SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IXW'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTZ_A_LDPA501_1 (CYTOCHROME P450 BM3 VARIANT 8C8)	4ixw	HALOHYDRIN DEHALOGENASE (Agrobacterium tumefaciens)	4 / 6	ALA A 150 ALA A 174 PRO A 175 THR A 131	None None IXW A 302 (-4.6A) None	0.71A	4dtzA-4ixwA: undetectable	4dtzA-4ixwA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTZ_B_LDPB501_1 (CYTOCHROME P450 BM3 VARIANT 8C8)	4ixw	HALOHYDRIN DEHALOGENASE (Agrobacterium tumefaciens)	4 / 6	ALA A 150 ALA A 174 PRO A 175 THR A 131	None None IXW A 302 (-4.6A) None	0.71A	4dtzB-4ixwA: undetectable	4dtzB-4ixwA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DU2_A_LDPA501_1 (CYTOCHROME P450 BM3 VARIANT B7)	4ixw	HALOHYDRIN DEHALOGENASE (Agrobacterium tumefaciens)	5 / 7	ALA A 134 ALA A 150 ALA A 174 PRO A 175 THR A 131	IXW A 302 (-3.5A) None None IXW A 302 (-4.6A) None	1.04A	4du2A-4ixwA: undetectable	4du2A-4ixwA: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DU2_B_LDPB501_1 (CYTOCHROME P450 BM3 VARIANT B7)	4ixw	HALOHYDRIN DEHALOGENASE (Agrobacterium tumefaciens)	5 / 7	ALA A 134 ALA A 150 ALA A 174 PRO A 175 THR A 131	IXW A 302 (-3.5A) None None IXW A 302 (-4.6A) None	1.06A	4du2B-4ixwA: undetectable	4du2B-4ixwA: 20.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4DTZ_A_LDPA501_1","CYTOCHROME P450 BM3 VARIANT 8C8","4ixw","HALOHYDRIN DEHALOGENASE","Agrobacterium tumefaciens",4,"ALA A 150;ALA A 174;PRO A 175;THR A 131","None;None;IXW A 302 (-4.6A);None","0.71A","4dtzA-4ixwA:undetectable",null],["4DTZ_B_LDPB501_1","CYTOCHROME P450 BM3 VARIANT 8C8","4ixw","HALOHYDRIN DEHALOGENASE","Agrobacterium tumefaciens",4,"ALA A 150;ALA A 174;PRO A 175;THR A 131","None;None;IXW A 302 (-4.6A);None","0.71A","4dtzB-4ixwA:undetectable","4dtzA-4ixwA:19.75"],["4DU2_A_LDPA501_1","CYTOCHROME P450 BM3 VARIANT B7","4ixw","HALOHYDRIN DEHALOGENASE","Agrobacterium tumefaciens",5,"ALA A 134;ALA A 150;ALA A 174;PRO A 175;THR A 131","IXW A 302 (-3.5A);None;None;IXW A 302 (-4.6A);None","1.04A","4du2A-4ixwA:undetectable","4dtzB-4ixwA:19.75"],["4DU2_B_LDPB501_1","CYTOCHROME P450 BM3 VARIANT B7","4ixw","HALOHYDRIN DEHALOGENASE","Agrobacterium tumefaciens",5,"ALA A 134;ALA A 150;ALA A 174;PRO A 175;THR A 131","IXW A 302 (-3.5A);None;None;IXW A 302 (-4.6A);None","1.06A","4du2B-4ixwA:undetectable","4du2A-4ixwA:20.89"]]