-4gl9A:
12.3		 5w5vA-4gl9A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.79A 5y7zA-4gl9A:
24.7		 5y7zA-4gl9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
GLY A 935
LEU A 983
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.79A 5y7zA-4gl9A:
24.7		 5y7zA-4gl9A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_B_IREB401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
ALA A 880
LYS A 882
GLU A 898
LEU A 927
GLY A 935
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.80A 5y7zB-4gl9A:
24.7		 5y7zB-4gl9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		8 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
GLY A 935
LEU A 983
ASP A 994
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.76A 5y80A-4gl9A:
24.3		 5y80A-4gl9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_B_1E8B1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 GLY A 856
VAL A 863
ALA A 880
LEU A 927
ASP A 939
LEU A 983
 IZA  A2001 ( 4.9A)
None
IZA  A2001 (-3.4A)
None
None
IZA  A2001 ( 4.7A)
 0.89A 5yu9B-4gl9A:
28.2		 5yu9B-4gl9A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_C_1E8C1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 VAL A 863
ALA A 880
LEU A 927
GLY A 935
ASP A 939
ASP A 994
 None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.5A)
 1.09A 5yu9C-4gl9A:
21.7		 5yu9C-4gl9A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_D_1E8D1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 VAL A 863
ALA A 880
GLY A 935
ASP A 939
LEU A 983
ASP A 994
 None
IZA  A2001 (-3.4A)
IZA  A2001 (-3.3A)
None
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
 0.76A 5yu9D-4gl9A:
28.8		 5yu9D-4gl9A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		7 / 12 VAL A 863
ALA A 880
LYS A 882
GLU A 898
TYR A 931
GLY A 935
LEU A 983
 None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
 0.67A 6bsdA-4gl9A:
28.5		 6bsdA-4gl9A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 4gl9 TYROSINE-PROTEIN
KINASE
(Mus
musculus) 		6 / 12 LEU A 855
VAL A 863
ALA A 880
LYS A 882
GLU A 898
VAL A 911
 IZA  A2001 (-3.7A)
None
IZA  A2001 (-3.4A)
IZA  A2001 ( 4.7A)
None
None
 0.53A 6hd6B-4gl9A:
27.4		 6hd6B-4gl9A:
15.38