SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'INS'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_E_ACTE3005_0 (BETA-CARBONIC ANHYDRASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	4 / 7	ASP A 219 GLY A  26 GLY A  25 GLN A 136	INS  A 301 (-2.7A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) MG  A 303 ( 2.9A)	0.96A	1ekjE-4xf7A: undetectable 1ekjF-4xf7A: undetectable	1ekjE-4xf7A: 23.49 1ekjF-4xf7A: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_G_ACTG3002_0 (BETA-CARBONIC ANHYDRASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	4 / 8	ASP A 219 GLY A  26 GLY A  25 GLN A 136	INS  A 301 (-2.7A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) MG  A 303 ( 2.9A)	0.92A	1ekjG-4xf7A: undetectable 1ekjH-4xf7A: undetectable	1ekjG-4xf7A: 23.49 1ekjH-4xf7A: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LII_A_ADNA699_1 (ADENOSINE KINASE)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	ASP A  11 GLY A  25 GLY A  26 THR A  74 ASN A  78	INS  A 301 (-2.7A) INS  A 301 (-3.4A) INS  A 301 (-3.8A) None INS  A 301 (-3.0A)	0.88A	1liiA-5ysqA: 22.9	1liiA-5ysqA: 12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIK_A_ADNA699_1 (ADENOSINE KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A  73 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) None INS  A 301 (-2.7A)	1.16A	1likA-4xf7A: 22.9	1likA-4xf7A: 23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIK_A_ADNA699_1 (ADENOSINE KINASE)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	LEU A  37 GLY A 231 GLY A 233 THR A  33 ASN A 114	None INS  A 301 ( 4.7A) SO4  A 302 (-3.2A) None None	1.01A	1likA-5ysqA: 24.6	1likA-5ysqA: 12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXG_A_ACRA442_1 (ALPHA AMYLASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 11	GLY A 223 PHE A 248 GLY A 218 GLY A  27 GLY A  26	None None ACP  A 302 (-3.2A) INS  A 301 (-3.8A) INS  A 301 (-3.1A)	1.01A	1mxgA-4xf7A: undetectable	1mxgA-4xf7A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_A_MTLA870_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.18A	1p6kA-4irxA: undetectable	1p6kA-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.22A	1p6kB-4irxA: undetectable	1p6kB-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PJ7_A_FFOA2887_1 (N,N-DIMETHYLGLYCINE OXIDASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	3 / 3	ASP A  12 THR A  73 GLU A 115	INS  A 301 (-2.8A) None None	0.84A	1pj7A-4xf7A: 5.3	1pj7A-4xf7A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS6_A_MTLA870_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.16A	1rs6A-4irxA: undetectable	1rs6A-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS6_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.21A	1rs6B-4irxA: undetectable	1rs6B-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_C_CHDC3271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE III CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	5 / 8	LEU A  31 GLN A  69 PHE A  29 LEU A  42 PHE A  38	None None None None INS  A 401 (-4.5A)	1.15A	1v54C-4rxmA: undetectable 1v54J-4rxmA: undetectable	1v54C-4rxmA: 20.81 1v54J-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_P_CHDP4271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE III CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 8	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.91A	1v54P-4rxmA: undetectable 1v54W-4rxmA: undetectable	1v54P-4rxmA: 20.81 1v54W-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_A_TFPA204_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 7	PHE A 164 PHE A  63 VAL A 280 SER A 241	None None None INS  A 402 ( 4.7A)	0.99A	1wrlA-4rv3A: undetectable 1wrlB-4rv3A: undetectable	1wrlA-4rv3A: 14.78 1wrlB-4rv3A: 14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZQ_A_MTLA870_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.22A	1zzqA-4irxA: undetectable	1zzqA-4irxA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZQ_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.22A	1zzqB-4irxA: undetectable	1zzqB-4irxA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZU_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.22A	