SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IFA'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DVT_A_FLPA125_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 8 | LEU A 17LEU A 110SER A 117THR A 119 | IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.32A | 1dvtA-3fc8A:24.11dvtB-3fc8A:23.0 | 1dvtA-3fc8A:99.191dvtB-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DVT_A_FLPA125_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 8 | LYS A 15LEU A 17ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.76A | 1dvtA-3fc8A:24.11dvtB-3fc8A:23.0 | 1dvtA-3fc8A:99.191dvtB-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DVX_B_DIFB125_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 7 | LEU A 17LEU A 110SER A 115SER A 117 | IFA A3000 ( 4.7A)IFA A3000 (-4.1A)NoneIFA A3000 (-3.9A) | 0.82A | 1dvxA-3fc8A:24.2 | 1dvxA-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DVX_B_DIFB125_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 7 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 115THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)NoneIFA A3000 ( 4.9A) | 0.80A | 1dvxA-3fc8A:24.2 | 1dvxA-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DVX_B_DIFB125_2 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 7 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A)None | 0.69A | 1dvxB-3fc8A:23.1 | 1dvxB-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETA_1_T441128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 5 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.70A | 1eta1-3fc8A:22.5 | 1eta1-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETA_2_T442129_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 5 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.70A | 1eta2-3fc8A:21.3 | 1eta2-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETB_1_T441128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 6 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.72A | 1etb1-3fc8A:23.3 | 1etb1-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETB_2_T442129_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17GLU A 54THR A 106ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.67A | 1etb2-3fc8A:22.3 | 1etb2-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1F86_A_T44A428_1 (TRANSTHYRETINTHR119MET VARIANT) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A) | 1.20A | 1f86A-3fc8A:24.3 | 1f86A-3fc8A:99.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1F86_B_T44B528_1 (TRANSTHYRETINTHR119MET VARIANT) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.78A | 1f86B-3fc8A:23.0 | 1f86B-3fc8A:99.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ICT_C_T44C128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 7 / 11 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110THR A 119VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A)None | 0.72A | 1ictA-3fc8A:22.91ictC-3fc8A:22.9 | 1ictA-3fc8A:100.001ictC-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ICT_D_T44D129_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.66A | 1ictB-3fc8A:22.7 | 1ictB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ICT_D_T44D129_2 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LEU A 17THR A 106LEU A 110THR A 119VAL A 121 | IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A)None | 0.49A | 1ictD-3fc8A:22.7 | 1ictD-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IE4_A_T44A128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 10 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.62A | 1ie4A-3fc8A:22.61ie4C-3fc8A:22.6 | 1ie4A-3fc8A:83.871ie4C-3fc8A:83.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IE4_A_T44A128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 10 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.76A | 1ie4A-3fc8A:22.61ie4C-3fc8A:22.6 | 1ie4A-3fc8A:83.871ie4C-3fc8A:83.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IE4_B_T44B328_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 8 | LYS A 15GLU A 54ALA A 108LEU A 110 | IFA A3000 (-3.0A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.67A | 1ie4B-3fc8A:22.31ie4D-3fc8A:22.3 | 1ie4B-3fc8A:83.871ie4D-3fc8A:83.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IE4_B_T44B328_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 8 | LYS A 15GLU A 54ALA A 108THR A 119 | IFA A3000 (-3.0A)NoneIFA A3000 (-3.1A)IFA A3000 ( 4.9A) | 0.76A | 1ie4B-3fc8A:22.31ie4D-3fc8A:22.3 | 1ie4B-3fc8A:83.871ie4D-3fc8A:83.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1SN5_C_T3C601_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 6 | GLU A 54ALA A 108LEU A 110VAL A 121 | NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.62A | 1sn5A-3fc8A:20.7 | 1sn5A-3fc8A:55.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1SN5_C_T3C601_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 6 | LEU A 17ALA A 108LEU A 110VAL A 121 | IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.53A | 1sn5A-3fc8A:20.7 | 1sn5A-3fc8A:55.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1SN5_C_T3C601_2 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 8 | LEU A 17GLU A 54THR A 106ALA A 108LEU A 110VAL A 121 | IFA A3000 ( 4.7A)NoneIFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.68A | 1sn5C-3fc8A:20.5 | 1sn5C-3fc8A:55.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1SN5_C_T3C601_2 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 8 | LYS A 15LEU A 17GLU A 54THR A 106LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-4.9A)IFA A3000 (-4.1A) | 1.05A | 1sn5C-3fc8A:20.5 | 1sn5C-3fc8A:55.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1SN5_D_T3D602_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 12 | LEU A 17GLU A 54ALA A 108LEU A 110VAL A 121 | IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.67A | 1sn5B-3fc8A:20.91sn5D-3fc8A:21.0 | 1sn5B-3fc8A:55.121sn5D-3fc8A:55.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1SN5_D_T3D602_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 12 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.93A | 1sn5B-3fc8A:20.91sn5D-3fc8A:21.0 | 1sn5B-3fc8A:55.121sn5D-3fc8A:55.