SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IUL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 5a8z NEUTROPHIL ELASTASE
(Homo
sapiens) 		5 / 12 GLY A 140
SER A  32
SER A 195
ALA A 138
ILE A  16
 None
None
IUL  A1001 (-3.3A)
None
None
 1.16A 1nt2A-5a8zA:
undetectable		 1nt2A-5a8zA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 5a8z NEUTROPHIL ELASTASE
(Homo
sapiens) 		5 / 11 ALA A 213
TYR A  94
ALA A  55
GLY A 196
SER A 195
 IUL  A1001 (-3.6A)
IUL  A1001 (-4.7A)
None
None
IUL  A1001 (-3.3A)
 1.41A 2xfsB-5a8zA:
undetectable		 2xfsB-5a8zA:
19.61