1zzuB-4irxA: undetectable	1zzuB-4irxA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C49_A_ADNA1301_1 (SUGAR KINASE MJ0406)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	ASP A  11 GLY A  25 GLY A  26 GLN A 141 ASP A 234	INS  A 301 (-2.7A) INS  A 301 (-3.4A) INS  A 301 (-3.8A) INS  A 301 (-3.0A) INS  A 301 ( 4.9A)	0.96A	2c49A-5ysqA: 26.6	2c49A-5ysqA: 14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CP4_A_CAMA416_0 (CYTOCHROME P450-CAM)	5ysq	TM0415 (Thermotoga maritima)	5 / 10	PHE A  98 THR A  74 LEU A 116 GLY A  26 VAL A  43	None None INS  A 301 (-4.8A) INS  A 301 (-3.8A) None	1.30A	2cp4A-5ysqA: undetectable	2cp4A-5ysqA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	5 / 8	LEU A  31 GLN A  69 PHE A  29 LEU A  42 PHE A  38	None None None None INS  A 401 (-4.5A)	1.16A	2dyrC-4rxmA: undetectable 2dyrJ-4rxmA: undetectable	2dyrC-4rxmA: 20.81 2dyrJ-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 7	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.96A	2eimP-4rxmA: undetectable 2eimW-4rxmA: undetectable	2eimP-4rxmA: 20.81 2eimW-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OKC_A_SAMA500_1 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	5ysq	TM0415 (Thermotoga maritima)	4 / 6	THR A 230 THR A 235 ASN A  61 ASP A  60	INS  A 301 (-4.7A) None None None	1.28A	2okcA-5ysqA: 2.8	2okcA-5ysqA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PKK_A_2FAA501_1 (ADENOSINE KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 GLY A 216 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) ACP  A 302 (-3.9A) INS  A 301 (-2.7A)	0.70A	2pkkA-4xf7A: 26.9	2pkkA-4xf7A: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PKM_A_ADNA501_1 (ADENOSINE KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 GLY A 216 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) ACP  A 302 (-3.9A) INS  A 301 (-2.7A)	0.71A	2pkmA-4xf7A: 27.0	2pkmA-4xf7A: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RK8_B_PPFB3969_1 (PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP])	2huo	INOSITOL OXYGENASE (Mus musculus)	4 / 7	LYS A 127 HIS A 220 SER A 221 ASP A 124	INS  A 303 (-2.6A) FE  A 302 (-3.2A) INS  A 303 (-2.8A) FE  A 302 ( 2.5A)	1.41A	2rk8B-2huoA: undetectable	2rk8B-2huoA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_A_QPSA1050_1 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 PHE A 156 TYR A  31 ASP A 142 HIS A  48	INS  A 303 (-3.7A) None None INS  A 303 (-3.5A) None	1.43A	2x2iA-2huoA: undetectable	2x2iA-2huoA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_B_2FAB500_1 (ADENOSYLHOMOCYSTEINA SE)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.47A	2zj0B-2huoA: undetectable	2zj0B-2huoA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 6	LEU A  31 GLN A  69 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	1.02A	2zxwP-4rxmA: undetectable 2zxwW-4rxmA: undetectable	2zxwP-4rxmA: 20.81 2zxwW-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A25_A_SAMA279_0 (UNCHARACTERIZED PROTEIN PH0793)	4yo7	SUGAR ABC TRANSPORTER (SUGAR-BINDING PROTEIN) (Bacillus halodurans)	5 / 12	ASN A 233 ARG A 183 GLY A 176 ASP A 108 THR A 109	INS  A 405 (-3.8A) INS  A 405 (-2.6A) None None None	1.40A	3a25A-4yo7A: undetectable	3a25A-4yo7A: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 6	LEU A  31 GLN A  69 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	1.01A	3ag1C-4rxmA: undetectable 3ag1J-4rxmA: undetectable	3ag1C-4rxmA: 20.81 3ag1J-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 7	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.97A	3asnC-4rxmA: undetectable 3asnJ-4rxmA: undetectable	3asnC-4rxmA: 20.81 3asnJ-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_P_CHDP1271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 7	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.92A	3asnP-4rxmA: undetectable 3asnW-4rxmA: undetectable	3asnP-4rxmA: 20.81 3asnW-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_P_CHDP1271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 7	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.93A	3asoP-4rxmA: undetectable 3asoW-4rxmA: undetectable	3asoP-4rxmA: 20.81 