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1SN5_D_T3D602_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 12 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.97A | 1sn5B-3fc8A:20.91sn5D-3fc8A:21.0 | 1sn5B-3fc8A:55.121sn5D-3fc8A:55.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TT6_A_DESA129_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.63A | 1tt6A-3fc8A:23.3 | 1tt6A-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TT6_B_DESB128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 5 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.58A | 1tt6B-3fc8A:24.6 | 1tt6B-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TYR_A_9CRA131_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.74A | 1tyrA-3fc8A:22.4 | 1tyrA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TYR_A_9CRA131_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 6 | LYS A 15LEU A 17LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.98A | 1tyrA-3fc8A:22.4 | 1tyrA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TYR_B_9CRB130_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 7 | LYS A 15LEU A 17LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.71A | 1tyrB-3fc8A:21.5 | 1tyrB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TYR_B_9CRB130_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 7 | LYS A 15LEU A 17THR A 106ALA A 108LEU A 110VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.48A | 1tyrB-3fc8A:21.5 | 1tyrB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TZ8_B_DESB128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 11 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.74A | 1tz8A-3fc8A:23.31tz8B-3fc8A:23.5 | 1tz8A-3fc8A:100.001tz8B-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TZ8_B_DESB128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 11 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.73A | 1tz8A-3fc8A:23.31tz8B-3fc8A:23.5 | 1tz8A-3fc8A:100.001tz8B-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TZ8_C_DESC129_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.69A | 1tz8C-3fc8A:23.31tz8D-3fc8A:23.8 | 1tz8C-3fc8A:100.001tz8D-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TZ8_D_DESD128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.97A | 1tz8D-3fc8A:23.8 | 1tz8D-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ROX_A_T44A128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A) | 0.81A | 2roxA-3fc8A:23.2 | 2roxA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ROX_B_T44B128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17GLU A 54ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.70A | 2roxB-3fc8A:22.2 | 2roxB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CFQ_A_DIFA1_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 6 | LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.76A | 3cfqA-3fc8A:24.0 | 3cfqA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CFQ_A_DIFA1_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.88A | 3cfqA-3fc8A:24.0 | 3cfqA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CFQ_B_DIFB1_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.70A | 3cfqA-3fc8A:24.03cfqB-3fc8A:23.0 | 3cfqA-3fc8A:100.003cfqB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CFQ_B_DIFB1_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.48A | 3cfqA-3fc8A:24.03cfqB-3fc8A:23.0 | 3cfqA-3fc8A:100.003cfqB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3D2T_B_1FLB500_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15ALA A 108LEU A 110SER A 117THR A 119VAL A 121 | IFA A3000 (-3.0A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A)None | 0.40A | 3d2tB-3fc8A:22.6 | 3d2tB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OZK_A_T44A128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 9 | MET A 13LEU A 17ALA A 108LEU A 110THR A 118 | NoneIFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 1.47A | 3ozkA-3fc8A:24.0 | 3ozkA-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OZK_A_T44A128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 8 / 9 | MET A 13LYS A 15LEU A 17THR A 106ALA A 108LEU A 110THR A 119VAL A 121 | NoneIFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A)None | 0.56A | 3ozkA-3fc8A:24.0 | 3ozkA-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OZK_B_T44B128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LEU A 17ALA A 108LEU A 110THR A 119VAL A 121 | IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A)None | 0.47A | 3ozkB-3fc8A:23.4 | 3ozkB-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OZK_B_T44B128_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LYS A 15LEU A 17ALA A 108LEU A 110VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.82A | 3ozkB-3fc8A:23.4 | 3ozkB-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4D7B_A_TCWA1126_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.30A | 4d7bB-3fc8A:23.9 | 4d7bB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4D7B_B_TCWB1126_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LYS A 15LEU A 17LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.73A | 4d7bA-3fc8A:23.7 | 4d7bA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4D7B_B_TCWB1126_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 7 | LYS A 15LEU A 17THR A 106ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.22A | 4d7bA-3fc8A:23.7 | 4d7bA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4I89_A_1FLA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.64A | 4i89A-3fc8A:24.2 | 4i89A-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4I89_B_1FLB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15ALA A 108SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 (-3.