SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IXO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.6A)
 1.08A 3rzeA-4mqtA:
29.4		 3rzeA-4mqtA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
TYR A 430
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.5A)
 0.81A 3rzeA-4mqtA:
29.4		 3rzeA-4mqtA:
28.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
THR A 187
ALA A 194
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
 1.25A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
THR A 187
ALA A 194
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
None
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
 0.90A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
TRP A 155
THR A 187
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-4.6A)
 1.28A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
TRP A 155
THR A 187
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
 0.87A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 194
ASN A 404
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
 0.91A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 194
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.16A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
ALA A 194
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
 1.12A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
ALA A 194
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
 0.85A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 155
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.6A)
 1.06A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 155
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
2CU  A 502 ( 3.9A)
 0.74A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
TRP A 400
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.5A)
 1.17A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.98A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 400
TYR A 403
ASN A 404
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
IXO  A 501 (-3.5A)
 1.20A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.06A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 194
ASN A 404
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
 0.93A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 194
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.22A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
THR A 187
TRP A 400
TYR A 403
ASN A 404
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
IXO  A 501 (-3.5A)
 1.20A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
THR A 187
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.04A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
TRP A 155
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.28A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
TRP A 155
THR A 187
TRP A 400
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.5A)
 1.25A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
TRP A 155
THR A 187
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.02A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 TYR A 104
SER A 107
ASN A 108
TRP A 155
TYR A 426
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
2CU  A 502 ( 3.9A)
 1.19A 4dajA-4mqtA:
32.7		 4dajA-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
SER A 107
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.38A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
SER A 107
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.06A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.24A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
THR A 187
THR A 190
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.93A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 194
ASN A 404
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
 0.97A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 194
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.27A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.97A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.20A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.38A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
THR A 187
THR A 190
ALA A 194
ASN A 404
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
 0.93A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
THR A 187
THR A 190
ALA A 194
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.21A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
THR A 187
THR A 190
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.81A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
TRP A 155
ALA A 191
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
 1.09A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
TRP A 155
THR A 187
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-4.6A)
 1.32A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
TRP A 155
THR A 187
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
 0.91A 4dajB-4mqtA:
32.3		 4dajB-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
ASN A 108
THR A 187
THR A 190
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
None
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.93A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
ASN A 108
THR A 187
THR A 190
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.24A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
SER A 107
ASN A 108
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.01A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
SER A 107
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.41A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
SER A 107
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.10A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
THR A 187
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.50A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.31A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
THR A 187
THR A 190
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.03A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
THR A 190
TYR A 403
ASN A 404
CYH A 429
 IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
IXO  A 501 (-3.5A)
 1.26A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
THR A 187
THR A 190
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
None
None
IXO  A 501 (-4.6A)
 1.10A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
ASN A 108
THR A 187
THR A 190
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
None
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.84A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
TRP A 155
THR A 187
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-4.6A)
 1.28A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
TRP A 155
THR A 187
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
 0.93A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-4.6A)
 1.12A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.86A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
THR A 187
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.19A 4dajC-4mqtA:
25.8		 4dajC-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
SER A 107
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.29A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
SER A 107
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.08A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.23A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
THR A 187
THR A 190
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.03A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
THR A 190
TYR A 403
ASN A 404
CYH A 429
 IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
IXO  A 501 (-3.5A)
 1.29A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 ASP A 103
TYR A 104
ASN A 108
THR A 187
THR A 190
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
None
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.95A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
ASN A 108
THR A 187
THR A 190
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.15A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
ASN A 108
TRP A 155
THR A 187
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-4.6A)
 1.23A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
ASN A 108
TRP A 155
THR A 187
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.98A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.96A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 155
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.6A)
 1.06A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 155
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-3.6A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.91A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.15A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.48A 4dajD-4mqtA:
33.1		 4dajD-4mqtA:
44.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 LEU A 100
ASP A 103
SER A 107
ALA A 194
TRP A 400
 None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
 0.57A 4nc3A-4mqtA:
29.2		 4nc3A-4mqtA:
28.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.17A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 191
ALA A 194
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
 0.99A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 191
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.99A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 191
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.23A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
TRP A 155
ALA A 191
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
 1.13A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ILE A  72
ASP A 103
TYR A 104
THR A 187
ALA A 191
ALA A 194
TYR A 426
 None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
 0.98A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 ILE A  72
ASP A 103
TYR A 104
THR A 187
ALA A 191
ASN A 404
TYR A 426
CYH A 429
 None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.89A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ILE A  72
ASP A 103
TYR A 104
THR A 187
ALA A 191
TRP A 400
ASN A 404
 None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.13A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ILE A  72
ASP A 103
TYR A 104
TRP A 155
THR A 187
TRP A 400
 None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-4.6A)
 1.34A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ILE A  72
ASP A 103
TYR A 104
TRP A 155
THR A 187
TYR A 426
 None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
 1.03A 4u14A-4mqtA:
33.1		 4u14A-4mqtA:
45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		9 / 12 ASP A 103
TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 191
ALA A 194
ASN A 404
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
 0.95A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		9 / 12 ASP A 103
TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 191
ALA A 194
TRP A 400
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.13A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		9 / 12 ASP A 103
TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 191
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.87A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-4.6A)
 1.28A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.02A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.18A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.39A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
TRP A 155
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.38A 4u15A-4mqtA:
33.3		 4u15A-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
THR A 190
ALA A 191
ALA A 194
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
 1.09A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 ASP A 103
TYR A 104
SER A 107
THR A 190
ALA A 191
ALA A 194
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.88A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 ASP A 103
TYR A 104
SER A 107
THR A 190
ALA A 191
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.14A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		9 / 12 ASP A 103
TYR A 104
SER A 107
THR A 190
ALA A 191
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.98A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.21A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
THR A 187
THR A 190
ALA A 191
ALA A 194
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.5A)
 0.90A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 ASP A 103
TYR A 104
THR A 187
THR A 190
ALA A 191
TYR A 403
ASN A 404
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
IXO  A 501 (-3.5A)
 0.96A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 THR A 187
THR A 190
ALA A 191
ALA A 193
TYR A 403
 None
None
None
None
IXO  A 501 (-3.8A)
 1.38A 4u15B-4mqtA:
33.6		 4u15B-4mqtA:
49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 191
ALA A 194
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.79A 5cxvA-4mqtA:
32.6		 5cxvA-4mqtA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
ALA A 191
TRP A 400
ASN A 404
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
 0.90A 5cxvA-4mqtA:
32.6		 5cxvA-4mqtA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
ALA A 194
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.75A 5cxvA-4mqtA:
32.6		 5cxvA-4mqtA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
TRP A 400
TYR A 426
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.6A)
2CU  A 502 ( 3.9A)
 0.93A 5cxvA-4mqtA:
32.6		 5cxvA-4mqtA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
TRP A 155
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.36A 5cxvA-4mqtA:
32.6		 5cxvA-4mqtA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
ALA A 191
TRP A 400
TYR A 403
ASN A 404
TYR A 426
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
 1.07A 5cxvA-4mqtA:
32.6		 5cxvA-4mqtA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
ALA A 191
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.90A 5cxvA-4mqtA:
32.6		 5cxvA-4mqtA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
THR A 187
THR A 190
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.87A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.01A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
None
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.30A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
TRP A 155
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.45A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 194
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.81A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 194
TRP A 400
ASN A 404
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.00A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.12A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		8 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.94A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 TYR A 104
SER A 107
TRP A 155
THR A 187
ALA A 194
TRP A 400
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
 1.13A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
TRP A 155
THR A 187
ALA A 194
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.93A 5dsgA-4mqtA:
32.8		 5dsgA-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 194
ASN A 404
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
IXO  A 501 (-3.5A)
 0.77A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 194
TRP A 400
ASN A 404
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
IXO  A 501 (-3.0A)
 1.00A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-4.6A)
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
 1.11A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
TYR A 403
ASN A 404
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
IXO  A 501 (-3.5A)
 0.91A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 190
ALA A 194
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.70A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		7 / 12 TYR A 104
SER A 107
THR A 190
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
None
IXO  A 501 (-3.8A)
IXO  A 501 (-3.0A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.87A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 TYR A 104
SER A 107
TRP A 155
ALA A 194
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-3.5A)
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 0.74A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 TYR A 104
SER A 107
TRP A 155
THR A 187
ALA A 194
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-3.5A)
 0.93A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		6 / 12 TYR A 104
SER A 107
TRP A 155
THR A 187
ALA A 194
TRP A 400
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
None
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
 1.15A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 TYR A 104
THR A 187
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
None
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.28A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 TYR A 104
TRP A 155
ALA A 191
TYR A 426
CYH A 429
 IXO  A 501 (-3.7A)
IXO  A 501 (-3.6A)
None
2CU  A 502 ( 3.9A)
IXO  A 501 (-3.5A)
 1.44A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		3 / 3 ASP A 103
ASN A 108
PHE A 195
 IXO  A 501 (-3.4A)
IXO  A 501 (-4.3A)
None
 0.78A 5dsgB-4mqtA:
33.7		 5dsgB-4mqtA:
60.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		4 / 7 TYR A 430
TYR A 403
TRP A  99
LEU A 100
 IXO  A 501 (-4.5A)
IXO  A 501 (-3.8A)
None
None
 1.49A 6cnkB-4mqtA:
undetectable
6cnkC-4mqtA:
undetectable		 6cnkB-4mqtA:
12.46
6cnkC-4mqtA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 TRP A  99
LEU A 100
SER A 107
ALA A 194
TRP A 400
 None
None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.5A)
IXO  A 501 (-4.6A)
 0.60A 6drxA-4mqtA:
29.0		 6drxA-4mqtA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2
(Homo
sapiens) 		5 / 12 TRP A  99
LEU A 100
SER A 107
ALA A 194
TYR A 430
 None
None
IXO  A 501 (-3.4A)
IXO  A 501 (-3.5A)
IXO  A 501 (-4.5A)
 0.76A 6drxA-4mqtA:
29.0		 6drxA-4mqtA:
27.42