3asoW-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9M_A_SALA1200_1 (SERUM ALBUMIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	4 / 5	ILE A 147 TYR A  75 ARG A  92 GLY A 137	None INS  A 301 (-3.8A) None None	1.25A	3b9mA-4xf7A: undetectable	3b9mA-4xf7A: 17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_B_ADNB500_1 (ADENOSYLHOMOCYSTEINA SE)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.45A	3ce6B-2huoA: undetectable	3ce6B-2huoA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_A_RABA602_1 (ADENOSYLHOMOCYSTEINA SE)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.42A	3glqA-2huoA: undetectable	3glqA-2huoA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_B_RABB602_1 (ADENOSYLHOMOCYSTEINA SE)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.43A	3glqB-2huoA: undetectable	3glqB-2huoA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILT_B_TRUB800_1 (GLUTAMATE RECEPTOR 2)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	5 / 12	PRO A  32 SER A  64 LEU A  42 LEU A  34 SER A  36	None None None None INS  A 401 ( 4.4A)	1.36A	3iltB-4rxmA: 2.1 3iltE-4rxmA: 3.4	3iltB-4rxmA: 21.81 3iltE-4rxmA: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWQ_D_VIAD901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	5 / 11	GLN A 278 HIS A 137 LEU A 306 MET A  55 LEU A  59	INS  A 401 (-3.1A) None None None None	1.48A	3jwqA-4irxA: undetectable 3jwqD-4irxA: undetectable	3jwqA-4irxA: 24.31 3jwqD-4irxA: 24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_A_PZIA802_0 (GLUTAMATE RECEPTOR 2)	5fyr	PHOSPHOINOSITOL-SPEC IFIC PHOSPHOLIPASE C (Pseudomonas sp.)	3 / 3	ASP A 119 ASN A  27 SER A 191	INS  A 301 ( 3.1A) CA  A 401 ( 3.0A) None	0.84A	3lslA-5fyrA: undetectable 3lslD-5fyrA: undetectable	3lslA-5fyrA: 19.69 3lslD-5fyrA: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_D_PZID802_0 (GLUTAMATE RECEPTOR 2)	5fyr	PHOSPHOINOSITOL-SPEC IFIC PHOSPHOLIPASE C (Pseudomonas sp.)	3 / 3	SER A 191 ASP A 119 ASN A  27	None INS  A 301 ( 3.1A) CA  A 401 ( 3.0A)	0.92A	3lslA-5fyrA: undetectable 3lslD-5fyrA: undetectable	3lslA-5fyrA: 19.69 3lslD-5fyrA: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_C_ADNC500_1 (ADENOSYLHOMOCYSTEINA SE)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.41A	3n58C-2huoA: undetectable	3n58C-2huoA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_D_ADND500_1 (ADENOSYLHOMOCYSTEINA SE)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.41A	3n58D-2huoA: undetectable	3n58D-2huoA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UBO_B_ADNB353_1 (ADENOSINE KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	3uboB-4xf7A: 24.4	3uboB-4xf7A: 23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 6	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.96A	3wg7C-4rxmA: undetectable 3wg7J-4rxmA: undetectable	3wg7C-4rxmA: 20.81 3wg7J-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 6	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.99A	3wg7P-4rxmA: undetectable 3wg7W-4rxmA: undetectable	3wg7P-4rxmA: 20.81 3wg7W-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_G_ACTG305_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	ASP A 115 ARG A 166 LYS A 113	None INS  A 402 (-2.6A) INS  A 402 (-3.9A)	1.15A	3wipG-4rv3A: undetectable	3wipG-4rv3A: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DC3_B_2FAB401_1 (ADENOSINE KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	6 / 12	ASP A  12 GLY A  25 GLY A  26 LEU A  89 GLY A 216 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) None ACP  A 302 (-3.9A) INS  A 301 (-2.7A)	1.25A	4dc3B-4xf7A: 22.9	4dc3B-4xf7A: 21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DC3_B_2FAB401_1 (ADENOSINE KINASE)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	ASP A  11 GLY A  25 GLY A  26 THR A  74 ASN A  78	INS  A 301 (-2.7A) INS  A 301 (-3.4A) INS  A 301 (-3.8A) None INS  A 301 (-3.0A)	0.83A	4dc3B-5ysqA: 24.8	4dc3B-5ysqA: 10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3A_A_ADNA500_1 (SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A  73 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) None INS  A 301 (-2.7A)	1.09A	4e3aA-4xf7A: 24.5	