SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IVH'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GP0_A_NILA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3pn1	DNA LIGASE (Haemophilus influenzae)	4 / 7	VAL A 171 LEU A 117 MET A 79 ILE A 228	None IVH A 319 (-4.7A) None None	0.90A	3gp0A-3pn1A: undetectable	3gp0A-3pn1A: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QWU_A_ADNA501_1 (DNA LIGASE)	3pn1	DNA LIGASE (Haemophilus influenzae)	5 / 12	GLU A 114 LYS A 116 GLU A 174 VAL A 289 LYS A 291	IVH A 319 (-3.6A) IVH A 319 (-3.7A) IVH A 319 (-2.9A) IVH A 319 (-4.4A) IVH A 319 (-3.0A)	0.55A	3qwuA-3pn1A: 10.2	3qwuA-3pn1A: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QWU_B_ADNB501_1 (DNA LIGASE)	3pn1	DNA LIGASE (Haemophilus influenzae)	5 / 11	GLU A 114 LYS A 116 ARG A 137 GLU A 174 LYS A 291	IVH A 319 (-3.6A) IVH A 319 (-3.7A) None IVH A 319 (-2.9A) IVH A 319 (-3.0A)	0.70A	3qwuB-3pn1A: 10.8	3qwuB-3pn1A: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QWU_B_ADNB501_1 (DNA LIGASE)	3pn1	DNA LIGASE (Haemophilus influenzae)	5 / 11	GLU A 114 LYS A 116 GLU A 174 VAL A 289 LYS A 291	IVH A 319 (-3.6A) IVH A 319 (-3.7A) IVH A 319 (-2.9A) IVH A 319 (-4.4A) IVH A 319 (-3.0A)	0.35A	3qwuB-3pn1A: 10.8	3qwuB-3pn1A: 23.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3GP0_A_NILA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 11","3pn1","DNA LIGASE","Haemophilus influenzae",4,"VAL A 171;LEU A 117;MET A  79;ILE A 228","None;IVH A 319 (-4.7A);None;None","0.90A","3gp0A-3pn1A:undetectable",null],["3QWU_A_ADNA501_1","DNA LIGASE","3pn1","DNA LIGASE","Haemophilus influenzae",5,"GLU A 114;LYS A 116;GLU A 174;VAL A 289;LYS A 291","IVH A 319 (-3.6A);IVH A 319 (-3.7A);IVH A 319 (-2.9A);IVH A 319 (-4.4A);IVH A 319 (-3.0A)","0.55A","3qwuA-3pn1A:10.2","3gp0A-3pn1A:21.60"],["3QWU_B_ADNB501_1","DNA LIGASE","3pn1","DNA LIGASE","Haemophilus influenzae",5,"GLU A 114;LYS A 116;ARG A 137;GLU A 174;LYS A 291","IVH A 319 (-3.6A);IVH A 319 (-3.7A);None;IVH A 319 (-2.9A);IVH A 319 (-3.0A)","0.70A","3qwuB-3pn1A:10.8","3qwuA-3pn1A:23.87"],["3QWU_B_ADNB501_1","DNA LIGASE","3pn1","DNA LIGASE","Haemophilus influenzae",5,"GLU A 114;LYS A 116;GLU A 174;VAL A 289;LYS A 291","IVH A 319 (-3.6A);IVH A 319 (-3.7A);IVH A 319 (-2.9A);IVH A 319 (-4.4A);IVH A 319 (-3.0A)","0.35A","3qwuB-3pn1A:10.8","3qwuB-3pn1A:23.87"]]