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.13A | 4i89B-3fc8A:22.9 | 4i89B-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IIZ_A_LURA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 3 / 3 | LYS A 15LEU A 17ALA A 108 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A) | 0.28A | 4iizA-3fc8A:23.2 | 4iizA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IIZ_B_LURB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 8 / 8 | MET A 13LYS A 15LEU A 17GLU A 54THR A 106ALA A 108LEU A 110VAL A 121 | NoneIFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.65A | 4iizB-3fc8A:22.4 | 4iizB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IK6_A_LURA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17ALA A 108VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)None | 0.36A | 4ik6A-3fc8A:23.4 | 4ik6A-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IK6_B_LURB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 8 / 8 | MET A 13LYS A 15LEU A 17GLU A 54THR A 106ALA A 108LEU A 110VAL A 121 | NoneIFA A3000 (-3.0A)IFA A3000 ( 4.7A)NoneIFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.52A | 4ik6B-3fc8A:22.6 | 4ik6B-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IK7_A_IMNA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | MET A 13LYS A 15LEU A 17ALA A 108THR A 118 | NoneIFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)None | 1.30A | 4ik7A-3fc8A:23.7 | 4ik7A-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IK7_A_IMNA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 7 / 7 | MET A 13LYS A 15LEU A 17THR A 106ALA A 108THR A 119VAL A 121 | NoneIFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 ( 4.9A)None | 0.52A | 4ik7A-3fc8A:23.7 | 4ik7A-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IK7_B_IMNB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 7 / 8 | LYS A 15LEU A 17THR A 106ALA A 108LEU A 110THR A 119VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A)None | 0.75A | 4ik7B-3fc8A:22.7 | 4ik7B-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IKI_B_IMNB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.78A | 4ikiB-3fc8A:23.0 | 4ikiB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IKI_B_IMNB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 6 | LYS A 15LEU A 17LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 1.04A | 4ikiB-3fc8A:23.0 | 4ikiB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IKJ_A_SUZA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.63A | 4ikjA-3fc8A:23.64ikjB-3fc8A:22.6 | 4ikjA-3fc8A:100.004ikjB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IKK_B_SUZB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.90A | 4ikkA-3fc8A:23.34ikkB-3fc8A:22.4 | 4ikkA-3fc8A:100.004ikkB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IKL_A_SUZA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 7 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.63A | 4iklA-3fc8A:24.14iklB-3fc8A:23.1 | 4iklA-3fc8A:100.004iklB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IKL_B_SUZB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 8 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 ( 4.9A) | 0.89A | 4iklA-3fc8A:24.14iklB-3fc8A:23.1 | 4iklA-3fc8A:100.004iklB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4PWJ_A_30ZA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17THR A 106ALA A 108LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.66A | 4pwjA-3fc8A:23.7 | 4pwjA-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4PWJ_B_30ZB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 7 | LEU A 17THR A 106ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.38A | 4pwjB-3fc8A:23.5 | 4pwjB-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4PWJ_B_30ZB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 7 | LYS A 15LEU A 17THR A 106ALA A 108LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.70A | 4pwjB-3fc8A:23.5 | 4pwjB-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5A6I_A_TCWA1124_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.46A | 5a6iA-3fc8A:23.5 | 5a6iA-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5A6I_A_TCWA1124_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 6 | LYS A 15LEU A 17LEU A 110SER A 117 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.1A)IFA A3000 (-3.9A) | 0.77A | 5a6iA-3fc8A:23.5 | 5a6iA-3fc8A:99.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5BOJ_A_4TXA201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.51A | 5bojA-3fc8A:24.1 | 5bojA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5BOJ_B_4TXB201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 7 / 7 | LYS A 15LEU A 17THR A 106ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-4.9A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.46A | 5bojB-3fc8A:22.8 | 5bojB-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5CR1_A_T44A201_1 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 5 / 5 | LYS A 15LEU A 17ALA A 108LEU A 110VAL A 121 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)None | 0.78A | 5cr1A-3fc8A:24.2 | 5cr1A-3fc8A:99.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5L4I_A_6J3A201_0 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.34A | 5l4iA-3fc8A:24.1 | 5l4iA-3fc8A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5L4I_B_6J3B201_0 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 6 / 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.30A | 5l4iB-3fc8A:22.8 | 5l4iB-3fc8A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GBF_A_ACTA507_0 (MOLYBDOPTERINBIOSYNTHESIS PROTEINCNX1) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 3 / 3 | LYS A 15SER A 50SER A 52 | IFA A3000 (-3.0A)NoneNone | 0.85A | 6gbfA-3fc8A:undetectable | 6gbfA-3fc8A:15.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6GNR_A_6J3A201_0 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A) | 1.01A | 6gnrA-3fc8A:21.0 | 6gnrA-3fc8A:54.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6GNR_B_6J3B201_0 (TRANSTHYRETIN) |
3fc8 | TRANSTHYRETIN (Homosapiens) | 4 / 4 | LYS A 15LEU A 17ALA A 108LEU A 110 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A) | 1.01A | 6gnrB-3fc8A:20.9 | 6gnrB-3fc8A:54.55 |