4e3aA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3A_A_ADNA500_1 (SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.74A	4e3aA-4xf7A: 24.5	4e3aA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3A_B_ADNB500_1 (SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	6 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 GLY A 216 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) ACP  A 302 (-3.9A) INS  A 301 (-2.7A)	0.71A	4e3aB-4xf7A: 24.4	4e3aB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3A_B_ADNB500_1 (SUGAR KINASE PROTEIN)	5ysq	TM0415 (Thermotoga maritima)	6 / 12	ASP A  11 GLY A  25 GLY A  26 THR A 230 GLY A 231 ASP A 234	INS  A 301 (-2.7A) INS  A 301 (-3.4A) INS  A 301 (-3.8A) INS  A 301 (-4.7A) INS  A 301 ( 4.7A) INS  A 301 ( 4.9A)	1.08A	4e3aB-5ysqA: 27.8	4e3aB-5ysqA: 12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3A_B_ADNB500_1 (SUGAR KINASE PROTEIN)	5ysq	TM0415 (Thermotoga maritima)	6 / 12	GLY A  25 GLY A  26 LEU A  91 THR A 230 GLY A 231 ASP A 234	INS  A 301 (-3.4A) INS  A 301 (-3.8A) None INS  A 301 (-4.7A) INS  A 301 ( 4.7A) INS  A 301 ( 4.9A)	1.23A	4e3aB-5ysqA: 27.8	4e3aB-5ysqA: 12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H2F_A_ADNA601_1 (5'-NUCLEOTIDASE)	5ysq	TM0415 (Thermotoga maritima)	5 / 9	GLY A  25 GLY A  24 PHE A  57 GLY A  26 PHE A  55	INS  A 301 (-3.4A) None None INS  A 301 (-3.8A) None	1.32A	4h2fA-5ysqA: undetectable	4h2fA-5ysqA: 9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H2G_A_ADNA603_1 (5'-NUCLEOTIDASE)	5ysq	TM0415 (Thermotoga maritima)	5 / 9	GLY A  25 GLY A  24 PHE A  57 GLY A  26 PHE A  55	INS  A 301 (-3.4A) None None INS  A 301 (-3.8A) None	1.40A	4h2gA-5ysqA: 3.0	4h2gA-5ysqA: 9.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4I90_A_ACTA500_0 (1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	LYS A 113 ARG A 166 TRP A 185	INS  A 402 (-3.9A) INS  A 402 (-2.6A) INS  A 402 ( 4.9A)	0.28A	4i90A-4rv3A: 54.5	4i90A-4rv3A: 99.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J83_A_SAMA401_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	4ru1	MONOSACCHARIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT2 FAMILY (Acidothermus cellulolyticus)	5 / 11	ILE A 113 ALA A 135 GLY A 286 HIS A  57 GLU A  94	None None None INS  A 401 (-4.2A) None	1.45A	4j83A-4ru1A: undetectable	4j83A-4ru1A: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JKS_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4jksA-4xf7A: 24.5	4jksA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JKS_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4jksB-4xf7A: 24.5	4jksB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JKU_A_ADNA500_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4jkuA-4xf7A: 21.7	4jkuA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JKU_B_ADNB500_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4jkuB-4xf7A: 24.5	4jkuB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8C_A_ADNA401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.83A	4k8cA-4xf7A: 21.7	4k8cA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8C_B_ADNB401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4k8cB-4xf7A: 24.5	4k8cB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8K_A_ADNA401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4k8kA-4xf7A: 24.5	4k8kA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8K_B_ADNB403_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4k8kB-4xf7A: 24.5	4k8kB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8P_A_ADNA401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4k8pA-4xf7A: 24.4	4k8pA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8P_B_ADNB401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4k8pB-4xf7A: 24.3	4k8pB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8T_A_ADNA401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4k8tA-4xf7A: 24.4	4k8tA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8T_B_ADNB401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4k8tB-4xf7A: 24.4	4k8tB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K93_A_ADNA401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4k93A-4xf7A: 24.5	4k93A-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K93_B_ADNB402_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4k93B-4xf7A: 24.5	4k93B-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K9C_A_ADNA401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4k9cA-4xf7A: 24.6	4k9cA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K9C_B_ADNB401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.79A	4k9cB-4xf7A: 24.5	4k9cB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K9I_A_ADNA401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4k9iA-4xf7A: 24.5	4k9iA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K9I_B_ADNB401_1 (SUGAR KINASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4k9iB-4xf7A: 24.5	4k9iB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAD_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4kadA-4xf7A: 24.4	4kadA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAD_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.83A	4kadB-4xf7A: 21.6	4kadB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAH_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4kahA-4xf7A: 21.7	4kahA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAH_B_ADNB502_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4kahB-4xf7A: 24.5	4kahB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAL_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4kalA-4xf7A: 24.5	4kalA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAL_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4kalB-4xf7A: 24.4	4kalB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAN_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4kanA-4xf7A: 21.7	4kanA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KAN_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.79A	4kanB-4xf7A: 24.4	4kanB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KBE_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.83A	4kbeA-4xf7A: 21.8	4kbeA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KBE_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4kbeB-4xf7A: 21.6	4kbeB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_B_MTLB806_0 (NITRIC OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 7	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.25A	4kcnB-4irxA: undetectable	4kcnB-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KN2_C_LYAC304_2 (FOLATE RECEPTOR BETA)	5fyr	PHOSPHOINOSITOL-SPEC IFIC PHOSPHOLIPASE C (Pseudomonas sp.)	3 / 3	TYR A 282 GLN A 275 TRP A 262	None None INS  A 301 (-3.8A)	1.02A	4kn2C-5fyrA: undetectable	4kn2C-5fyrA: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBG_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4lbgA-4xf7A: 24.5	4lbgA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBG_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4lbgB-4xf7A: 24.6	4lbgB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBX_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4lbxA-4xf7A: 24.5	4lbxA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBX_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4lbxB-4xf7A: 24.6	4lbxB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LC4_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4lc4A-4xf7A: 24.5	4lc4A-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LC4_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.82A	4lc4B-4xf7A: 24.4	4lc4B-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LCA_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.80A	4lcaA-4xf7A: 24.5	4lcaA-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LCA_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	ASP A  12 GLY A  25 GLY A  26 THR A 215 ASP A 219	INS  A 301 (-2.8A) INS  A 301 (-3.1A) INS  A 301 (-3.1A) INS  A 301 (-4.7A) INS  A 301 (-2.7A)	0.81A	4lcaB-4xf7A: 24.4	4lcaB-4xf7A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MX0_A_BCZA513_1 (NEURAMINIDASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	3 / 3	ARG A 140 ASP A 134 ARG A  85	INS  A 301 (-2.7A) MG  A 303 ( 4.0A) ACP  A 302 (-2.9A)	0.98A	4mx0A-4xf7A: undetectable	4mx0A-4xf7A: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_C_SAMC601_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	ASN A  78 GLY A  26 ILE A  32 SER A   9 PHE A  57	INS  A 301 (-3.0A) INS  A 301 (-3.8A) None INS  A 301 ( 4.5A) None	1.20A	4obwC-5ysqA: 4.5	4obwC-5ysqA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_1 (ADENOSINE KINASE)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	ASP A  11 GLY A  25 GLY A  26 GLN A 141 ASP A 234	INS  A 301 (-2.7A) INS  A 301 (-3.4A) INS  A 301 (-3.8A) INS  A 301 (-3.0A) INS  A 301 ( 4.9A)	1.21A	4ubeA-5ysqA: 26.3	4ubeA-5ysqA: 14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5Q_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 6	ASP A  31 ALA A  46 THR A  48 THR A 252	INS  A 402 ( 4.3A) None None None	0.98A	4w5qA-4rv3A: undetectable	4w5qA-4rv3A: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5R_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 6	ASP A  31 ALA A  46 THR A  48 THR A 252	INS  A 402 ( 4.3A) None None None	0.97A	4w5rA-4rv3A: undetectable	4w5rA-4rv3A: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5T_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 6	ASP A  31 ALA A  46 THR A  48 THR A 252	INS  A 402 ( 4.3A) None None None	0.96A	4w5tA-4rv3A: undetectable	4w5tA-4rv3A: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WH5_A_3QBA204_1 (LINCOSAMIDE RESISTANCE PROTEIN)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	GLY A 231 ASP A 234 PHE A  55 PHE A  57 ALA A  22	INS  A 301 ( 4.7A) INS  A 301 ( 4.9A) None None None	1.41A	4wh5A-5ysqA: undetectable	4wh5A-5ysqA: 17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y9T_A_PA1A401_1 (ABC TRANSPORTER, SOLUTE BINDING PROTEIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	5 / 12	PHE A  52 GLN A  49 ASP A 125 ASP A 258 ALA A  54	None INS  A 401 (-3.0A) INS  A 401 (-2.8A) INS  A 401 (-2.7A) None	1.36A	4y9tA-4irxA: 35.3	4y9tA-4irxA: 25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y9T_A_PA1A401_1 (ABC TRANSPORTER, SOLUTE BINDING PROTEIN)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	5 / 12	PHE A  38 ASP A 112 ARG A 113 TRP A 189 GLN A 263	INS  A 401 (-4.5A) INS  A 401 (-2.6A) INS  A 401 (-3.8A) INS  A 401 (-3.6A) INS  A 401 (-3.3A)	0.80A	4y9tA-4rxmA: 35.5	4y9tA-4rxmA: 24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA906_0 (PROTEIN ARGONAUTE-2)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 6	ASP A  31 ALA A  46 THR A  48 THR A 252	INS  A 402 ( 4.3A) None None None	1.00A	4z4cA-4rv3A: undetectable	4z4cA-4rv3A: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4F_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 6	ASP A  31 ALA A  46 THR A  48 THR A 252	INS  A 402 ( 4.3A) None None None	0.96A	4z4fA-4rv3A: undetectable	4z4fA-4rv3A: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4G_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 5	ASP A  31 ALA A  46 THR A  48 THR A 252	INS  A 402 ( 4.3A) None None None	0.99A	4z4gA-4rv3A: undetectable	4z4gA-4rv3A: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4I_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	4 / 6	ASP A  31 ALA A  46 THR A  48 THR A 252	INS  A 402 ( 4.3A) None None None	0.98A	4z4iA-4rv3A: undetectable	4z4iA-4rv3A: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	5 / 7	LEU A  31 GLN A  69 PHE A  29 LEU A  42 PHE A  38	None None None None INS  A 401 (-4.5A)	1.11A	5b1bP-4rxmA: undetectable 5b1bW-4rxmA: undetectable	5b1bP-4rxmA: 20.81 5b1bW-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BR1_A_X6XA401_1 (ABC TRANSPORTER, BINDING PROTEIN)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	5 / 11	PHE A  38 ASP A 112 ARG A 113 TRP A 189 GLN A 263	INS  A 401 (-4.5A) INS  A 401 (-2.6A) INS  A 401 (-3.8A) INS  A 401 (-3.6A) INS  A 401 (-3.3A)	0.78A	5br1A-4rxmA: 35.4	5br1A-4rxmA: 24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_C_URFC301_1 (BIFUNCTIONAL PROTEIN PYRR)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	ARG A 166 HIS A  30 ARG A  67	INS  A 402 (-2.6A) INS  A 402 (-3.6A) INS  A 402 (-3.5A)	0.73A	5iaoC-4rv3A: undetectable	5iaoC-4rv3A: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_F_URFF301_1 (BIFUNCTIONAL PROTEIN PYRR)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	ARG A 166 HIS A  30 ARG A  67	INS  A 402 (-2.6A) INS  A 402 (-3.6A) INS  A 402 (-3.5A)	0.75A	5iaoF-4rv3A: undetectable	5iaoF-4rv3A: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KBW_B_RBFB201_1 (RIBOFLAVIN TRANSPORTER RIBU)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	5 / 12	LEU A  77 ASP A 219 GLY A 216 VAL A  10 LYS A  16	INS  A 301 ( 4.8A) INS  A 301 (-2.7A) ACP  A 302 (-3.9A) INS  A 301 ( 4.8A) None	1.33A	5kbwB-4xf7A: undetectable	5kbwB-4xf7A: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KGP_A_GCSA407_1 (PREDICTED ACETYLTRANSFERASE)	4ru1	MONOSACCHARIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT2 FAMILY (Acidothermus cellulolyticus)	4 / 8	ARG A 190 GLU A 156 GLY A 312 PRO A 313	INS  A 401 (-2.6A) None None None	1.01A	5kgpA-4ru1A: undetectable	5kgpA-4ru1A: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KGP_B_GCSB405_1 (PREDICTED ACETYLTRANSFERASE)	4ru1	MONOSACCHARIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT2 FAMILY (Acidothermus cellulolyticus)	4 / 8	ARG A 190 GLU A 156 GLY A 312 PRO A 313	INS  A 401 (-2.6A) None None None	1.03A	5kgpB-4ru1A: undetectable	5kgpB-4ru1A: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KVA_A_SAMA301_1 (CAFFEOYL-COA O-METHYLTRANSFERASE)	2huo	INOSITOL OXYGENASE (Mus musculus)	3 / 3	THR A 143 SER A 221 ASP A  85	None INS  A 303 (-2.8A) INS  A 303 (-2.7A)	0.84A	5kvaA-2huoA: undetectable	5kvaA-2huoA: 17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KVA_B_SAMB301_1 (CAFFEOYL-COA O-METHYLTRANSFERASE)	2huo	INOSITOL OXYGENASE (Mus musculus)	3 / 3	THR A 143 SER A 221 ASP A  85	None INS  A 303 (-2.8A) INS  A 303 (-2.7A)	0.84A	5kvaB-2huoA: undetectable	5kvaB-2huoA: 17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L1F_A_6ZPA902_1 (GLUTAMATE RECEPTOR 2)	2huo	INOSITOL OXYGENASE (Mus musculus)	4 / 8	ASP A 142 PRO A 224 TYR A 231 SER A 159	INS  A 303 (-3.5A) None None None	1.09A	5l1fA-2huoA: undetectable 5l1fB-2huoA: undetectable	5l1fA-2huoA: 16.53 5l1fB-2huoA: 16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L1F_C_6ZPC902_1 (GLUTAMATE RECEPTOR 2)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 7	SER A 174 PHE A  52 SER A 203 ASN A 168	INS  A 401 (-2.5A) None INS  A 401 (-2.7A) INS  A 401 (-3.8A)	1.17A	5l1fC-4irxA: 15.3	5l1fC-4irxA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N9X_A_THRA601_0 (ADENYLATION DOMAIN)	5ysq	TM0415 (Thermotoga maritima)	4 / 7	PHE A  57 PHE A  55 GLY A  24 GLY A  26	None None None INS  A 301 (-3.8A)	1.03A	5n9xA-5ysqA: 3.2	5n9xA-5ysqA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_B_CUB601_0 (THIOCYANATE DEHYDROGENASE)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	HIS A  80 ASP A  31 HIS A  30	None INS  A 402 ( 4.3A) INS  A 402 (-3.6A)	0.71A	5oexB-4rv3A: undetectable	5oexB-4rv3A: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_C_CUC601_0 (THIOCYANATE DEHYDROGENASE)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	HIS A  80 ASP A  31 HIS A  30	None INS  A 402 ( 4.3A) INS  A 402 (-3.6A)	0.69A	5oexC-4rv3A: undetectable	5oexC-4rv3A: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_D_CUD601_0 (THIOCYANATE DEHYDROGENASE)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	HIS A  80 ASP A  31 HIS A  30	None INS  A 402 ( 4.3A) INS  A 402 (-3.6A)	0.67A	5oexD-4rv3A: undetectable	5oexD-4rv3A: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OV9_B_CVIB603_0 (ACETYLCHOLINESTERASE)	4xf7	CARBOHYDRATE/PYRIMID INE KINASE, PFKB FAMILY (Thermococcus kodakarensis)	4 / 7	TYR A  30 TYR A  29 GLN A 136 ASP A 134	INS  A 301 (-4.6A) None MG  A 303 ( 2.9A) MG  A 303 ( 4.0A)	1.29A	5ov9B-4xf7A: undetectable	5ov9B-4xf7A: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUN_A_MTLA805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.26A	5vunA-4irxA: undetectable	5vunA-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUN_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.25A	5vunB-4irxA: undetectable	5vunB-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.23A	5vuoB-4irxA: undetectable	5vuoB-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 5	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.98A	5x19C-4rxmA: undetectable 5x19J-4rxmA: undetectable	5x19C-4rxmA: 20.81 5x19J-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_P_CHDP304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 7	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.97A	5x1fP-4rxmA: undetectable 5x1fW-4rxmA: undetectable	5x1fP-4rxmA: 20.81 5x1fW-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y2T_B_8LXB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	PHE A  51 SER A 174 HIS A 137 PHE A  52	INS  A 401 (-3.5A) INS  A 401 (-2.5A) None None	0.97A	5y2tB-4irxA: undetectable	5y2tB-4irxA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJS_A_SALA603_0 (VICILIN-LIKE ANTIMICROBIAL PEPTIDES 2-2)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	5 / 11	GLY A 145 ASN A 168 ARG A 178 VAL A 182 GLY A 146	None INS  A 401 (-3.8A) INS  A 401 (-3.0A) None None	1.47A	5yjsA-4irxA: undetectable	5yjsA-4irxA: 12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA409_0 (UNCHARACTERIZED PROTEIN KDOO)	4rv3	1-PHOSPHATIDYLINOSIT OL PHOSPHODIESTERASE (Staphylococcus aureus)	3 / 3	ASP A  31 PHE A 239 ARG A 166	INS  A 402 ( 4.3A) INS  A 402 ( 4.1A) INS  A 402 (-2.6A)	1.08A	5yw0A-4rv3A: undetectable	5yw0A-4rv3A: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 7	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.93A	5zcoC-4rxmA: undetectable 5zcoJ-4rxmA: undetectable	5zcoC-4rxmA: 20.81 5zcoJ-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	4 / 7	LEU A  31 PHE A  29 LEU A  42 PHE A  38	None None None INS  A 401 (-4.5A)	0.95A	5zcqC-4rxmA: undetectable 5zcqJ-4rxmA: undetectable	5zcqC-4rxmA: 20.81 5zcqJ-4rxmA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6APH_A_ADNA501_1 (ADENOSYLHOMOCYSTEINA SE)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.46A	6aphA-2huoA: undetectable	6aphA-2huoA: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUU_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 8	ASN A 231 GLN A 278 ASN A  45 ASP A 125	INS  A 401 (-3.9A) INS  A 401 (-3.1A) None INS  A 401 (-2.8A)	1.27A	6auuB-4irxA: undetectable	6auuB-4irxA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	4rxm	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN (Mannheimia haemolytica)	5 / 10	HIS A 123 ALA A 109 PRO A  32 PHE A  38 VAL A 269	None None None INS  A 401 (-4.5A) None	0.99A	6b89B-4rxmA: 2.5	6b89B-4rxmA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CLX_A_SAMA401_0 (O-METHYLTRANSFERASE)	4ru1	MONOSACCHARIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT2 FAMILY (Acidothermus cellulolyticus)	5 / 12	ASP A 279 ARG A 190 ALA A 159 GLY A 153 GLY A 312	None INS  A 401 (-2.6A) None None None	0.97A	6clxA-4ru1A: 2.2	6clxA-4ru1A: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	4irx	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN (Caulobacter vibrioides)	4 / 7	ASN A 168 ALA A 274 VAL A 226 LEU A 228	INS  A 401 (-3.8A) None None None	0.75A	6dwnB-4irxA: undetectable	6dwnB-4irxA: 14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3M_C_ADNC502_1 (-)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.40A	6f3mC-2huoA: undetectable	6f3mC-2huoA: 18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5fyr	PHOSPHOINOSITOL-SPEC IFIC PHOSPHOLIPASE C (Pseudomonas sp.)	4 / 8	ASP A  50 ARG A 260 VAL A  44 GLN A 275	CA  A 401 (-2.2A) INS  A 301 (-2.9A) None None	1.05A	6fbvD-5fyrA: undetectable	6fbvD-5fyrA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_B_ADNB501_1 (-)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.44A	6gbnB-2huoA: undetectable	6gbnB-2huoA: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_C_ADNC501_1 (-)	2huo	INOSITOL OXYGENASE (Mus musculus)	5 / 12	ASP A  88 LYS A 127 ASP A 124 LEU A 254 HIS A 123	INS  A 303 (-3.7A) INS  A 303 (-2.6A) FE  A 302 ( 2.5A) None FE  A 301 ( 3.2A)	1.43A	6gbnC-2huoA: undetectable	6gbnC-2huoA: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNF_C_QPSC602_2 (-)	5ysq	TM0415 (Thermotoga maritima)	5 / 12	VAL A  28 ASP A  11 GLU A 176 GLU A 120 GLY A   6	None INS  A 301 (-2.7A) SO4  A 302 ( 4.9A) None None	1.46A	6gnfC-5ysqA: 6.9	6gnfC-5ysqA: 9.21